Published in Circulation on October 27, 2009
Pressed for time: the circadian clock and hypertension. J Appl Physiol (1985) (2009) 1.15
Enhancing translation: guidelines for standard pre-clinical experiments in mdx mice. Neuromuscul Disord (2011) 1.08
Tissue-intrinsic dysfunction of circadian clock confers transplant arteriosclerosis. Proc Natl Acad Sci U S A (2011) 0.97
Melanopsin mediates light-dependent relaxation in blood vessels. Proc Natl Acad Sci U S A (2014) 0.82
Circadian clock control of Nox4 and reactive oxygen species in the vasculature. PLoS One (2013) 0.79
Obesity alters the peripheral circadian clock in the aorta and microcirculation. Microcirculation (2015) 0.78
The presence and localization of melatonin receptors in the rat aorta. Cell Mol Neurobiol (2011) 0.78
In cerebrovascular circadian rhythms, EETs keep the beat. Focus on "Rhythmic expression of cytochrome P450 epoxygenases CYP4x1 and CYP2c11 in the rat brain and vasculature". Am J Physiol Cell Physiol (2014) 0.77
Effects of ovarian hormones on internal circadian organization in rats. Biol Reprod (2013) 0.76
Relevance to home blood pressure monitoring protocol of blood pressure measurements taken before first- morning micturition and in the afternoon. Arq Bras Cardiol (2014) 0.75
Eplerenone restores 24-h blood pressure circadian rhythm and reduces advanced glycation end-products in rhesus macaques with spontaneous hypertensive metabolic syndrome. Sci Rep (2016) 0.75
World Congress on the insulin resistance syndrome, 2009: cellular mechanisms of insulin resistance. Diabetes Care (2010) 0.75
Shift work and occupational stress in police officers. Saf Health Work (2014) 0.75
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell (1997) 21.42
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature (1999) 13.73
Obesity and metabolic syndrome in circadian Clock mutant mice. Science (2005) 12.66
PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues. Proc Natl Acad Sci U S A (2004) 12.43
Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science (1997) 11.48
Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature (1999) 11.37
A serum shock induces circadian gene expression in mammalian tissue culture cells. Cell (1998) 10.92
Role of the CLOCK protein in the mammalian circadian mechanism. Science (1998) 10.03
The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator. Cell (2002) 9.92
Mop3 is an essential component of the master circadian pacemaker in mammals. Cell (2000) 8.72
Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus. Genes Dev (2000) 8.19
Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms. Nature (1999) 7.86
Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior. Science (1994) 7.83
Entrainment of the circadian clock in the liver by feeding. Science (2001) 7.09
BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis. PLoS Biol (2004) 6.72
Resetting of circadian time in peripheral tissues by glucocorticoid signaling. Science (2000) 6.55
Circadian gene expression in individual fibroblasts: cell-autonomous and self-sustained oscillators pass time to daughter cells. Cell (2004) 6.44
A functional genomics strategy reveals Rora as a component of the mammalian circadian clock. Neuron (2004) 5.71
Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock. Neuron (2001) 5.36
Post-translational modifications regulate the ticking of the circadian clock. Nat Rev Mol Cell Biol (2007) 5.24
Circadian variation of blood-pressure. Lancet (1978) 5.22
Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau. Science (2000) 4.94
A clock shock: mouse CLOCK is not required for circadian oscillator function. Neuron (2006) 4.91
Intercellular coupling confers robustness against mutations in the SCN circadian clock network. Cell (2007) 4.87
The mPer2 gene encodes a functional component of the mammalian circadian clock. Nature (1999) 4.74
Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2. Proc Natl Acad Sci U S A (1999) 4.62
Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock. Cell (2001) 4.61
Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression. Curr Biol (2004) 4.49
Light-independent role of CRY1 and CRY2 in the mammalian circadian clock. Science (1999) 4.43
The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors. Proc Natl Acad Sci U S A (1998) 4.20
Light-dependent sequestration of TIMELESS by CRYPTOCHROME. Science (1999) 4.09
NPAS2: an analog of clock operative in the mammalian forebrain. Science (2001) 3.88
SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins. Science (2007) 3.59
Molecular mechanisms of the biological clock in cultured fibroblasts. Science (2001) 3.46
The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling. Proc Natl Acad Sci U S A (2000) 3.12
Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis. Proc Natl Acad Sci U S A (2005) 3.12
Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation. Mol Cell Biol (2005) 3.03
CLOCK and NPAS2 have overlapping roles in the suprachiasmatic circadian clock. Nat Neurosci (2007) 2.84
Targeted disruption of the mPer3 gene: subtle effects on circadian clock function. Mol Cell Biol (2000) 2.69
SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein. J Biol Chem (2005) 2.68
Nuclear receptor Rev-erbalpha is a critical lithium-sensitive component of the circadian clock. Science (2006) 2.62
Network features of the mammalian circadian clock. PLoS Biol (2009) 2.59
Regulation of CLOCK and MOP4 by nuclear hormone receptors in the vasculature: a humoral mechanism to reset a peripheral clock. Cell (2001) 2.59
Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon. Mol Cell Biol (2000) 2.52
The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase Iepsilon. J Biol Chem (2002) 2.48
Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice. Science (2006) 2.41
Circadian variation of blood pressure and the vascular response to asynchronous stress. Proc Natl Acad Sci U S A (2007) 2.39
BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system. Genes Dev (2003) 2.37
Glucose down-regulates Per1 and Per2 mRNA levels and induces circadian gene expression in cultured Rat-1 fibroblasts. J Biol Chem (2002) 2.30
Progressive arthropathy in mice with a targeted disruption of the Mop3/Bmal-1 locus. Genesis (2005) 2.30
Dippers and non-dippers. Lancet (1988) 2.28
Altered behavioral rhythms and clock gene expression in mice with a targeted mutation in the Period1 gene. EMBO J (2001) 2.11
Aryl hydrocarbon receptor nuclear translocator-like (BMAL1) is associated with susceptibility to hypertension and type 2 diabetes. Proc Natl Acad Sci U S A (2007) 1.84
Vascular disease in mice with a dysfunctional circadian clock. Circulation (2009) 1.82
Cellular senescence impairs circadian expression of clock genes in vitro and in vivo. Circ Res (2006) 1.68
Vascular PPARgamma controls circadian variation in blood pressure and heart rate through Bmal1. Cell Metab (2008) 1.65
Disrupted fat absorption attenuates obesity induced by a high-fat diet in Clock mutant mice. FEBS Lett (2005) 1.65
Genetic components of the circadian clock regulate thrombogenesis in vivo. Circulation (2008) 1.62
Acute modulation of endothelial Akt/PKB activity alters nitric oxide-dependent vasomotor activity in vivo. J Clin Invest (2000) 1.56
Bioinformatic analysis of circadian gene oscillation in mouse aorta. Circulation (2005) 1.40
Entrainment of human circadian rhythms by light-dark cycles: a reassessment. Photochem Photobiol (1981) 1.39
Mutation of the circadian clock gene Per2 alters vascular endothelial function. Circulation (2007) 1.39
Increased vascular senescence and impaired endothelial progenitor cell function mediated by mutation of circadian gene Per2. Circulation (2008) 1.36
Circadian oscillation of BMAL1, a partner of a mammalian clock gene Clock, in rat suprachiasmatic nucleus. Biochem Biophys Res Commun (1998) 1.36
Regulation of the PAI-1 promoter by circadian clock components: differential activation by BMAL1 and BMAL2. J Mol Cell Cardiol (2003) 1.34
The basic helix-loop-helix-PAS protein MOP9 is a brain-specific heterodimeric partner of circadian and hypoxia factors. J Neurosci (2000) 1.27
CLIF, a novel cycle-like factor, regulates the circadian oscillation of plasminogen activator inhibitor-1 gene expression. J Biol Chem (2000) 1.27
Reduced alpha-adrenoceptor responsiveness and enhanced baroreflex sensitivity in Cry-deficient mice lacking a biological clock. J Physiol (2005) 1.22
The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo. Sci Signal (2009) 1.19
Angiotensin II induces circadian gene expression of clock genes in cultured vascular smooth muscle cells. Circulation (2001) 1.16
Pressed for time: the circadian clock and hypertension. J Appl Physiol (1985) (2009) 1.15
Cardiovascular tissues contain independent circadian clocks. Clin Exp Hypertens (2005) 1.11
Thrombomodulin is a clock-controlled gene in vascular endothelial cells. J Biol Chem (2007) 1.10
Reduced nitric oxide causes age-associated impairment of circadian rhythmicity. Circ Res (2008) 1.06
Phosphatidylinositol 3 kinase-Akt signaling serves as a circadian output in the retina. J Neurochem (2009) 0.97
Peripheral circadian clock rhythmicity is retained in the absence of adrenergic signaling. Arterioscler Thromb Vasc Biol (2007) 0.96
Casein kinase I epsilon associates with and phosphorylates the tight junction protein occludin. FEBS Lett (2006) 0.93
The mortality of MOP3 deficient mice with a systemic functional failure. J Biomed Sci (2006) 0.92
Relationship between physical activity and blood pressure in dipper and non-dipper hypertensive patients. J Hypertens (2002) 0.89
Transient, light-induced rhythmicity in mPer-deficient mice. J Biol Rhythms (2007) 0.87
Resetting of peripheral circadian clock by prostaglandin E2. EMBO Rep (2005) 0.86
Cloning of mouse BMAL2 and its daily expression profile in the suprachiasmatic nucleus: a remarkable acceleration of Bmal2 sequence divergence after Bmal gene duplication. Neurosci Lett (2001) 0.85
Diurnal amplitudes of arterial pressure and heart rate are dampened in Clock mutant mice and adrenalectomized mice. Endocrinology (2008) 0.83
Circadian locomotor analysis of male mice lacking the gene for neuronal nitric oxide synthase (nNOS-/-) J Biol Rhythms (1999) 0.79
Vascular rhythms and adaptation: do your arteries know what time it is? Circulation (2009) 0.78
The resetting of the circadian rhythm by Prostaglandin J2 is distinctly phase-dependent. FEBS Lett (2008) 0.78
Circadian organization in male mice lacking the gene for endothelial nitric oxide synthase (eNOS-/-). J Biol Rhythms (2001) 0.77