Published in Neoplasia on October 01, 2009
CXCL12 / CXCR4 / CXCR7 chemokine axis and cancer progression. Cancer Metastasis Rev (2010) 3.24
Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7. Proc Natl Acad Sci U S A (2009) 2.76
CXCR7/CXCR4 heterodimer constitutively recruits beta-arrestin to enhance cell migration. J Biol Chem (2011) 1.78
Constitutive and chemokine-dependent internalization and recycling of CXCR7 in breast cancer cells to degrade chemokine ligands. Oncogene (2010) 1.69
In vivo imaging of ligand receptor binding with Gaussia luciferase complementation. Nat Med (2011) 1.35
Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis. Breast Cancer Res (2011) 1.33
Immune regulation by atypical chemokine receptors. Nat Rev Immunol (2013) 1.17
Noninvasive imaging reveals inhibition of ovarian cancer by targeting CXCL12-CXCR4. Neoplasia (2011) 1.00
Ubiquitination of CXCR7 controls receptor trafficking. PLoS One (2012) 1.00
CXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment. Front Cell Neurosci (2014) 0.96
CXCR7 protein expression in human adult brain and differentiated neurons. PLoS One (2011) 0.96
Secreted CXCL12 (SDF-1) forms dimers under physiological conditions. Biochem J (2012) 0.95
CXCL12-induced monocyte-endothelial interactions promote lymphocyte transmigration across an in vitro blood-brain barrier. Sci Transl Med (2012) 0.95
NanoLuc reporter for dual luciferase imaging in living animals. Mol Imaging (2013) 0.93
CXCL12 enhances human neural progenitor cell survival through a CXCR7- and CXCR4-mediated endocytotic signaling pathway. Stem Cells (2012) 0.93
The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation. Mol Cancer (2014) 0.92
Endothelial expression of CXCR7 and the regulation of systemic CXCL12 levels. Immunology (2014) 0.90
CXCR7 controls competition for recruitment of β-arrestin 2 in cells expressing both CXCR4 and CXCR7. PLoS One (2014) 0.90
C-X-C motif chemokine 12/C-X-C chemokine receptor type 7 signaling regulates breast cancer growth and metastasis by modulating the tumor microenvironment. Breast Cancer Res (2014) 0.90
Carboxy-terminus of CXCR7 regulates receptor localization and function. Int J Biochem Cell Biol (2012) 0.89
Llama-derived single variable domains (nanobodies) directed against chemokine receptor CXCR7 reduce head and neck cancer cell growth in vivo. J Biol Chem (2013) 0.88
CXCL12-γ in primary tumors drives breast cancer metastasis. Oncogene (2014) 0.84
Microfluidic source-sink model reveals effects of biophysically distinct CXCL12 isoforms in breast cancer chemotaxis. Integr Biol (Camb) (2014) 0.84
Cell-based and in vivo spectral analysis of fluorescent proteins for multiphoton microscopy. J Biomed Opt (2012) 0.83
CXC chemokine receptor 7 (CXCR7) affects the migration of GnRH neurons by regulating CXCL12 availability. J Neurosci (2013) 0.83
CXCR7 stimulates MAPK signaling to regulate hepatocellular carcinoma progression. Cell Death Dis (2014) 0.82
CXC chemokine receptor 7 (CXCR7) regulates CXCR4 protein expression and capillary tuft development in mouse kidney. PLoS One (2012) 0.82
Grk2 is an essential regulator of CXCR7 signalling in astrocytes. Cell Mol Neurobiol (2012) 0.81
G Protein Coupled Receptor Kinase 3 Regulates Breast Cancer Migration, Invasion, and Metastasis. PLoS One (2016) 0.80
Multiplexed spectral signature detection for microfluidic color-coded bioparticle flow. Anal Chem (2010) 0.80
Dynamic analysis of GH receptor conformational changes by split luciferase complementation. Mol Endocrinol (2014) 0.78
Androgen receptor and chemokine receptors 4 and 7 form a signaling axis to regulate CXCL12-dependent cellular motility. BMC Cancer (2015) 0.77
A Preclinical Model of Inflammatory Breast Cancer to Study the Involvement of CXCR4 and ACKR3 in the Metastatic Process. Transl Oncol (2015) 0.77
A Broad G Protein-Coupled Receptor Internalization Assay that Combines SNAP-Tag Labeling, Diffusion-Enhanced Resonance Energy Transfer, and a Highly Emissive Terbium Cryptate. Front Endocrinol (Lausanne) (2015) 0.77
Muscarinic acetylcholine receptor M3 modulates odorant receptor activity via inhibition of β-arrestin-2 recruitment. Nat Commun (2015) 0.77
Allosteric peptide regulators of chemokine receptors CXCR4 and CXCR7. Biochem Pharmacol (2013) 0.76
Mechanisms of immunomodulation by mammalian and viral decoy receptors: insights from structures. Nat Rev Immunol (2016) 0.76
Homing in hematopoietic stem cells: focus on regulatory role of CXCR7 on SDF1a/CXCR4 axis. EXCLI J (2016) 0.76
Luciferase fragment complementation imaging in preclinical cancer studies. Oncoscience (2014) 0.76
Targeted Imaging of the Atypical Chemokine Receptor 3 (ACKR3/CXCR7) in Human Cancer Xenografts. J Nucl Med (2016) 0.76
The War on Cancer rages on. Neoplasia (2009) 0.75
The interconnectedness of cancer cell signaling. Neoplasia (2011) 0.75
Mutational Analysis of Atypical Chemokine Receptor 3 (ACKR3/CXCR7) Interaction with its Chemokine Ligands CXCL11 and CXCL12. J Biol Chem (2016) 0.75
Dinosaurs and ancient civilizations: reflections on the treatment of cancer. Neoplasia (2010) 0.75
Emerging Targets in Pituitary Adenomas: Role of the CXCL12/CXCR4-R7 System. Int J Endocrinol (2014) 0.75
Biological/pathological functions of the CXCL12/CXCR4/CXCR7 axes in the pathogenesis of bladder cancer. Int J Clin Oncol (2017) 0.75
Involvement of chemokine receptors in breast cancer metastasis. Nature (2001) 26.07
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell (2005) 18.20
Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science (2002) 17.71
Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature (1998) 11.41
Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature (1996) 10.67
Reducing the environmental sensitivity of yellow fluorescent protein. Mechanism and applications. J Biol Chem (2001) 9.27
Beta-arrestins and cell signaling. Annu Rev Physiol (2007) 8.65
The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature (1998) 7.38
A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development. J Exp Med (2006) 6.86
Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. Mol Ther (2005) 6.04
The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes. J Biol Chem (2005) 5.45
Control of chemokine-guided cell migration by ligand sequestration. Cell (2008) 4.61
CXCR4 regulates growth of both primary and metastatic breast cancer. Cancer Res (2004) 4.53
Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors. J Biol Chem (2000) 4.46
Regulation of receptor trafficking by GRKs and arrestins. Annu Rev Physiol (2007) 4.17
CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature. Proc Natl Acad Sci U S A (2007) 3.85
Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci U S A (2007) 3.61
Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animals. Proc Natl Acad Sci U S A (2004) 3.59
The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer. J Biol Chem (2007) 3.38
Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins. Prog Neurobiol (2002) 2.76
The chemokine SDF1a coordinates tissue migration through the spatially restricted activation of Cxcr7 and Cxcr4b. Curr Biol (2007) 2.35
Stromal cell-derived factor-1alpha associates with heparan sulfates through the first beta-strand of the chemokine. J Biol Chem (1999) 2.32
Noninvasive bioluminescence imaging of herpes simplex virus type 1 infection and therapy in living mice. J Virol (2002) 2.31
Essential but differential role for CXCR4 and CXCR7 in the therapeutic homing of human renal progenitor cells. J Exp Med (2008) 2.25
Control of cell migration in the development of the posterior lateral line: antagonistic interactions between the chemokine receptors CXCR4 and CXCR7/RDC1. BMC Dev Biol (2007) 2.24
Bioluminescence resonance energy transfer reveals ligand-induced conformational changes in CXCR4 homo- and heterodimers. J Biol Chem (2005) 2.10
The chemokine receptor CCX-CKR mediates effective scavenging of CCL19 in vitro. Eur J Immunol (2006) 2.09
Stromal cell-derived factor 1, a novel target of estrogen receptor action, mediates the mitogenic effects of estradiol in ovarian and breast cancer cells. Mol Endocrinol (2003) 2.03
AMD3100 is a CXCR7 ligand with allosteric agonist properties. Mol Pharmacol (2009) 1.99
A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells. J Leukoc Biol (2008) 1.87
Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases. Nature (1992) 1.81
beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4. J Biol Chem (2000) 1.67
Glioma tropic neural stem cells consist of astrocytic precursors and their migratory capacity is mediated by CXCR4. Neoplasia (2004) 1.56
SLITs suppress tumor growth in vivo by silencing Sdf1/Cxcr4 within breast epithelium. Cancer Res (2008) 1.52
CXCR4 chemokine receptor mediates prostate tumor cell adhesion through alpha5 and beta3 integrins. Neoplasia (2006) 1.52
Synergistic regulation of beta2-adrenergic receptor sequestration: intracellular complement of beta-adrenergic receptor kinase and beta-arrestin determine kinetics of internalization. Mol Pharmacol (1997) 1.51
In vivo phage display selection yields atherosclerotic plaque targeted peptides for imaging. Mol Imaging Biol (2006) 1.51
CXCR3 expression is associated with poor survival in breast cancer and promotes metastasis in a murine model. Mol Cancer Ther (2009) 1.43
Imaging chemokine receptor dimerization with firefly luciferase complementation. FASEB J (2008) 1.42
beta-Arrestin-dependent constitutive internalization of the human chemokine decoy receptor D6. J Biol Chem (2004) 1.39
Differential functional activation of chemokine receptor CXCR4 is mediated by G proteins in breast cancer cells. Cancer Res (2006) 1.35
Expression and regulation of the orphan receptor RDC1 and its putative ligand in human dendritic and B cells. J Immunol (2006) 1.33
Bioluminescent CXCL12 fusion protein for cellular studies of CXCR4 and CXCR7. Biotechniques (2009) 1.32
Imaging CXCR4 signaling with firefly luciferase complementation. Anal Chem (2008) 1.32
Differential beta-arrestin trafficking and endosomal sorting of somatostatin receptor subtypes. J Biol Chem (2004) 1.32
CD24 affects CXCR4 function in pre-B lymphocytes and breast carcinoma cells. J Cell Sci (2006) 1.30
Enhanced expression of the CXCl12/SDF-1 chemokine receptor CXCR7 after cerebral ischemia in the rat brain. J Neuroimmunol (2008) 1.27
Stromal cell-derived factor-1 promotes cell migration and tumor growth of colorectal metastasis. Neoplasia (2007) 1.25
Zerumbone down-regulates chemokine receptor CXCR4 expression leading to inhibition of CXCL12-induced invasion of breast and pancreatic tumor cells. Cancer Res (2008) 1.18
The duffy antigen/receptor for chemokines exists in an oligomeric form in living cells and functionally antagonizes CCR5 signaling through hetero-oligomerization. Mol Pharmacol (2008) 1.14
Tissue microenvironment modulates CXCR4 expression and tumor metastasis in neuroblastoma. Neoplasia (2007) 1.08
Synthesis and application of fluorescein- and biotin-labeled molecular probes for the chemokine receptor CXCR4. Chembiochem (2008) 1.04
UNBS5162, a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers. Neoplasia (2008) 0.99
Effects of multidrug resistance (MDR1) P-glycoprotein expression levels and coordination metal on the cytotoxic potency of multidentate (N4O2) (ethylenediamine)bis[propyl(R-benzylimino)]metal(III) cations. J Med Chem (1996) 0.89
Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell (2011) 6.11
CXCR4 regulates growth of both primary and metastatic breast cancer. Cancer Res (2004) 4.53
Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9. Blood (2003) 3.98
CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature. Proc Natl Acad Sci U S A (2007) 3.85
Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animals. Proc Natl Acad Sci U S A (2004) 3.59
Near-infrared fluorescent proteins. Nat Methods (2010) 2.52
Applications of bioluminescence imaging to the study of infectious diseases. Cell Microbiol (2007) 2.31
Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy. J Control Release (2012) 2.12
Functions of CXCL12 and CXCR4 in breast cancer. Cancer Lett (2005) 2.11
Bioluminescence imaging of vaccinia virus: effects of interferon on viral replication and spread. Virology (2005) 1.89
Microfluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cells. PLoS One (2009) 1.87
CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity. J Exp Med (2011) 1.82
Imaging chemokine receptor dimerization with firefly luciferase complementation. FASEB J (2008) 1.42
In vivo imaging of ligand receptor binding with Gaussia luciferase complementation. Nat Med (2011) 1.35
Microfluidic hydrodynamic cellular patterning for systematic formation of co-culture spheroids. Integr Biol (Camb) (2009) 1.33
Imaging CXCR4 signaling with firefly luciferase complementation. Anal Chem (2008) 1.32
Bioluminescent CXCL12 fusion protein for cellular studies of CXCR4 and CXCR7. Biotechniques (2009) 1.32
TLR3 increases disease morbidity and mortality from vaccinia infection. J Immunol (2008) 1.26
Molecular imaging of gene expression and protein function in vivo with PET and SPECT. J Magn Reson Imaging (2002) 1.21
Applications of bioluminescence imaging to antiviral research and therapy: multiple luciferase enzymes and quantitation. Antiviral Res (2008) 1.18
Microfluidic platform for chemotaxis in gradients formed by CXCL12 source-sink cells. Integr Biol (Camb) (2010) 1.17
Monitoring serial changes in circulating human breast cancer cells in murine xenograft models. Cancer Res (2008) 1.09
Vaccinia virus infection induces dendritic cell maturation but inhibits antigen presentation by MHC class II. Cell Immunol (2007) 1.05
Generation of a highly inducible Gal4-->Fluc universal reporter mouse for in vivo bioluminescence imaging. Proc Natl Acad Sci U S A (2008) 1.04
A novel, killed-virus nasal vaccinia virus vaccine. Clin Vaccine Immunol (2007) 1.03
Murine alveolar macrophages limit replication of vaccinia virus. Virology (2007) 1.02
In Vivo Monitoring of Multiple Circulating Cell Populations Using Two-photon Flow Cytometry. Opt Commun (2008) 1.02
Protective effect of Toll-like receptor 4 in pulmonary vaccinia infection. PLoS Pathog (2008) 1.02
Noninvasive imaging reveals inhibition of ovarian cancer by targeting CXCL12-CXCR4. Neoplasia (2011) 1.00
Type I interferon regulates respiratory virus infected dendritic cell maturation and cytokine production. Viral Immunol (2007) 1.00
Prodromal herpes zoster mimicking odontalgia--a diagnostic challenge. Ethiop J Health Sci (2013) 0.98
Altered excitation-inhibition balance in the brain of patients with diabetic neuropathy. Acad Radiol (2012) 0.97
Secreted CXCL12 (SDF-1) forms dimers under physiological conditions. Biochem J (2012) 0.95
Bioluminescence imaging of reporter mice for studies of infection and inflammation. Antiviral Res (2010) 0.95
Transgenic reporter mouse for bioluminescence imaging of herpes simplex virus 1 infection in living mice. Virology (2006) 0.93
NanoLuc reporter for dual luciferase imaging in living animals. Mol Imaging (2013) 0.93
The utility of independent component analysis and machine learning in the identification of the amyotrophic lateral sclerosis diseased brain. Front Hum Neurosci (2013) 0.93
Anomalous systemic artery to a normal lung: a rare cause of hemoptysis in adults. Oman Med J (2012) 0.90
Polymeric Aqueous Biphasic System Rehydration Facilitates High Throughput Cell Exclusion Patterning For Cell Migration Studies. Adv Funct Mater (2011) 0.89
Excitatory and inhibitory brain metabolites as targets of motor cortex transcranial direct current stimulation therapy and predictors of its efficacy in fibromyalgia. Arthritis Rheumatol (2015) 0.89
Carboxy-terminus of CXCR7 regulates receptor localization and function. Int J Biochem Cell Biol (2012) 0.89
Imaging CXCL12-CXCR4 signaling in ovarian cancer therapy. PLoS One (2013) 0.88
Targeted non-covalent self-assembled nanoparticles based on human serum albumin. Biomaterials (2011) 0.88
Advancing the translation of optical imaging agents for clinical imaging. Biomed Opt Express (2012) 0.86
Decreased cell adhesion promotes angiogenesis in a Pyk2-dependent manner. Exp Cell Res (2011) 0.86
Murine craniofacial development requires Hdac3-mediated repression of Msx gene expression. Dev Biol (2013) 0.84
Synthesis and investigation of a radioiodinated F3 peptide analog as a SPECT tumor imaging radioligand. PLoS One (2011) 0.84
Translational research in radiology: challenges and role in a patient-based practice. Acad Radiol (2009) 0.83
Extended cavity laser enhanced two-photon flow cytometry. J Biomed Opt (2008) 0.83
Neuroimaging as a New Diagnostic Modality in Amyotrophic Lateral Sclerosis. Neurotherapeutics (2015) 0.83
Cell-based and in vivo spectral analysis of fluorescent proteins for multiphoton microscopy. J Biomed Opt (2012) 0.83
Transfer, imaging, and analysis plate for facile handling of 384 hanging drop 3D tissue spheroids. J Lab Autom (2013) 0.82
Applications of molecular imaging. Prog Mol Biol Transl Sci (2010) 0.81
Imaging pulmonary gene expression with positron emission tomography. Am J Respir Crit Care Med (2002) 0.81
Multiplexed spectral signature detection for microfluidic color-coded bioparticle flow. Anal Chem (2010) 0.80
Gas gangrene in the abdominal wall: a physician's nightmare. Clin Res Hepatol Gastroenterol (2013) 0.80
Real-time bioluminescence imaging of viral pathogenesis. Methods Mol Biol (2009) 0.79
Longitudinal molecular imaging with single cell resolution of disseminated ovarian cancer in mice with a LED-based confocal microendoscope. Mol Imaging Biol (2011) 0.79
Macrocerebellum, epilepsy, intellectual disability, and gut malrotation in a child with a 16q24.1-q24.2 contiguous gene deletion. Am J Med Genet A (2014) 0.78
Relative roles of magnetic resonance angiography and computed tomographic angiography in evaluation of symptomatic carotid stenosis: a critically appraised topic. Semin Roentgenol (2009) 0.77
Phytochemicals potently inhibit migration of metastatic breast cancer cells. Integr Biol (Camb) (2015) 0.76
CXCR4-Targeted Nanocarriers for Triple Negative Breast Cancers. Biomacromolecules (2015) 0.76
Allosteric peptide regulators of chemokine receptors CXCR4 and CXCR7. Biochem Pharmacol (2013) 0.76
Vision Loss After Central Retinal Artery Occlusion Secondary to Orbital Sarcoid Mass. Ophthal Plast Reconstr Surg (2016) 0.76
Split Gaussia luciferase for imaging ligand-receptor binding. Methods Mol Biol (2014) 0.75
Imaging Reporters for Proteasome Activity Identify Tumor- and Metastasis-Initiating Cells. Mol Imaging (2015) 0.75
Correction: Cell, Isoform, and Environment Factors Shape Gradients and Modulate Chemotaxis. PLoS One (2017) 0.75
Hypercreatinemia: think beyond acute kidney injury. Can J Urol (2011) 0.75
Evolving pneumopericardium. Heart (2007) 0.75
2021 Manuscript Reviewers: A Note of Thanks. Radiol Imaging Cancer (2022) 0.75
Evolving pneumopericardium. BMJ Case Rep (2009) 0.75
Editor's Recognition Awards. Radiol Imaging Cancer (2022) 0.75
Acute graft-versus-host disease of bowel. Clin Gastroenterol Hepatol (2012) 0.75
Dispersible oxygen microsensors map oxygen gradients in three-dimensional cell cultures. Biomater Sci (2017) 0.75
MRI features of oriental cholangiohepatitis. Clin Res Hepatol Gastroenterol (2012) 0.75