Barbara Sedgwick

Author PubWeight™ 29.22^‹?›

Rank	Title	Journal	Year	PubWeight™‹?›
1	The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase.	Science	2007	9.86
2	Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage.	Nature	2002	5.47
3	Reversal of DNA alkylation damage by two human dioxygenases.	Proc Natl Acad Sci U S A	2002	3.62
4	Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations.	Am J Hum Genet	2009	2.09
5	Demethylation of 3-methylthymine in DNA by bacterial and human DNA dioxygenases.	J Biol Chem	2004	1.94
6	Prevalence of loss-of-function FTO mutations in lean and obese individuals.	Diabetes	2009	1.54
7	Minimal methylated substrate and extended substrate range of Escherichia coli AlkB protein, a 1-methyladenine-DNA dioxygenase.	J Biol Chem	2003	1.53
8	Sensitization of human carcinoma cells to alkylating agents by small interfering RNA suppression of 3-alkyladenine-DNA glycosylase.	Cancer Res	2005	1.08
9	Dynamic states of the DNA repair enzyme AlkB regulate product release.	EMBO Rep	2008	1.03
10	Resonance assignments of Escherichia coli AlkB: a key 2-oxoglutarate and Fe(II) dependent dioxygenase of the adaptive DNA-repair response.	J Biomol NMR	2005	0.80
11	Replacement of non-heme Fe(II) with Cu(II) in the alpha-ketoglutarate dependent DNA repair enzyme AlkB: spectroscopic characterization of the active site.	J Inorg Biochem	2007	0.79