Published in Clin Cancer Res on October 27, 2009
The oral cavity contains abundant known and novel human papillomaviruses from the Betapapillomavirus and Gammapapillomavirus genera. J Infect Dis (2011) 1.87
Second primary cancers after an index head and neck cancer: subsite-specific trends in the era of human papillomavirus-associated oropharyngeal cancer. J Clin Oncol (2010) 1.70
Adenosquamous carcinoma of the head and neck: relationship to human papillomavirus and review of the literature. Head Neck Pathol (2011) 1.61
A comparison of clinically utilized human papillomavirus detection methods in head and neck cancer. Mod Pathol (2011) 1.58
A retrospective investigation on canine papillomavirus 1 (CPV1) in oral oncogenesis reveals dogs are not a suitable animal model for high-risk HPV-induced oral cancer. PLoS One (2014) 1.49
Correlation of cellular immunity with human papillomavirus 16 status and outcome in patients with advanced oropharyngeal cancer. Arch Otolaryngol Head Neck Surg (2010) 1.31
Epidemiology and clinical aspects of HPV in head and neck cancers. Head Neck Pathol (2012) 1.29
The clinical impact of HPV tumor status upon head and neck squamous cell carcinomas. Oral Oncol (2013) 1.17
Serum antibodies to the HPV16 proteome as biomarkers for head and neck cancer. Br J Cancer (2011) 1.13
Squamous Cell Carcinoma - Similarities and Differences among Anatomical Sites. Am J Cancer Res (2011) 1.13
Activating transcription factor 3 activates p53 by preventing E6-associated protein from binding to E6. J Biol Chem (2010) 1.12
The head and neck cancer cell oncogenome: a platform for the development of precision molecular therapies. Oncotarget (2014) 1.12
Low-dose cyclophosphamide administered as daily or single dose enhances the antitumor effects of a therapeutic HPV vaccine. Cancer Immunol Immunother (2012) 1.10
Infiltrating lymphocytes and human papillomavirus-16--associated oropharyngeal cancer. Laryngoscope (2012) 1.09
Detection of human papillomavirus (HPV) in clinical samples: evolving methods and strategies for the accurate determination of HPV status of head and neck carcinomas. Oral Oncol (2014) 1.08
Epidemiology of oral human papillomavirus infection. Oral Oncol (2013) 1.07
PePr: a peak-calling prioritization pipeline to identify consistent or differential peaks from replicated ChIP-Seq data. Bioinformatics (2014) 1.04
Evidence for a causal association for HPV in head and neck cancers. Eur Arch Otorhinolaryngol (2011) 1.01
Identification of the Cell-Intrinsic and -Extrinsic Pathways Downstream of EGFR and IFNγ That Induce PD-L1 Expression in Head and Neck Cancer. Cancer Res (2015) 1.01
Frequency and prognostic significance of p16(INK4A) protein overexpression and transcriptionally active human papillomavirus infection in laryngeal squamous cell carcinoma. Br J Cancer (2015) 0.98
Expression of EGFR, VEGF, and NOTCH1 suggest differences in tumor angiogenesis in HPV-positive and HPV-negative head and neck squamous cell carcinoma. Head Neck Pathol (2013) 0.97
Emerging human papillomavirus vaccines. Expert Opin Emerg Drugs (2012) 0.96
Prevalence of human papillomavirus in oropharyngeal squamous cell carcinoma in the United States across time. Chem Res Toxicol (2014) 0.96
Differences in methylation profiles between HPV-positive and HPV-negative oropharynx squamous cell carcinoma: a systematic review. Epigenetics (2013) 0.96
Somatic mutations in the D-loop of mitochondrial DNA in oral squamous cell carcinoma. Eur Arch Otorhinolaryngol (2011) 0.96
Spindle cell carcinomas of the head and neck rarely harbor transcriptionally-active human papillomavirus. Head Neck Pathol (2013) 0.96
Transcriptional profiling by sequencing of oropharyngeal cancer. Mayo Clin Proc (2012) 0.94
Proteomic analysis of oropharyngeal carcinomas reveals novel HPV-associated biological pathways. Int J Cancer (2012) 0.94
Impact of HPV in Oropharyngeal Cancer. J Oncol (2010) 0.93
Innovative DNA vaccine for human papillomavirus (HPV)-associated head and neck cancer. Gene Ther (2010) 0.91
Biology of human papillomavirus-related oropharyngeal cancer. Semin Radiat Oncol (2012) 0.90
Modifiable risk behaviors in patients with head and neck cancer. Cancer (2013) 0.89
The phosphatase and tensin homologue deleted on chromosome 10 mediates radiosensitivity in head and neck cancer. Br J Cancer (2010) 0.89
The sinonasal tract: another potential "hot spot" for carcinomas with transcriptionally-active human papillomavirus. Head Neck Pathol (2013) 0.89
The molecular pathogenesis of head and neck cancer. Cancer Biol Ther (2010) 0.87
Polymorphisms of MDM4 and risk of squamous cell carcinoma of the head and neck. Pharmacogenet Genomics (2011) 0.87
Disruption of HPV16-E7 by CRISPR/Cas system induces apoptosis and growth inhibition in HPV16 positive human cervical cancer cells. Biomed Res Int (2014) 0.87
Involvement of single-nucleotide polymorphisms in predisposition to head and neck cancer in Saudi Arabia. Genet Test Mol Biomarkers (2011) 0.87
Low risk of second primary malignancies among never smokers with human papillomavirus-associated index oropharyngeal cancers. Head Neck (2012) 0.87
Distinct effects of alcohol consumption and smoking on genetic alterations in head and neck carcinoma. PLoS One (2013) 0.87
Recently identified biomarkers that promote lymph node metastasis in head and neck squamous cell carcinoma. Cancers (Basel) (2011) 0.86
Gα₁₂ drives invasion of oral squamous cell carcinoma through up-regulation of proinflammatory cytokines. PLoS One (2013) 0.86
Psychological factors associated with head and neck cancer treatment and survivorship: evidence and opportunities for behavioral medicine. J Consult Clin Psychol (2012) 0.85
p53 in head and neck cancer: functional consequences and environmental implications of TP53 mutations. Head Neck Oncol (2010) 0.85
Dendritic Cells (DC) Facilitate Detachment of Squamous Carcinoma Cells (SCC), While SCC Promote an Immature CD16(+) DC Phenotype and Control DC Migration. Cancer Microenviron (2011) 0.85
Prevalence and predictive role of p16 and epidermal growth factor receptor in surgically treated oropharyngeal and oral cavity cancer. Head Neck (2012) 0.85
HPV in oropharyngeal cancer: the basics to know in clinical practice. Acta Otorhinolaryngol Ital (2014) 0.85
Detection of oral human papillomavirus in HIV-positive men who have sex with men 3 years after baseline: a follow up cross-sectional study. PLoS One (2014) 0.84
High XRCC1 protein expression is associated with poorer survival in patients with head and neck squamous cell carcinoma. Clin Cancer Res (2011) 0.84
Frequency and genotype of human papillomavirus among Sudanese patients with head and neck tumours. Ecancermedicalscience (2012) 0.84
Emerging strategies for the early detection and prevention of head and neck squamous cell cancer. J Cell Physiol (2012) 0.83
Telomere length in peripheral blood lymphocytes contributes to the development of HPV-associated oropharyngeal carcinoma. Cancer Res (2013) 0.82
Is human papillomavirus involved in laryngeal neuroendocrine carcinoma? Eur Arch Otorhinolaryngol (2012) 0.82
Initial evidence for Sec62 as a prognostic marker in advanced head and neck squamous cell carcinoma. Oncol Lett (2016) 0.81
Nuclear epidermal growth factor receptor and p16 expression in head and neck squamous cell carcinoma. Laryngoscope (2012) 0.81
Human papillomavirus, p16, and epidermal growth factor receptor biomarkers and CT perfusion values in head and neck squamous cell carcinoma. AJNR Am J Neuroradiol (2013) 0.81
Inhibition of p53 by adenovirus type 12 E1B-55K deregulates cell cycle control and sensitizes tumor cells to genotoxic agents. J Virol (2011) 0.81
The role of sexual behavior in head and neck cancer: implications for prevention and therapy. Expert Rev Anticancer Ther (2014) 0.81
Do 18F-FDG PET/CT parameters in oropharyngeal and oral cavity squamous cell carcinomas indicate HPV status? Clin Nucl Med (2015) 0.80
HPV Positive Head and Neck Cancers: Molecular Pathogenesis and Evolving Treatment Strategies. Cancers (Basel) (2016) 0.80
Human papillomavirus infection and immunohistochemical expression of cell cycle proteins pRb, p53, and p16(INK4a) in sinonasal diseases. Infect Agent Cancer (2015) 0.79
Different protein expression associated with chemotherapy response in oropharyngeal cancer according to HPV status. BMC Cancer (2014) 0.79
Human papillomavirus type 16 E7 oncoprotein mediates CCNA1 promoter methylation. Cancer Sci (2015) 0.78
Reduced impact of nodal metastases as a prognostic factor for tonsil cancer in the HPV era. Eur Arch Otorhinolaryngol (2013) 0.78
p21 suppresses inflammation and tumorigenesis on pRB-deficient stratified epithelia. Oncogene (2013) 0.78
Retrospective analysis of the impact of HPV status and smoking on mucositis in patients with oropharyngeal squamous cell carcinoma treated with concurrent chemotherapy and radiotherapy. Oral Oncol (2014) 0.78
Epigenetic impact of infection on carcinogenesis: mechanisms and applications. Genome Med (2016) 0.78
Psychosocial functioning and vascular endothelial growth factor in patients with head and neck cancer. Head Neck (2013) 0.77
Molecular analyses of unselected head and neck cancer cases demonstrates that human papillomavirus transcriptional activity is positively associated with survival and prognosis. BMC Cancer (2016) 0.77
Impact of somatic mutations in the D-loop of mitochondrial DNA on the survival of oral squamous cell carcinoma patients. PLoS One (2015) 0.77
Molecular genetic characterization of p53 mutated oropharyngeal squamous cell carcinoma cells transformed with human papillomavirus E6 and E7 oncogenes. Int J Oncol (2013) 0.77
Clinical features and treatment strategy for HPV-related oropharyngeal cancer. Int J Clin Oncol (2016) 0.77
Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx. J Clin Oncol (2016) 0.76
Human papillomavirus 16 (HPV16) enhances tumor growth and cancer stemness of HPV-negative oral/oropharyngeal squamous cell carcinoma cells via miR-181 regulation. Papillomavirus Res (2015) 0.76
Proteomic study of HPV-positive head and neck cancers: preliminary results. Biomed Res Int (2014) 0.76
Surgically treated oropharyngeal cancer: risk factors and tumor characteristics. J Cancer Res Clin Oncol (2014) 0.76
Comparative analysis of HPV16 gene expression profiles in cervical and in oropharyngeal squamous cell carcinoma. Oncotarget (2017) 0.75
Human Papilloma Virus in Oral Cavity Cancer and Relation to Change in Quality of Life Following Treatment-a Pilot Study from Northern India. Indian J Surg Oncol (2016) 0.75
Apoptotic capacity and risk of squamous cell carcinoma of the head and neck. Eur J Cancer (2016) 0.75
Tumor volume as a predictor of survival in human papillomavirus-positive oropharyngeal cancer. Head Neck (2015) 0.75
From novel insights in molecular biology to targeted treatment approaches in head and neck cancer. EJC Suppl (2013) 0.75
Current role of human papillomavirus in head and neck oncology. EJC Suppl (2013) 0.75
Molecular Probing of the HPV-16 E6 Protein Alpha Helix Binding Groove with Small Molecule Inhibitors. PLoS One (2016) 0.75
Interferon Inducible IFI16 Expression in p16 Positive Squamous Cell Carcinoma of the Oropharynx. ISRN Otolaryngol (2013) 0.75
Assessing p16 Status of Oropharyngeal Squamous Cell Carcinoma by Combined Assessment of the Number of Cells Stained and the Confluence of p16 Staining: A Validation by Clinical Outcomes. Am J Surg Pathol (2016) 0.75
Modeling head and neck cancer stem cell-mediated tumorigenesis. Cell Mol Life Sci (2016) 0.75
Stress-triggered atavistic reprogramming (STAR) addiction: driving force behind head and neck cancer? Am J Cancer Res (2016) 0.75
Mucosal Alpha-Papillomavirus (HPV89) in a rare skin lesion. Virol J (2015) 0.75
Bax and Bak expression in cervical smears of women with low-and high-risk HPV types: A study of 120 cases. J Cytol (2016) 0.75
Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med (2010) 22.74
Case-control study of human papillomavirus and oropharyngeal cancer. N Engl J Med (2007) 16.39
Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial. J Natl Cancer Inst (2008) 12.77
Human papillomavirus and rising oropharyngeal cancer incidence in the United States. J Clin Oncol (2011) 12.10
Incidence trends for human papillomavirus-related and -unrelated oral squamous cell carcinomas in the United States. J Clin Oncol (2008) 7.97
Randomized phase III trial of concurrent accelerated radiation plus cisplatin with or without cetuximab for stage III to IV head and neck carcinoma: RTOG 0522. J Clin Oncol (2014) 5.80
Oral sexual behaviors associated with prevalent oral human papillomavirus infection. J Infect Dis (2009) 5.24
Detection of human papillomavirus in cervical lymph nodes: a highly effective strategy for localizing site of tumor origin. Clin Cancer Res (2003) 3.42
Oral human papillomavirus infection in adults is associated with sexual behavior and HIV serostatus. J Infect Dis (2004) 3.04
Worldwide trends in incidence rates for oral cavity and oropharyngeal cancers. J Clin Oncol (2013) 3.00
Clinical implications of human papillomavirus in head and neck cancers. J Clin Oncol (2006) 2.91
Burden of potentially human papillomavirus-associated cancers of the oropharynx and oral cavity in the US, 1998-2003. Cancer (2008) 2.67
Head and neck squamous cell cancer and the human papillomavirus: summary of a National Cancer Institute State of the Science Meeting, November 9-10, 2008, Washington, D.C. Head Neck (2009) 2.59
Six-month natural history of oral versus cervical human papillomavirus infection. Int J Cancer (2007) 2.37
Validation of methods for oropharyngeal cancer HPV status determination in US cooperative group trials. Am J Surg Pathol (2012) 1.96
Risk factors for acquisition and clearance of oral human papillomavirus infection among HIV-infected and HIV-uninfected adults. Am J Epidemiol (2014) 1.88
Oral human papillomavirus infection before and after treatment for human papillomavirus 16-positive and human papillomavirus 16-negative head and neck squamous cell carcinoma. Clin Cancer Res (2008) 1.85
Low etiologic fraction for high-risk human papillomavirus in oral cavity squamous cell carcinomas. Oral Oncol (2012) 1.81
Risk factors for oral HPV infection among a high prevalence population of HIV-positive and at-risk HIV-negative adults. Cancer Epidemiol Biomarkers Prev (2011) 1.68
Delayed diagnosis and elevated mortality in an urban population with HIV and lung cancer: implications for patient care. J Acquir Immune Defic Syndr (2006) 1.66
Head and neck cancers. J Natl Compr Canc Netw (2011) 1.64
Assessment of human papillomavirus in lung tumor tissue. J Natl Cancer Inst (2011) 1.59
Real-time quantitative PCR demonstrates low prevalence of human papillomavirus type 16 in premalignant and malignant lesions of the oral cavity. Clin Cancer Res (2002) 1.53
The prevalence and incidence of oral human papillomavirus infection among young men and women, aged 18-30 years. Sex Transm Dis (2012) 1.51
Detection of human papillomavirus-16 in fine-needle aspirates to determine tumor origin in patients with metastatic squamous cell carcinoma of the head and neck. Clin Cancer Res (2007) 1.48
Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res (2013) 1.47
Head and neck cancers, Version 2.2014. Clinical practice guidelines in oncology. J Natl Compr Canc Netw (2014) 1.39
Natural history of anal vs oral HPV infection in HIV-infected men and women. J Infect Dis (2013) 1.37
Gender differences in sexual biomarkers and behaviors associated with human papillomavirus-16, -18, and -33 seroprevalence. Sex Transm Dis (2004) 1.36
Head and neck cancers, version 2.2013. Featured updates to the NCCN guidelines. J Natl Compr Canc Netw (2013) 1.35
Human papillomavirus in HNSCC: recognition of a distinct disease type. Hematol Oncol Clin North Am (2008) 1.28
Associations between oral HPV16 infection and cytopathology: evaluation of an oropharyngeal "pap-test equivalent" in high-risk populations. Cancer Prev Res (Phila) (2011) 1.27
Human papillomavirus and prognosis of oropharyngeal squamous cell carcinoma: implications for clinical research in head and neck cancers. J Clin Oncol (2006) 1.18
Chapter 16: HPV vaccines in immunocompromised women and men. Vaccine (2006) 1.16
Automated high throughput DNA isolation for detection of human papillomavirus in oral rinse samples. J Clin Virol (2011) 1.14
No role for human papillomavirus in esophageal squamous cell carcinoma in China. Int J Cancer (2010) 1.06
Comprehensive control of human papillomavirus infections and related diseases. Vaccine (2013) 1.02
The fanconi anemia pathway limits human papillomavirus replication. J Virol (2012) 1.01
Development of HPV vaccines for HPV-associated head and neck squamous cell carcinoma. Crit Rev Oral Biol Med (2003) 1.01
Prevalence of cervical and oral human papillomavirus infections among US women. J Infect Dis (2013) 0.99
Moderate predictive value of demographic and behavioral characteristics for a diagnosis of HPV16-positive and HPV16-negative head and neck cancer. Oral Oncol (2009) 0.97
A new link between Fanconi anemia and human papillomavirus-associated malignancies. J Natl Cancer Inst (2003) 0.96
Elective versus Therapeutic Neck Dissection in Oral Cancer. N Engl J Med (2015) 0.92
Mucosal melanoma of the head and neck. J Natl Compr Canc Netw (2012) 0.89
A longitudinal study of human papillomavirus 16 L1, e6, and e7 seropositivity and oral human papillomavirus 16 infection. Sex Transm Dis (2015) 0.89
Smokeless Tobacco Use and the Risk of Head and Neck Cancer: Pooled Analysis of US Studies in the INHANCE Consortium. Am J Epidemiol (2016) 0.81
Behavioral, immunologic, and virologic correlates of oral human papillomavirus infection in HIV-infected youth. Sex Transm Dis (2015) 0.80
Human papillomavirus-16 associated adenocarcinoma NOS of base of tongue. Head Neck Pathol (2012) 0.77