David Karasik

Author PubWeight™ 77.15‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet 2010 8.89
2 Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet 2012 5.48
3 Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet 2009 5.32
4 Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet 2010 3.37
5 Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. Ann Intern Med 2009 2.80
6 Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet 2011 2.73
7 Meta-analysis of genome-wide association data identifies two loci influencing age at menarche. Nat Genet 2009 2.58
8 Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies. Am J Hum Genet 2010 2.57
9 Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis. JAMA 2008 2.52
10 An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. PLoS Genet 2010 2.43
11 Genome-wide association with bone mass and geometry in the Framingham Heart Study. BMC Med Genet 2007 2.32
12 Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. BMC Med Genet 2007 2.25
13 Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet 2012 2.12
14 A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. J Gerontol A Biol Sci Med Sci 2010 1.65
15 Assessment of gene-by-sex interaction effect on bone mineral density. J Bone Miner Res 2012 1.58
16 A genome-wide association study of aging. Neurobiol Aging 2011 1.54
17 PPARG by dietary fat interaction influences bone mass in mice and humans. J Bone Miner Res 2008 1.50
18 Genetic determinants of serum testosterone concentrations in men. PLoS Genet 2011 1.45
19 Impact of common variation in bone-related genes on type 2 diabetes and related traits. Diabetes 2012 1.42
20 Genetic variation at the low-density lipoprotein receptor-related protein 5 (LRP5) locus modulates Wnt signaling and the relationship of physical activity with bone mineral density in men. Bone 2006 1.27
21 A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet 2012 1.23
22 Bone geometry and skeletal fragility. Curr Osteoporos Rep 2006 1.20
23 Mouse BMD quantitative trait loci show improved concordance with human genome-wide association loci when recalculated on a new, common mouse genetic map. J Bone Miner Res 2010 1.17
24 Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women. J Bone Miner Res 2013 1.16
25 Interactions of interleukin-6 promoter polymorphisms with dietary and lifestyle factors and their association with bone mass in men and women from the Framingham Osteoporosis Study. J Bone Miner Res 2004 1.13
26 Hip structural geometry in old and old-old age: similarities and differences between men and women. Bone 2007 1.06
27 Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. Hum Mol Genet 2014 1.02
28 Identification of homogeneous genetic architecture of multiple genetically correlated traits by block clustering of genome-wide associations. J Bone Miner Res 2011 0.99
29 Increased plasma osteoprotegerin concentrations are associated with indices of bone strength of the hip. J Clin Endocrinol Metab 2008 0.98
30 Large common deletions associate with mortality at old age. Hum Mol Genet 2011 0.96
31 Estrogen receptor beta polymorphisms are associated with bone mass in women and men: the Framingham Study. J Bone Miner Res 2003 0.93
32 Association of a common polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene with bone phenotypes depends on plasma folate status. J Bone Miner Res 2003 0.92
33 Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus. Bone 2014 0.88
34 DNA mismatch repair gene MSH6 implicated in determining age at natural menopause. Hum Mol Genet 2013 0.88
35 Hip geometry variation is associated with bone mineralization pathway gene variants: The Framingham Study. J Bone Miner Res 2010 0.86
36 Heritability of prevalent vertebral fracture and volumetric bone mineral density and geometry at the lumbar spine in three generations of the Framingham study. J Bone Miner Res 2012 0.86
37 A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus. J Med Genet 2013 0.84
38 Genetic variation in TRPS1 may regulate hip geometry as well as bone mineral density. Bone 2012 0.84
39 Complex segregation analysis of the radiographic phalanges bone mineral density and their age-related changes. J Bone Miner Res 2002 0.81
40 Impact of the environment on the skeleton: is it modulated by genetic factors? Curr Osteoporos Rep 2013 0.77
41 The genetics of bone mass and susceptibility to bone diseases. Nat Rev Rheumatol 2016 0.75
42 A Polymorphism in a gene encoding Perilipin 4 is associated with height but not with bone measures in individuals from the Framingham Osteoporosis Study. Calcif Tissue Int 2011 0.75
43 Corrigendum: Rare coding variants and X-linked loci associated with age at menarche. Nat Commun 2015 0.75