Published in FEBS J on November 06, 2009
Revisiting the central metabolism of the bloodstream forms of Trypanosoma brucei: production of acetate in the mitochondrion is essential for parasite viability. PLoS Negl Trop Dis (2013) 0.95
Identification and characterization of a stage specific membrane protein involved in flagellar attachment in Trypanosoma brucei. PLoS One (2013) 0.87
ATP synthesis-coupled and -uncoupled acetate production from acetyl-CoA by mitochondrial acetate:succinate CoA-transferase and acetyl-CoA thioesterase in Trypanosoma. J Biol Chem (2012) 0.86
Dynamic modelling under uncertainty: the case of Trypanosoma brucei energy metabolism. PLoS Comput Biol (2012) 0.86
Probing the metabolic network in bloodstream-form Trypanosoma brucei using untargeted metabolomics with stable isotope labelled glucose. PLoS Pathog (2015) 0.83
Identification and characterization of an unusual class I myosin involved in vesicle traffic in Trypanosoma brucei. PLoS One (2010) 0.81
Specific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African Trypanosomiasis. PLoS Pathog (2015) 0.81
Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryot Cell (2012) 0.80
Putative mitochondrial α-ketoglutarate-dependent dioxygenase Fmp12 controls utilization of proline as an energy source in Saccharomyces cerevisiae. Microb Cell (2016) 0.75
Trypanosoma brucei metabolite indolepyruvate decreases HIF-1α and glycolysis in macrophages as a mechanism of innate immune evasion. Proc Natl Acad Sci U S A (2016) 0.75
The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. Science (2005) 7.61
Comparative genomic analysis of three Leishmania species that cause diverse human disease. Nat Genet (2007) 4.58
Apolipoprotein L-I is the trypanosome lytic factor of human serum. Nature (2003) 4.33
Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes. Science (2005) 3.06
Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration. Mult Scler (2010) 1.84
Metabolic functions of glycosomes in trypanosomatids. Biochim Biophys Acta (2006) 1.80
A differential role for actin during the life cycle of Trypanosoma brucei. EMBO J (2004) 1.79
The trypanolytic factor of human serum. Nat Rev Microbiol (2006) 1.64
Sequencing of the smallest Apicomplexan genome from the human pathogen Babesia microti. Nucleic Acids Res (2012) 1.49
Proline metabolism in procyclic Trypanosoma brucei is down-regulated in the presence of glucose. J Biol Chem (2005) 1.44
The genome of the heartworm, Dirofilaria immitis, reveals drug and vaccine targets. FASEB J (2012) 1.40
A chromosomal SIR2 homologue with both histone NAD-dependent ADP-ribosyltransferase and deacetylase activities is involved in DNA repair in Trypanosoma brucei. EMBO J (2003) 1.37
Energy generation in insect stages of Trypanosoma brucei: metabolism in flux. Trends Parasitol (2005) 1.34
The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism. Nucleic Acids Res (2003) 1.33
Evolution of energy metabolism and its compartmentation in Kinetoplastida. Kinetoplastid Biol Dis (2003) 1.33
Mechanism of Trypanosoma brucei gambiense resistance to human serum. Nature (2013) 1.28
Glucose-induced remodeling of intermediary and energy metabolism in procyclic Trypanosoma brucei. J Biol Chem (2008) 1.26
The architecture of variant surface glycoprotein gene expression sites in Trypanosoma brucei. Mol Biochem Parasitol (2002) 1.20
Acetyl:succinate CoA-transferase in procyclic Trypanosoma brucei. Gene identification and role in carbohydrate metabolism. J Biol Chem (2004) 1.16
ATP generation in the Trypanosoma brucei procyclic form: cytosolic substrate level is essential, but not oxidative phosphorylation. J Biol Chem (2003) 1.15
A mitochondrial NADH-dependent fumarate reductase involved in the production of succinate excreted by procyclic Trypanosoma brucei. J Biol Chem (2005) 1.09
When, how and why glycolysis became compartmentalised in the Kinetoplastea. A new look at an ancient organelle. Int J Parasitol (2011) 1.08
Mitochondrial energetics is impaired in vivo in aged skeletal muscle. Aging Cell (2013) 1.06
Acetate produced in the mitochondrion is the essential precursor for lipid biosynthesis in procyclic trypanosomes. Proc Natl Acad Sci U S A (2009) 1.04
Organization and evolution of two SIDER retroposon subfamilies and their impact on the Leishmania genome. BMC Genomics (2009) 1.04
Monitoring demyelination and remyelination by magnetization transfer imaging in the mouse brain at 9.4 T. MAGMA (2008) 1.02
Fumarate is an essential intermediary metabolite produced by the procyclic Trypanosoma brucei. J Biol Chem (2006) 0.99
A soluble pyrophosphatase, a key enzyme for polyphosphate metabolism in Leishmania. J Biol Chem (2005) 0.96
Succinate secreted by Trypanosoma brucei is produced by a novel and unique glycosomal enzyme, NADH-dependent fumarate reductase. J Biol Chem (2002) 0.96
Nucleotide sequence of the gyrA gene of Arcobacter species and characterization of human ciprofloxacin-resistant clinical isolates. FEMS Immunol Med Microbiol (2007) 0.96
Increasing the mass accuracy of high-resolution LC-MS data using background ions: a case study on the LTQ-Orbitrap. Proteomics (2008) 0.95
Two related subpellicular cytoskeleton-associated proteins in Trypanosoma brucei stabilize microtubules. Mol Biol Cell (2002) 0.95
A protein kinase specifically associated with proliferative forms of Trypanosoma brucei is functionally related to a yeast kinase involved in the co-ordination of cell shape and division. Mol Microbiol (2002) 0.93
Interaction of substituted hexose analogues with the Trypanosoma brucei hexose transporter. Biochem Pharmacol (2004) 0.91
Characterization of two protein disulfide isomerases from the endocytic pathway of bloodstream forms of Trypanosoma brucei. J Biol Chem (2005) 0.91
The threonine degradation pathway of the Trypanosoma brucei procyclic form: the main carbon source for lipid biosynthesis is under metabolic control. Mol Microbiol (2013) 0.90
Ablation of succinate production from glucose metabolism in the procyclic trypanosomes induces metabolic switches to the glycerol 3-phosphate/dihydroxyacetone phosphate shuttle and to proline metabolism. J Biol Chem (2010) 0.88
Cell-penetrating peptide TP10 shows broad-spectrum activity against both Plasmodium falciparum and Trypanosoma brucei brucei. Antimicrob Agents Chemother (2008) 0.88
Identification and characterization of a stage specific membrane protein involved in flagellar attachment in Trypanosoma brucei. PLoS One (2013) 0.87
ATP synthesis-coupled and -uncoupled acetate production from acetyl-CoA by mitochondrial acetate:succinate CoA-transferase and acetyl-CoA thioesterase in Trypanosoma. J Biol Chem (2012) 0.86
Influence of cultivation conditions on the production of a thermostable extracellular lipase from Amycolatopsis mediterranei DSM 43304. J Ind Microbiol Biotechnol (2009) 0.86
Transketolase in Trypanosoma brucei. Mol Biochem Parasitol (2011) 0.86
Occupational noise exposure of nightclub bar employees in Ireland. Noise Health (2012) 0.82
Functional characterization of TbMCP5, a conserved and essential ADP/ATP carrier present in the mitochondrion of the human pathogen Trypanosoma brucei. J Biol Chem (2012) 0.82
Purification and properties of Amycolatopsis mediterranei DSM 43304 lipase and its potential in flavour ester synthesis. Bioresour Technol (2010) 0.82
Inhibition of late-stage autophagy synergistically enhances pyrrolo-1,5-benzoxazepine-6-induced apoptotic cell death in human colon cancer cells. Int J Oncol (2013) 0.81
A kinetoplastid BRCA2 interacts with DNA replication protein CDC45. Int J Parasitol (2008) 0.81
Identification and characterization of an unusual class I myosin involved in vesicle traffic in Trypanosoma brucei. PLoS One (2010) 0.81
MRI of inducible P-selectin expression in human activated platelets involved in the early stages of atherosclerosis. NMR Biomed (2010) 0.81
Characterization of cinnamyl alcohol dehydrogenase of Helicobacter pylori. An aldehyde dismutating enzyme. FEBS J (2005) 0.80
The characterization and evolutionary relationships of a trypanosomal thiolase. Int J Parasitol (2011) 0.80
Cytosolic NADPH homeostasis in glucose-starved procyclic Trypanosoma brucei relies on malic enzyme and the pentose phosphate pathway fed by gluconeogenic flux. J Biol Chem (2013) 0.80
Flux Analysis of the Trypanosoma brucei Glycolysis Based on a Multiobjective-Criteria Bioinformatic Approach. Adv Bioinformatics (2012) 0.80
[Comparative genomics of trypanosomatid parasitic protozoa]. Med Sci (Paris) (2005) 0.79
The vascular targeting agent Combretastatin-A4 directly induces autophagy in adenocarcinoma-derived colon cancer cells. Biochem Pharmacol (2012) 0.78
Vitamin A deficiency in rats induces anatomic and metabolic changes comparable with those of neurodegenerative disorders. J Nutr (2009) 0.78
Aldo-keto reductase from Helicobacter pylori--role in adaptation to growth at acid pH. FEBS J (2008) 0.77
Adapted focal experimental autoimmune encephalomyelitis to allow MRI exploration of multiple sclerosis features. Exp Neurol (2011) 0.77
Simultaneous modelling of the thermal degradation kinetics of pectin methylesterase in lettuce (Lactuca sativa L.) and carrot (Daucus carota L.) extracts: analysis of seasonal variation and tissue type. Biosci Biotechnol Biochem (2007) 0.77
Synthesis of novel benzamidine- and guanidine-derived polyazamacrocycles: Selective anti-protozoal activity for human African trypanosomiasis. Bioorg Med Chem Lett (2008) 0.77
Isotopic profiling of ¹³C-labeled biological samples by two-dimensional heteronuclear J-resolved nuclear magnetic resonance spectroscopy. Anal Biochem (2012) 0.76
A short chain NAD(H)-dependent alcohol dehydrogenase (HpSCADH) from Helicobacter pylori: a role in growth under neutral and acidic conditions. Int J Biochem Cell Biol (2013) 0.76
Effect of heat shock on browning-related enzymes in minimally processed iceberg lettuce and crude extracts. Biosci Biotechnol Biochem (2005) 0.75
Substrate profiling and aldehyde dismutase activity of the Kvβ2 subunit of the mammalian Kv1 potassium channel. Int J Biochem Cell Biol (2010) 0.75
Synthesis and anti-protozoal activity of C2-substituted polyazamacrocycles. Bioorg Med Chem Lett (2008) 0.75