Published in Hum Antibodies on January 01, 1997
Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS). Br J Pharmacol (2011) 2.55
Integrin function in T-cell homing to lymphoid and nonlymphoid sites: getting there and staying there. Crit Rev Immunol (2009) 1.49
Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance. J Transl Med (2009) 1.35
Discordant effects of anti-VLA-4 treatment before and after onset of relapsing experimental autoimmune encephalomyelitis. J Clin Invest (2001) 1.32
Molecular pathways: VCAM-1 as a potential therapeutic target in metastasis. Clin Cancer Res (2012) 1.14
Anti-adhesion molecule therapy for inflammatory bowel disease. Therap Adv Gastroenterol (2010) 1.02
Neuropathogenesis of Theiler's murine encephalomyelitis virus infection, an animal model for multiple sclerosis. J Neuroimmune Pharmacol (2009) 1.01
Natalizumab in the treatment of multiple sclerosis. Ther Adv Neurol Disord (2009) 1.01
How natalizumab binds and antagonizes α4 integrins. J Biol Chem (2013) 0.95
Optimizing therapeutics in the management of patients with multiple sclerosis: a review of drug efficacy, dosing, and mechanisms of action. Biologics (2013) 0.92
Multiple sclerosis treatment and infectious issues: update 2013. Clin Exp Immunol (2014) 0.90
Classical and recent advances in the treatment of inflammatory bowel diseases. Braz J Med Biol Res (2014) 0.88
Natalizumab treatment of multiple sclerosis in Spain: results of an extensive observational study. J Neurol (2012) 0.88
A study of subtle blood brain barrier disruption in a placebo-controlled trial of natalizumab in relapsing remitting multiple sclerosis. J Neurol (2007) 0.88
Best practice in the use of natalizumab in multiple sclerosis. Ther Adv Neurol Disord (2013) 0.85
Autoimmunity and inflammation: murine models and translational studies. Mamm Genome (2011) 0.82
Inhibition of α4β1 integrin increases ovarian cancer response to carboplatin. Gynecol Oncol (2013) 0.81
Natalizumab: A new treatment for relapsing remitting multiple sclerosis. Ther Clin Risk Manag (2007) 0.81
Impact of antibody framework residue VH-71 on the stability of a humanised anti-MUC1 scFv and derived immunoenzyme. Br J Cancer (2004) 0.80
Immunological mechanism of action and clinical profile of disease-modifying treatments in multiple sclerosis. CNS Drugs (2014) 0.77
3D QSAR (COMFA) of a series of potent and highly selective VLA-4 antagonists. J Comput Aided Mol Des (2002) 0.76
Integrins as Therapeutic Targets: Successes and Cancers. Cancers (Basel) (2017) 0.75
Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin. Nature (1992) 7.20
Characterization of human prorenin expressed in mammalian cells from cloned cDNA. Proc Natl Acad Sci U S A (1986) 3.60
In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. Proc Natl Acad Sci U S A (1996) 3.53
Use of a rapid, single-round, multiplex PCR to detect malarial parasites and identify the species present. Ann Trop Med Parasitol (2003) 3.48
Cloning of a lymphocyte homing receptor reveals a lectin domain. Cell (1989) 3.33
Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues. Proc Natl Acad Sci U S A (1988) 2.95
In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system. Cell Death Differ (1998) 2.48
A cell culture model of the blood-brain barrier. J Cell Biol (1991) 2.35
Fas-induced activation of the cell death-related protease CPP32 Is inhibited by Bcl-2 and by ICE family protease inhibitors. J Biol Chem (1996) 2.26
Receptors involved in lymphocyte homing: relationship between a carbohydrate-binding receptor and the MEL-14 antigen. J Cell Biol (1987) 2.13
Can general practitioners influence the nation's health through a population approach to provision of lifestyle advice? Br J Gen Pract (2000) 1.98
Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-xL has activity independent of cytochrome c release. J Biol Chem (1997) 1.97
The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II. Nature (1989) 1.94
Involvement of sialic acid on endothelial cells in organ-specific lymphocyte recirculation. Science (1985) 1.85
Sequence and structure of VH domain from naturally occurring camel heavy chain immunoglobulins lacking light chains. Protein Eng (1994) 1.85
Regulatory mutants of polyoma virus defective in DNA replication and the synthesis of early proteins. Cell (1980) 1.85
Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide. Nature (1993) 1.85
The Alzheimer amyloid precursor protein. Identification of a stable intermediate in the biosynthetic/degradative pathway. J Biol Chem (1990) 1.83
Peroxide sensors for the fission yeast stress-activated mitogen-activated protein kinase pathway. Mol Biol Cell (2001) 1.80
Messenger RNA coding for only the alpha subunit of the rat brain Na channel is sufficient for expression of functional channels in Xenopus oocytes. Proc Natl Acad Sci U S A (1986) 1.79
Changes in pneumococcal serotypes and antibiotypes carried by vaccinated and unvaccinated day-care centre attendees in Portugal, a country with widespread use of the seven-valent pneumococcal conjugate vaccine. Clin Microbiol Infect (2009) 1.79
Reshaping a human antibody to inhibit the interleukin 6-dependent tumor cell growth. Cancer Res (1993) 1.77
Bax- and Bak-induced cell death in the fission yeast Schizosaccharomyces pombe. Mol Biol Cell (1997) 1.75
Phosphomannosyl-derivatized beads detect a receptor involved in lymphocyte homing. J Cell Biol (1987) 1.64
Genetic diversity and clonal patterns among antibiotic-susceptible and -resistant Streptococcus pneumoniae colonizing children: day care centers as autonomous epidemiological units. J Clin Microbiol (2000) 1.64
Viable deletion mutant in the medium and large T-antigen-coding sequences of the polyoma virus genome. J Virol (1980) 1.60
Dimerization properties of human BAD. Identification of a BH-3 domain and analysis of its binding to mutant BCL-2 and BCL-XL proteins. J Biol Chem (1997) 1.58
Apoptosis of sinusoidal endothelial cells occurs during liver preservation injury by a caspase-dependent mechanism. Transplantation (1999) 1.56
Homing receptors on human and rodent lymphocytes--evidence for a conserved carbohydrate-binding specificity. Blood (1987) 1.51
Peptide inhibitors of the ICE protease family arrest programmed cell death of motoneurons in vivo and in vitro. Neuron (1995) 1.46
Increasing population levels of physical activity through primary care: GPs' knowledge, attitudes and self-reported practice. Fam Pract (1999) 1.43
GlyCAM-1, a physiologic ligand for L-selectin, activates beta 2 integrins on naive peripheral lymphocytes. J Exp Med (1996) 1.39
T-lymphocyte subsets in acute illness. Crit Care Med (1995) 1.39
Carriage of respiratory tract pathogens and molecular epidemiology of Streptococcus pneumoniae colonization in healthy children attending day care centers in Lisbon, Portugal. Microb Drug Resist (1999) 1.38
Bcl-xL functions downstream of caspase-8 to inhibit Fas- and tumor necrosis factor receptor 1-induced apoptosis of MCF7 breast carcinoma cells. J Biol Chem (1998) 1.38
Persistence and expression of histone genes injected into Xenopus eggs in early development. Nature (1981) 1.34
Alpha 4 beta 1 integrin-dependent cell adhesion is regulated by a low affinity receptor pool that is conformationally responsive to ligand. J Biol Chem (1995) 1.33
Structural and functional complementation of an inactive Bcl-2 mutant by Bax truncation. J Biol Chem (1997) 1.32
Extensive cytotoxic lesions involving both the rhinal cortices and area TE impair recognition but spare spatial alternation in the rat. Brain Res Bull (1997) 1.31
A new procedure for examining Golgi impregnated neurons by light and electron microscopy. J Neurocytol (1977) 1.27
A common binding site mediates heterodimerization and homodimerization of Bcl-2 family members. J Biol Chem (1997) 1.24
Intravenously injected sialidase inactivates attachment sites for lymphocytes on high endothelial venules. J Immunol (1989) 1.21
Characterization and biological effects of recombinant human erythropoietin. Immunobiology (1986) 1.20
A monoclonal antibody to alpha 4 integrin suppresses and reverses active experimental allergic encephalomyelitis. J Neuroimmunol (1995) 1.20
The epidermolytic toxins are serine proteases. FEBS Lett (1990) 1.20
Activation of the CED3/ICE-related protease CPP32 in cerebellar granule neurons undergoing apoptosis but not necrosis. J Neurosci (1997) 1.19
Humanization of a mouse monoclonal antibody by CDR-grafting: the importance of framework residues on loop conformation. Protein Eng (1991) 1.18
Trends in drug resistance, serotypes, and molecular types of Streptococcus pneumoniae colonizing preschool-age children attending day care centers in Lisbon, Portugal: a summary of 4 years of annual surveillance. J Clin Microbiol (2005) 1.16
Natural history of drug-resistant clones of Streptococcus pneumoniae colonizing healthy children in Portugal. Microb Drug Resist (2005) 1.14
Genetic studies on the beta subunit of Escherichia coli RNA polymerase. VIII. Localisation of a region involved in promoter selectivity. Mol Gen Genet (1986) 1.14
Avermectin B1a irreversibly blocks postsynaptic potentials at the lobster neuromuscular junction by reducing muscle membrane resistance. Proc Natl Acad Sci U S A (1979) 1.13
Glucocorticoids inhibit glucose transport and glutamate uptake in hippocampal astrocytes: implications for glucocorticoid neurotoxicity. J Neurochem (1991) 1.12
Analytical and clinical sensitivity of West Nile virus RNA screening and supplemental assays available in 2003. Transfusion (2005) 1.12
Structure-function analysis of the integrin beta 7 subunit: identification of domains involved in adhesion to MAdCAM-1. J Immunol (1997) 1.10
Isolation and characterization of a monoclonal antibody against the saxitoxin-binding component from the electric organ of the eel Electrophorus electricus. Proc Natl Acad Sci U S A (1982) 1.10
Genetic studies on the beta subunit of Escherichia coli RNA polymerase. VII. RNA polymerase is a target for ppGpp. Mol Gen Genet (1986) 1.09
Regulation of conformation and ligand binding function of integrin alpha5beta1 by the beta1 cytoplasmic domain. J Biol Chem (1996) 1.08
In vivo activation of neutrophil function in hamsters by recombinant human granulocyte colony-stimulating factor. Infect Immun (1988) 1.07
Fidelity of transcription of Xenopus laevis globin genes injected into Xenopus laevis oocytes and unfertilized eggs. Mol Cell Biol (1984) 1.07
Direct suppression of natural killer activity in human peripheral blood leukocyte cultures by glucocorticoids and its modulation by interferon. Cancer Res (1983) 1.07
A role of chondroitin sulfate glycosaminoglycan binding site in alpha4beta1 integrin-mediated melanoma cell adhesion. J Biol Chem (1998) 1.06
Deletion mutants of polyoma virus defining a nonessential region between the origin of replication and the initiation codon for early proteins. J Virol (1979) 1.06
Acne keloidalis in women. Cutis (1989) 1.05
Guidelines for low back pain: changes in GP management. Fam Pract (1999) 1.05
Optimization of primers for cloning libraries of mouse immunoglobulin genes using the polymerase chain reaction. Eur J Immunol (1993) 1.05
Rapid PCR-cloning of full-length mouse immunoglobulin variable regions. Biotechnology (N Y) (1991) 1.04
Differential expression of the Xenopus laevis tadpole and adult beta-globin genes when injected into fertilized Xenopus laevis eggs. Mol Cell Biol (1984) 1.03
Replication and expression of Xenopus laevis globin genes injected into fertilized Xenopus eggs. Proc Natl Acad Sci U S A (1983) 1.01
Peptidomimetic fluoromethylketone rescues mice from lethal endotoxic shock. Mol Med (1999) 1.00
Activation of membrane-associated procaspase-3 is regulated by Bcl-2. J Cell Biol (1999) 0.98
Endothelial selectins and alpha4 integrins regulate independent pathways of T lymphocyte recruitment in the pulmonary immune response. J Immunol (1998) 0.96
Structural studies on the PH domains of Db1, Sos1, IRS-1, and beta ARK1 and their differential binding to G beta gamma subunits. Biochemistry (1995) 0.96
The effect of synaptic activation on the extracellular potassium concentration in the hippocampal dentate area, in vitro. Brain Res (1976) 0.96
Irreversible caspase inhibitors: tools for studying apoptosis. Methods (1999) 0.95
Comparison of Faxén's correction for a microsphere translating or rotating near a surface. Phys Rev E Stat Nonlin Soft Matter Phys (2009) 0.95
Studies on the mechanism of action of avermectin B1a: stimulation of release of gamma-aminobutyric acid from brain synaptosomes. J Neurochem (1980) 0.94
Transcription of sea urchin histone genes in HeLa cells. Nucleic Acids Res (1983) 0.93
Evidence for a dose-dependent inflammatory response to quartz in the rat lung and its significance in early changes in collagen metabolism. Environ Health Perspect (1983) 0.93
Role of the adrenal cortex in gastric mucosal protection by prostaglandins, sulfhydryls, and cimetidine in the rat. Gastroenterology (1983) 0.93
Immunological evidence that inactive renin is prorenin. Biochem Biophys Res Commun (1985) 0.91
Blood donor screening with cobas s 201/cobas TaqScreen MPX under routine conditions at German Red Cross institutes. Vox Sang (2009) 0.90
Prolonged reversal of chronic experimental allergic encephalomyelitis using a small molecule inhibitor of alpha4 integrin. J Neuroimmunol (2002) 0.90
Immunochemical properties and cytochemical localization of the voltage-sensitive sodium channel from the electroplax of the eel (Electrophorus electricus). J Neurosci (1983) 0.90
Endoscopists' estimation of size should not determine surveillance of colonic polyps. Colorectal Dis (2009) 0.89
A chimaeric plant virus vaccine protects mice against a bacterial infection. Microbiology (1999) 0.89
Human renin is correctly processed and targeted to the regulated secretory pathway in mouse pituitary AtT-20 cells. J Biol Chem (1987) 0.87
Enhanced muscle insulin receptor autophosphorylation with short-term aerobic exercise training. Am J Physiol Endocrinol Metab (2001) 0.87
In vivo treatment with anti-alpha4 integrin suppresses clinical and pathological evidence of Borna disease virus infection. J Neuroimmunol (1998) 0.87
Characterization of transduction by bacteriophage T1: time of production and density of transducing particles. J Virol (1975) 0.87
Continuous subcutaneous insulin infusion in Type 1 diabetes: patient experiences of 'living with a machine'. Diabet Med (2010) 0.86
Analysis and quantitation of the beta-amyloid precursor protein in the cerebrospinal fluid of Alzheimer's disease patients with a monoclonal antibody-based immunoassay. J Neurochem (1991) 0.86
Inactivated recombinant plant virus protects dogs from a lethal challenge with canine parvovirus. Vaccine (2001) 0.86
Differential regulation of beta1 integrins by chemoattractants regulates neutrophil migration through fibrin. J Cell Biol (1999) 0.86
Characteristics of internet child pornography offenders: a comparison with child molesters. Sex Abuse (2007) 0.86