Published in Virology on August 10, 2005
Targeted and armed oncolytic poxviruses: a novel multi-mechanistic therapeutic class for cancer. Nat Rev Cancer (2009) 3.06
Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963. J Clin Invest (2007) 2.36
Targeting of interferon-beta to produce a specific, multi-mechanistic oncolytic vaccinia virus. PLoS Med (2007) 2.15
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The oncolytic poxvirus JX-594 selectively replicates in and destroys cancer cells driven by genetic pathways commonly activated in cancers. Mol Ther (2011) 1.59
In vivo bioluminescent imaging of influenza a virus infection and characterization of novel cross-protective monoclonal antibodies. J Virol (2013) 1.59
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TLR3 increases disease morbidity and mortality from vaccinia infection. J Immunol (2008) 1.26
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Adjuvant-enhanced antibody responses to recombinant proteins correlates with protection of mice and monkeys to orthopoxvirus challenges. Vaccine (2007) 1.21
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Applications of bioluminescence imaging to antiviral research and therapy: multiple luciferase enzymes and quantitation. Antiviral Res (2008) 1.18
Targeting localized immune suppression within the tumor through repeat cycles of immune cell-oncolytic virus combination therapy. Mol Ther (2010) 1.15
ST-246 inhibits in vivo poxvirus dissemination, virus shedding, and systemic disease manifestation. Antimicrob Agents Chemother (2009) 1.07
Vaccinia virus infection induces dendritic cell maturation but inhibits antigen presentation by MHC class II. Cell Immunol (2007) 1.05
Roles of vaccinia virus genes E3L and K3L and host genes PKR and RNase L during intratracheal infection of C57BL/6 mice. J Virol (2010) 1.04
A novel, killed-virus nasal vaccinia virus vaccine. Clin Vaccine Immunol (2007) 1.03
Lister strain of vaccinia virus armed with endostatin-angiostatin fusion gene as a novel therapeutic agent for human pancreatic cancer. Gene Ther (2009) 1.02
Murine alveolar macrophages limit replication of vaccinia virus. Virology (2007) 1.02
Protective effect of Toll-like receptor 4 in pulmonary vaccinia infection. PLoS Pathog (2008) 1.02
Disparity between levels of in vitro neutralization of vaccinia virus by antibody to the A27 protein and protection of mice against intranasal challenge. J Virol (2008) 1.01
Application of bioluminescence imaging to the prediction of lethality in vaccinia virus-infected mice. J Virol (2009) 1.00
Alternate mechanisms of initial pattern recognition drive differential immune responses to related poxviruses. Cell Host Microbe (2010) 0.97
Bioluminescence imaging of reporter mice for studies of infection and inflammation. Antiviral Res (2010) 0.95
Development of a baited oral vaccine for use in reservoir-targeted strategies against Lyme disease. Vaccine (2011) 0.94
CD8 T cells are essential for recovery from a respiratory vaccinia virus infection. J Immunol (2012) 0.93
Vaccinia virus entry, exit, and interaction with differentiated human airway epithelia. J Virol (2007) 0.89
Susceptibility of the wild-derived inbred CAST/Ei mouse to infection by orthopoxviruses analyzed by live bioluminescence imaging. Virology (2013) 0.88
Vaccinia virus encodes I5, a small hydrophobic virion membrane protein that enhances replication and virulence in mice. J Virol (2008) 0.87
Comparative live bioluminescence imaging of monkeypox virus dissemination in a wild-derived inbred mouse (Mus musculus castaneus) and outbred African dormouse (Graphiurus kelleni). Virology (2014) 0.85
A selectable and excisable marker system for the rapid creation of recombinant poxviruses. PLoS One (2011) 0.82
A marker-free system for highly efficient construction of vaccinia virus vectors using CRISPR Cas9. Mol Ther Methods Clin Dev (2015) 0.82
Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination. Proc Natl Acad Sci U S A (2016) 0.81
Molecular imaging of influenza and other emerging respiratory viral infections. J Infect Dis (2011) 0.80
Real-time bioluminescence imaging of viral pathogenesis. Methods Mol Biol (2009) 0.79
Vaccinia virus, a promising new therapeutic agent for pancreatic cancer. Immunotherapy (2015) 0.78
Bioluminescent imaging of vaccinia virus infection in immunocompetent and immunodeficient rats as a model for human smallpox. Sci Rep (2015) 0.77
Fiat Luc: Bioluminescence Imaging Reveals In Vivo Viral Replication Dynamics. PLoS Pathog (2015) 0.76
A bright future for bioluminescent imaging in viral research. Future Virol (2015) 0.76
Effects of postchallenge administration of ST-246 on dissemination of IHD-J-Luc vaccinia virus in normal mice and in immune-deficient mice reconstituted with T cells. J Virol (2013) 0.76
Visualization of a neurotropic flavivirus infection in mouse reveals unique viscerotropism controlled by host type I interferon signaling. Theranostics (2017) 0.75
Insufficient Innate Immunity Contributes to the Susceptibility of the Castaneous Mouse to Orthopoxvirus Infection. J Virol (2017) 0.75
CXCR4 regulates growth of both primary and metastatic breast cancer. Cancer Res (2004) 4.53
IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses. Proc Natl Acad Sci U S A (2007) 3.98
Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9. Blood (2003) 3.98
CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature. Proc Natl Acad Sci U S A (2007) 3.85
Influenza virus receptor specificity and cell tropism in mouse and human airway epithelial cells. J Virol (2006) 3.60
Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animals. Proc Natl Acad Sci U S A (2004) 3.59
Influenza a virus M2 ion channel activity is essential for efficient replication in tissue culture. J Virol (2002) 2.97
The Xs and Y of immune responses to viral vaccines. Lancet Infect Dis (2010) 2.54
Near-infrared fluorescent proteins. Nat Methods (2010) 2.52
Applications of bioluminescence imaging to the study of infectious diseases. Cell Microbiol (2007) 2.31
The influenza A virus M2 cytoplasmic tail is required for infectious virus production and efficient genome packaging. J Virol (2005) 2.23
Distinct domains of the influenza a virus M2 protein cytoplasmic tail mediate binding to the M1 protein and facilitate infectious virus production. J Virol (2006) 2.18
Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy. J Control Release (2012) 2.12
Functions of CXCL12 and CXCR4 in breast cancer. Cancer Lett (2005) 2.11
Microfluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cells. PLoS One (2009) 1.87
CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity. J Exp Med (2011) 1.82
Virus-inducible reporter genes as a tool for detecting and quantifying influenza A virus replication. J Virol Methods (2005) 1.62
Dendritic cells respond to influenza virus through TLR7- and PKR-independent pathways. Eur J Immunol (2005) 1.62
Interferon-producing cells fail to induce proliferation of naive T cells but can promote expansion and T helper 1 differentiation of antigen-experienced unpolarized T cells. J Exp Med (2003) 1.54
No evidence of infection with avian influenza viruses among US poultry workers in the Delmarva Peninsula, Maryland and Virginia, USA. J Agromedicine (2011) 1.47
Imaging ligand-dependent activation of CXCR7. Neoplasia (2009) 1.43
Imaging chemokine receptor dimerization with firefly luciferase complementation. FASEB J (2008) 1.42
Human antibodies reveal a protective epitope that is highly conserved among human and nonhuman influenza A viruses. Proc Natl Acad Sci U S A (2010) 1.42
Influenza virus-like particles containing M2 induce broadly cross protective immunity. PLoS One (2011) 1.40
In vivo imaging of ligand receptor binding with Gaussia luciferase complementation. Nat Med (2011) 1.35
Microfluidic hydrodynamic cellular patterning for systematic formation of co-culture spheroids. Integr Biol (Camb) (2009) 1.33
Imaging CXCR4 signaling with firefly luciferase complementation. Anal Chem (2008) 1.32
TLR3 increases disease morbidity and mortality from vaccinia infection. J Immunol (2008) 1.26
The utility of siRNA transcripts produced by RNA polymerase i in down regulating viral gene expression and replication of negative- and positive-strand RNA viruses. Virology (2003) 1.25
Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis. Proc Natl Acad Sci U S A (2012) 1.24
Molecular imaging of gene expression and protein function in vivo with PET and SPECT. J Magn Reson Imaging (2002) 1.21
Applications of bioluminescence imaging to antiviral research and therapy: multiple luciferase enzymes and quantitation. Antiviral Res (2008) 1.18
Microfluidic platform for chemotaxis in gradients formed by CXCL12 source-sink cells. Integr Biol (Camb) (2010) 1.17
Structure and intracellular targeting of the SARS-coronavirus Orf7a accessory protein. Structure (2005) 1.16
The RNA binding domain of influenza A virus NS1 protein affects secretion of tumor necrosis factor alpha, interleukin-6, and interferon in primary murine tracheal epithelial cells. J Virol (2007) 1.13
Mind the gap: social media engagement by public health researchers. J Med Internet Res (2014) 1.12
Tropism and infectivity of influenza virus, including highly pathogenic avian H5N1 virus, in ferret tracheal differentiated primary epithelial cell cultures. J Virol (2012) 1.10
The impact of sex, gender and pregnancy on 2009 H1N1 disease. Biol Sex Differ (2010) 1.10
The ORF7b protein of severe acute respiratory syndrome coronavirus (SARS-CoV) is expressed in virus-infected cells and incorporated into SARS-CoV particles. J Virol (2006) 1.09
Monitoring serial changes in circulating human breast cancer cells in murine xenograft models. Cancer Res (2008) 1.09
Differentiated cultures of primary hamster tracheal airway epithelial cells. In Vitro Cell Dev Biol Anim (2005) 1.08
Roles for the recycling endosome, Rab8, and Rab11 in hantavirus release from epithelial cells. Virology (2008) 1.06
Vaccinia virus infection induces dendritic cell maturation but inhibits antigen presentation by MHC class II. Cell Immunol (2007) 1.05
Generation of a highly inducible Gal4-->Fluc universal reporter mouse for in vivo bioluminescence imaging. Proc Natl Acad Sci U S A (2008) 1.04
A novel, killed-virus nasal vaccinia virus vaccine. Clin Vaccine Immunol (2007) 1.03
Severe acute respiratory syndrome coronavirus gene 7 products contribute to virus-induced apoptosis. J Virol (2007) 1.02
Murine alveolar macrophages limit replication of vaccinia virus. Virology (2007) 1.02
In Vivo Monitoring of Multiple Circulating Cell Populations Using Two-photon Flow Cytometry. Opt Commun (2008) 1.02
Protective effect of Toll-like receptor 4 in pulmonary vaccinia infection. PLoS Pathog (2008) 1.02
Noninvasive imaging reveals inhibition of ovarian cancer by targeting CXCL12-CXCR4. Neoplasia (2011) 1.00
Palmitoylation of the influenza A virus M2 protein is not required for virus replication in vitro but contributes to virus virulence. J Virol (2009) 1.00
Type I interferon regulates respiratory virus infected dendritic cell maturation and cytokine production. Viral Immunol (2007) 1.00
Tyrosines in the influenza A virus M2 protein cytoplasmic tail are critical for production of infectious virus particles. J Virol (2010) 0.99
Bidirectional virus secretion and nonciliated cell tropism following Andes virus infection of primary airway epithelial cell cultures. J Virol (2006) 0.98
Secreted CXCL12 (SDF-1) forms dimers under physiological conditions. Biochem J (2012) 0.95
Bioluminescence imaging of reporter mice for studies of infection and inflammation. Antiviral Res (2010) 0.95
Transgenic reporter mouse for bioluminescence imaging of herpes simplex virus 1 infection in living mice. Virology (2006) 0.93
NanoLuc reporter for dual luciferase imaging in living animals. Mol Imaging (2013) 0.93
The cholesterol recognition/interaction amino acid consensus motif of the influenza A virus M2 protein is not required for virus replication but contributes to virulence. Virology (2010) 0.91
Antibody responses and cross protection against lethal influenza A viruses differ between the sexes in C57BL/6 mice. Vaccine (2011) 0.90
Polymeric Aqueous Biphasic System Rehydration Facilitates High Throughput Cell Exclusion Patterning For Cell Migration Studies. Adv Funct Mater (2011) 0.89
Carboxy-terminus of CXCR7 regulates receptor localization and function. Int J Biochem Cell Biol (2012) 0.89
Imaging CXCL12-CXCR4 signaling in ovarian cancer therapy. PLoS One (2013) 0.88
Targeted non-covalent self-assembled nanoparticles based on human serum albumin. Biomaterials (2011) 0.88
Extending the cytoplasmic tail of the influenza a virus M2 protein leads to reduced virus replication in vivo but not in vitro. J Virol (2007) 0.87
Influenza A virus infection of primary differentiated airway epithelial cell cultures derived from Syrian golden hamsters. Virology (2006) 0.87
Delivery of woodchuck hepatitis virus-like particle presented influenza M2e by recombinant attenuated Salmonella displaying a delayed lysis phenotype. Vaccine (2010) 0.87
Prospects for oral replicating adenovirus-vectored vaccines. Vaccine (2013) 0.86
Advancing the translation of optical imaging agents for clinical imaging. Biomed Opt Express (2012) 0.86
Mutations in the membrane-proximal region of the influenza A virus M2 protein cytoplasmic tail have modest effects on virus replication. J Virol (2011) 0.85
An immunosuppressed Syrian golden hamster model for SARS-CoV infection. Virology (2008) 0.84
Synthesis and investigation of a radioiodinated F3 peptide analog as a SPECT tumor imaging radioligand. PLoS One (2011) 0.84
Cell-based and in vivo spectral analysis of fluorescent proteins for multiphoton microscopy. J Biomed Opt (2012) 0.83
Extended cavity laser enhanced two-photon flow cytometry. J Biomed Opt (2008) 0.83
The transmembrane domain of the severe acute respiratory syndrome coronavirus ORF7b protein is necessary and sufficient for its retention in the Golgi complex. J Virol (2008) 0.82
Transfer, imaging, and analysis plate for facile handling of 384 hanging drop 3D tissue spheroids. J Lab Autom (2013) 0.82
Imaging pulmonary gene expression with positron emission tomography. Am J Respir Crit Care Med (2002) 0.81
Influenza virus assays based on virus-inducible reporter cell lines. Influenza Other Respir Viruses (2009) 0.81
Applications of molecular imaging. Prog Mol Biol Transl Sci (2010) 0.81
Multiplexed spectral signature detection for microfluidic color-coded bioparticle flow. Anal Chem (2010) 0.80
Production and characterization of monoclonal antibodies against the nucleocapsid protein of SARS-CoV. Adv Exp Med Biol (2006) 0.79
Longitudinal molecular imaging with single cell resolution of disseminated ovarian cancer in mice with a LED-based confocal microendoscope. Mol Imaging Biol (2011) 0.79
Real-time bioluminescence imaging of viral pathogenesis. Methods Mol Biol (2009) 0.79
Seoul virus suppresses NF-kappaB-mediated inflammatory responses of antigen presenting cells from Norway rats. Virology (2010) 0.78
Transcriptional profiling of the spleen in progressive visceral leishmaniasis reveals mixed expression of type 1 and type 2 cytokine-responsive genes. BMC Immunol (2014) 0.77
Phytochemicals potently inhibit migration of metastatic breast cancer cells. Integr Biol (Camb) (2015) 0.76
CXCR4-Targeted Nanocarriers for Triple Negative Breast Cancers. Biomacromolecules (2015) 0.76
Allosteric peptide regulators of chemokine receptors CXCR4 and CXCR7. Biochem Pharmacol (2013) 0.76
Imaging Reporters for Proteasome Activity Identify Tumor- and Metastasis-Initiating Cells. Mol Imaging (2015) 0.75
Correction: Cell, Isoform, and Environment Factors Shape Gradients and Modulate Chemotaxis. PLoS One (2017) 0.75
Split Gaussia luciferase for imaging ligand-receptor binding. Methods Mol Biol (2014) 0.75
Editor's Recognition Awards. Radiol Imaging Cancer (2022) 0.75
Dispersible oxygen microsensors map oxygen gradients in three-dimensional cell cultures. Biomater Sci (2017) 0.75
2021 Manuscript Reviewers: A Note of Thanks. Radiol Imaging Cancer (2022) 0.75