Molecular basis for the role of Staphylococcus aureus penicillin binding protein 4 in antimicrobial resistance.

PubWeight™: 1.07‹?› | Rank: Top 10%

🔗 View Article (PMC 2798245)

Published in J Bacteriol on January 01, 2010

Authors

Vikas Navratna1, Savitha Nadig, Varun Sood, K Prasad, Gayathri Arakere, B Gopal

Author Affiliations

1: Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India.

Articles citing this

A mecA-negative strain of methicillin-resistant Staphylococcus aureus with high-level β-lactam resistance contains mutations in three genes. Antimicrob Agents Chemother (2010) 1.26

Antimicrobial effect and mode of action of terpeneless cold-pressed Valencia orange essential oil on methicillin-resistant Staphylococcus aureus. J Appl Microbiol (2012) 1.08

Genome-wide dynamics of a bacterial response to antibiotics that target the cell envelope. BMC Genomics (2011) 1.03

Detection of lipid-linked peptidoglycan precursors by exploiting an unexpected transpeptidase reaction. J Am Chem Soc (2014) 0.97

Dual roles of FmtA in Staphylococcus aureus cell wall biosynthesis and autolysis. Antimicrob Agents Chemother (2012) 0.93

Specialized peptidoglycan hydrolases sculpt the intra-bacterial niche of predatory Bdellovibrio and increase population fitness. PLoS Pathog (2012) 0.90

Whole-Genome Sequencing of Methicillin-Resistant Staphylococcus aureus Resistant to Fifth-Generation Cephalosporins Reveals Potential Non-mecA Mechanisms of Resistance. PLoS One (2016) 0.89

Combinations of cefoxitin plus other β-lactams are synergistic in vitro against community associated methicillin-resistant Staphylococcus aureus. Eur J Clin Microbiol Infect Dis (2013) 0.88

Distinctive Binding of Avibactam to Penicillin-Binding Proteins of Gram-Negative and Gram-Positive Bacteria. Antimicrob Agents Chemother (2015) 0.87

The solvent component of macromolecular crystals. Acta Crystallogr D Biol Crystallogr (2015) 0.85

Detection of epidemic USA300 community-associated methicillin-resistant Staphylococcus aureus strains by use of a single allele-specific PCR assay targeting a novel polymorphism of Staphylococcus aureus pbp3. J Clin Microbiol (2013) 0.81

The Staphylococcus aureus Chaperone PrsA Is a New Auxiliary Factor of Oxacillin Resistance Affecting Penicillin-Binding Protein 2A. Antimicrob Agents Chemother (2015) 0.80

Regulation of expression of abcA and its response to environmental conditions. J Bacteriol (2014) 0.79

PCR-based identification of methicillin-resistant Staphylococcus aureus strains and their antibiotic resistance profiles. Asian Pac J Trop Biomed (2014) 0.78

PBP 4 Mediates High-Level Resistance to New-Generation Cephalosporins in Staphylococcus aureus. Antimicrob Agents Chemother (2016) 0.78

Novel Penicillin Analogues as Potential Antimicrobial Agents; Design, Synthesis and Docking Studies. PLoS One (2015) 0.75

Synergistic antibacterial effects of herbal extracts and antibiotics on methicillin-resistant Staphylococcus aureus: A computational and experimental study. Exp Biol Med (Maywood) (2017) 0.75

The Allosteric Site for the Nascent Cell Wall in Penicillin-Binding Protein 2a: An Achilles' Heel of Methicillin-Resistant Staphylococcus aureus. Curr Med Chem (2015) 0.75

Synthesis and biological evaluation of the progenitor of a new class of cephalosporin analogues, with a particular focus on structure-based computational analysis. PLoS One (2017) 0.75

Articles cited by this

Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr (2004) 227.01

Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr D Biol Crystallogr (1997) 137.43

Scaling and assessment of data quality. Acta Crystallogr D Biol Crystallogr (2005) 61.38

Likelihood-enhanced fast translation functions. Acta Crystallogr D Biol Crystallogr (2005) 29.38

Likelihood-enhanced fast rotation functions. Acta Crystallogr D Biol Crystallogr (2004) 23.86

A standard numbering scheme for the class A beta-lactamases. Biochem J (1991) 17.44

Low-affinity penicillin-binding protein associated with beta-lactam resistance in Staphylococcus aureus. J Bacteriol (1984) 14.64

Structural comparison of three types of staphylococcal cassette chromosome mec integrated in the chromosome in methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother (2001) 12.65

ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures. Nucleic Acids Res (2005) 10.60

A new class of genetic element, staphylococcus cassette chromosome mec, encodes methicillin resistance in Staphylococcus aureus. Antimicrob Agents Chemother (2000) 9.84

Cloning and nucleotide sequence determination of the entire mec DNA of pre-methicillin-resistant Staphylococcus aureus N315. Antimicrob Agents Chemother (1999) 8.36

Serine beta-lactamases and penicillin-binding proteins. Annu Rev Microbiol (1991) 6.63

Penicillin-binding proteins and the mechanism of action of beta-lactam antibiotics. Annu Rev Biochem (1983) 6.24

Evolutionary genomics of Staphylococcus aureus: insights into the origin of methicillin-resistant strains and the toxic shock syndrome epidemic. Proc Natl Acad Sci U S A (2001) 6.22

Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencing. Proc Natl Acad Sci U S A (2007) 6.14

The Rossmann Fourier autoindexing algorithm in MOSFLM. Acta Crystallogr D Biol Crystallogr (1999) 5.96

Bacterial resistance to beta-lactam antibiotics: crystal structure of beta-lactamase from Staphylococcus aureus PC1 at 2.5 A resolution. Science (1987) 5.35

Multimodular penicillin-binding proteins: an enigmatic family of orthologs and paralogs. Microbiol Mol Biol Rev (1998) 4.70

Insights on antibiotic resistance of Staphylococcus aureus from its whole genome: genomic island SCC. Drug Resist Updat (2003) 4.40

Escherichia coli mutants lacking all possible combinations of eight penicillin binding proteins: viability, characteristics, and implications for peptidoglycan synthesis. J Bacteriol (1999) 3.41

A membrane enzyme from Staphylococcus aureus which catalyzes transpeptidase, carboxypeptidase, and penicillinase activities. J Biol Chem (1978) 3.07

A role in vivo for penicillin-binding protein-4 of Staphylococcus aureus. Eur J Biochem (1981) 2.99

The prevalence and mechanisms of vancomycin resistance in Staphylococcus aureus. Annu Rev Microbiol (2002) 2.77

Beta-lactam resistance response triggered by inactivation of a nonessential penicillin-binding protein. PLoS Pathog (2009) 2.20

Physical and genetic mapping of the protein A gene in the chromosome of Staphylococcus aureus 8325-4. J Gen Microbiol (1989) 1.97

Role of penicillin-binding protein 4 in expression of vancomycin resistance among clinical isolates of oxacillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother (2001) 1.81

Nucleotide sequence of the structural gene for the penicillin-binding protein 2 of Staphylococcus aureus and the presence of a homologous gene in other staphylococci. FEMS Microbiol Lett (1994) 1.79

Staphylococcus aureus PBP4 is essential for beta-lactam resistance in community-acquired methicillin-resistant strains. Antimicrob Agents Chemother (2008) 1.67

Penicillin-binding protein 4 overproduction increases beta-lactam resistance in Staphylococcus aureus. Antimicrob Agents Chemother (1996) 1.55

Consequences of the interaction of beta-lactam antibiotics with penicillin binding proteins from sensitive and resistant Staphylococcus aureus strains. Med Microbiol Immunol (1992) 1.53

Transcriptional analysis of the Staphylococcus aureus penicillin binding protein 2 gene. J Bacteriol (1998) 1.50

Serine-type D-Ala-D-Ala peptidases and penicillin-binding proteins. Methods Enzymol (1994) 1.46

Staphylococcus aureus penicillin-binding protein 4 and intrinsic beta-lactam resistance. Antimicrob Agents Chemother (1995) 1.45

Discrimination of extended-spectrum beta-lactamases by a novel nitrocefin competition assay. Antimicrob Agents Chemother (1990) 1.36

Kinetics of penicillin binding to penicillin-binding proteins of Staphylococcus aureus. Biochem J (1994) 1.28

Crystal structure of a deacylation-defective mutant of penicillin-binding protein 5 at 2.3-A resolution. J Biol Chem (2001) 1.26

Heterogeneously vancomycin-resistant Staphylococcus epidermidis strain causing recurrent peritonitis in a dialysis patient during vancomycin therapy. J Clin Microbiol (1999) 1.13

Crystal structure of wild-type penicillin-binding protein 5 from Escherichia coli: implications for deacylation of the acyl-enzyme complex. J Biol Chem (2003) 1.11

pH, inhibitor, and substrate specificity studies on Escherichia coli penicillin-binding protein 5. Biochim Biophys Acta (2002) 0.95

DSS as an activator of carboxypeptidase A. Biochem Biophys Res Commun (1969) 0.93

Substitution of lysine 213 with arginine in penicillin-binding protein 5 of Escherichia coli abolishes D-alanine carboxypeptidase activity without affecting penicillin binding. J Biol Chem (1992) 0.89

Fluorescent coupled enzyme assays for D-alanine: application to penicillin-binding protein and vancomycin activity assays. Anal Biochem (2000) 0.89

On the relationships between molecular conformation, affinity towards penicillin-binding proteins, and biological activity of penicillin G-sulfoxide. Z Naturforsch C (1989) 0.77

[Methicillin resistant Staphylococcus]. Medicina (B Aires) (2002) 0.76

Articles by these authors

Microdeletion/duplication at 15q13.2q13.3 among individuals with features of autism and other neuropsychiatric disorders. J Med Genet (2008) 3.87

Hyperacute thrombolysis with IV rtPA of acute ischemic stroke: efficacy and safety profile of 54 patients at a tertiary referral center in a developing country. Neurol India (2007) 3.52

Role of auxilin in uncoating clathrin-coated vesicles. Nature (1995) 3.42

Prevalence of anaemia in pregnant & lactating women in India. Indian J Med Res (2006) 3.04

Corticosteroids for acute bacterial meningitis. Cochrane Database Syst Rev (2007) 2.78

Rapid diagnosis of tuberculous meningitis by polymerase chain reaction. Lancet (1991) 2.77

Cardiac fatigue following prolonged endurance exercise of differing distances. Med Sci Sports Exerc (2000) 2.47

Angiotensin-converting-enzyme gene insertion/deletion polymorphism and response to physical training. Lancet (1999) 2.27

Measuring brain natriuretic peptide. Lancet (1996) 2.03

Human gene for physical performance. Nature (1998) 1.78

A conserved clathrin assembly motif essential for synaptic vesicle endocytosis. J Neurosci (2000) 1.75

Corticosteroids in acute bacterial meningitis. Cochrane Database Syst Rev (2003) 1.68

QT dispersion and RR variations on 12-lead ECGs in patients with congestive heart failure secondary to idiopathic dilated cardiomyopathy. Eur Heart J (1996) 1.63

Diagnostic criteria for tuberculous meningitis and their validation. Tuber Lung Dis (1994) 1.54

Disappearing CT lesions in epilepsy: is tuberculosis or cysticercosis the cause? J Neurol Neurosurg Psychiatry (1989) 1.52

Association of angiotensin-converting enzyme gene I/D polymorphism with change in left ventricular mass in response to physical training. Circulation (1997) 1.48

Fragmentation of pulmonary embolus. Lancet (1992) 1.41

Difficulty with a flanged tracheostomy tube. Anaesthesia (2005) 1.39

Chest pain during daily life in patients with hypertrophic cardiomyopathy: an ambulatory electrocardiographic study. Eur Heart J (1996) 1.39

Radioactivity in organs of patients receiving radioisotopes: a retraction. N Engl J Med (1977) 1.38

Diagnostic dilemma in flaccid paralysis following anti-rabies vaccine. Neurol India (2004) 1.37

Regulation of AP-3 function by inositides. Identification of phosphatidylinositol 3,4,5-trisphosphate as a potent ligand. J Biol Chem (1997) 1.33

Hsc70 chaperones clathrin and primes it to interact with vesicle membranes. J Biol Chem (2000) 1.28

Uncoating of clathrin-coated vesicles in presynaptic terminals: roles for Hsc70 and auxilin. Neuron (2001) 1.27

A conserved role for human Nup98 in altering chromatin structure and promoting epigenetic transcriptional memory. PLoS Biol (2013) 1.27

Noninvasive assessment of the digital volume pulse. Comparison with the peripheral pressure pulse. Hypertension (2000) 1.26

Auxilin-induced interaction of the molecular chaperone Hsc70 with clathrin baskets. Biochemistry (1997) 1.24

Clathrin assembly protein AP-3. The identity of the 155K protein, AP 180, and NP185 and demonstration of a clathrin binding domain. J Biol Chem (1991) 1.23

A role for the clathrin assembly domain of AP180 in synaptic vesicle endocytosis. J Neurosci (1999) 1.21

Prospective prognostic assessment of blood pressure response during exercise in patients with hypertrophic cardiomyopathy. Circulation (1997) 1.18

Hematological and molecular response evaluation of CML patients on imatinib. J Assoc Physicians India (2007) 1.17

Lipid peroxidation and activity of antioxidant enzymes in diabetic rats. Mol Cell Biochem (1995) 1.17

Cardiopulmonary effects of diazepam. Clin Pharmacol Ther (1973) 1.17

Clonal complexes and virulence factors of Staphylococcus aureus from several cities in India. BMC Microbiol (2012) 1.14

Increased production of oxygen free radicals in cigarette smokers. Int J Exp Pathol (1991) 1.12

Genotyping of methicillin-resistant Staphylococcus aureus strains from two hospitals in Bangalore, South India. J Clin Microbiol (2005) 1.12

Cerebellar ataxia in systemic lupus erythematosus: three case reports. Ann Rheum Dis (1988) 1.12

AP180 and AP-2 interact directly in a complex that cooperatively assembles clathrin. J Biol Chem (1999) 1.10

Structural and functional characterization of Staphylococcus aureus dihydrodipicolinate synthase. FEBS Lett (2008) 1.10

Plant system: nature's nanofactory. Colloids Surf B Biointerfaces (2009) 1.10

Core safeguards for clinical research with adults who are unable to consent. Ann Intern Med (2001) 1.09

erbB2 expression in breast and other human tumours. J Clin Pathol (1992) 1.09

Increased oxidative stress in rat liver and pancreas during progression of streptozotocin-induced diabetes. Clin Sci (Lond) (1998) 1.09

Intratesticular varicocele: evaluation using conventional and Doppler sonography. AJR Am J Roentgenol (1999) 1.09

Surgical results and complications of mitomycin C-augmented trabeculectomy in refractory developmental glaucoma. Ophthalmic Surg Lasers (1999) 1.08

Deep-etch visualization of 27S clathrin: a tetrahedral tetramer. J Cell Biol (1987) 1.06

Influence of glucose on the transmembrane action potential of papillary muscle. Effects of concentration, phlorizin and insulin, nonmetabolizable sugars, and stimulators of glycolysis. J Gen Physiol (1969) 1.04

Purification and characterization of a molecular weight 100,000 coat protein from coated vesicles obtained from bovine brain. Biochemistry (1986) 1.02

ATPase activity associated with the uncoating of clathrin baskets by Hsp70. J Biol Chem (1994) 1.02

Structural and biochemical bases for the redox sensitivity of Mycobacterium tuberculosis RslA. J Mol Biol (2010) 1.02

Acute inflammatory demyelinating polyneuropathy in patients with pregnancy. Neurol India (2004) 1.01

Epidemic meticillin-resistant Staphylococcus aureus (EMRSA-15) variants detected in healthy and diseased individuals in India. J Med Microbiol (2010) 1.01

Evidence-based management of Mastalgia: a meta-analysis of randomised trials. Breast (2007) 1.01

A conserved function for Arabidopsis SUPERMAN in regulating floral-whorl cell proliferation in rice, a monocotyledonous plant. Curr Biol (2000) 1.00

A study of factors delaying hospital arrival of patients with acute stroke. Neurol India (2001) 0.99

Intra-operative electrocorticography in lesional epilepsy. Epilepsy Res (2010) 0.99

Antioxidant defense system in diabetic kidney: a time course study. Life Sci (1997) 0.98

Planimetric optic disc parameters in normal eyes: a population-based study in South India. Indian J Ophthalmol (2001) 0.98

Staphylococcus aureus eye infections in two Indian hospitals: emergence of ST772 as a major clone. Clin Ophthalmol (2012) 0.98

Structural and biophysical studies on two promoter recognition domains of the extra-cytoplasmic function sigma factor sigma(C) from Mycobacterium tuberculosis. J Biol Chem (2006) 0.98

Community-acquired methicillin-resistant Staphylococcus aureus pyomyositis with myelitis: A rare occurrence with diverse presentation. Neurol India (2009) 0.97

Normobaric oxygen therapy in acute ischemic stroke: A pilot study in Indian patients. Ann Indian Acad Neurol (2010) 0.97

Clathrin and synaptic vesicle endocytosis: studies at the squid giant synapse. Biochem Soc Trans (2006) 0.96

Cerebral venous thrombosis in ulcerative colitis. Neurol India (2002) 0.95

Biosynthesis of silver nanoparticles using Eclipta leaf. Biotechnol Prog (2009) 0.94

Structure and nucleotide specificity of Staphylococcus aureus dihydrodipicolinate reductase (DapB). FEBS Lett (2011) 0.93

Antioxidant enzymes in hypercholesterolemia and effects of vitamin E in rabbits. Atherosclerosis (1993) 0.93

Treating neurocysticercosis medically: a systematic review of randomized, controlled trials. Trop Med Int Health (1999) 0.92

Idiopathic hypertrophic cranial pachymeningitis and dural sinus occlusion: two patients with long-term follow up. J Clin Neurosci (2009) 0.92

Reading between the lines: direct-to-consumer advertising of genetic testing in the USA. Reprod Health Matters (2001) 0.90

Draft genome sequence of Staphylococcus aureus 118 (ST772), a major disease clone from India. J Bacteriol (2012) 0.90

Synthesis of TiO2 nanoparticles using microorganisms. Colloids Surf B Biointerfaces (2009) 0.90

QT dispersion and risk factors for sudden cardiac death in patients with hypertrophic cardiomyopathy. Am J Cardiol (1998) 0.89

Genome sequencing unveils a novel sea enterotoxin-carrying PVL phage in Staphylococcus aureus ST772 from India. PLoS One (2013) 0.88

Effects of plant and animal lipids rich in docosenoic acids on the myocardium of Cynomolgus monkeys. Nutr Metab (1978) 0.88

Time course study of oxidative stress in aorta and heart of diabetic rat. Clin Sci (Lond) (1996) 0.88

Effects of glucose metabolism on the transmembrane action potential and contraction of human papillary muscle during surgical anoxia. Ann Thorac Surg (1969) 0.87

The mechanism of upstream activation in the rrnB operon of Mycobacterium smegmatis is different from the Escherichia coli paradigm. Microbiology (2005) 0.87

Effect of replacement of potassium by rubidium on the transmembrane action potential and contractility of human papillary muscle. Circ Res (1969) 0.87

A high-affinity interaction between NusA and the rrn nut site in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2004) 0.86

Variation in in-patient stroke management in ten centres in different countries: the INCLEN multicentre stroke collaboration. J Neurol Sci (1999) 0.86

Influence of glucose on the transmembrane action potential of guinea-pig papillary muscle. Metabolic inhibitors, ouabain, and calcium chloride, and their interaction with glucose, sympathomimetic amines, and aminophylline. Circ Res (1969) 0.86

Reading between the lines: direct-to-consumer advertising of genetic testing. Hastings Cent Rep (2001) 0.86

Physiological profile and predictors of cycling performance in ultra-endurance triathletes. J Sports Med Phys Fitness (2000) 0.86

A novel type-III staphylococcal cassette chromosome mec (SCCmec) variant among Indian isolates of methicillin-resistant Staphylococcus aureus. FEMS Microbiol Lett (2009) 0.85

A new preference-based analysis for randomized trials can estimate treatment acceptability and effect in compliant patients. J Clin Epidemiol (2006) 0.85

Thermodynamics of target peptide recognition by calmodulin and a calmodulin analogue: implications for the role of the central linker. FEBS Lett (1999) 0.84

Treatment of urethral stones by retrograde manipulation and extracorporeal shock wave lithotripsy. Br J Urol (1995) 0.84

T wave complexity in patients with hypertrophic cardiomyopathy. Pacing Clin Electrophysiol (1998) 0.84

Role of oxyradicals in cardiovascular depression and cellular injury in hemorrhagic shock and reinfusion: effect of SOD and catalase. Circ Shock (1994) 0.84

Pediatric carbamazepine intoxication. Ann Emerg Med (1995) 0.84

Serum antioxidant enzyme activity in Parkinson's disease. Mol Cell Biochem (1992) 0.84

Mechanism of H2O2-induced modulation of airway smooth muscle. Am J Physiol (1992) 0.83

Randomized controlled trial of dexamethasone in tuberculous meningitis. Tuber Lung Dis (1994) 0.83

Oxygen free radicals and cardiac depression. Clin Biochem (1994) 0.83

Addition of a polypeptide stretch at the N-terminus improves the expression, stability and solubility of recombinant protein tyrosine phosphatases from Drosophila melanogaster. Protein Expr Purif (2007) 0.83

Influence of energy supply and calcium on the low sodium induced changes in the transmembrane potential and contraction of guinea pig papillary muscle. Can J Physiol Pharmacol (1970) 0.83

Dexamethasone is not necessarily unsafe in primary supratentorial intracerebral haemorrhage. J Neurol Neurosurg Psychiatry (1998) 0.83