Published in Lancet on January 24, 1991
The Trojan exosome hypothesis. Proc Natl Acad Sci U S A (2003) 3.45
Inhibition of HIV-1 entry by antibodies: potential viral and cellular targets. J Intern Med (2007) 1.41
Protection in simian immunodeficiency virus-vaccinated monkeys correlates with anti-HLA class I antibody response. J Exp Med (1992) 1.38
Inactivated whole-virus vaccine derived from a proviral DNA clone of simian immunodeficiency virus induces high levels of neutralizing antibodies and confers protection against heterologous challenge. Proc Natl Acad Sci U S A (1992) 1.35
Replication and persistence of simian immunodeficiency virus variants after passage in macaque lymphocytes and established human cell lines. J Virol (1993) 1.15
Vaccine-induced neutralizing antibodies directed in part to the simian immunodeficiency virus (SIV) V2 domain were unable to protect rhesus monkeys from SIV experimental challenge. J Virol (1994) 1.10
Generation of CD8 suppressor factor and beta chemokines, induced by xenogeneic immunization, in the prevention of simian immunodeficiency virus infection in macaques. Proc Natl Acad Sci U S A (1998) 1.07
CD8+ lymphocytes do not mediate protection against acute superinfection 20 days after vaccination with a live attenuated simian immunodeficiency virus. J Virol (2005) 1.05
Monkey business over AIDS vaccine. BMJ (1991) 0.95
T- and B-cell functions and epitope expression in nonhuman primates immunized with simian immunodeficiency virus antigen by the rectal route. Proc Natl Acad Sci U S A (1993) 0.89
Antibodies to human and non-human primate cellular and culture medium components in macaques vaccinated with the simian immunodeficiency virus. Immunology (1994) 0.88
Induction of humoral and cell-mediated anti-human immunodeficiency virus (HIV) responses in HIV sero-negative volunteers by immunization with recombinant gp160. J Clin Invest (1993) 0.87
Quantitation of HLA proteins incorporated by human immunodeficiency virus type 1 and assessment of neutralizing activity of anti-HLA antibodies. J Virol (2007) 0.85
Three epitopic peptides of the simian immunodeficiency virus Nef protein recognized by macaque cytolytic T lymphocytes. J Virol (1992) 0.84
The role of innate APOBEC3G and adaptive AID immune responses in HLA-HIV/SIV immunized SHIV infected macaques. PLoS One (2012) 0.82
Immunization with recombinant HLA classes I and II, HIV-1 gp140, and SIV p27 elicits protection against heterologous SHIV infection in rhesus macaques. J Virol (2011) 0.80
Heterologous protection elicited by candidate monomeric recombinant HIV-1 gp120 vaccine in the absence of cross neutralising antibodies in a macaque model. Retrovirology (2012) 0.79
Cytoskeletal proteins bound to heat-shock protein 70 may elicit resistance to simian immunodeficiency virus infection of CD4(+) T cells. Immunology (2009) 0.78
Mucosal challenge with cell-associated or cell-free feline immunodeficiency virus induces rapid and distinctly different patterns of phenotypic change in the mucosal and systemic immune systems. Immunology (2007) 0.76
Characteristics of a pathogenic molecular clone of an end-stage serum-derived variant of simian immunodeficiency virus (SIV(F359)). J Virol (2001) 0.76
AIDS vaccine development: let a thousand flowers bloom. J Clin Pathol (1998) 0.75
Transcomplementation of simian immunodeficiency virus Rev with human T-cell leukemia virus type I Rex. J Virol (1993) 0.75
AIDS vaccine: new ideas from old approaches. J R Soc Med (2003) 0.75
AIDS vaccine: hope and despair. Lancet (1991) 0.75
Complement-mediated virus infectivity neutralisation by HLA antibodies is associated with sterilising immunity to SIV challenge in the macaque model for HIV/AIDS. PLoS One (2014) 0.75
Prior mucosal exposure to heterologous cells alters the pathogenesis of cell-associated mucosal feline immunodeficiency virus challenge. Retrovirology (2010) 0.75
Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: nested case-control study. Circulation (2002) 3.63
Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells. J Exp Med (1998) 3.53
Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells. Lancet (1995) 3.47
Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques. Nat Med (1996) 2.96
Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J Clin Invest (1996) 2.96
Infectivity in mouse fibroblasts of polyoma DNA integrated into plasmid pBR322 or lambdoid phage DNA. Nature (1979) 2.92
Genetic basis of attenuation of the Sabin type 3 oral poliovirus vaccine. J Virol (1989) 2.89
A proinflammatory role for IL-18 in rheumatoid arthritis. J Clin Invest (1999) 2.65
Selective expression and functions of interleukin 18 receptor on T helper (Th) type 1 but not Th2 cells. J Exp Med (1998) 2.40
Effective immunization against Bordetella pertussis respiratory infection in mice is dependent on induction of cell-mediated immunity. Infect Immun (1993) 2.36
Early suppression of SIV replication by CD8+ nef-specific cytotoxic T cells in vaccinated macaques. Nat Med (1995) 2.23
The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: potential therapy for cancer. Cancer Res (2001) 2.06
Macrophage activation by interferon-gamma from host-protective T cells is inhibited by interleukin (IL)3 and IL4 produced by disease-promoting T cells in leishmaniasis. Eur J Immunol (1989) 2.04
Inhibition of estrogen receptor-DNA binding by the "pure" antiestrogen ICI 164,384 appears to be mediated by impaired receptor dimerization. Proc Natl Acad Sci U S A (1990) 2.03
Long-term ecosystem stress: the effects of years of experimental acidification on a small lake. Science (1985) 2.03
Recombinant vaccine-induced protection against the highly pathogenic simian immunodeficiency virus SIV(mac251): dependence on route of challenge exposure. J Virol (1998) 1.98
A new fluorometric assay for cytotoxicity measurements in-vitro. Int J Oncol (1993) 1.96
A system for data processing in haematology. J Clin Pathol (1974) 1.95
Bordetella pertussis respiratory infection in children is associated with preferential activation of type 1 T helper cells. J Infect Dis (1997) 1.92
Atypical disease after Bordetella pertussis respiratory infection of mice with targeted disruptions of interferon-gamma receptor or immunoglobulin mu chain genes. J Exp Med (1997) 1.81
Protective immunization of mice with specific HSV-1 glycoproteins. Immunology (1983) 1.77
Molecular and biological characterization of simian immunodeficiency virus macaque strain 32H proviral clones containing nef size variants. J Gen Virol (1994) 1.77
Distinct T-cell subtypes induced with whole cell and acellular pertussis vaccines in children. Immunology (1998) 1.75
Induction of immunoglobulin G Fc receptors by recombinant vaccinia viruses expressing glycoproteins E and I of herpes simplex virus type 1. J Virol (1990) 1.73
Fasciola hepatica suppresses a protective Th1 response against Bordetella pertussis. Infect Immun (1999) 1.69
Herpes simplex virus infection causes the accumulation of a heat-shock protein. EMBO J (1984) 1.67
Use of a computer for producing microbiological reports and for data storage and processing. J Clin Pathol (1975) 1.67
Interleukin-12 is produced by macrophages in response to live or killed Bordetella pertussis and enhances the efficacy of an acellular pertussis vaccine by promoting induction of Th1 cells. Infect Immun (1996) 1.61
Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member. Biochem Biophys Res Commun (2000) 1.59
Direct anti-inflammatory effect of a bacterial virulence factor: IL-10-dependent suppression of IL-12 production by filamentous hemagglutinin from Bordetella pertussis. Eur J Immunol (2000) 1.56
Structural and kinetic characterization of a beta-lactamase-inhibitor protein. Nature (1994) 1.53
Reversion of the attenuated and temperature-sensitive phenotypes of the Sabin type 3 strain of poliovirus in vaccinees. Virology (1989) 1.53
Mucosal vaccines: non toxic derivatives of LT and CT as mucosal adjuvants. Vaccine (2001) 1.49
Anti-major histocompatibility complex antibody responses to simian B cells do not protect macaques against SIVmac infection. AIDS Res Hum Retroviruses (1997) 1.48
OAS1: a multiple sclerosis susceptibility gene that influences disease severity. Neurology (2010) 1.45
Pertussis toxin potentiates Th1 and Th2 responses to co-injected antigen: adjuvant action is associated with enhanced regulatory cytokine production and expression of the co-stimulatory molecules B7-1, B7-2 and CD28. Int Immunol (1998) 1.44
Comparison of the genomes of the wild-type French viscerotropic strain of yellow fever virus with its vaccine derivative French neurotropic vaccine. J Gen Virol (1995) 1.44
Androgen regulation by the long terminal repeat of mouse mammary tumor virus. Mol Cell Biol (1986) 1.43
Early-morning hyperglycemia in IDDM. Acute effects of cholinergic blockade. Diabetes Care (1989) 1.41
Protection in simian immunodeficiency virus-vaccinated monkeys correlates with anti-HLA class I antibody response. J Exp Med (1992) 1.38
Conformational-dependent recognition of influenza virus hemagglutinin by murine T helper clones. Eur J Immunol (1986) 1.37
Studies on the specificity of the vaccine effect elicited by inactivated simian immunodeficiency virus. AIDS Res Hum Retroviruses (1993) 1.34
A short gamma-ray burst apparently associated with an elliptical galaxy at redshift z = 0.225. Nature (2005) 1.32
The association of GRB 060218 with a supernova and the evolution of the shock wave. Nature (2006) 1.32
Fasciola hepatica infection downregulates Th1 responses in mice. Parasite Immunol (2000) 1.32
A mechanism for the insertion of complement component C9 into target membranes. Mol Immunol (1986) 1.30
Live attenuated simian immunodeficiency virus (SIV)mac in macaques can induce protection against mucosal infection with SIVsm. AIDS (1998) 1.27
Cuticular hydrocarbons of dampwood termites,Zootermopsis: Intra- and intercolony variation and potential as taxonomic characters. J Chem Ecol (1988) 1.26
Compartmentalization of T cell responses following respiratory infection with Bordetella pertussis: hyporesponsiveness of lung T cells is associated with modulated expression of the co-stimulatory molecule CD28. Eur J Immunol (1998) 1.19
Extensive diversity in the recognition of influenza virus hemagglutinin by murine T helper clones. J Exp Med (1986) 1.18
Analysis of a yellow fever virus isolated from a fatal case of vaccine-associated human encephalitis. J Infect Dis (1994) 1.18
Protection against Bordetella pertussis in mice in the absence of detectable circulating antibody: implications for long-term immunity in children. J Infect Dis (2000) 1.17
Modulation of innate and acquired immune responses by Escherichia coli heat-labile toxin: distinct pro- and anti-inflammatory effects of the nontoxic AB complex and the enzyme activity. J Immunol (2000) 1.16
Mice lacking inducible nitric-oxide synthase are more susceptible to herpes simplex virus infection despite enhanced Th1 cell responses. J Gen Virol (1998) 1.16
Helper T cells induced by an immunopurified herpes simplex virus type I (HSV-I) 115 kilodalton glycoprotein (gB) protect mice against HSV-I infection. J Exp Med (1985) 1.15
Protective effect on Leishmania major infection of migration inhibitory factor, TNF-alpha, and IFN-gamma administered orally via attenuated Salmonella typhimurium. J Immunol (1998) 1.15
Immunomodulators and delivery systems for vaccination by mucosal routes. Trends Biotechnol (2001) 1.14
Antibacterial properties of Ro 40-6890, a broad-spectrum cephalosporin, and its novel orally absorbable ester, Ro 41-3399. Antimicrob Agents Chemother (1992) 1.13
Enhancement of the anti-herpetic effect of trichosanthin by acyclovir and interferon. FEBS Lett (2001) 1.13
Inhibition of nitric oxide generation affects the induction of diabetes by streptozocin in mice. Biochem Biophys Res Commun (1991) 1.12
Booster immunization of children with an acellular pertussis vaccine enhances Th2 cytokine production and serum IgE responses against pertussis toxin but not against common allergens. Clin Exp Immunol (2000) 1.12
A new gamma-ray burst classification scheme from GRB 060614. Nature (2006) 1.11
Isolation of cDNA clones derived from a cellular gene transcriptionally induced by herpes simplex virus. Nucleic Acids Res (1986) 1.10
Utilization of colorectal cancer screening tests: a 1997 survey of Massachusetts internists. Prev Med (2001) 1.08
Sequence variation in the env gene of simian immunodeficiency virus recovered from immunized macaques is predominantly in the V1 region. J Gen Virol (1993) 1.07
Corticotropin-releasing factor innervation of the locus coeruleus region: distribution of fibers and sources of input. Neuroscience (1992) 1.07
The adjuvant combination monophosphoryl lipid A and QS21 switches T cell responses induced with a soluble recombinant HIV protein from Th2 to Th1. Vaccine (1999) 1.06
Bordetella pertussis-specific Th1/Th2 cells generated following respiratory infection or immunization with an acellular vaccine: comparison of the T cell cytokine profiles in infants and mice. Dev Biol Stand (1997) 1.05
[Tracheal rupture after orotracheal intubation in intensive care]. Ann Fr Anesth Reanim (2007) 1.05
Induction of simian immunodeficiency virus (SIV)-specific CTL in rhesus macaques by vaccination with modified vaccinia virus Ankara expressing SIV transgenes: influence of pre-existing anti-vector immunity. J Gen Virol (2001) 1.04
Characteristics of the human heart: design requirements for replacement. Trans Am Soc Artif Intern Organs (1971) 1.04
Fasciola hepatica cathepsin L cysteine proteinase suppresses Bordetella pertussis-specific interferon-gamma production in vivo. Parasite Immunol (2001) 1.03
Dysregulation of monocytic nuclear factor-kappa B by oxidized low-density lipoprotein. Arterioscler Thromb Vasc Biol (1997) 1.01
Diversity of the class II (I-Ak/I-Ek)-restricted T cell repertoire for influenza hemagglutinin and antigenic drift. Six nonoverlapping epitopes on the HA1 subunit are defined by synthetic peptides. J Exp Med (1989) 1.00
Sodium regulation in the freshwater mollusc Limnaea stagnalis (L.) (Gastropoda: Pulmonata). J Exp Biol (1970) 1.00
Phase III trial of accelerated hyperfractionation with or without difluromethylornithine (DFMO) versus standard fractionated radiotherapy with or without DFMO for newly diagnosed patients with glioblastoma multiforme. Int J Radiat Oncol Biol Phys (2001) 1.00
Interferon-gamma mediated immune effector mechanisms against Bordetella pertussis. Immunol Lett (1999) 0.99
Mutants of Escherichia coli heat-labile toxin act as effective mucosal adjuvants for nasal delivery of an acellular pertussis vaccine: differential effects of the nontoxic AB complex and enzyme activity on Th1 and Th2 cells. Infect Immun (1999) 0.99
Biodegradable microparticles for oral immunization. Vaccine (1993) 0.99
Major histocompatibility complex class I-associated vaccine protection from simian immunodeficiency virus-infected peripheral blood cells. J Exp Med (1994) 0.98
Effect of proteasome inhibitors on monocytic IkappaB-alpha and -beta depletion, NF-kappaB activation, and cytokine production. J Leukoc Biol (1998) 0.98
Both human SP-A1 and Sp-A2 genes are expressed in small and large intestine. Pediatr Pathol Mol Med (2001) 0.98
Right ventricular electrode lead implantation via a persistent left superior vena cava. An improved technique. Angiology (1997) 0.97
Placebo controlled trial of xamoterol versus digoxin in chronic atrial fibrillation. Br Heart J (1990) 0.97
Abnormal monoclonal antibody-defined helper/suppressor T-cell subpopulations in multiple myeloma: relationship to treatment and clinical stage. Br J Haematol (1983) 0.97
Up-regulation of beta-chemokines and down-modulation of CCR5 co-receptors inhibit simian immunodeficiency virus transmission in non-human primates. Immunology (2000) 0.97
The role of gammadelta T cells in generating antiviral factors and beta-chemokines in protection against mucosal simian immunodeficiency virus infection. Eur J Immunol (2000) 0.96
The effect of route of immunization on mucosal immunity and protection. J Infect Dis (1999) 0.96
Comparison of early plasma RNA loads in different macaque species and the impact of different routes of exposure on SIV/SHIV infection. J Med Primatol (2001) 0.96
Immune effector mechanism in parasitic infections. Immunol Lett (1999) 0.95
Immunization with a soluble recombinant HIV protein entrapped in biodegradable microparticles induces HIV-specific CD8+ cytotoxic T lymphocytes and CD4+ Th1 cells. Vaccine (1995) 0.95
Magnolol attenuates peroxidative damage and improves survival of rats with sepsis. Shock (2000) 0.94
Vaccine-induced CD4+ T cells against the simian immunodeficiency virus gag protein. Epitope specificity and relevance to protective immunity. J Immunol (1991) 0.94