Efficient production of infectious viruses requires enzymatic activity of Epstein-Barr virus protein kinase.

PubWeight™: 1.13‹?› | Rank: Top 10%

🔗 View Article (PMID 19427010)

Published in Virology on May 08, 2009

Authors

Takayuki Murata1, Hiroki Isomura, Yoriko Yamashita, Shigenori Toyama, Yoshitaka Sato, Sanae Nakayama, Ayumi Kudoh, Satoko Iwahori, Teru Kanda, Tatsuya Tsurumi

Author Affiliations

1: Division of Virology, Aichi Cancer Center Research Institute, 1-1, Kanokoden, Chikusa-ku, Nagoya 464-8681, Japan.

Articles citing this

The Epstein-Barr virus (EBV)-encoded protein kinase, EBV-PK, but not the thymidine kinase (EBV-TK), is required for ganciclovir and acyclovir inhibition of lytic viral production. J Virol (2010) 1.12

Epstein-Barr virus deubiquitinase downregulates TRAF6-mediated NF-κB signaling during productive replication. J Virol (2013) 1.03

Maribavir inhibits epstein-barr virus transcription in addition to viral DNA replication. J Virol (2009) 0.97

Transcriptional repression by sumoylation of Epstein-Barr virus BZLF1 protein correlates with association of histone deacetylase. J Biol Chem (2010) 0.94

Epstein-Barr virus genetics: talking about the BAC generation. Herpesviridae (2010) 0.90

Phosphorylation of p27Kip1 by Epstein-Barr virus protein kinase induces its degradation through SCFSkp2 ubiquitin ligase actions during viral lytic replication. J Biol Chem (2009) 0.89

The Epstein-Barr virus protein kinase BGLF4 and the exonuclease BGLF5 have opposite effects on the regulation of viral protein production. J Virol (2009) 0.89

Tetrameric ring formation of Epstein-Barr virus polymerase processivity factor is crucial for viral replication. J Virol (2010) 0.87

Epstein-Barr virus polymerase processivity factor enhances BALF2 promoter transcription as a coactivator for the BZLF1 immediate-early protein. J Biol Chem (2009) 0.87

Involvement of Jun dimerization protein 2 (JDP2) in the maintenance of Epstein-Barr virus latency. J Biol Chem (2011) 0.86

Hsp90 inhibitor 17-DMAG decreases expression of conserved herpesvirus protein kinases and reduces virus production in Epstein-Barr virus-infected cells. J Virol (2013) 0.85

Simian virus 40 T/t antigens and lamin A/C small interfering RNA rescue the phenotype of an Epstein-Barr virus protein kinase (BGLF4) mutant. J Virol (2010) 0.84

A locus encompassing the Epstein-Barr virus bglf4 kinase regulates expression of genes encoding viral structural proteins. PLoS Pathog (2014) 0.84

Contribution of myocyte enhancer factor 2 family transcription factors to BZLF1 expression in Epstein-Barr virus reactivation from latency. J Virol (2013) 0.83

Epstein-Barr virus BGLF4 kinase downregulates NF-κB transactivation through phosphorylation of coactivator UXT. J Virol (2012) 0.82

Identification and characterization of CCAAT enhancer-binding protein (C/EBP) as a transcriptional activator for Epstein-Barr virus oncogene latent membrane protein 1. J Biol Chem (2011) 0.82

Phosphoproteomic Profiling Reveals Epstein-Barr Virus Protein Kinase Integration of DNA Damage Response and Mitotic Signaling. PLoS Pathog (2015) 0.81

Pin1 interacts with the Epstein-Barr virus DNA polymerase catalytic subunit and regulates viral DNA replication. J Virol (2012) 0.81

Maribavir inhibits Epstein-Barr virus transcription through the EBV protein kinase. J Virol (2013) 0.80

The Epstein-Barr Virus BDLF4 Gene Is Required for Efficient Expression of Viral Late Lytic Genes. J Virol (2015) 0.80

Protein kinase inhibitors that inhibit induction of lytic program and replication of Epstein-Barr virus. Antiviral Res (2012) 0.79

Key motifs in EBV (Epstein-Barr virus)-encoded protein kinase for phosphorylation activity and nuclear localization. Biochem J (2010) 0.79

A Herpesvirus Specific Motif of Epstein-Barr Virus DNA Polymerase Is Required for the Efficient Lytic Genome Synthesis. Sci Rep (2015) 0.78

Induction of Epstein-Barr Virus Oncoprotein LMP1 by Transcription Factors AP-2 and Early B Cell Factor. J Virol (2016) 0.78

Identification of Epstein-Barr Virus Replication Proteins in Burkitt's Lymphoma Cells. Pathogens (2015) 0.75

The UL13 and US3 Protein Kinases of Herpes Simplex Virus 1 Cooperate to Promote the Assembly and Release of Mature, Infectious Virions. PLoS One (2015) 0.75

The C-Terminus of Epstein-Barr Virus BRRF2 Is Required for its Proper Localization and Efficient Virus Production. Front Microbiol (2017) 0.75

Epstein-Barr Virus BKRF4 Gene Product Is Required for Efficient Progeny Production. J Virol (2017) 0.75

Articles by these authors

EB virus-encoded RNAs are recognized by RIG-I and activate signaling to induce type I IFN. EMBO J (2006) 2.51

Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis. Proc Natl Acad Sci U S A (2011) 2.01

Novel narrow-band imaging magnifying endoscopic classification for early gastric cancer. Dig Liver Dis (2010) 1.96

Mitochondrial defect drives non-autonomous tumour progression through Hippo signalling in Drosophila. Nature (2012) 1.95

Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding. J Biol Chem (2004) 1.91

Epstein-Barr virus lytic replication elicits ATM checkpoint signal transduction while providing an S-phase-like cellular environment. J Biol Chem (2004) 1.86

Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infection. J Biol Chem (2005) 1.63

Preclinical study of prolonged administration of trastuzumab as combination therapy after disease progression during trastuzumab monotherapy. Cancer Chemother Pharmacol (2009) 1.52

Latent and lytic Epstein-Barr virus replication strategies. Rev Med Virol (2004) 1.45

Pretreatment with 5-FU enhances cisplatin cytotoxicity in head and neck squamous cell carcinoma cells. Cancer Chemother Pharmacol (2007) 1.41

Reactivation of lytic replication from B cells latently infected with Epstein-Barr virus occurs with high S-phase cyclin-dependent kinase activity while inhibiting cellular DNA replication. J Virol (2003) 1.39

When, where and how the bridge breaks: anaphase bridge breakage plays a crucial role in gene amplification and HSR generation. Exp Cell Res (2005) 1.38

Epstein-Barr virus nuclear protein EBNA3C is required for cell cycle progression and growth maintenance of lymphoblastoid cells. Proc Natl Acad Sci U S A (2006) 1.33

Critical role of Epstein-Barr Virus (EBV)-encoded RNA in efficient EBV-induced B-lymphocyte growth transformation. J Virol (2005) 1.32

A novel function of tissue-type transglutaminase: protein disulphide isomerase. Biochem J (2003) 1.31

Architecture of replication compartments formed during Epstein-Barr virus lytic replication. J Virol (2005) 1.31

Nuclear organization of DNA replication initiation proteins in mammalian cells. J Biol Chem (2002) 1.27

Homologous recombinational repair factors are recruited and loaded onto the viral DNA genome in Epstein-Barr virus replication compartments. J Virol (2009) 1.25

Epstein-Barr virus BZLF1 gene, a switch from latency to lytic infection, is expressed as an immediate-early gene after primary infection of B lymphocytes. J Virol (2006) 1.24

Role of the proximal enhancer of the major immediate-early promoter in human cytomegalovirus replication. J Virol (2004) 1.22

Role of the cytomegalovirus major immediate early enhancer in acute infection and reactivation from latency. Med Microbiol Immunol (2007) 1.20

Mutational inactivation of herpes simplex virus 1 microRNAs identifies viral mRNA targets and reveals phenotypic effects in culture. J Virol (2013) 1.19

ALK+, CD30-, CD20- large B-cell lymphoma containing anaplastic lymphoma kinase (ALK) fused to clathrin heavy chain gene (CLTC). Mod Pathol (2003) 1.15

Inhibition of S-phase cyclin-dependent kinase activity blocks expression of Epstein-Barr virus immediate-early and early genes, preventing viral lytic replication. J Virol (2004) 1.15

Two Sp1/Sp3 binding sites in the major immediate-early proximal enhancer of human cytomegalovirus have a significant role in viral replication. J Virol (2005) 1.13

Phosphorylation of MCM4 at sites inactivating DNA helicase activity of the MCM4-MCM6-MCM7 complex during Epstein-Barr virus productive replication. J Virol (2006) 1.13

Noncanonical TATA sequence in the UL44 late promoter of human cytomegalovirus is required for the accumulation of late viral transcripts. J Virol (2007) 1.13

The human cytomegalovirus gene products essential for late viral gene expression assemble into prereplication complexes before viral DNA replication. J Virol (2011) 1.12

Homozygous deletion of CDKN2A/2B is a hallmark of iron-induced high-grade rat mesothelioma. Lab Invest (2010) 1.12

Bevacizumab improves the delivery and efficacy of paclitaxel. Anticancer Drugs (2010) 1.12

Postreplicative mismatch repair factors are recruited to Epstein-Barr virus replication compartments. J Biol Chem (2006) 1.10

The late promoter of the human cytomegalovirus viral DNA polymerase processivity factor has an impact on delayed early and late viral gene products but not on viral DNA synthesis. J Virol (2007) 1.10

Iron overload signature in chrysotile-induced malignant mesothelioma. J Pathol (2012) 1.08

Epstein-Barr virus nuclear protein EBNA3C residues critical for maintaining lymphoblastoid cell growth. Proc Natl Acad Sci U S A (2009) 1.07

Endoscopic mucosal resection and endoscopic submucosal dissection for esophageal dysplasia and carcinoma. Gastrointest Endosc Clin N Am (2010) 1.05

Degradation of phosphorylated p53 by viral protein-ECS E3 ligase complex. PLoS Pathog (2009) 1.03

Diffuse large B-cell lymphoma initially manifesting in the bone marrow. Am J Clin Pathol (2007) 1.03

Epstein-Barr virus deubiquitinase downregulates TRAF6-mediated NF-κB signaling during productive replication. J Virol (2013) 1.03

CDC6 interaction with ATR regulates activation of a replication checkpoint in higher eukaryotic cells. J Cell Sci (2010) 1.01

In vivo dynamics of EBNA1-oriP interaction during latent and lytic replication of Epstein-Barr virus. J Biol Chem (2004) 1.00

Epstein-Barr virus (EBV)-encoded RNA 2 (EBER2) but not EBER1 plays a critical role in EBV-induced B-cell growth transformation. J Virol (2007) 1.00

Fenton reaction induced cancer in wild type rats recapitulates genomic alterations observed in human cancer. PLoS One (2012) 1.00

Expression of chromobox homolog 7 (CBX7) is associated with poor prognosis in ovarian clear cell adenocarcinoma via TRAIL-induced apoptotic pathway regulation. Int J Cancer (2014) 0.99

Epigenetic histone modification of Epstein-Barr virus BZLF1 promoter during latency and reactivation in Raji cells. J Virol (2012) 0.99

Epstein-Barr virus transforming protein LMP1 plays a critical role in virus production. J Virol (2005) 0.98

A cis element between the TATA Box and the transcription start site of the major immediate-early promoter of human cytomegalovirus determines efficiency of viral replication. J Virol (2007) 0.98

Tetramer-assisted identification and characterization of epitopes recognized by HLA A*2402-restricted Epstein-Barr virus-specific CD8+ T cells. Blood (2002) 0.98

Transcriptional repression by sumoylation of Epstein-Barr virus BZLF1 protein correlates with association of histone deacetylase. J Biol Chem (2010) 0.94

Expression of Epstein-Barr virus BZLF1 immediate-early protein induces p53 degradation independent of MDM2, leading to repression of p53-mediated transcription. Virology (2009) 0.93

In vivo observation of living cancer cells in the esophagus, stomach, and colon using catheter-type contact endoscope, "Endo-Cytoscopy system". Gastrointest Endosc Clin N Am (2004) 0.93

Identification of phosphorylation sites on transcription factor Sp1 in response to DNA damage and its accumulation at damaged sites. Cell Signal (2008) 0.93