Published in J Bone Miner Res on August 01, 2010
Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis. PLoS Genet (2011) 1.68
Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture. Nature (2015) 1.53
Bicc1 is a genetic determinant of osteoblastogenesis and bone mineral density. J Clin Invest (2014) 1.53
Congenic mice provide in vivo evidence for a genetic locus that modulates intrinsic transforming growth factor β1-mediated signaling and bone acquisition. J Bone Miner Res (2012) 1.41
Quantitative trait loci for bone mineral density and femoral morphology in an advanced intercross population of mice. Bone (2013) 1.40
Functional genomics complements quantitative genetics in identifying disease-gene associations. PLoS Comput Biol (2010) 1.20
HDL cholesterol and bone mineral density: is there a genetic link? Bone (2012) 0.99
Sequence variation at multiple loci influences red cell hemoglobin concentration. Blood (2010) 0.92
Severity of innate immune-mediated colitis is controlled by the cytokine deficiency-induced colitis susceptibility-1 (Cdcs1) locus. Proc Natl Acad Sci U S A (2011) 0.90
Multiple quantitative trait loci for cortical and trabecular bone regulation map to mid-distal mouse chromosome 4 that shares linkage homology to human chromosome 1p36. J Bone Miner Res (2012) 0.86
Genetic variation in TRPS1 may regulate hip geometry as well as bone mineral density. Bone (2012) 0.84
Joint genetic analysis of hippocampal size in mouse and human identifies a novel gene linked to neurodegenerative disease. BMC Genomics (2014) 0.83
Identification of quantitative trait loci influencing skeletal architecture in mice: emergence of Cdh11 as a primary candidate gene regulating femoral morphology. J Bone Miner Res (2011) 0.83
Aging Research Using Mouse Models. Curr Protoc Mouse Biol (2015) 0.82
The genetics of bone mass and susceptibility to bone diseases. Nat Rev Rheumatol (2016) 0.82
Systems genetics: a novel approach to dissect the genetic basis of osteoporosis. Curr Osteoporos Rep (2012) 0.81
Recalculation of 23 mouse HDL QTL datasets improves accuracy and allows for better candidate gene analysis. J Lipid Res (2013) 0.79
Genetic regulation of bone strength: a review of animal model studies. Bonekey Rep (2015) 0.77
Congenic Strains Confirm the Pleiotropic Effect of Chromosome 4 QTL on Mouse Femoral Geometry and Biomechanical Performance. PLoS One (2016) 0.77
Impact of the environment on the skeleton: is it modulated by genetic factors? Curr Osteoporos Rep (2013) 0.77
The need for mouse models in osteoporosis genetics research. Bonekey Rep (2012) 0.76
Novel Genetic Loci Control Calcium Absorption and Femur Bone Mass as Well as Their Response to Low Calcium Intake in Male BXD Recombinant Inbred Mice. J Bone Miner Res (2016) 0.76
A cross-species genetic analysis identifies candidate genes for mouse anxiety and human bipolar disorder. Front Behav Neurosci (2015) 0.76
Genetics of aging bone. Mamm Genome (2016) 0.76
Gene-by-Diet Interactions Affect Serum 1,25-Dihydroxyvitamin D Levels in Male BXD Recombinant Inbred Mice. Endocrinology (2015) 0.75
Genetic Dissection of Trabecular Bone Structure with Mouse Inter-subspecific Consomic Strains. G3 (Bethesda) (2017) 0.75
Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet (1995) 49.77
Empirical threshold values for quantitative trait mapping. Genetics (1994) 46.95
R/qtl: QTL mapping in experimental crosses. Bioinformatics (2003) 22.38
A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits. Nat Genet (2009) 7.65
A statistical framework for quantitative trait mapping. Genetics (2001) 7.55
Genome-wide association studies: potential next steps on a genetic journey. Hum Mol Genet (2008) 7.54
Maps from two interspecific backcross DNA panels available as a community genetic mapping resource. Mamm Genome (1994) 5.38
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet (2009) 5.32
A high-resolution single nucleotide polymorphism genetic map of the mouse genome. PLoS Biol (2006) 4.57
The Mouse Genome Database (MGD). A comprehensive public resource of genetic, phenotypic and genomic data. The Mouse Genome Informatics Group. Nucleic Acids Res (1997) 4.31
A genetic map of the mouse with 4,006 simple sequence length polymorphisms. Nat Genet (1994) 4.20
Genetic variability in adult bone density among inbred strains of mice. Bone (1996) 3.66
The Mouse Genome Database genotypes::phenotypes. Nucleic Acids Res (2008) 3.48
Quantitative trait loci for femoral and lumbar vertebral bone mineral density in C57BL/6J and C3H/HeJ inbred strains of mice. J Bone Miner Res (2001) 2.94
A new standard genetic map for the laboratory mouse. Genetics (2009) 2.78
Bioinformatics toolbox for narrowing rodent quantitative trait loci. Trends Genet (2005) 2.24
Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups. Am J Hum Genet (2009) 2.14
Sex- and lineage-specific inheritance of depression-like behavior in the rat. Mamm Genome (2004) 1.99
Genetic regulation of bone mass and susceptibility to osteoporosis. Genes Dev (2006) 1.86
Meta-analysis of genome-wide scans provides evidence for sex- and site-specific regulation of bone mass. J Bone Miner Res (2007) 1.82
Gender specificity in the genetic determinants of peak bone mass. J Bone Miner Res (2001) 1.80
Genetic loci determining bone density in mice with diet-induced atherosclerosis. Physiol Genomics (2001) 1.79
Congenic strains of mice for verification and genetic decomposition of quantitative trait loci for femoral bone mineral density. J Bone Miner Res (2003) 1.78
Control of the SOST bone enhancer by PTH using MEF2 transcription factors. J Bone Miner Res (2007) 1.74
Quantitative trait loci for bone density in C57BL/6J and CAST/EiJ inbred mice. Mamm Genome (1999) 1.68
Combining data from multiple inbred line crosses improves the power and resolution of quantitative trait loci mapping. Genetics (2005) 1.58
Genetics of variation in HDL cholesterol in humans and mice. Circ Res (2005) 1.58
Molecular genetic studies of gene identification for osteoporosis: a 2004 update. J Bone Miner Res (2006) 1.52
PPARG by dietary fat interaction influences bone mass in mice and humans. J Bone Miner Res (2008) 1.50
Practical applications of the bioinformatics toolbox for narrowing quantitative trait loci. Genetics (2008) 1.49
Genetic effects for femoral biomechanics, structure, and density in C57BL/6J and C3H/HeJ inbred mouse strains. J Bone Miner Res (2003) 1.37
An integrative genetics approach to identify candidate genes regulating BMD: combining linkage, gene expression, and association. J Bone Miner Res (2009) 1.33
Genetic dissection of femur breaking strength in a large population (MRL/MpJ x SJL/J) of F2 Mice: single QTL effects, epistasis, and pleiotropy. Genomics (2002) 1.29
Quantitative trait loci that determine plasma lipids and obesity in C57BL/6J and 129S1/SvImJ inbred mice. J Lipid Res (2004) 1.28
Strain-specific effects of rosiglitazone on bone mass, body composition, and serum insulin-like growth factor-I. Endocrinology (2008) 1.26
Genetic dissection of mouse distal chromosome 1 reveals three linked BMD QTLs with sex-dependent regulation of bone phenotypes. J Bone Miner Res (2007) 1.26
Identification of mouse Duffy antigen receptor for chemokines (Darc) as a BMD QTL gene. Genome Res (2007) 1.21
Femur mechanical properties in the F2 progeny of an NZB/B1NJ x RF/J cross are regulated predominantly by genetic loci that regulate bone geometry. J Bone Miner Res (2006) 1.19
Quantitative trait loci that determine BMD in C57BL/6J and 129S1/SvImJ inbred mice. J Bone Miner Res (2005) 1.17
Four additional mouse crosses improve the lipid QTL landscape and identify Lipg as a QTL gene. J Lipid Res (2009) 1.16
Quantitative trait loci for bone density in mice: the genes determining total skeletal density and femur density show little overlap in F2 mice. Calcif Tissue Int (2002) 1.16
Human genetics of osteoporosis. Best Pract Res Clin Endocrinol Metab (2008) 1.10
In search of new targets for plasma high-density lipoprotein cholesterol levels: promise of human-mouse comparative genomics. Trends Cardiovasc Med (2006) 1.10
Quantitative trait loci for BMD in an SM/J by NZB/BlNJ intercross population and identification of Trps1 as a probable candidate gene. J Bone Miner Res (2008) 1.10
Confirmation and fine mapping of chromosomal regions influencing peak bone mass in mice. J Bone Miner Res (2001) 1.07
Genetic regulation of femoral bone mineral density: complexity of sex effect in chromosome 1 revealed by congenic sublines of mice. Bone (2007) 1.06
Chromosomal mapping of osteopenia-associated quantitative trait loci using closely related mouse strains. J Bone Miner Res (2000) 1.05
Meta-analysis of genome-wide linkage studies for bone mineral density. J Hum Genet (2006) 1.02
Detecting novel bone density and bone size quantitative trait loci using a cross of MRL/MpJ and CAST/EiJ inbred mice. Calcif Tissue Int (2007) 0.95
Identification of quantitative trait loci affecting body composition in a mouse intercross. Proc Natl Acad Sci U S A (2006) 0.89
A differential association of ALOX15 polymorphisms with bone mineral density in pre- and post-menopausal women. Hum Hered (2007) 0.88
Multiple genetic loci from CAST/EiJ chromosome 1 affect vBMD either positively or negatively in a C57BL/6J background. J Bone Miner Res (2005) 0.88
Mapping quantitative trait loci that influence serum insulin-like growth factor binding protein-5 levels in F2 mice (MRL/MpJ X SJL/J). Endocrinology (2003) 0.88
Genetic regulation of bone mineral density in mice. J Musculoskelet Neuronal Interact (2002) 0.86
Quantitative trait loci that harbor genes regulating muscle size in (MRL/MPJ x SJL/J) F(2) mice. Funct Integr Genomics (2002) 0.86
Replication study of candidate genes/loci associated with osteoporosis based on genome-wide screening. Osteoporos Int (2009) 0.84
R/qtl: QTL mapping in experimental crosses. Bioinformatics (2003) 22.38
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol (2007) 10.49
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol (2007) 9.36
Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89
Statistical tests for differential expression in cDNA microarray experiments. Genome Biol (2003) 7.65
Variation in gene expression within and among natural populations. Nat Genet (2002) 7.19
FTO Obesity Variant Circuitry and Adipocyte Browning in Humans. N Engl J Med (2015) 6.48
Improved statistical tests for differential gene expression by shrinking variance components estimates. Biostatistics (2005) 5.57
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet (2009) 5.32
On the subspecific origin of the laboratory mouse. Nat Genet (2007) 4.68
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
Subspecific origin and haplotype diversity in the laboratory mouse. Nat Genet (2011) 3.64
The mouse as a model for human biology: a resource guide for complex trait analysis. Nat Rev Genet (2007) 3.55
A customized and versatile high-density genotyping array for the mouse. Nat Methods (2009) 3.53
The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics. Mamm Genome (2008) 3.52
Nuclear envelope budding enables large ribonucleoprotein particle export during synaptic Wnt signaling. Cell (2012) 3.50
miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1. Nat Med (2010) 3.50
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer. Cell (2009) 3.34
High-resolution genetic mapping using the Mouse Diversity outbred population. Genetics (2012) 3.28
Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res (2011) 3.25
Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels. Aging Cell (2009) 3.16
Bayesian model selection for genome-wide epistatic quantitative trait loci analysis. Genetics (2005) 3.10
Prevalence of calcidiol deficiency in CKD: a cross-sectional study across latitudes in the United States. Am J Kidney Dis (2005) 2.82
Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. Ann Intern Med (2009) 2.80
A new standard genetic map for the laboratory mouse. Genetics (2009) 2.78
Dysregulation of HSG triggers vascular proliferative disorders. Nat Cell Biol (2004) 2.75
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet (2011) 2.73
Evidence of a large-scale functional organization of mammalian chromosomes. PLoS Genet (2005) 2.73
Multiple trait measurements in 43 inbred mouse strains capture the phenotypic diversity characteristic of human populations. J Appl Physiol (1985) (2007) 2.70
Meta-analysis of genome-wide association data identifies two loci influencing age at menarche. Nat Genet (2009) 2.58
Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies. Am J Hum Genet (2010) 2.57
An imputed genotype resource for the laboratory mouse. Mamm Genome (2008) 2.54
Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis. JAMA (2008) 2.52
Structural model analysis of multiple quantitative traits. PLoS Genet (2006) 2.45
An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. PLoS Genet (2010) 2.43
Facilitation of μ-opioid receptor activity by preventing δ-opioid receptor-mediated codegradation. Neuron (2011) 2.42
Crossover interference in the mouse. Genetics (2002) 2.40
Genome-wide association with bone mass and geometry in the Framingham Heart Study. BMC Med Genet (2007) 2.32
Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. BMC Med Genet (2007) 2.25
Transformations for cDNA microarray data. Stat Appl Genet Mol Biol (2003) 2.23
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet (2012) 2.12
Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice. Cell Metab (2010) 2.09
Effects of atherogenic diet on hepatic gene expression across mouse strains. Physiol Genomics (2009) 2.00
Sex- and lineage-specific inheritance of depression-like behavior in the rat. Mamm Genome (2004) 1.99
Macromolecule biosynthesis: a key function of sleep. Physiol Genomics (2007) 1.93
Dinitrosyliron complexes and the mechanism(s) of cellular protein nitrosothiol formation from nitric oxide. Proc Natl Acad Sci U S A (2009) 1.84
Association between iron deficiency and blood lead level in a longitudinal analysis of children followed in an urban primary care clinic. J Pediatr (2003) 1.83
A collaborative database of inbred mouse strain characteristics. Bioinformatics (2004) 1.79
Isoflurane anesthesia induced persistent, progressive memory impairment, caused a loss of neural stem cells, and reduced neurogenesis in young, but not adult, rodents. J Cereb Blood Flow Metab (2010) 1.75
Quantitative trait locus analysis for obesity reveals multiple networks of interacting loci. Mamm Genome (2006) 1.74
Genetic analysis in the Collaborative Cross breeding population. Genome Res (2011) 1.74
Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis. Proc Natl Acad Sci U S A (2011) 1.69
Maternal bone lead as an independent risk factor for fetal neurotoxicity: a prospective study. Pediatrics (2002) 1.67
Using advanced intercross lines for high-resolution mapping of HDL cholesterol quantitative trait loci. Genome Res (2003) 1.66
The X chromosome in quantitative trait locus mapping. Genetics (2006) 1.65
A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. J Gerontol A Biol Sci Med Sci (2010) 1.65
HAT4, a Golgi apparatus-anchored B-type histone acetyltransferase, acetylates free histone H4 and facilitates chromatin assembly. Mol Cell (2011) 1.59
Crosstalk between Aurora-A and p53: frequent deletion or downregulation of Aurora-A in tumors from p53 null mice. Cancer Cell (2007) 1.59
Combining data from multiple inbred line crosses improves the power and resolution of quantitative trait loci mapping. Genetics (2005) 1.58
Assessment of gene-by-sex interaction effect on bone mineral density. J Bone Miner Res (2012) 1.58
Effects of subchronic exposures to concentrated ambient particles (CAPs) in mice. II. The design of a CAPs exposure system for biometric telemetry monitoring. Inhal Toxicol (2005) 1.58
Quantitative trait loci analysis for plasma HDL-cholesterol concentrations and atherosclerosis susceptibility between inbred mouse strains C57BL/6J and 129S1/SvImJ. Arterioscler Thromb Vasc Biol (2003) 1.58
Statistical design and the analysis of gene expression microarray data. Genet Res (2007) 1.56
Perisinusoidal B cells in the bone marrow participate in T-independent responses to blood-borne microbes. Immunity (2005) 1.54
A genome-wide association study of aging. Neurobiol Aging (2011) 1.54
Bicc1 is a genetic determinant of osteoblastogenesis and bone mineral density. J Clin Invest (2014) 1.53
The MTA family proteins as novel histone H3 binding proteins. Cell Biosci (2013) 1.52
Coral energy reserves and calcification in a high-CO2 world at two temperatures. PLoS One (2013) 1.52
Mapping quantitative trait loci for vertebral trabecular bone volume fraction and microarchitecture in mice. J Bone Miner Res (2003) 1.52
A torrid zone on mouse chromosome 1 containing a cluster of recombinational hotspots. Genetics (2004) 1.51
PPARgamma2 nuclear receptor controls multiple regulatory pathways of osteoblast differentiation from marrow mesenchymal stem cells. J Cell Biochem (2009) 1.51
PPARG by dietary fat interaction influences bone mass in mice and humans. J Bone Miner Res (2008) 1.50
Ten years of the collaborative cross. G3 (Bethesda) (2012) 1.50
Practical applications of the bioinformatics toolbox for narrowing quantitative trait loci. Genetics (2008) 1.49
Percent fat mass is inversely associated with bone mass and hip geometry in rural Chinese adolescents. J Bone Miner Res (2010) 1.47
Short-term ex vivo expansion sustains the homing-related properties of umbilical cord blood hematopoietic stem and progenitor cells. Haematologica (2004) 1.46
Genetic determinants of serum testosterone concentrations in men. PLoS Genet (2011) 1.45
A new simple model for prediction of hospital mortality in patients with intracerebral hemorrhage. CNS Neurosci Ther (2012) 1.45
Microarrays with varying carbohydrate density reveal distinct subpopulations of serum antibodies. J Proteome Res (2009) 1.45
Novel mutations of the FRMD7 gene in X-linked congenital motor nystagmus. Mol Vis (2007) 1.45
Optical coherence tomography of human kidney. J Urol (2010) 1.44
Modeling host genetic regulation of influenza pathogenesis in the collaborative cross. PLoS Pathog (2013) 1.43
Determinants of childhood immunization uptake among socio-economically disadvantaged migrants in East China. Int J Environ Res Public Health (2013) 1.42
Impact of common variation in bone-related genes on type 2 diabetes and related traits. Diabetes (2012) 1.42
Imputation of single-nucleotide polymorphisms in inbred mice using local phylogeny. Genetics (2012) 1.42