Published in J Biol Chem on October 25, 2007
Activation and regulation of purinergic P2X receptor channels. Pharmacol Rev (2011) 2.14
Orthosteric and allosteric binding sites of P2X receptors. Eur Biophys J (2008) 1.20
Structural interpretation of P2X receptor mutagenesis studies on drug action. Br J Pharmacol (2010) 1.19
Allosteric modulation of ATP-gated P2X receptor channels. Rev Neurosci (2011) 1.16
Ivermectin antagonizes ethanol inhibition in purinergic P2X4 receptors. J Pharmacol Exp Ther (2010) 1.01
Zinc enhances long-term potentiation through P2X receptor modulation in the hippocampal CA1 region. Eur J Neurosci (2011) 0.96
Opposite effects of zinc on human and rat P2X2 receptors. J Neurosci (2008) 0.92
Heteromeric assembly of P2X subunits. Front Cell Neurosci (2013) 0.90
Positive allosteric modulation by ivermectin of human but not murine P2X7 receptors. Br J Pharmacol (2012) 0.89
Activation of the P2X7 ion channel by soluble and covalently bound ligands. Purinergic Signal (2009) 0.86
Roles of conserved ectodomain cysteines of the rat P2X4 purinoreceptor in agonist binding and channel gating. Physiol Res (2010) 0.86
Structural insights into the function of P2X4: an ATP-gated cation channel of neuroendocrine cells. Cell Mol Neurobiol (2010) 0.85
Allosteric modulation of purine and pyrimidine receptors. Adv Pharmacol (2011) 0.84
Regulation of ATP-gated P2X channels: from redox signaling to interactions with other proteins. Antioxid Redox Signal (2013) 0.83
Conserved ectodomain cysteines are essential for rat P2X7 receptor trafficking. Purinergic Signal (2012) 0.81
Inactivation of TRPM2 channels by extracellular divalent copper. PLoS One (2014) 0.79
Conserved extracellular cysteines differentially regulate the potentiation produced by Zn2+ in rat P2X4 receptors. Eur J Pharmacol (2013) 0.76
Potent and long-lasting inhibition of human P2X2 receptors by copper. Neuropharmacology (2013) 0.75
Copper inhibits P2Y(2)-dependent Ca(2+) signaling through the effects on thapsigargin-sensitive Ca(2+) stores in HTC hepatoma cells. Biochem Biophys Res Commun (2010) 0.75
Zinc as Allosteric Ion Channel Modulator: Ionotropic Receptors as Metalloproteins. Int J Mol Sci (2016) 0.75
P2X4 Receptor Function in the Nervous System and Current Breakthroughs in Pharmacology. Front Pharmacol (2017) 0.75
Activation and regulation of purinergic P2X receptor channels. Pharmacol Rev (2011) 2.14
The xylanolytic enzyme system from the genus Penicillium. J Biotechnol (2006) 1.25
P2Y(1) and P2Y(2) receptors are coupled to the NO/cGMP pathway to vasodilate the rat arterial mesenteric bed. Br J Pharmacol (2002) 1.22
Allosteric modulation of ATP-gated P2X receptor channels. Rev Neurosci (2011) 1.16
Anandamide elicits an acute release of nitric oxide through endothelial TRPV1 receptor activation in the rat arterial mesenteric bed. J Physiol (2005) 1.07
The Elav-like protein HuR exerts translational control of viral internal ribosome entry sites. Virology (2009) 1.05
Differential role of extracellular histidines in copper, zinc, magnesium and proton modulation of the P2X7 purinergic receptor. J Neurochem (2007) 0.99
Differences in potency and efficacy of a series of phenylisopropylamine/phenylethylamine pairs at 5-HT(2A) and 5-HT(2C) receptors. Br J Pharmacol (2002) 0.99
The half-life of the T-cell receptor/peptide-major histocompatibility complex interaction can modulate T-cell activation in response to bacterial challenge. Immunology (2007) 0.98
Galectin-8 binds specific beta1 integrins and induces polarized spreading highlighted by asymmetric lamellipodia in Jurkat T cells. Exp Cell Res (2006) 0.97
Histidine 140 plays a key role in the inhibitory modulation of the P2X4 nucleotide receptor by copper but not zinc. J Biol Chem (2003) 0.96
NO production and eNOS phosphorylation induced by epinephrine through the activation of beta-adrenoceptors. Am J Physiol Heart Circ Physiol (2009) 0.94
Synaptic clustering of PSD-95 is regulated by c-Abl through tyrosine phosphorylation. J Neurosci (2010) 0.92
A2B adenosine receptor mediates human chorionic vasoconstriction and signals through arachidonic acid cascade. Am J Physiol Heart Circ Physiol (2005) 0.90
Extracellular histidine residues identify common structural determinants in the copper/zinc P2X2 receptor modulation. J Neurochem (2005) 0.89
P2Y1 and P2Y2 receptor distribution varies along the human placental vascular tree: role of nucleotides in vascular tone regulation. J Physiol (2006) 0.88
The 5'-untranslated region of the mouse mammary tumor virus mRNA exhibits cap-independent translation initiation. Nucleic Acids Res (2009) 0.88
Reactive oxygen species potentiate the P2X2 receptor activity through intracellular Cys430. J Neurosci (2009) 0.87
Serum from aged F344 rats conditions the activation of young macrophages. Mech Ageing Dev (2005) 0.87
Characterization of an alpha-L-arabinofuranosidase gene (abf1) from Penicillium purpurogenum and its expression. Mycol Res (2003) 0.86
Stoichiometry and conditional stability constants of Cu(II) or Zn(II) clioquinol complexes; implications for Alzheimer's and Huntington's disease therapy. Neurotoxicology (2007) 0.86
Chronic intermittent hypoxia augments sympatho-excitatory response to ATP but not to L-glutamate in the RVLM of rats. Auton Neurosci (2011) 0.85
Oxidative damage in lymphocytes of copper smelter workers correlated to higher levels of excreted arsenic. Mediators Inflamm (2010) 0.85
Heavy metals modulate the activity of the purinergic P2X4 receptor. Toxicol Appl Pharmacol (2005) 0.84
Differences in expression of two endoxylanase genes (xynA and xynB) from Penicillium purpurogenum. Gene (2002) 0.82
The hypolipidemic drug metabolites nafenopin-CoA and ciprofibroyl-CoA are competitive P2Y1 receptor antagonists. FEBS Lett (2003) 0.82
The role of adenosine A2A and A3 receptors on the differential modulation of norepinephrine and neuropeptide Y release from peripheral sympathetic nerve terminals. J Neurochem (2006) 0.82
4-Bromo-2,5-dimethoxyphenethylamine (2C-B) and structurally related phenylethylamines are potent 5-HT2A receptor antagonists in Xenopus laevis oocytes. Br J Pharmacol (2004) 0.82
Penicillium purpurogenum produces a family 1 acetyl xylan esterase containing a carbohydrate-binding module: characterization of the protein and its gene. Mycol Res (2006) 0.81
UTP controls cell surface distribution and vasomotor activity of the human P2Y2 receptor through an epidermal growth factor receptor-transregulated mechanism. J Biol Chem (2009) 0.81
Neisseria gonorrhoeae induces a tolerogenic phenotype in macrophages to modulate host immunity. Mediators Inflamm (2013) 0.81
Lipopolysaccharide signaling in the carotid chemoreceptor pathway of rats with sepsis syndrome. Respir Physiol Neurobiol (2010) 0.81
The release of sympathetic neurotransmitters is impaired in aged rats after an inflammatory stimulus: a possible link between cytokine production and sympathetic transmission. Mech Ageing Dev (2008) 0.80
Polymyxin B increases the depletion of T regulatory cell induced by purinergic agonist. Immunobiology (2011) 0.80
A cis-acting element present within the Gag open reading frame negatively impacts on the activity of the HIV-1 IRES. PLoS One (2013) 0.80
Secretion of endoxylanase A from Penicillium purpurogenum by Saccharomyces cerevisiae transformed with genomic fungal DNA. FEMS Microbiol Lett (2002) 0.80
alpha2-Adrenoceptors control the release of noradrenaline but not neuropeptide Y from perivascular nerve terminals. Peptides (2002) 0.78
Neuromodulator role of zinc and copper during prolonged ATP applications to P2X4 purinoceptors. Eur J Pharmacol (2003) 0.78
Diminished acute phase response and increased hepatic inflammation of aged rats in response to intraperitoneal injection of lipopolysaccharide. J Gerontol A Biol Sci Med Sci (2008) 0.78
Neuropeptide Y is released from human mammary and radial vascular biopsies and is a functional modulator of sympathetic cotransmission. J Vasc Res (2004) 0.78
Functional analysis of the endoxylanase B (xynB) promoter from Penicillium purpurogenum. Curr Genet (2008) 0.78
Lipopolysaccharide inhibits the channel activity of the P2X7 receptor. Mediators Inflamm (2011) 0.77
The copper-dependent ACE1 transcription factor activates the transcription of the mco1 gene from the basidiomycete Phanerochaete chrysosporium. Microbiology (2008) 0.77
Defect in ERK2 and p54(JNK) activation in aging mouse splenocytes. J Gerontol A Biol Sci Med Sci (2002) 0.77
Release and functional role of neuropeptide Y as a sympathetic modulator in human saphenous vein biopsies. Peptides (2004) 0.76
The human prion octarepeat fragment prevents and reverses the inhibitory action of copper in the P2X4 receptor without modifying the zinc action. J Neurochem (2003) 0.76
T-kininogen induces endothelial cell proliferation. Mech Ageing Dev (2005) 0.76
Formation of carnosine-Cu(II) complexes prevents and reverts the inhibitory action of copper in P2X4 and P2X7 receptors. J Neurochem (2002) 0.76
Increased kinin levels and decreased responsiveness to kinins during aging. J Gerontol A Biol Sci Med Sci (2005) 0.76
P2Y1 receptor activation elicits its partition out of membrane rafts and its rapid internalization from human blood vessels: implications for receptor signaling. Mol Pharmacol (2008) 0.76
Modulator role of neuropeptide Y in human vascular sympathetic neuroeffector junctions. EXS (2006) 0.75
The Cellular Prion Protein Prevents Copper-Induced Inhibition of P2X(4) Receptors. Int J Alzheimers Dis (2011) 0.75
T-kininogen inhibits kinin-mediated activation of ERK in endothelial cells. Biol Res (2002) 0.75
The PcACE1 transcription factor from Phanerochaete chrysosporium contains a Cys- and Ser-rich transactivation domain. Biol Res (2012) 0.75
The acetyl xylan esterase II gene from Penicillium purpurogenum is differentially expressed in several carbon sources, and tightly regulated by pH. Biol Res (2004) 0.75