PubRank

P Maechler

Author PubWeight™ 21.17‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Functional significance of repressor element 1 silencing transcription factor (REST) target genes in pancreatic beta cells. Diabetologia 2008 1.64
2 Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation. J Biol Chem 2001 1.42
3 Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretion. J Biol Chem 2000 1.41
4 Molecular targets of a human HNF1 alpha mutation responsible for pancreatic beta-cell dysfunction. EMBO J 2000 1.31
5 Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line. EMBO J 1998 1.26
6 Effects of depletion of mitochondrial DNA in metabolism secretion coupling in INS-1 cells. Diabetes 1998 1.17
7 Functional and morphological abnormalities of mitochondria harbouring the tRNA(Leu)(UUR) mutation in mitochondrial DNA derived from patients with maternally inherited diabetes and deafness (MIDD) and progressive kidney disease. Diabetologia 1999 1.06
8 Free radical modulation of insulin release in INS-1 cells exposed to alloxan. Biochem Pharmacol 1999 1.01
9 The dopamine receptor D2 agonist bromocriptine inhibits glucose-stimulated insulin secretion by direct activation of the alpha2-adrenergic receptors in beta cells. Biochem Pharmacol 2010 1.00
10 Mitochondria respond to Ca2+ already in the submicromolar range: correlation with redox state. Cell Calcium 2002 1.00
11 GAD65-mediated glutamate decarboxylation reduces glucose-stimulated insulin secretion in pancreatic beta cells. J Biol Chem 2001 0.99
12 Diabetes-associated mitochondrial DNA mutation A3243G impairs cellular metabolic pathways necessary for beta cell function. Diabetologia 2006 0.96
13 Insulin secretion profiles are modified by overexpression of glutamate dehydrogenase in pancreatic islets. Diabetologia 2003 0.95
14 Peroxisome proliferator-activated receptor alpha (PPARalpha) protects against oleate-induced INS-1E beta cell dysfunction by preserving carbohydrate metabolism. Diabetologia 2009 0.94
15 Reactive oxygen metabolites increase mitochondrial calcium in endothelial cells: implication of the Ca2+/Na+ exchanger. J Cell Sci 1999 0.92
16 A high carbohydrate diet does not induce hyperglycaemia in a mitochondrial glycerol-3-phosphate dehydrogenase-deficient mouse. Diabetologia 2003 0.90
17 The importance of redox shuttles to pancreatic beta-cell energy metabolism and function. Biochem Soc Trans 2006 0.89
18 Mitochondrial calcium oscillations in C2C12 myotubes. J Biol Chem 2000 0.85
19 Dopamine modulates von Willebrand factor secretion in endothelial cells via D2-D4 receptors. J Thromb Haemost 2006 0.82
20 Sustained glucose-stimulated insulin secretion in mouse islets is not culture-dependent. Diabetologia 2004 0.80
21 Studies on the human plasma kallikrein-kinin system: alpha-kallikrein does not directly activate blood neutrophils. Thromb Res 1989 0.75