Published in Adv Drug Deliv Rev on November 13, 2009
The blood-testis barrier and its implications for male contraception. Pharmacol Rev (2011) 2.10
HIV-associated neurocognitive disorder. Lancet Infect Dis (2013) 1.60
Analyses of nanoformulated antiretroviral drug charge, size, shape and content for uptake, drug release and antiviral activities in human monocyte-derived macrophages. J Control Release (2010) 1.28
Overcoming pharmacologic sanctuaries. Curr Opin HIV AIDS (2013) 1.17
The potential of magneto-electric nanocarriers for drug delivery. Expert Opin Drug Deliv (2014) 1.09
Engineered nanomaterials: exposures, hazards, and risk prevention. J Occup Med Toxicol (2011) 1.05
Progress in antiretroviral drug delivery using nanotechnology. Int J Nanomedicine (2010) 1.04
Gene therapy for the nervous system: challenges and new strategies. Neurotherapeutics (2014) 0.98
Getting into the brain: Potential of nanotechnology in the management of NeuroAIDS. Adv Drug Deliv Rev (2016) 0.98
Toward eradicating HIV reservoirs in the brain: inhibiting P-glycoprotein at the blood-brain barrier with prodrug abacavir dimers. J Am Chem Soc (2011) 0.96
Development of HIV reservoir targeted long acting nanoformulated antiretroviral therapies. Curr Med Chem (2014) 0.94
Nano-NRTIs: efficient inhibitors of HIV type-1 in macrophages with a reduced mitochondrial toxicity. Antivir Chem Chemother (2010) 0.94
Microscopy and tunable resistive pulse sensing characterization of the swelling of pH-responsive, polymeric expansile nanoparticles. Nanoscale (2013) 0.94
Towards nanomedicines for neuroAIDS. Rev Med Virol (2014) 0.94
Anti-HIV-1 nanotherapeutics: promises and challenges for the future. Int J Nanomedicine (2012) 0.88
Effect of human immunodeficiency virus on blood-brain barrier integrity and function: an update. Front Cell Neurosci (2015) 0.87
Influence of charge on FITC-BSA-loaded chondroitin sulfate-chitosan nanoparticles upon cell uptake in human Caco-2 cell monolayers. Int J Nanomedicine (2012) 0.86
Nanotechnology and the treatment of HIV infection. Viruses (2012) 0.84
Drug delivery strategies and systems for HIV/AIDS pre-exposure prophylaxis and treatment. J Control Release (2015) 0.83
Advances in Integrative Nanomedicine for Improving Infectious Disease Treatment in Public Health. Eur J Integr Med (2013) 0.81
Drug synergy of tenofovir and nanoparticle-based antiretrovirals for HIV prophylaxis. PLoS One (2013) 0.81
Nanoparticle-based drug delivery to improve the efficacy of antiretroviral therapy in the central nervous system. Int J Nanomedicine (2014) 0.81
Efficacy of Tat-conjugated ritonavir-loaded nanoparticles in reducing HIV-1 replication in monocyte-derived macrophages and cytocompatibility with macrophages and human neurons. AIDS Res Hum Retroviruses (2011) 0.80
The comparison of protein-entrapped liposomes and lipoparticles: preparation, characterization, and efficacy of cellular uptake. Int J Nanomedicine (2011) 0.79
Nanomaterials in controlled drug release. Cytotechnology (2011) 0.78
Preparation, characterization, and safety evaluation of poly(lactide-co-glycolide) nanoparticles for protein delivery into macrophages. Int J Nanomedicine (2015) 0.77
HIV-associated neurocognitive disorders: perspective on management strategies. Drugs (2013) 0.77
Prevention, Rehabilitation, and Mitigation Strategies of Cognitive Deficits in Aging with HIV: Implications for Practice and Research. ISRN Nurs (2013) 0.77
Antidepressant effects of curcumin and HU-211 coencapsulated solid lipid nanoparticles against corticosterone-induced cellular and animal models of major depression. Int J Nanomedicine (2016) 0.75
Targeting ischemic penumbra Part II: selective drug delivery using liposome technologies. J Exp Stroke Transl Med (2011) 0.75
Inhibition of HIV Virus by Neutralizing Vhh Attached to Dual Functional Liposomes Encapsulating Dapivirine. Nanoscale Res Lett (2016) 0.75
Second Generation Amphiphilic Poly-Lysine Dendrons Inhibit Glioblastoma Cell Proliferation without Toxicity for Neurons or Astrocytes. PLoS One (2016) 0.75
Brain-targeted delivery of resveratrol using solid lipid nanoparticles functionalized with apolipoprotein E. J Nanobiotechnology (2016) 0.75
Development of antibody-modified chitosan nanoparticles for the targeted delivery of siRNA across the blood-brain barrier as a strategy for inhibiting HIV replication in astrocytes. Drug Deliv Transl Res (2017) 0.75
The complexities of antiretroviral drug-drug interactions: role of ABC and SLC transporters. Trends Pharmacol Sci (2009) 1.62
A mechanistic study of enhanced doxorubicin uptake and retention in multidrug resistant breast cancer cells using a polymer-lipid hybrid nanoparticle system. J Pharmacol Exp Ther (2006) 1.59
Chemotherapy with anticancer drugs encapsulated in solid lipid nanoparticles. Adv Drug Deliv Rev (2007) 1.48
A new polymer-lipid hybrid nanoparticle system increases cytotoxicity of doxorubicin against multidrug-resistant human breast cancer cells. Pharm Res (2006) 1.44
Functional expression and localization of P-glycoprotein in the central nervous system: relevance to the pathogenesis and treatment of neurological disorders. Pharm Res (2004) 1.38
Multidrug resistance-associated proteins: expression and function in the central nervous system. Pharmacol Rev (2006) 1.33
Medicinal and recreational marijuana use by patients infected with HIV. AIDS Patient Care STDS (2004) 1.20
Simultaneous delivery of doxorubicin and GG918 (Elacridar) by new polymer-lipid hybrid nanoparticles (PLN) for enhanced treatment of multidrug-resistant breast cancer. J Control Release (2006) 1.18
Classification of cell types using a microfluidic device for mechanical and electrical measurement on single cells. Lab Chip (2011) 1.15
Use of complementary and alternative medicine by HIV-infected outpatients in Ontario, Canada. AIDS Patient Care STDS (2003) 1.14
Up-regulation of P-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line. J Neurosci Res (2009) 1.14
HIV-1 viral envelope glycoprotein gp120 triggers an inflammatory response in cultured rat astrocytes and regulates the functional expression of P-glycoprotein. Mol Pharmacol (2006) 1.13
Optimized digital counting colonies of clonogenic assays using ImageJ software and customized macros: comparison with manual counting. Int J Radiat Biol (2011) 1.09
HIV-1 viral envelope glycoprotein gp120 produces oxidative stress and regulates the functional expression of multidrug resistance protein-1 (Mrp1) in glial cells. J Neurochem (2008) 1.06
Functional expression of the multidrug resistance protein 1 in microglia. J Pharmacol Exp Ther (2003) 1.05
Nanotechnological advances for the delivery of CNS therapeutics. Adv Drug Deliv Rev (2011) 1.03
Regulation of multidrug resistance protein 1 by tumor necrosis factor alpha in cultured glial cells: involvement of nuclear factor-kappaB and c-Jun N-terminal kinase signaling pathways. Mol Pharmacol (2010) 1.03
Development of solid lipid nanoparticles containing ionically complexed chemotherapeutic drugs and chemosensitizers. J Pharm Sci (2004) 1.02
Solid lipid nanoparticles enhance the delivery of the HIV protease inhibitor, atazanavir, by a human brain endothelial cell line. Pharm Res (2008) 1.02
Temperature and pH-responsive polymeric composite membranes for controlled delivery of proteins and peptides. Biomaterials (2004) 1.01
Regulation of P-glycoprotein by orphan nuclear receptors in human brain microvessel endothelial cells. J Neurochem (2011) 1.00
Expression of ATP-binding cassette membrane transporters in rodent and human sertoli cells: relevance to the permeability of antiretroviral therapy at the blood-testis barrier. J Pharmacol Exp Ther (2011) 1.00
Regulation of ABC membrane transporters in glial cells: relevance to the pharmacotherapy of brain HIV-1 infection. Glia (2008) 0.99
Regulation of breast cancer resistant protein by peroxisome proliferator-activated receptor α in human brain microvessel endothelial cells. Mol Pharmacol (2012) 0.98
Cellular localization and functional expression of P-glycoprotein in rat astrocyte cultures. J Neurochem (2004) 0.98
Modulated insulin permeation across a glucose-sensitive polymeric composite membrane. J Control Release (2002) 0.97
Expression of the ATP-binding cassette membrane transporter, ABCG2, in human and rodent brain microvessel endothelial and glial cell culture systems. Pharm Res (2007) 0.96
Multidrug resistance protein (MRP) 4- and MRP 5-mediated efflux of 9-(2-phosphonylmethoxyethyl)adenine by microglia. J Pharmacol Exp Ther (2004) 0.95
Role of P-glycoprotein in the distribution of the HIV protease inhibitor atazanavir in the brain and male genital tract. Antimicrob Agents Chemother (2013) 0.91
pH dependence of organic anion-transporting polypeptide 2B1 in Caco-2 cells: potential role in antiretroviral drug oral bioavailability and drug-drug interactions. J Pharmacol Exp Ther (2010) 0.90
A novel solid lipid nanoparticle formulation for active targeting to tumor α(v) β(3) integrin receptors reveals cyclic RGD as a double-edged sword. Adv Healthc Mater (2012) 0.90
Targeting colloidal particulates to thoracic lymph nodes. Lung Cancer (2006) 0.89
Investigation of mechanical properties of soft hydrogel microcapsules in relation to protein delivery using a MEMS force sensor. J Biomed Mater Res A (2010) 0.88
Differential role of organic anion-transporting polypeptides in estrone-3-sulphate uptake by breast epithelial cells and breast cancer cells. J Pharmacol Exp Ther (2012) 0.88
In vitro and in vivo testing of glucose-responsive insulin-delivery microdevices in diabetic rats. Lab Chip (2012) 0.88
Longitudinal trends in antiretroviral use in a cohort of men and women in Ontario, Canada. AIDS Patient Care STDS (2006) 0.87
Involvement of P-glycoprotein in the transport of saquinavir and indinavir in rat brain microvessel endothelial and microglia cell lines. Pharm Res (2004) 0.87
Multidrug resistance protein 1-mediated transport of saquinavir by microglia. Neuroreport (2004) 0.86
Drug loading onto ion-exchange microspheres: modeling study and experimental verification. Biomaterials (2006) 0.86
Colloidally stable silicon nanocrystals with near-infrared photoluminescence for biological fluorescence imaging. Small (2011) 0.86
Design and characterization of HER-2-targeted gold nanoparticles for enhanced X-radiation treatment of locally advanced breast cancer. Mol Pharm (2010) 0.86
"HIV isn't me…": HIV+ adolescents' experiences in a positive context of support and treatment. AIDS Care (2011) 0.85
Polypharmacy in HIV: impact of data source and gender on reported drug utilization. AIDS Patient Care STDS (2004) 0.85
Molecular interactions, internal structure and drug release kinetics of rationally developed polymer-lipid hybrid nanoparticles. J Control Release (2008) 0.85
Expression of membrane drug efflux transporters in the sigmoid colon of HIV-infected and uninfected men. J Clin Pharmacol (2013) 0.84
On the stability of insulin delivered through a new glucose-responsive polymeric composite membrane. J Pharm Pharmacol (2004) 0.84
In vivo evaluation of a new polymer-lipid hybrid nanoparticle (PLN) formulation of doxorubicin in a murine solid tumor model. Eur J Pharm Biopharm (2006) 0.84
Interactions between phytochemical components of Sutherlandia frutescens and the antiretroviral, atazanavir in vitro: implications for absorption and metabolism. J Pharm Pharm Sci (2012) 0.84
Regulation of P-glycoprotein by human immunodeficiency virus-1 in primary cultures of human fetal astrocytes. J Neurosci Res (2011) 0.84
A multifunctional polymeric nanotheranostic system delivers doxorubicin and imaging agents across the blood-brain barrier targeting brain metastases of breast cancer. ACS Nano (2014) 0.84
Delivery of an anticancer drug and a chemosensitizer to murine breast sarcoma by intratumoral injection of sulfopropyl dextran microspheres. J Pharm Pharmacol (2003) 0.84
Localization of P-glycoprotein at the nuclear envelope of rat brain cells. Biochem Biophys Res Commun (2007) 0.84
Multifunctional albumin-MnO₂ nanoparticles modulate solid tumor microenvironment by attenuating hypoxia, acidosis, vascular endothelial growth factor and enhance radiation response. ACS Nano (2014) 0.83
In vivo induction of P-glycoprotein expression at the mouse blood-brain barrier: an intracerebral microdialysis study. J Neurochem (2013) 0.82
Screening of lipid carriers and characterization of drug-polymer-lipid interactions for the rational design of polymer-lipid hybrid nanoparticles (PLN). Pharm Res (2006) 0.81
Evaluation of copolymers of N-isopropylacrylamide and 2-dimethyl(aminoethyl)methacrylate in nonviral and adenoviral vectors for gene delivery to nasopharyngeal carcinoma. Int J Nanomedicine (2007) 0.81
Molecular and functional characterization of P-glycoprotein in vitro. Methods Mol Biol (2011) 0.81
Hybrid quantum dot-fatty ester stealth nanoparticles: toward clinically relevant in vivo optical imaging of deep tissue. ACS Nano (2011) 0.81
Role of drug efflux and uptake transporters in atazanavir intestinal permeability and drug-drug interactions. Pharm Res (2012) 0.81
Immobilization and bioactivity of glucose oxidase in hydrogel microspheres formulated by an emulsification-internal gelation-adsorption-polyelectrolyte coating method. Int J Pharm (2007) 0.81
A novel doxorubicin-mitomycin C co-encapsulated nanoparticle formulation exhibits anti-cancer synergy in multidrug resistant human breast cancer cells. Breast Cancer Res Treat (2009) 0.80
Prediction of kinetics of doxorubicin release from sulfopropyl dextran ion-exchange microspheres using artificial neural networks. Eur J Pharm Sci (2005) 0.80
Estrone-3-sulphate, a potential novel ligand for targeting breast cancers. PLoS One (2013) 0.80
1α,25-Dihydroxyvitamin D3-liganded vitamin D receptor increases expression and transport activity of P-glycoprotein in isolated rat brain capillaries and human and rat brain microvessel endothelial cells. J Neurochem (2012) 0.80
A new approach to the in vivo and in vitro investigation of drug release from locoregionally delivered microspheres. J Control Release (2004) 0.80
Role of nuclear receptors in the regulation of drug transporters in the brain. Trends Pharmacol Sci (2013) 0.79
RGD-conjugated solid lipid nanoparticles inhibit adhesion and invasion of αvβ3 integrin-overexpressing breast cancer cells. Drug Deliv Transl Res (2015) 0.79
Immune tolerance properties of the testicular tissue as a viral sanctuary site in ART-treated HIV-infected adults. AIDS (2016) 0.79
Research Advances in the Intervention of Inflammation and Cancer by Active Ingredients of Traditional Chinese Medicine. J Pharm Pharm Sci (2016) 0.78
pH-Dependent doxorubicin release from terpolymer of starch, polymethacrylic acid and polysorbate 80 nanoparticles for overcoming multi-drug resistance in human breast cancer cells. Eur J Pharm Biopharm (2012) 0.78
On the synergistic effect of doxorubicin and mitomycin C against breast cancer cells. Drug Metabol Drug Interact (2007) 0.78
Microdomain pH gradient and kinetics inside composite polymeric membranes of pH and glucose sensitivity. Pharm Res (2007) 0.78
Matrigel alters the pathophysiology of orthotopic human breast adenocarcinoma xenografts with implications for nanomedicine evaluation. Nanomedicine (2013) 0.78
Drug transporters at brain barriers: expression and regulation by neurological disorders. Adv Exp Med Biol (2012) 0.78
Investigation of the effects of cell model and subcellular location of gold nanoparticles on nuclear dose enhancement factors using Monte Carlo simulation. Med Phys (2013) 0.78
Induction of P-glycoprotein by antiretroviral drugs in human brain microvessel endothelial cells. Antimicrob Agents Chemother (2013) 0.78
Thermally-triggered 'off-on-off' response of gadolinium-hydrogel-lipid hybrid nanoparticles defines a customizable temperature window for non-invasive magnetic resonance imaging thermometry. J Control Release (2011) 0.77
Cytotoxicity and mechanism of action of a new ROS-generating microsphere formulation for circumventing multidrug resistance in breast cancer cells. Breast Cancer Res Treat (2009) 0.77
Doxorubicin and mitomycin C co-loaded polymer-lipid hybrid nanoparticles inhibit growth of sensitive and multidrug resistant human mammary tumor xenografts. Cancer Lett (2012) 0.77
In vitro toxicity to breast cancer cells of microsphere-delivered mitomycin C and its combination with doxorubicin. Eur J Pharm Biopharm (2005) 0.77
Characterization of complexation of poly (N-isopropylacrylamide-co-2-(dimethylamino) ethyl methacrylate) thermoresponsive cationic nanogels with salmon sperm DNA. Int J Nanomedicine (2009) 0.77
A novel nanoparticle formulation overcomes multiple types of membrane efflux pumps in human breast cancer cells. Drug Deliv Transl Res (2012) 0.77
In vivo performance and biocompatibility of a subcutaneous implant for real-time glucose-responsive insulin delivery. Diabetes Technol Ther (2015) 0.76
Synergistic nanoparticulate drug combination overcomes multidrug resistance, increases efficacy, and reduces cardiotoxicity in a nonimmunocompromised breast tumor model. Mol Pharm (2014) 0.76
Multifunctional terpolymeric MRI contrast agent with superior signal enhancement in blood and tumor. J Control Release (2013) 0.76
Design of pH-responsive nanoparticles of terpolymer of poly(methacrylic acid), polysorbate 80 and starch for delivery of doxorubicin. Colloids Surf B Biointerfaces (2012) 0.76
Characterization of a microsphere formulation containing glucose oxidase and its in vivo efficacy in a murine solid tumor model. Pharm Res (2009) 0.76
Highly effective and recyclable dendritic ligands for the enantioselective aryl transfer reactions to aldehydes. J Org Chem (2005) 0.76
Expression of membrane transporters and metabolic enzymes involved in estrone-3-sulphate disposition in human breast tumour tissues. Breast Cancer Res Treat (2014) 0.76