Published in Am J Hum Genet on November 05, 2009
A versatile gene-based test for genome-wide association studies. Am J Hum Genet (2010) 8.44
Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits. Nat Genet (2012) 5.55
Web-based, participant-driven studies yield novel genetic associations for common traits. PLoS Genet (2010) 5.02
A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications. Biol Psychiatry (2011) 2.87
Genome-wide association study identifies a locus at 7p15.2 associated with endometriosis. Nat Genet (2010) 2.04
Detection and replication of epistasis influencing transcription in humans. Nature (2014) 1.95
Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect. Eur J Hum Genet (2013) 1.72
Efficient replication of over 180 genetic associations with self-reported medical data. PLoS One (2011) 1.65
The Brisbane Systems Genetics Study: genetical genomics meets complex trait genetics. PLoS One (2012) 1.49
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus. Nat Genet (2013) 1.49
Genome-wide association study of height and body mass index in Australian twin families. Twin Res Hum Genet (2010) 1.44
Genome-wide association meta-analysis identifies new endometriosis risk loci. Nat Genet (2012) 1.42
The perception of quinine taste intensity is associated with common genetic variants in a bitter receptor cluster on chromosome 12. Hum Mol Genet (2010) 1.36
Genome-wide comparison of African-ancestry populations from CARe and other cohorts reveals signals of natural selection. Am J Hum Genet (2011) 1.35
Congruence of additive and non-additive effects on gene expression estimated from pedigree and SNP data. PLoS Genet (2013) 1.35
A variant in LIN28B is associated with 2D:4D finger-length ratio, a putative retrospective biomarker of prenatal testosterone exposure. Am J Hum Genet (2010) 1.32
A 3p26-3p25 genetic linkage finding for DSM-IV major depression in heavy smoking families. Am J Psychiatry (2011) 1.32
Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia. Eur J Hum Genet (2010) 1.27
Contribution of genetic variation to transgenerational inheritance of DNA methylation. Genome Biol (2014) 1.20
Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins. Transl Psychiatry (2014) 1.14
A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features. Nat Commun (2016) 1.13
Genetic and environmental exposures constrain epigenetic drift over the human life course. Genome Res (2014) 1.13
Genetic predisposition to schizophrenia associated with increased use of cannabis. Mol Psychiatry (2014) 1.13
A genome-wide association study of Cloninger's temperament scales: implications for the evolutionary genetics of personality. Biol Psychol (2010) 1.12
Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM. Mol Psychiatry (2011) 1.08
Genome-wide linkage and association analyses implicate FASN in predisposition to Uterine Leiomyomata. Am J Hum Genet (2012) 1.08
Whole genome association scan for genetic polymorphisms influencing information processing speed. Biol Psychol (2010) 1.07
Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits. BMC Med Genet (2011) 1.06
Gene network effects on brain microstructure and intellectual performance identified in 472 twins. J Neurosci (2012) 1.04
Inference of the genetic architecture underlying BMI and height with the use of 20,240 sibling pairs. Am J Hum Genet (2013) 1.04
Discovery and replication of dopamine-related gene effects on caudate volume in young and elderly populations (N=1198) using genome-wide search. Mol Psychiatry (2011) 1.03
Predicting white matter integrity from multiple common genetic variants. Neuropsychopharmacology (2012) 1.01
GWAS findings for human iris patterns: associations with variants in genes that influence normal neuronal pattern development. Am J Hum Genet (2011) 1.01
The genetic aetiology of cannabis use initiation: a meta-analysis of genome-wide association studies and a SNP-based heritability estimation. Addict Biol (2012) 1.01
Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight. JAMA (2016) 1.00
A genome-wide association study of sleep habits and insomnia. Am J Med Genet B Neuropsychiatr Genet (2013) 0.98
Loci affecting gamma-glutamyl transferase in adults and adolescents show age × SNP interaction and cardiometabolic disease associations. Hum Mol Genet (2011) 0.98
A genome-wide association study for reading and language abilities in two population cohorts. Genes Brain Behav (2013) 0.95
Autosomal-dominant woolly hair resulting from disruption of keratin 74 (KRT74), a potential determinant of human hair texture. Am J Hum Genet (2010) 0.95
A genome-wide association study of caffeine-related sleep disturbance: confirmation of a role for a common variant in the adenosine receptor. Sleep (2012) 0.94
Mining the human phenome using allelic scores that index biological intermediates. PLoS Genet (2013) 0.94
Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder. Transl Psychiatry (2012) 0.94
Unraveling the genetic etiology of adult antisocial behavior: a genome-wide association study. PLoS One (2012) 0.94
Epidermal transglutaminase (TGase 3) is required for proper hair development, but not the formation of the epidermal barrier. PLoS One (2012) 0.94
Genetic risk score analysis indicates migraine with and without comorbid depression are genetically different disorders. Hum Genet (2013) 0.94
Meta-analysis of genome-wide association studies identifies common variants in CTNNA2 associated with excitement-seeking. Transl Psychiatry (2011) 0.93
Genome-wide association study identifies loci affecting blood copper, selenium and zinc. Hum Mol Genet (2013) 0.93
GWAS of butyrylcholinesterase activity identifies four novel loci, independent effects within BCHE and secondary associations with metabolic risk factors. Hum Mol Genet (2011) 0.91
Prediction of lung cancer risk in a Chinese population using a multifactorial genetic model. BMC Med Genet (2012) 0.89
The role of conduct disorder in the relationship between alcohol, nicotine and cannabis use disorders. Psychol Med (2015) 0.88
Genome-wide association study of a quantitative disordered gambling trait. Addict Biol (2012) 0.88
Trichohyalin-like proteins have evolutionarily conserved roles in the morphogenesis of skin appendages. J Invest Dermatol (2014) 0.87
Transcriptome profile at different physiological stages reveals potential mode for curly fleece in Chinese tan sheep. PLoS One (2013) 0.87
No association of candidate genes with cannabis use in a large sample of Australian twin families. Addict Biol (2011) 0.87
Genome-wide association study identifies two loci strongly affecting transferrin glycosylation. Hum Mol Genet (2011) 0.87
The adaptive variant EDARV370A is associated with straight hair in East Asians. Hum Genet (2013) 0.86
Identification of tag haplotypes for 5HTTLPR for different genome-wide SNP platforms. Mol Psychiatry (2011) 0.86
Educational attainment: a genome wide association study in 9538 Australians. PLoS One (2011) 0.86
Identity-by-descent mapping to detect rare variants conferring susceptibility to multiple sclerosis. PLoS One (2013) 0.85
The ATXN1 and TRIM31 genes are related to intelligence in an ADHD background: evidence from a large collaborative study totaling 4,963 subjects. Am J Med Genet B Neuropsychiatr Genet (2010) 0.84
Genome-wide association study of blood lead shows multiple associations near ALAD. Hum Mol Genet (2015) 0.84
Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations. Am J Hum Genet (2015) 0.83
An integrated approach to reduce the impact of minor allele frequency and linkage disequilibrium on variable importance measures for genome-wide data. Bioinformatics (2012) 0.83
A new regulatory variant in the interleukin-6 receptor gene associates with asthma risk. Genes Immun (2013) 0.83
A genome-wide study on the perception of the odorants androstenone and galaxolide. Chem Senses (2012) 0.83
A genome-wide association study of self-rated health. Twin Res Hum Genet (2010) 0.82
Evidence of differential allelic effects between adolescents and adults for plasma high-density lipoprotein. PLoS One (2012) 0.81
Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions. Eur J Hum Genet (2012) 0.79
Evaluation of DNA variants associated with androgenetic alopecia and their potential to predict male pattern baldness. PLoS One (2015) 0.79
Genetic basis of a cognitive complexity metric. PLoS One (2015) 0.79
Identification of Common Genetic Variants Influencing Spontaneous Dizygotic Twinning and Female Fertility. Am J Hum Genet (2016) 0.79
Forensically relevant SNaPshot(®) assays for human DNA SNP analysis: a review. Int J Legal Med (2016) 0.79
Gradient Boosting as a SNP Filter: an Evaluation Using Simulated and Hair Morphology Data. J Data Mining Genomics Proteomics (2013) 0.78
The mouse wellhaarig (we) mutations result from defects in epidermal-type transglutaminase 3 (Tgm3). Mol Genet Metab (2015) 0.77
Shared genetic control of expression and methylation in peripheral blood. BMC Genomics (2016) 0.77
EDARV370A associated facial characteristics in Uyghur population revealing further pleiotropic effects. Hum Genet (2015) 0.76
Genome-wide polygenic scores for age at onset of alcohol dependence and association with alcohol-related measures. Transl Psychiatry (2016) 0.76
Association between in vivo alcohol metabolism and genetic variation in pathways that metabolize the carbon skeleton of ethanol and NADH reoxidation in the alcohol challenge twin study. Alcohol Clin Exp Res (2012) 0.76
Obesity gene NEGR1 associated with white matter integrity in healthy young adults. Neuroimage (2014) 0.76
First all-in-one diagnostic tool for DNA intelligence: genome-wide inference of biogeographic ancestry, appearance, relatedness, and sex with the Identitas v1 Forensic Chip. Int J Legal Med (2012) 0.75
GW-SEM: A Statistical Package to Conduct Genome-Wide Structural Equation Modeling. Behav Genet (2017) 0.75
A continuum of genetic liability for minor and major depression. Transl Psychiatry (2017) 0.75
Genome-wide association study of working memory brain activation. Int J Psychophysiol (2016) 0.75
Identification and comparative analysis of the epidermal differentiation complex in snakes. Sci Rep (2017) 0.75
Common variants in the CYP2C19 gene are associated with susceptibility to endometriosis. Fertil Steril (2014) 0.75
A twin study of breastfeeding with a preliminary genome-wide association scan. Twin Res Hum Genet (2014) 0.75
The Impact of Evolutionary Driving Forces on Human Complex Diseases: A Population Genetics Approach. Scientifica (Cairo) (2016) 0.75
Signatures of natural selection on genetic variants affecting complex human traits. Appl Transl Genom (2013) 0.75
Genetic prediction of male pattern baldness. PLoS Genet (2017) 0.75
Examining non-syndromic autosomal recessive intellectual disability (NS-ARID) genes for an enriched association with intelligence differences. Intelligence (2016) 0.75
Genome-wide scans reveal variants at EDAR predominantly affecting hair straightness in Han Chinese and Uyghur populations. Hum Genet (2016) 0.75
The International HapMap Project. Nature (2003) 73.65
SIFT: Predicting amino acid changes that affect protein function. Nucleic Acids Res (2003) 52.26
Human non-synonymous SNPs: server and survey. Nucleic Acids Res (2002) 50.45
A map of recent positive selection in the human genome. PLoS Biol (2006) 29.19
Worldwide human relationships inferred from genome-wide patterns of variation. Science (2008) 22.44
Positive natural selection in the human lineage. Science (2006) 12.55
PMUT: a web-based tool for the annotation of pathological mutations on proteins. Bioinformatics (2005) 9.88
Signals of recent positive selection in a worldwide sample of human populations. Genome Res (2009) 8.38
The genomic distribution of population substructure in four populations using 8,525 autosomal SNPs. Hum Genomics (2004) 3.53
A single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye color. Am J Hum Genet (2008) 3.00
A major quantitative-trait locus for mole density is linked to the familial melanoma gene CDKN2A: a maximum-likelihood combined linkage and association analysis in twins and their sibs. Am J Hum Genet (1999) 2.15
A three-single-nucleotide polymorphism haplotype in intron 1 of OCA2 explains most human eye-color variation. Am J Hum Genet (2006) 2.14
A scan for genetic determinants of human hair morphology: EDAR is associated with Asian hair thickness. Hum Mol Genet (2007) 1.96
Oxidation of methionine residues of proteins: biological consequences. Antioxid Redox Signal (2003) 1.88
Mutation in WNT10A is associated with an autosomal recessive ectodermal dysplasia: the odonto-onycho-dermal dysplasia. Am J Hum Genet (2007) 1.82
A genome-wide scan for naevus count: linkage to CDKN2A and to other chromosome regions. Eur J Hum Genet (2006) 1.70
Long-term stability and heritability of telephone interview measures of alcohol consumption and dependence. Twin Res Hum Genet (2008) 1.28
Worldwide diversity of hair curliness: a new method of assessment. Int J Dermatol (2007) 1.05
Analysis of the sheep trichohyalin gene: potential structural and calcium-binding roles of trichohyalin in the hair follicle. J Cell Biol (1993) 1.02
Linkage mapping of wool keratin and keratin-associated protein genes in sheep. Mamm Genome (1997) 1.01
Tandem-repeat internal mapping (TRIM) of the involucrin gene: repeat number and repeat-pattern polymorphism within a coding region in human populations. Am J Hum Genet (1993) 1.00
Origin of the polymorphism of the involucrin gene in Asians. Am J Hum Genet (1995) 0.90
Estimating the heritability of hair curliness in twins of European ancestry. Twin Res Hum Genet (2009) 0.89
Human hair keratin network and curvature. Int J Dermatol (2007) 0.87
[Evolutionary aspects of hair polymorphism]. Izv Akad Nauk Ser Biol (2006) 0.86
FGFR2 is associated with hair thickness in Asian populations. J Hum Genet (2009) 0.86
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
A core gut microbiome in obese and lean twins. Nature (2008) 52.30
Common SNPs explain a large proportion of the heritability for human height. Nat Genet (2010) 35.02
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Association between microdeletion and microduplication at 16p11.2 and autism. N Engl J Med (2008) 19.71
Human gut microbiome viewed across age and geography. Nature (2012) 19.31
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet (2010) 17.38
Practical aspects of imputation-driven meta-analysis of genome-wide association studies. Hum Mol Genet (2008) 13.26
Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Hum Mol Genet (2006) 13.16
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet (2008) 12.32
Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science (2013) 8.81
A versatile gene-based test for genome-wide association studies. Am J Hum Genet (2010) 8.44
Escalation of drug use in early-onset cannabis users vs co-twin controls. JAMA (2003) 8.29
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet (2011) 7.98
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Novel genes identified in a high-density genome wide association study for nicotine dependence. Hum Mol Genet (2006) 7.90
Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings. PLoS Genet (2006) 7.13
Recent human effective population size estimated from linkage disequilibrium. Genome Res (2007) 6.79
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet (2010) 6.49
Heritability of adult body height: a comparative study of twin cohorts in eight countries. Twin Res (2003) 6.43
A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry (2012) 6.34
DNA methylation profiles in monozygotic and dizygotic twins. Nat Genet (2009) 5.99
Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder. Am J Hum Genet (2009) 5.98
Viruses in the faecal microbiota of monozygotic twins and their mothers. Nature (2010) 5.92
Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits. Nat Genet (2012) 5.55
The long-term stability of the human gut microbiota. Science (2013) 5.15
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet (2009) 4.97
A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population. Nat Genet (2010) 4.96
Genomic inflation factors under polygenic inheritance. Eur J Hum Genet (2011) 4.89
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation. PLoS Genet (2008) 4.57
The role of childhood risk factors in initiation of alcohol use and progression to alcohol dependence. Addiction (2007) 4.55
The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins. Sci Transl Med (2011) 4.24
Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet (2010) 3.91
Genome-wide association study identifies three loci associated with melanoma risk. Nat Genet (2009) 3.89
Identification of seven loci affecting mean telomere length and their association with disease. Nat Genet (2013) 3.87
Bias, precision and heritability of self-reported and clinically measured height in Australian twins. Hum Genet (2006) 3.84
Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet (2013) 3.81
Common sequence variants on 20q11.22 confer melanoma susceptibility. Nat Genet (2008) 3.79