Preclinical study of prolonged administration of trastuzumab as combination therapy after disease progression during trastuzumab monotherapy.

PubWeight™: 1.52‹?› | Rank: Top 4%

🔗 View Article (PMID 19904537)

Published in Cancer Chemother Pharmacol on November 11, 2009

Authors

Kaori Fujimoto-Ouchi1, Fumiko Sekiguchi, Kaname Yamamoto, Masatoshi Shirane, Yoriko Yamashita, Kazushige Mori

Author Affiliations

1: Product Research Department, Chugai Pharmaceuticals Co., Ltd, 200 Kajiwara, Kamakura, Kanagawa, 247-8530, Japan. ohuchikor@chugai-pharm.co.jp

Articles by these authors

Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis. Proc Natl Acad Sci U S A (2011) 2.01

Antitumor activity of trastuzumab in combination with chemotherapy in human gastric cancer xenograft models. Cancer Chemother Pharmacol (2006) 1.51

Distinct roles for protease-activated receptors 1 and 2 in vasomotor modulation in rat superior mesenteric artery. Cardiovasc Res (2004) 1.45

A protective role of hydrogen sulfide against oxidative stress in rat gastric mucosal epithelium. Toxicology (2007) 1.38

Hydrogen sulfide as a novel nociceptive messenger. Pain (2007) 1.32

Prediction of sensitivity of rectal cancer cells in response to preoperative radiotherapy by DNA microarray analysis of gene expression profiles. Cancer Res (2006) 1.30

Hyperalgesia induced by spinal and peripheral hydrogen sulfide: evidence for involvement of Cav3.2 T-type calcium channels. Pain (2009) 1.17

ALK+, CD30-, CD20- large B-cell lymphoma containing anaplastic lymphoma kinase (ALK) fused to clathrin heavy chain gene (CLTC). Mod Pathol (2003) 1.15

Efficient production of infectious viruses requires enzymatic activity of Epstein-Barr virus protein kinase. Virology (2009) 1.13

The human cytomegalovirus gene products essential for late viral gene expression assemble into prereplication complexes before viral DNA replication. J Virol (2011) 1.12

Bevacizumab improves the delivery and efficacy of paclitaxel. Anticancer Drugs (2010) 1.12

Homozygous deletion of CDKN2A/2B is a hallmark of iron-induced high-grade rat mesothelioma. Lab Invest (2010) 1.12

Antitumor activity of erlotinib in combination with capecitabine in human tumor xenograft models. Cancer Chemother Pharmacol (2005) 1.09

Hydrogen sulfide inhibits activity of three isoforms of recombinant nitric oxide synthase. Toxicology (2007) 1.09

Analysis of the function of a hyperthermophilic endoglucanase from Pyrococcus horikoshii that hydrolyzes crystalline cellulose. Extremophiles (2004) 1.09

Iron overload signature in chrysotile-induced malignant mesothelioma. J Pathol (2012) 1.08

Diffuse large B-cell lymphoma initially manifesting in the bone marrow. Am J Clin Pathol (2007) 1.03

Immunohistochemical Ki67 labeling index has similar proliferation predictive power to various gene signatures in breast cancer. Cancer Sci (2012) 1.01

Potent and metabolically stable agonists for protease-activated receptor-2: evaluation of activity in multiple assay systems in vitro and in vivo. J Pharmacol Exp Ther (2004) 1.01

Fenton reaction induced cancer in wild type rats recapitulates genomic alterations observed in human cancer. PLoS One (2012) 1.00

Expression of chromobox homolog 7 (CBX7) is associated with poor prognosis in ovarian clear cell adenocarcinoma via TRAIL-induced apoptotic pathway regulation. Int J Cancer (2014) 0.99

Effective tumor targeted gene transfer using PEGylated adenovirus vector via systemic administration. J Control Release (2007) 0.99

PEGylated adenovirus vectors containing RGD peptides on the tip of PEG show high transduction efficiency and antibody evasion ability. J Gene Med (2005) 0.97

Suppression of pancreatitis-related allodynia/hyperalgesia by proteinase-activated receptor-2 in mice. Br J Pharmacol (2006) 0.96

Upregulation of Ca(v)3.2 T-type calcium channels targeted by endogenous hydrogen sulfide contributes to maintenance of neuropathic pain. Pain (2010) 0.96

Antitumor activity of combinations of anti-HER-2 antibody trastuzumab and oral fluoropyrimidines capecitabine/5'-dFUrd in human breast cancer models. Cancer Chemother Pharmacol (2001) 0.95

c-Maf expression in angioimmunoblastic T-cell lymphoma. Am J Surg Pathol (2007) 0.93

Schedule-dependent antitumor activity of the combination with erlotinib and docetaxel in human non-small cell lung cancer cells with EGFR mutation, KRAS mutation or both wild-type EGFR and KRAS. Oncol Rep (2010) 0.93

Hydrogen sulfide-induced mechanical hyperalgesia and allodynia require activation of both Cav3.2 and TRPA1 channels in mice. Br J Pharmacol (2012) 0.92

Spatiotemporally different DNA repair systems participate in Epstein-Barr virus genome maturation. J Virol (2011) 0.91

Erlotinib inhibits osteolytic bone invasion of human non-small-cell lung cancer cell line NCI-H292. Clin Exp Metastasis (2011) 0.90

Clinicopathological features and prognostic factors of Japanese patients with "peripheral T-cell lymphoma, unspecified" diagnosed according to the WHO classification. Leuk Res (2004) 0.90

Signal transduction for proteinase-activated receptor-2-triggered prostaglandin E2 formation in human lung epithelial cells. J Pharmacol Exp Ther (2005) 0.90

Apocynin, an NADPH oxidase inhibitor, suppresses rat prostate carcinogenesis. Cancer Sci (2013) 0.89

The proteinase inhibitor camostat mesilate suppresses pancreatic pain in rodents. Life Sci (2007) 0.88

Modulation of capsaicin-evoked visceral pain and referred hyperalgesia by protease-activated receptors 1 and 2. J Pharmacol Sci (2004) 0.88

A protective role of protease-activated receptor 1 in rat gastric mucosa. Gastroenterology (2004) 0.88

β4GalT6 is involved in the synthesis of lactosylceramide with less intensity than β4GalT5. Glycobiology (2013) 0.87

Intratumoral localization of aromatase and interaction between stromal and parenchymal cells in the non-small cell lung carcinoma microenvironment. Cancer Res (2010) 0.87

Hydrogen sulfide evokes neurite outgrowth and expression of high-voltage-activated Ca2+ currents in NG108-15 cells: involvement of T-type Ca2+ channels. J Neurochem (2008) 0.87

2-Furoyl-LIGRL-NH2, a potent agonist for proteinase-activated receptor-2, as a gastric mucosal cytoprotective agent in mice. Br J Pharmacol (2005) 0.86

Loss of O6-methylguanine-DNA methyltransferase protein expression is a favorable prognostic marker in diffuse large B-cell lymphoma. Int J Hematol (2006) 0.86

Connective tissue growth factor and β-catenin constitute an autocrine loop for activation in rat sarcomatoid mesothelioma. J Pathol (2014) 0.85

Frequent expression of CD30 antigen in the primary gastric non-B, non-Hodgkin lymphomas. Pathol Int (2004) 0.84

Continuous inhibition of epidermal growth factor receptor phosphorylation by erlotinib enhances antitumor activity of chemotherapy in erlotinib-resistant tumor xenografts. Oncol Rep (2011) 0.84

An activation of LC3A-mediated autophagy contributes to de novo and acquired resistance to EGFR tyrosine kinase inhibitors in lung adenocarcinoma. J Pathol (2014) 0.83

Immunohistochemical detection of CD79a expression in precursor T cell lymphoblastic lymphoma/leukaemias. J Pathol (2002) 0.83

Effects of L-arginine on spontaneous contraction of the rat portal vein. Pflugers Arch (2003) 0.83

Differences in osteoclast formation between proximal and distal tibial osteoporosis in rats with adjuvant arthritis: inhibitory effects of bisphosphonates on osteoclasts. Mod Rheumatol (2006) 0.82

Curcumin Inhibits the proteinase-activated receptor-2-triggered prostaglandin E2 production by suppressing cyclooxygenase-2 upregulation and Akt-dependent activation of nuclear factor-κB in human lung epithelial cells. J Pharmacol Sci (2010) 0.82

Evidence that PAR2-triggered prostaglandin E2 (PGE2) formation involves the ERK-cytosolic phospholipase A2-COX-1-microsomal PGE synthase-1 cascade in human lung epithelial cells. Cell Biochem Funct (2008) 0.82

Motif-based search for a novel fructosyl peptide oxidase from genome databases. Biotechnol Bioeng (2010) 0.82

Identification of S100A2 as a target of the DeltaNp63 oncogenic pathway. Clin Cancer Res (2003) 0.82

Distinct activity of peptide mimetic intracellular ligands (pepducins) for proteinase-activated receptor-1 in multiple cells/tissues. Ann N Y Acad Sci (2006) 0.82

Effect of a potent iNOS inhibitor (ONO-1714) on acetaminophen-induced hepatotoxicity in the rat. Life Sci (2003) 0.82

Antitumor activity of bevacizumab in combination with capecitabine and oxaliplatin in human colorectal cancer xenograft models. Oncol Rep (2009) 0.81

Involvement of the endogenous hydrogen sulfide/Ca(v) 3.2 T-type Ca2+ channel pathway in cystitis-related bladder pain in mice. Br J Pharmacol (2012) 0.81

Gene expression profiles of colorectal carcinoma in response to neo-adjuvant chemotherapy. Int J Oncol (2004) 0.81

Rhodanese, but not cystathionine-gamma-lyase, is associated with dextran sulfate sodium-evoked colitis in mice: a sign of impaired colonic sulfide detoxification? Toxicology (2009) 0.81

Antiallodynic effect of etidronate, a bisphosphonate, in rats with adjuvant-induced arthritis: involvement of ATP-sensitive K+ channels. Neuropharmacology (2006) 0.81

Proteinase-activated receptor-2-mediated relaxation in mouse tracheal and bronchial smooth muscle: signal transduction mechanisms and distinct agonist sensitivity. J Pharmacol Exp Ther (2004) 0.81

Quantitative analysis of herpesvirus load in the lymph nodes of patients with histiocytic necrotizing lymphadenitis using a real-time PCR assay. Diagn Mol Pathol (2006) 0.81

Enhancement of capecitabine efficacy by oxaliplatin in human colorectal and gastric cancer xenografts. Oncol Rep (2007) 0.81

Neutralizing antibody evasion ability of adenovirus vector induced by the bioconjugation of methoxypolyethylene glycol succinimidyl propionate (MPEG-SPA). Biol Pharm Bull (2004) 0.80

Proteinase-activated receptor-2-triggered prostaglandin E(2) release, but not cyclooxygenase-2 upregulation, requires activation of the phosphatidylinositol 3-kinase/Akt / nuclear factor-kappaB pathway in human alveolar epithelial cells. J Pharmacol Sci (2009) 0.80

Involvement of Src kinase in T-type calcium channel-dependent neuronal differentiation of NG108-15 cells by hydrogen sulfide. J Neurochem (2010) 0.80

Biomarkers for antitumor activity of bevacizumab in gastric cancer models. BMC Cancer (2012) 0.80

The ferroimmunomodulatory role of ectopic endometriotic stromal cells in ovarian endometriosis. Fertil Steril (2012) 0.80

Development-dependent expression of cyclin D3 in precursor T-cell lymphoblastic leukemia/lymphoma. Pathol Int (2007) 0.80

Stage-specific roles of fibulin-5 during oxidative stress-induced renal carcinogenesis in rats. Free Radic Res (2010) 0.80

Effects of flufenamic acid on smooth muscle of the carotid artery isolated from spontaneously hypertensive rats. J Smooth Muscle Res (2002) 0.79

A novel method for efficient collection of normal mesothelial cells in vivo. J Clin Biochem Nutr (2010) 0.79

Design and synthesis of a peptide-PEG transporter tool for carrying adenovirus vector into cells. Bioorg Med Chem Lett (2005) 0.79

Antihyperalgesic effect of buprenorphine involves nociceptin/orphanin FQ peptide-receptor activation in rats with spinal nerve injury-induced neuropathy. J Pharmacol Sci (2013) 0.79

The PAR-1-activating peptide facilitates pepsinogen secretion in rats. Peptides (2003) 0.79

New information technology tools for a medical command system for mass decontamination. Prehosp Disaster Med (2013) 0.78

Recombinant human soluble thrombomodulin prevents peripheral HMGB1-dependent hyperalgesia in rats. Br J Pharmacol (2013) 0.78

Effect of erythropoietin on human tumor growth in xenograft models. Mol Med Rep (2011) 0.78

Activation of AXL and antitumor effects of a monoclonal antibody to AXL in lung adenocarcinoma. Anticancer Res (2014) 0.78

Signal transduction for formation/release of interleukin-8 caused by a PAR2-activating peptide in human lung epithelial cells. Regul Pept (2007) 0.78

Capecitabine improves cancer cachexia and normalizes IL-6 and PTHrP levels in mouse cancer cachexia models. Cancer Chemother Pharmacol (2006) 0.78

Age- and sun exposure-dependent differences in 8-hydroxy-2'-deoxyguanosine and N-(carboxymethyl)lysine in human epidermis. J Clin Biochem Nutr (2011) 0.78

Cancer-promoting role of adipocytes in asbestos-induced mesothelial carcinogenesis through dysregulated adipocytokine production. Carcinogenesis (2013) 0.78

Involvement of ERK in NMDA receptor-independent cortical neurotoxicity of hydrogen sulfide. Biochem Biophys Res Commun (2011) 0.78

Expression, purification, crystallization and preliminary crystallographic analysis of a deblocking aminopeptidase from Pyrococcus horikoshii. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.78

[Microarray analysis of tumor xenograft model]. Gan To Kagaku Ryoho (2010) 0.77

Plasminogen activator inhibitor-1 is a downstream mediator of the PGP9.5-related oncogenic pathway in esophageal squamous cell carcinoma. Anticancer Res (2005) 0.77

Colonic hydrogen sulfide-induced visceral pain and referred hyperalgesia involve activation of both Ca(v)3.2 and TRPA1 channels in mice. J Pharmacol Sci (2012) 0.77

The proteinase/proteinase-activated receptor-2/transient receptor potential vanilloid-1 cascade impacts pancreatic pain in mice. Life Sci (2010) 0.77

High expression of thymidine phosphorylase in basal-like breast cancers: Stromal expression in EGFR- and/or CK5/6-positive breast cancers. Oncol Lett (2010) 0.77

Stabilization of fungi-derived recombinant FAD-dependent glucose dehydrogenase by introducing a disulfide bond. Biotechnol Lett (2015) 0.77