Published in J Neuroimmune Pharmacol on November 06, 2009
Long non-coding RNAs in nervous system function and disease. Brain Res (2010) 2.53
Teriflunomide and its mechanism of action in multiple sclerosis. Drugs (2014) 1.08
Brain atrophy correlates with functional outcome in a murine model of multiple sclerosis. Neuroimage (2010) 0.97
Immunology in the clinic review series; focus on type 1 diabetes and viruses: the innate immune response to enteroviruses and its possible role in regulating type 1 diabetes. Clin Exp Immunol (2012) 0.94
Theiler's virus infection: Pathophysiology of demyelination and neurodegeneration. Pathophysiology (2011) 0.91
Long Non-Coding RNAs: The Key Players in Glioma Pathogenesis. Cancers (Basel) (2015) 0.87
Immunopathological patterns from EAE and Theiler's virus infection: Is multiple sclerosis a homogenous 1-stage or heterogenous 2-stage disease? Pathophysiology (2012) 0.85
Transcriptomic meta-analysis of multiple sclerosis and its experimental models. PLoS One (2014) 0.85
Kallikrein 6 regulates early CNS demyelination in a viral model of multiple sclerosis. Brain Pathol (2012) 0.85
Clearance of virus infection from the CNS. Curr Opin Virol (2011) 0.83
New aspects of the pathogenesis of canine distemper leukoencephalitis. Viruses (2014) 0.83
Th17-biased RORγt transgenic mice become susceptible to a viral model for multiple sclerosis. Brain Behav Immun (2014) 0.83
Infections, inflammation and epilepsy. Acta Neuropathol (2015) 0.82
Contrasting roles for CD4 vs. CD8 T-cells in a murine model of virally induced "T1 black hole" formation. PLoS One (2012) 0.82
PDE7 inhibitor TC3.6 ameliorates symptomatology in a model of primary progressive multiple sclerosis. Br J Pharmacol (2015) 0.77
Differential expression of multiple kallikreins in a viral model of multiple sclerosis points to unique roles in the innate and adaptive immune response. Biol Chem (2014) 0.77
Viral infections of the central nervous system: pathogenesis to therapeutics. J Neuroimmune Pharmacol (2010) 0.77
Mechanisms and pharmacology of neuropathic pain in multiple sclerosis. Curr Top Behav Neurosci (2014) 0.76
Role of γδ T cells in antibody production and recovery from SFV demyelinating disease. J Neuroimmunol (2011) 0.76
Roles of regulatory T cells and IL-10 in virus-induced demyelination. J Neuroimmunol (2017) 0.76
Neuropathogenesis of Zika Virus Infection : Potential Roles of Antibody-Mediated Pathology. Acta Med Kinki Univ (2016) 0.75
Theiler's murine encephalomyelitis virus infection of SJL/J and C57BL/6J mice: Models for multiple sclerosis and epilepsy. J Neuroimmunol (2017) 0.75
Immunization with structural and non-structural proteins of Theiler's murine encephalomyelitis virus alters demyelinating disease. J Neurovirol (2012) 0.75
In Silico Perspectives on the Prediction of the PLP's Epitopes involved in Multiple Sclerosis. Iran J Biotechnol (2017) 0.75
Pathogen recognition and innate immunity. Cell (2006) 44.14
Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer (1972) 35.74
Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature (1998) 9.77
SPONTANEOUS ENCEPHALOMYELITIS OF MICE--A NEW VIRUS DISEASE. Science (1934) 9.02
Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis. N Engl J Med (2005) 7.54
Theiler's virus infection in mice: an unusual biphasic disease process leading to demyelination. Infect Immun (1975) 7.12
Progressive multifocal leukoencephalopathy in a patient treated with natalizumab. N Engl J Med (2005) 7.04
Natalizumab for active Crohn's disease. N Engl J Med (2003) 6.44
Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease. N Engl J Med (2005) 6.33
B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells. J Immunol (1986) 6.16
SPONTANEOUS ENCEPHALOMYELITIS OF MICE, A NEW VIRUS DISEASE. J Exp Med (1937) 6.04
A controlled trial of natalizumab for relapsing multiple sclerosis. N Engl J Med (2003) 5.77
Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs. J Immunol (2004) 5.15
Persistent infection with Theiler's virus leads to CNS autoimmunity via epitope spreading. Nat Med (1997) 3.46
Primary demyelination in Theiler's virus infection. An ultrastructural study. Lab Invest (1975) 3.45
No one is naive: the significance of heterologous T-cell immunity. Nat Rev Immunol (2002) 3.20
Poliovirus neutralization by antibodies to internal epitopes of VP4 and VP1 results from reversible exposure of these sequences at physiological temperature. J Virol (1994) 2.90
Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation. Brain (2000) 2.90
Observations on encephalomyelitis of mice (DA strain). J Exp Med (1952) 2.68
Axonal changes in chronic demyelinated cervical spinal cord plaques. Brain (2000) 2.28
Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time. Brain (2002) 2.27
Susceptibility to Theiler's virus-induced demyelination. Mapping of the gene within the H-2D region. J Exp Med (1986) 2.18
Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease in mice is influenced by the H-2D region: correlation with TEMV-specific delayed-type hypersensitivity. J Immunol (1985) 2.06
Theiler's virus infection of beta 2-microglobulin-deficient mice. J Virol (1993) 2.04
Stability and diversity of T cell receptor repertoire usage during lymphocytic choriomeningitis virus infection of mice. J Exp Med (1998) 1.93
Toll-like receptors in central nervous system glial inflammation and homeostasis. J Neurosci Res (2006) 1.91
Private specificities of CD8 T cell responses control patterns of heterologous immunity. J Exp Med (2005) 1.85
Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity. Proc Natl Acad Sci U S A (1993) 1.84
New insights into progressive multifocal leukoencephalopathy. Curr Opin Neurol (2004) 1.78
Two models for multiple sclerosis: experimental allergic encephalomyelitis and Theiler's murine encephalomyelitis virus. J Neuropathol Exp Neurol (1996) 1.67
DA strain of Theiler's murine encephalomyelitis virus induces demyelination in nude mice. Ann Neurol (1984) 1.62
Mechanism of Theiler's virus-induced demyelination in nude mice. Lab Invest (1986) 1.53
Axonal loss in normal-appearing white matter in a patient with acute MS. Neurology (2001) 1.53
Absence of neurological deficits following extensive demyelination in a class I-deficient murine model of multiple sclerosis. Nat Med (1998) 1.49
TLR7: A new sensor of viral infection. Proc Natl Acad Sci U S A (2004) 1.49
FVB mice transgenic for the H-2Db gene become resistant to persistent infection by Theiler's virus. J Virol (1994) 1.48
Consequences of cytotoxic T lymphocyte interaction with major histocompatibility complex class I-expressing neurons in vivo. J Exp Med (1995) 1.44
Detection of Theiler's virus RNA in mouse central nervous system by in situ hybridization. Lab Invest (1981) 1.43
Apoptosis in acute and chronic central nervous system disease induced by Theiler's murine encephalomyelitis virus. Virology (1997) 1.41
Borna disease, a progressive meningoencephalomyelitis as a model for CD4+ T cell-mediated immunopathology in the brain. J Exp Med (1989) 1.39
Alteration of amino acid 101 within capsid protein VP-1 changes the pathogenicity of Theiler's murine encephalomyelitis virus. J Exp Med (1989) 1.39
Axonal injury heralds virus-induced demyelination. Am J Pathol (2003) 1.38
Origins of the T(H)1-T(H)2 model: a personal perspective. Nat Immunol (2006) 1.38
Theiler's virus and Mengo virus induce cross-reactive cytotoxic T lymphocytes restricted to the same immunodominant VP2 epitope in C57BL/6 mice. J Virol (1997) 1.36
Survival of athymic (nu/nu) mice after Theiler's murine encephalomyelitis virus infection by passive administration of neutralizing monoclonal antibody. J Virol (1989) 1.35
Direct activation of innate and antigen-presenting functions of microglia following infection with Theiler's virus. J Virol (2001) 1.34
Trypsin-sensitive neutralization site on VP1 of Theiler's murine encephalomyelitis viruses. J Virol (1988) 1.31
Minus-strand RNA synthesis in the spinal cords of mice persistently infected with Theiler's virus. J Virol (1988) 1.30
CD4(+) and CD8(+) T cells make discrete contributions to demyelination and neurologic disease in a viral model of multiple sclerosis. J Virol (1998) 1.27
Inside-Out versus Outside-In models for virus induced demyelination: axonal damage triggering demyelination. Springer Semin Immunopathol (2002) 1.24
Immunology. After the toll rush. Science (2004) 1.22
Microarray analysis identifies an aberrant expression of apoptosis and DNA damage-regulatory genes in multiple sclerosis. Neurobiol Dis (2005) 1.20
Preservation of motor function by inhibition of CD8+ virus peptide-specific T cells in Theiler's virus infection. FASEB J (2001) 1.19
Apoptosis of hippocampal pyramidal neurons is virus independent in a mouse model of acute neurovirulent picornavirus infection. Am J Pathol (2009) 1.19
A predominant viral epitope recognized by T cells from the periphery and demyelinating lesions of SJL/J mice infected with Theiler's virus is located within VP1(233-244). J Immunol (1994) 1.18
Virus-specific intracytoplasmic inclusions in mouse brain produced by a newly isolated strain of Theiler virus. I. Virologic and morphologic studies. Lab Invest (1977) 1.18
Antibody association with a novel model for primary progressive multiple sclerosis: induction of relapsing-remitting and progressive forms of EAE in H2s mouse strains. Brain Pathol (2000) 1.17
H-2 Dd transgene suppresses Theiler's virus-induced demyelination in susceptible strains of mice. J Neurovirol (1995) 1.16
The majority of infiltrating CD8+ T cells in the central nervous system of susceptible SJL/J mice infected with Theiler's virus are virus specific and fully functional. J Virol (2002) 1.16
Brain-infiltrating cytolytic T lymphocytes specific for Theiler's virus recognize H2Db molecules complexed with a viral VP2 peptide lacking a consensus anchor residue. J Virol (1997) 1.14
A gene affecting Wallerian nerve degeneration maps distally on mouse chromosome 4. Proc Natl Acad Sci U S A (1993) 1.12
Schwann cell remyelination and recurrent demyelination in the central nervous system of mice infected with attenuated Theiler's virus. Am J Pathol (1980) 1.12
Dendritic and synaptic pathology in experimental autoimmune encephalomyelitis. Am J Pathol (2003) 1.11
Gray matter pathology in (chronic) MS: modern views on an early observation. J Neurol Sci (2009) 1.11
High numbers of viral RNA copies in the central nervous system of mice during persistent infection with Theiler's virus. J Virol (2001) 1.10
CD8-deficient SJL mice display enhanced susceptibility to Theiler's virus infection and increased demyelinating pathology. J Neurovirol (2001) 1.10
T-cell-mediated disruption of the neuronal microtubule network: correlation with early reversible axonal dysfunction in acute experimental autoimmune encephalomyelitis. Am J Pathol (2006) 1.09
Monoclonal antibody to Theiler's murine encephalomyelitis virus defines a determinant on myelin and oligodendrocytes, and augments demyelination in experimental allergic encephalomyelitis. J Exp Med (1990) 1.08
A comparative study of acute and chronic diseases induced by two subgroups of Theiler's murine encephalomyelitis virus. Acta Neuropathol (1996) 1.08
Distinct roles for IP-10/CXCL10 in three animal models, Theiler's virus infection, EAE, and MHV infection, for multiple sclerosis: implication of differing roles for IP-10. Mult Scler (2004) 1.08
Putting magnetic resonance spectroscopy studies in context: axonal damage and disability in multiple sclerosis. Semin Neurol (1998) 1.08
Antiapoptotic activity of the cardiovirus leader protein, a viral "security" protein. J Virol (2009) 1.07
Evolution of virulence in picornaviruses. Curr Top Microbiol Immunol (2006) 1.07
Capsid-specific cytotoxic T lymphocytes recognize three distinct H-2D(b)-restricted regions of the BeAn strain of Theiler's virus and exhibit different cytokine profiles. J Virol (2002) 1.07
Identification of a major T-cell epitope within VP3 amino acid residues 24 to 37 of Theiler's virus in demyelination-susceptible SJL/J mice. J Virol (1995) 1.07
A cannabinoid agonist interferes with the progression of a chronic model of multiple sclerosis by downregulating adhesion molecules. Mol Cell Neurosci (2008) 1.07
Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. III. Failure of neuroantigen-specific immune tolerance to affect the clinical course of demyelination. J Neuroimmunol (1990) 1.06
Monoclonal antibody defines determinant between Theiler's virus and lipid-like structures. J Neuroimmunol (1988) 1.05
JC virus induces a vigorous CD8+ cytotoxic T cell response in multiple sclerosis patients. J Neuroimmunol (2006) 1.05
Exacerbation of viral and autoimmune animal models for multiple sclerosis by bacterial DNA. Brain Pathol (1999) 1.04
Analysis of antibody responses to predominant linear epitopes of Theiler's murine encephalomyelitis virus. J Virol (1994) 1.04
Targeting inflammatory demyelinating lesions to sites of Wallerian degeneration. Am J Pathol (2007) 1.03
Grey matter abnormalities in multiple sclerosis: proton magnetic resonance spectroscopic imaging. Mult Scler (2001) 1.02
Apoptotic cells, including macrophages, are prominent in Theiler's virus-induced inflammatory, demyelinating lesions. J Virol (2003) 1.00
Humanization of a mouse antibody against human alpha-4 integrin: a potential therapeutic for the treatment of multiple sclerosis. Hum Antibodies (1997) 1.00
Role of individual T-cell epitopes of Theiler's virus in the pathogenesis of demyelination correlates with the ability to induce a Th1 response. J Virol (1998) 0.99
Induction of autoreactive CD8+ cytotoxic T cells during Theiler's murine encephalomyelitis virus infection: implications for autoimmunity. J Virol (2002) 0.97
Central nervous system pathology caused by autoreactive CD8+ T-cell clones following virus infection. J Virol (2005) 0.96
The pathologic role for COX-2 in apoptotic oligodendrocytes in virus induced demyelinating disease: implications for multiple sclerosis. J Neuroimmunol (2006) 0.96
Preservation of neurologic function during inflammatory demyelination correlates with axon sparing in a mouse model of multiple sclerosis. Neuroscience (2002) 0.95
Detection of tissue culture-adapted Theiler's virus RNA in spinal cord white matter cells throughout infection. Infect Immun (1982) 0.95
Massive apoptosis in lymphoid organs in animal models for primary and secondary progressive multiple sclerosis. Am J Pathol (2005) 0.94
Abnormalities in normal appearing tissues in early primary progressive multiple sclerosis and their relation to disability: a tissue specific magnetisation transfer study. J Neurol Neurosurg Psychiatry (2006) 0.92
Direct comparison of demyelinating disease induced by the Daniel's strain and BeAn strain of Theiler's murine encephalomyelitis virus. Brain Pathol (2003) 0.92
Microorganisms and autoimmunity: making the barren field fertile? Nat Rev Microbiol (2003) 1.76
Axonal injury heralds virus-induced demyelination. Am J Pathol (2003) 1.38
Molecular mimicry as a mechanism of autoimmune disease. Clin Rev Allergy Immunol (2012) 1.37
Autistic disorder and viral infections. J Neurovirol (2005) 1.33
Seizures following picornavirus infection. Epilepsia (2008) 1.31
Innate but not adaptive immune responses contribute to behavioral seizures following viral infection. Epilepsia (2009) 1.26
Inside-Out versus Outside-In models for virus induced demyelination: axonal damage triggering demyelination. Springer Semin Immunopathol (2002) 1.24
Pathogenic epitopes, heterologous immunity and vaccine design. Nat Rev Microbiol (2007) 1.24
Interleukin-6, produced by resident cells of the central nervous system and infiltrating cells, contributes to the development of seizures following viral infection. J Virol (2011) 1.22
Inflammation, demyelination, neurodegeneration and neuroprotection in the pathogenesis of multiple sclerosis. J Neuroimmunol (2006) 1.16
Development of postinfection epilepsy after Theiler's virus infection of C57BL/6 mice. J Neuropathol Exp Neurol (2010) 1.14
Distinct roles for IP-10/CXCL10 in three animal models, Theiler's virus infection, EAE, and MHV infection, for multiple sclerosis: implication of differing roles for IP-10. Mult Scler (2004) 1.08
Theiler's virus infection chronically alters seizure susceptibility. Epilepsia (2009) 1.05
Multiple sclerosis and virus induced immune responses: autoimmunity can be primed by molecular mimicry and augmented by bystander activation. Autoimmunity (2006) 1.04
Targeting inflammatory demyelinating lesions to sites of Wallerian degeneration. Am J Pathol (2007) 1.03
T cell infiltration is associated with increased Lyme arthritis in TLR2-/- mice. FEMS Immunol Med Microbiol (2007) 1.01
Molecular mimicry in multiple sclerosis. Int Rev Neurobiol (2007) 0.98
Infiltrating macrophages are key to the development of seizures following virus infection. J Virol (2012) 0.98
Induction of autoreactive CD8+ cytotoxic T cells during Theiler's murine encephalomyelitis virus infection: implications for autoimmunity. J Virol (2002) 0.97
The pathologic role for COX-2 in apoptotic oligodendrocytes in virus induced demyelinating disease: implications for multiple sclerosis. J Neuroimmunol (2006) 0.96
Central nervous system pathology caused by autoreactive CD8+ T-cell clones following virus infection. J Virol (2005) 0.96
Diffusion basis spectrum imaging detects and distinguishes coexisting subclinical inflammation, demyelination and axonal injury in experimental autoimmune encephalomyelitis mice. NMR Biomed (2014) 0.96
Studies in the modulation of experimental autoimmune encephalomyelitis. J Neuroimmune Pharmacol (2010) 0.95
Massive apoptosis in lymphoid organs in animal models for primary and secondary progressive multiple sclerosis. Am J Pathol (2005) 0.94
Role for complement in the development of seizures following acute viral infection. J Virol (2010) 0.94
Contrasting roles for axonal degeneration in an autoimmune versus viral model of multiple sclerosis: When can axonal injury be beneficial? Am J Pathol (2007) 0.92
Role of CD5+ B-1 cells in EAE pathogenesis. Autoimmunity (2008) 0.92
Experimental autoimmune encephalomyelitis as a testing paradigm for adjuvants and vaccines. Vaccine (2010) 0.91
TGF-beta1 suppresses T cell infiltration and VP2 puff B mutation enhances apoptosis in acute polioencephalitis induced by Theiler's virus. J Neuroimmunol (2007) 0.91
Once initiated, viral encephalitis-induced seizures are consistent no matter the treatment or lack of interleukin-6. J Neurovirol (2011) 0.91
Hyperserotoninemia and altered immunity in autism. J Autism Dev Disord (2006) 0.90
Multiple sclerosis: autoimmunity and viruses. Curr Opin Rheumatol (2013) 0.89
Modulation of experimental autoimmune encephalomyelitis by VLA-2 blockade. Brain Pathol (2007) 0.89
Regulatory role of CD1d in neurotropic virus infection. J Virol (2008) 0.87
Converting relapsing remitting to secondary progressive experimental allergic encephalomyelitis (EAE) by ultraviolet B irradiation. J Neuroimmunol (2004) 0.87
Potential triggers of MS. Results Probl Cell Differ (2010) 0.87
IFN-gamma production and astrocyte recognition by autoreactive T cells induced by Theiler's virus infection: role of viral strains and capsid proteins. J Neuroimmunol (2005) 0.87
Investigation of treatment failure in neonatal echovirus 7 infection. Pediatr Infect Dis J (2006) 0.86
Human T cell expansion and experimental autoimmune encephalomyelitis inhibited by Lenaldekar, a small molecule discovered in a zebrafish screen. J Neuroimmunol (2012) 0.86
Are there enhanced MBP autoantibodies in autism? J Autism Dev Disord (2007) 0.86
Neurotropic viral infections leading to epilepsy: focus on Theiler's murine encephalomyelitis virus. Future Virol (2011) 0.85
Sequential polymicrobial infections lead to CNS inflammatory disease: possible involvement of bystander activation in heterologous immunity. J Neuroimmunol (2007) 0.84
How relevant are GFAP autoantibodies in autism and Tourette Syndrome? J Autism Dev Disord (2007) 0.83
Lack of correlation of central nervous system inflammation and neuropathology with the development of seizures following acute virus infection. J Virol (2011) 0.83
Modulation of immune system function by measles virus infection. II. Infection of B cells leads to the production of a soluble factor that arrests uninfected B cells in G0/G1. Viral Immunol (2003) 0.82
Role of pathogens in multiple sclerosis. Int Rev Immunol (2013) 0.82
Mutation in loop I of VP1 of Theiler's virus delays viral RNA release into cells and enhances antibody-mediated neutralization: a mechanism for the failure of persistence by the mutant virus. J Neurovirol (2002) 0.82
Role for antibodies in altering behavior and movement. Autism Res (2010) 0.81
Monoclonal MOG-reactive autoantibody from progressive EAE has the characteristics of a natural antibody. J Neuroimmunol (2006) 0.81
Targeting myelin proteolipid protein to the MHC class I pathway by ubiquitination modulates the course of experimental autoimmune encephalomyelitis. J Neuroimmunol (2008) 0.80
Neurons tame T cells. Nat Med (2006) 0.79
Infectious RNA isolated from the spinal cords of mice chronically infected with Theiler's murine encephalomyelitis virus. J Virol (2006) 0.79
Polyreactive myelin oligodendrocyte glycoprotein antibodies: Implications for systemic autoimmunity in progressive experimental autoimmune encephalomyelitis. J Neuroimmunol (2007) 0.79
Theiler's murine encephalomyelitis virus attachment to the gastrointestinal tract is associated with sialic acid binding. J Neurovirol (2008) 0.79
Antiviral CD8⁺ T cells cause an experimental autoimmune encephalomyelitis-like disease in naive mice. J Neurovirol (2012) 0.79
The activity within the CA3 excitatory network during Theiler's virus encephalitis is distinct from that observed during chronic epilepsy. J Neurovirol (2012) 0.78
Discovery of biologically active oncologic and immunologic small molecule therapies using zebrafish: overview and example of modulation of T cell activation. Curr Protoc Pharmacol (2013) 0.78
Manganese superoxide dismutase induction during measles virus infection. J Med Virol (2003) 0.78
Contrasting roles for Valpha14+ natural killer T cells in a viral model for multiple sclerosis. J Neurovirol (2008) 0.78
Cross-reactive myelin antibody induces renal pathology. Autoimmunity (2008) 0.77
Acthar gel treatment suppresses acute exacerbations in a murine model of relapsing-remitting multiple sclerosis. Autoimmunity (2014) 0.77
In vitro antigen-specific induction of IL-22 in human subjects that resolved HCV infection. Future Virol (2012) 0.76
A potential link between measles virus and autism: age-matched control groups are essential. Pediatr Neurol (2004) 0.75
Role of B:T cell ratio in suppression of clinical signs: a model for silent MS. Exp Mol Pathol (2008) 0.75
Immunization with structural and non-structural proteins of Theiler's murine encephalomyelitis virus alters demyelinating disease. J Neurovirol (2012) 0.75
Letting antibodies get to your head. Nat Med (2003) 0.75
Possible role of interleukin-17 in a prime/challenge model of multiple sclerosis. J Neurovirol (2012) 0.75
Axonal pathology and demyelination in viral models of multiple sclerosis. Discov Med (2014) 0.75
Are there altered antibody responses to measles, mumps, or rubella viruses in autism? J Neurovirol (2007) 0.75
Altered cell growth and morphology in a BHK-21 cell mutant that lacks a receptor for Theiler's murine encephalomyelitis virus. Virology (2002) 0.75