Published in J Neurosci on September 30, 2009
Activation and regulation of purinergic P2X receptor channels. Pharmacol Rev (2011) 2.14
Allosteric modulation of ATP-gated P2X receptor channels. Rev Neurosci (2011) 1.16
A putative extracellular salt bridge at the subunit interface contributes to the ion channel function of the ATP-gated P2X2 receptor. J Biol Chem (2010) 1.09
Sensing pulmonary oxidative stress by lung vagal afferents. Respir Physiol Neurobiol (2011) 0.93
Topical application of PPADS inhibits complement activation and choroidal neovascularization in a model of age-related macular degeneration. PLoS One (2013) 0.86
Regulation of ATP-gated P2X channels: from redox signaling to interactions with other proteins. Antioxid Redox Signal (2013) 0.83
Complex role of zinc in methamphetamine toxicity in vitro. Neuroscience (2010) 0.80
Key sites for P2X receptor function and multimerization: overview of mutagenesis studies on a structural basis. Curr Med Chem (2015) 0.80
P2X(7) receptor in the kidneys of diabetic rats submitted to aerobic training or to N-acetylcysteine supplementation [corrected]. PLoS One (2014) 0.76
Role of reactive oxygen species and TRP channels in the cough reflex. Cell Calcium (2016) 0.76
Mitochondrial superoxide generation enhances P2X7R-mediated loss of cell surface CD62L on naive human CD4+ T lymphocytes. J Immunol (2013) 0.76
An intracellular redox sensor for reactive oxygen species at the M3-M4 linker of GABAA ρ1 receptors. Br J Pharmacol (2014) 0.75
Cyclin-dependent kinase 5 modulates the P2X2a receptor channel gating through phosphorylation of C-terminal threonine 372. Pain (2017) 0.75
Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation. N Engl J Med (2014) 4.00
Incremental Support Vector Learning for Ordinal Regression. IEEE Trans Neural Netw Learn Syst (2014) 2.25
Activation and regulation of purinergic P2X receptor channels. Pharmacol Rev (2011) 2.14
Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT. Blood (2012) 1.63
The P2X7 receptor channel pore dilates under physiological ion conditions. J Gen Physiol (2008) 1.57
P2X7 receptor-deficient mice are susceptible to bone cancer pain. Pain (2011) 1.53
An interaction between BZR1 and DELLAs mediates direct signaling crosstalk between brassinosteroids and gibberellins in Arabidopsis. Sci Signal (2012) 1.38
Dependence of STIM1/Orai1-mediated calcium entry on plasma membrane phosphoinositides. J Biol Chem (2009) 1.36
Structure and mechanism of the uracil transporter UraA. Nature (2011) 1.29
F(ab)'2-mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobulins. Nat Med (2003) 1.28
Hydroxyurea nitrosylates and activates soluble guanylyl cyclase in human erythroid cells. Blood (2007) 1.27
Experimental characterization and mathematical modeling of P2X7 receptor channel gating. J Neurosci (2010) 1.25
The xylanolytic enzyme system from the genus Penicillium. J Biotechnol (2006) 1.25
Materials and optimized designs for human-machine interfaces via epidermal electronics. Adv Mater (2013) 1.24
Molecular determinants of the agonist binding domain of a P2X receptor channel. Mol Pharmacol (2005) 1.23
Participation of the Lys313-Ile333 sequence of the purinergic P2X4 receptor in agonist binding and transduction of signals to the channel gate. J Biol Chem (2006) 1.23
P2Y(1) and P2Y(2) receptors are coupled to the NO/cGMP pathway to vasodilate the rat arterial mesenteric bed. Br J Pharmacol (2002) 1.22
Actin-propelled invasive membrane protrusions promote fusogenic protein engagement during cell-cell fusion. Science (2013) 1.21
Mechanism of spontaneous and receptor-controlled electrical activity in pituitary somatotrophs: experiments and theory. J Neurophysiol (2007) 1.19
Allosteric modulation of ATP-gated P2X receptor channels. Rev Neurosci (2011) 1.16
Formation of a polypseudorotaxane via self-assembly of γ-cyclodextrin with poly(N-isopropylacrylamide). Macromol Rapid Commun (2012) 1.14
Hydroxyurea induces the eNOS-cGMP pathway in endothelial cells. Blood (2006) 1.12
Identification of P2X4 receptor-specific residues contributing to the ivermectin effects on channel deactivation. Biochem Biophys Res Commun (2006) 1.12
Intracellular calcium measurements as a method in studies on activity of purinergic P2X receptor channels. Am J Physiol Cell Physiol (2003) 1.10
Role of aromatic and charged ectodomain residues in the P2X(4) receptor functions. J Neurochem (2007) 1.10
Identification of P2X(4) receptor transmembrane residues contributing to channel gating and interaction with ivermectin. Pflugers Arch (2008) 1.08
Anandamide elicits an acute release of nitric oxide through endothelial TRPV1 receptor activation in the rat arterial mesenteric bed. J Physiol (2005) 1.07
The Elav-like protein HuR exerts translational control of viral internal ribosome entry sites. Virology (2009) 1.05
Dissecting the facilitator and inhibitor allosteric metal sites of the P2X4 receptor channel: critical roles of CYS132 for zinc potentiation and ASP138 for copper inhibition. J Biol Chem (2007) 1.04
Expression and roles of pannexins in ATP release in the pituitary gland. Endocrinology (2011) 1.04
Involvement of WalK (VicK) phosphatase activity in setting WalR (VicR) response regulator phosphorylation level and limiting cross-talk in Streptococcus pneumoniae D39 cells. Mol Microbiol (2012) 1.03
A phase I clinical trial of dendritic cell immunotherapy in HCV-infected individuals. J Hepatol (2010) 1.02
Carboxyl-terminal splicing enhances physical interactions between the cytoplasmic tails of purinergic P2X receptors. Mol Pharmacol (2006) 1.00
Parathyroid hormone and bisphosphonate have opposite effects on stress fracture repair. Bone (2010) 1.00
Differential role of extracellular histidines in copper, zinc, magnesium and proton modulation of the P2X7 purinergic receptor. J Neurochem (2007) 0.99
Differences in potency and efficacy of a series of phenylisopropylamine/phenylethylamine pairs at 5-HT(2A) and 5-HT(2C) receptors. Br J Pharmacol (2002) 0.99
The half-life of the T-cell receptor/peptide-major histocompatibility complex interaction can modulate T-cell activation in response to bacterial challenge. Immunology (2007) 0.98
Galectin-8 binds specific beta1 integrins and induces polarized spreading highlighted by asymmetric lamellipodia in Jurkat T cells. Exp Cell Res (2006) 0.97
Calcium-dependent block of P2X7 receptor channel function is allosteric. J Gen Physiol (2011) 0.97
Contribution of multidrug resistance protein MRP5 in control of cyclic guanosine 5'-monophosphate intracellular signaling in anterior pituitary cells. Endocrinology (2006) 0.97
Histidine 140 plays a key role in the inhibitory modulation of the P2X4 nucleotide receptor by copper but not zinc. J Biol Chem (2003) 0.96
Expression profiling and validation of potential reference genes during Paralichthys olivaceus embryogenesis. Mar Biotechnol (NY) (2008) 0.96
Surface display of IgG Fc on baculovirus vectors enhances binding to antigen-presenting cells and cell lines expressing Fc receptors. Arch Virol (2009) 0.96
An aporphine alkaloid from Nelumbo nucifera as an acetylcholinesterase inhibitor and the primary investigation for structure-activity correlations. Nat Prod Res (2011) 0.95
Liver X receptor agonist TO-901317 upregulates SCD1 expression in renal proximal straight tubule. Am J Physiol Renal Physiol (2005) 0.94
Biomineralization: functions of calmodulin-like protein in the shell formation of pearl oyster. Biochim Biophys Acta (2007) 0.94
Dependence of electrical activity and calcium influx-controlled prolactin release on adenylyl cyclase signaling pathway in pituitary lactotrophs. Mol Endocrinol (2006) 0.94
Enteral omega-3 fatty acid supplementation in adult patients with acute respiratory distress syndrome: a systematic review of randomized controlled trials with meta-analysis and trial sequential analysis. Intensive Care Med (2014) 0.94
NO production and eNOS phosphorylation induced by epinephrine through the activation of beta-adrenoceptors. Am J Physiol Heart Circ Physiol (2009) 0.94
Differential expression of miR-195 in esophageal squamous cell carcinoma and miR-195 expression inhibits tumor cell proliferation and invasion by targeting of Cdc42. FEBS Lett (2013) 0.93
Investigation on subcellular localization of Rice stripe virus in its vector small brown planthopper by electron microscopy. Virol J (2013) 0.93
A novel matrix protein p10 from the nacre of pearl oyster (Pinctada fucata) and its effects on both CaCO3 crystal formation and mineralogenic cells. Mar Biotechnol (NY) (2006) 0.93
Role of nucleotide P2 receptors in calcium signaling and prolactin release in pituitary lactotrophs. J Biol Chem (2003) 0.92
Synaptic clustering of PSD-95 is regulated by c-Abl through tyrosine phosphorylation. J Neurosci (2010) 0.92
Long-life and high-rate Li3V2(PO4)3/C nanosphere cathode materials with three-dimensional continuous electron pathways. Nanoscale (2013) 0.92
A Case of Spontaneous Intracranial Hypotension: The Role of Dynamic CT Myelography and Epidural Blood Patch in Diagnosis and Treatment. Conn Med (2015) 0.92
Release and extracellular metabolism of ATP by ecto-nucleotidase eNTPDase 1-3 in hypothalamic and pituitary cells. Purinergic Signal (2005) 0.92
Identification of ectodomain regions contributing to gating, deactivation, and resensitization of purinergic P2X receptors. J Neurosci (2004) 0.91
Proper regeneration from in vitro cultured Arabidopsis thaliana requires the microRNA-directed action of an auxin response factor. Plant J (2012) 0.91
Heteromultimerization modulates P2X receptor functions through participating extracellular and C-terminal subdomains. J Biol Chem (2002) 0.91
The dynamic changes of DNA methylation and histone modifications of salt responsive transcription factor genes in soybean. PLoS One (2012) 0.91
Purinergic P2X(2) receptor desensitization depends on coupling between ectodomain and C-terminal domain. Mol Pharmacol (2002) 0.91
Dependence of multidrug resistance protein-mediated cyclic nucleotide efflux on the background sodium conductance. Mol Pharmacol (2009) 0.91
Two open states of P2X receptor channels. Front Cell Neurosci (2013) 0.91
Steroidal alkaloids from Holarrhena antidysenterica as acetylcholinesterase inhibitors and the investigation for structure-activity relationships. Life Sci (2012) 0.90
A2B adenosine receptor mediates human chorionic vasoconstriction and signals through arachidonic acid cascade. Am J Physiol Heart Circ Physiol (2005) 0.90
Molecular, pharmacological and functional properties of GABA(A) receptors in anterior pituitary cells. J Physiol (2008) 0.90
Role of nonselective cation channels in spontaneous and protein kinase A-stimulated calcium signaling in pituitary cells. Am J Physiol Endocrinol Metab (2011) 0.90
Smac: Its role in apoptosis induction and use in lung cancer diagnosis and treatment. Cancer Lett (2012) 0.89
Functional relevance of aromatic residues in the first transmembrane domain of P2X receptors. J Neurochem (2009) 0.89
Extracellular histidine residues identify common structural determinants in the copper/zinc P2X2 receptor modulation. J Neurochem (2005) 0.89
Dopamine inhibits basal prolactin release in pituitary lactotrophs through pertussis toxin-sensitive and -insensitive signaling pathways. Endocrinology (2007) 0.89
The PI3K pathway drives the maturation of mast cells via microphthalmia transcription factor. Blood (2011) 0.89
Overexpression of Smac promotes Cisplatin-induced apoptosis by activating caspase-3 and caspase-9 in lung cancer A549 cells. Cancer Biother Radiopharm (2012) 0.89
Gating properties of the P2X2a and P2X2b receptor channels: experiments and mathematical modeling. J Gen Physiol (2012) 0.88
The 5'-untranslated region of the mouse mammary tumor virus mRNA exhibits cap-independent translation initiation. Nucleic Acids Res (2009) 0.88
Characterization of purinergic P2X4 receptor channels expressed in anterior pituitary cells. Am J Physiol Endocrinol Metab (2009) 0.88
Down-regulation of intra-hepatic T-cell signaling associated with GB virus C in a HCV/HIV co-infected group with reduced liver disease. J Hepatol (2011) 0.88
P2Y1 and P2Y2 receptor distribution varies along the human placental vascular tree: role of nucleotides in vascular tone regulation. J Physiol (2006) 0.88
In vitro culture and induced differentiation of sheep skeletal muscle satellite cells. Cell Biol Int (2012) 0.88
Clinical application of body diffusion weighted MR imaging in the diagnosis and preoperative N staging of cervical cancer. Chin Med Sci J (2008) 0.87
Serum from aged F344 rats conditions the activation of young macrophages. Mech Ageing Dev (2005) 0.87
A transcriptomic analysis reveals the nature of salinity tolerance of a wheat introgression line. Plant Mol Biol (2011) 0.87
Dual gating mechanism and function of P2X7 receptor channels. Biophys J (2013) 0.86
Composite fibrous membranes of PLGA and chitosan prepared by coelectrospinning and coaxial electrospinning. J Biomed Mater Res A (2010) 0.86
Stoichiometry and conditional stability constants of Cu(II) or Zn(II) clioquinol complexes; implications for Alzheimer's and Huntington's disease therapy. Neurotoxicology (2007) 0.86
Balanced interactions between Lyn, the p85alpha regulatory subunit of class I(A) phosphatidylinositol-3-kinase, and SHIP are essential for mast cell growth and maturation. Mol Cell Biol (2011) 0.86