Published in Toxicon on November 18, 2009
Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel. Elife (2013) 1.31
Profiling the venom gland transcriptomes of Costa Rican snakes by 454 pyrosequencing. BMC Genomics (2011) 1.09
Hg1, novel peptide inhibitor specific for Kv1.3 channels from first scorpion Kunitz-type potassium channel toxin family. J Biol Chem (2012) 1.07
Comparative venom gland transcriptome analysis of the scorpion Lychas mucronatus reveals intraspecific toxic gene diversity and new venomous components. BMC Genomics (2010) 1.05
Unique scorpion toxin with a putative ancestral fold provides insight into evolution of the inhibitor cystine knot motif. Proc Natl Acad Sci U S A (2011) 1.01
Tinnitus: network pathophysiology-network pharmacology. Front Syst Neurosci (2012) 0.99
Evolution stings: the origin and diversification of scorpion toxin peptide scaffolds. Toxins (Basel) (2013) 0.97
Scorpion sting nephropathy. NDT Plus (2011) 0.91
New tricks of an old pattern: structural versatility of scorpion toxins with common cysteine spacing. J Biol Chem (2012) 0.91
Purification, molecular cloning and functional characterization of HelaTx1 (Heterometrus laoticus): the first member of a new κ-KTX subfamily. Biochem Pharmacol (2012) 0.86
Mass fingerprinting of the venom and transcriptome of venom gland of scorpion Centruroides tecomanus. PLoS One (2013) 0.85
Variability of Potassium Channel Blockers in Mesobuthus eupeus Scorpion Venom with Focus on Kv1.1: AN INTEGRATED TRANSCRIPTOMIC AND PROTEOMIC STUDY. J Biol Chem (2015) 0.84
Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders. BMC Genomics (2014) 0.83
Functional evolution of scorpion venom peptides with an inhibitor cystine knot fold. Biosci Rep (2013) 0.83
Transcriptome analysis of scorpion species belonging to the Vaejovis genus. PLoS One (2015) 0.82
Whole Transcriptome of the Venom Gland from Urodacus yaschenkoi Scorpion. PLoS One (2015) 0.82
Genomic and structural characterization of Kunitz-type peptide LmKTT-1a highlights diversity and evolution of scorpion potassium channel toxins. PLoS One (2013) 0.81
Dissecting a role of evolutionary-conserved but noncritical disulfide bridges in cysteine-rich peptides using ω-conotoxin GVIA and its selenocysteine analogs. Biopolymers (2012) 0.81
Overview of scorpion species from China and their toxins. Toxins (Basel) (2014) 0.79
Scorpions from Mexico: From Species Diversity to Venom Complexity. Toxins (Basel) (2015) 0.79
Toxin acidic residue evolutionary function-guided design of de novo peptide drugs for the immunotherapeutic target, the Kv1.3 channel. Sci Rep (2015) 0.79
Insights into the venom composition and evolution of an endoparasitoid wasp by combining proteomic and transcriptomic analyses. Sci Rep (2016) 0.78
Mass landscapes of seven scorpion species: The first analyses of Australian species with 1,5-DAN matrix. J Venom Res (2012) 0.78
Intraspecific variation of centruroides edwardsii venom from two regions of Colombia. Toxins (Basel) (2014) 0.77
The Mediterranean scorpion Mesobuthus gibbosus (Scorpiones, Buthidae): transcriptome analysis and organization of the genome encoding chlorotoxin-like peptides. BMC Genomics (2014) 0.77
Genetic and morphological analyses indicate that the Australian endemic scorpion Urodacus yaschenkoi (Scorpiones: Urodacidae) is a species complex. PeerJ (2017) 0.75
Melt With This Kiss: Paralyzing and Liquefying Venom of The Assassin Bug Pristhesancus plagipennis (Hemiptera: Reduviidae). Mol Cell Proteomics (2017) 0.75
The Biochemical Toxin Arsenal from Ant Venoms. Toxins (Basel) (2016) 0.75
Electrophysiological Characterization of the Antarease Metalloprotease from Tityus serrulatus Venom. Toxins (Basel) (2017) 0.75
Current views on scorpion toxins specific for K+-channels. Toxicon (2004) 2.60
Novel interactions between K+ channels and scorpion toxins. Trends Pharmacol Sci (2003) 1.91
Overview of scorpion toxins specific for Na+ channels and related peptides: biodiversity, structure-function relationships and evolution. Toxicon (2005) 1.67
Occurrence of tetrodotoxin and its analogues in the Brazilian frog Brachycephalus ephippium (Anura: Brachycephalidae). Toxicon (2002) 1.21
Mapping the binding site of a human ether-a-go-go-related gene-specific peptide toxin (ErgTx) to the channel's outer vestibule. J Biol Chem (2002) 1.13
Transcriptome analysis of the venom gland of the Mexican scorpion Hadrurus gertschi (Arachnida: Scorpiones). BMC Genomics (2007) 1.12
Venom proteomic and venomous glands transcriptomic analysis of the Egyptian scorpion Scorpio maurus palmatus (Arachnida: Scorpionidae). Toxicon (2013) 1.00
Oxyopinins, large amphipathic peptides isolated from the venom of the wolf spider Oxyopes kitabensis with cytolytic properties and positive insecticidal cooperativity with spider neurotoxins. J Biol Chem (2002) 0.99
An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways. Pain (2013) 0.98
The Brazilian scorpion Tityus costatus Karsch: genes, peptides and function. Toxicon (2004) 0.97
Cloning and characterization of cDNA sequences encoding for new venom peptides of the Brazilian scorpion Opisthacanthus cayaporum. Toxicon (2009) 0.97
Characterization of venom components from the scorpion Androctonus crassicauda of Turkey: peptides and genes. Toxicon (2006) 0.96
Characterization of hadrucalcin, a peptide from Hadrurus gertschi scorpion venom with pharmacological activity on ryanodine receptors. Br J Pharmacol (2009) 0.96
Characterization of the venom from the Australian scorpion Urodacus yaschenkoi: Molecular mass analysis of components, cDNA sequences and peptides with antimicrobial activity. Toxicon (2012) 0.96
Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels. J Biol Chem (2009) 0.96
Vm24, a natural immunosuppressive peptide, potently and selectively blocks Kv1.3 potassium channels of human T cells. Mol Pharmacol (2012) 0.96
Four disulfide-bridged scorpion beta neurotoxin CssII: heterologous expression and proper folding in vitro. Biochim Biophys Acta (2007) 0.95
Resurgent current and voltage sensor trapping enhanced activation by a beta-scorpion toxin solely in Nav1.6 channel. Significance in mice Purkinje neurons. J Biol Chem (2006) 0.94
Mapping the receptor site for ergtoxin, a specific blocker of ERG channels. FEBS Lett (2002) 0.93
Activation of skeletal ryanodine receptors by two novel scorpion toxins from Buthotus judaicus. J Biol Chem (2004) 0.92
Novel paradigms on scorpion toxins that affects the activating mechanism of sodium channels. Toxicon (2006) 0.91
Toxin gamma from Tityus serrulatus scorpion venom plays an essential role in immunomodulation of macrophages. Toxicon (2007) 0.91
A large number of novel Ergtoxin-like genes and ERG K+-channels blocking peptides from scorpions of the genus Centruroides. FEBS Lett (2002) 0.90
Mass spectrometry analysis, amino acid sequence and biological activity of venom components from the Brazilian scorpion Opisthacanthus cayaporum. Toxicon (2008) 0.90
Two novel toxins from the Amazonian scorpion Tityus cambridgei that block Kv1.3 and Shaker B K(+)-channels with distinctly different affinities. Biochim Biophys Acta (2002) 0.90
General biochemical and immunological characterization of the venom from the scorpion Tityus trivittatus of Argentina. Toxicon (2009) 0.90
Species diversity and peptide toxins blocking selectivity of ether-a-go-go-related gene subfamily K+ channels in the central nervous system. Mol Pharmacol (2006) 0.90
Wide phylogenetic distribution of Scorpine and long-chain beta-KTx-like peptides in scorpion venoms: identification of "orphan" components. Peptides (2006) 0.90
Global transcriptome analysis of the scorpion Centruroides noxius: new toxin families and evolutionary insights from an ancestral scorpion species. PLoS One (2012) 0.89
Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors. FEBS J (2007) 0.89
An insecticidal peptide from the theraposid Brachypelma smithi spider venom reveals common molecular features among spider species from different genera. Peptides (2008) 0.89
The change of the scFv into the Fab format improves the stability and in vivo toxin neutralization capacity of recombinant antibodies. Mol Immunol (2006) 0.89
On the evolution of invertebrate defensins. Trends Genet (2005) 0.88
Further report of the occurrence of tetrodotoxin and new analogues in the Anuran family Brachycephalidae. Toxicon (2005) 0.88
Imperatoxin A, a Cell-Penetrating Peptide from Scorpion Venom, as a Probe of Ca-Release Channels/Ryanodine Receptors. Pharmaceuticals (Basel) (2010) 0.88
Structure, function, and chemical synthesis of Vaejovis mexicanus peptide 24: a novel potent blocker of Kv1.3 potassium channels of human T lymphocytes. Biochemistry (2012) 0.88
Venom from the centipede Scolopendra viridis Say: purification, gene cloning and phylogenetic analysis of a phospholipase A2. Toxicon (2009) 0.88
Isolation of a long-lasting eag-related gene-type K+ current in MMQ lactotrophs and its accommodating role during slow firing and prolactin release. J Neurosci (2002) 0.87
The Cuban scorpion Rhopalurus junceus (Scorpiones, Buthidae): component variations in venom samples collected in different geographical areas. J Venom Anim Toxins Incl Trop Dis (2013) 0.87
Molecular cloning and nucleotide sequence analysis of genes from a cDNA library of the scorpion Tityus discrepans. Biochimie (2009) 0.86
Proteomic analysis of Tityus discrepans scorpion venom and amino acid sequence of novel toxins. Proteomics (2006) 0.86
Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins. J Chromatogr B Analyt Technol Biomed Life Sci (2004) 0.86
Insecticidal peptides from the theraposid spider Brachypelma albiceps: an NMR-based model of Ba2. Biochim Biophys Acta (2009) 0.86
Scorpion beta-toxins and voltage-gated sodium channels: interactions and effects. Front Biosci (Landmark Ed) (2013) 0.86
Two new scorpion toxins that target voltage-gated Ca2+ and Na+ channels. Biochem Biophys Res Commun (2002) 0.86
Immunology of scorpion toxins and perspectives for generation of anti-venom vaccines. Vaccine (2005) 0.85
Mass fingerprinting of the venom and transcriptome of venom gland of scorpion Centruroides tecomanus. PLoS One (2013) 0.85
Expanding the scorpion toxin alpha-KTX 15 family with AmmTX3 from Androctonus mauretanicus. Eur J Biochem (2002) 0.85
NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical beta-toxin sequence but with alpha-like physiological activity. Eur J Biochem (2004) 0.85
Gene cloning and functional characterization of four novel antimicrobial-like peptides from scorpions of the family Vaejovidae. Peptides (2012) 0.84
Anuroctoxin, a new scorpion toxin of the alpha-KTx 6 subfamily, is highly selective for Kv1.3 over IKCa1 ion channels of human T lymphocytes. Mol Pharmacol (2004) 0.84
A selective blocker of Kv1.2 and Kv1.3 potassium channels from the venom of the scorpion Centruroides suffusus suffusus. Biochem Pharmacol (2008) 0.84
Negative-shift activation, current reduction and resurgent currents induced by β-toxins from Centruroides scorpions in sodium channels. Toxicon (2011) 0.83
A novel conotoxin from Conus delessertii with posttranslationally modified lysine residues. Biochemistry (2005) 0.83
Exploiting cross-reactivity to neutralize two different scorpion venoms with one single chain antibody fragment. J Biol Chem (2010) 0.83
Addition of positive charges at the C-terminal peptide region of CssII, a mammalian scorpion peptide toxin, improves its affinity for sodium channels Nav1.6. Peptides (2010) 0.82
Phaiodactylipin, a glycosylated heterodimeric phospholipase A from the venom of the scorpion Anuroctonus phaiodactylus. Eur J Biochem (2004) 0.82
Biochemical, genetic and physiological characterization of venom components from two species of scorpions: Centruroides exilicauda Wood and Centruroides sculpturatus Ewing. Biochimie (2004) 0.82
MeuTXKbeta1, a scorpion venom-derived two-domain potassium channel toxin-like peptide with cytolytic activity. Biochim Biophys Acta (2010) 0.82
HgeTx1, the first K+-channel specific toxin characterized from the venom of the scorpion Hadrurus gertschi Soleglad. Toxicon (2006) 0.82
Disulfide bridges and blockage of Shaker B K(+)-channels by another butantoxin peptide purified from the Argentinean scorpion Tityus trivittatus. Toxicon (2003) 0.82
Novel alpha-KTx peptides from the venom of the scorpion Centruroides elegans selectively blockade Kv1.3 over IKCa1 K+ channels of T cells. Toxicon (2005) 0.81
Purification of a specific inhibitor of pyroglutamyl aminopeptidase II from the marine annelide Hermodice carunculata. in vivo effects in rodent brain. Int J Biochem Cell Biol (2004) 0.81
Vejovine, a new antibiotic from the scorpion venom of Vaejovis mexicanus. Toxicon (2010) 0.81
A novel toxin from the venom of the scorpion Tityus trivittatus, is the first member of a new alpha-KTX subfamily. FEBS Lett (2006) 0.81
Structural basis of neutralization of the major toxic component from the scorpion Centruroides noxius Hoffmann by a human-derived single-chain antibody fragment. J Biol Chem (2011) 0.81
Proteomic analysis of the venom from the fish eating coral snake Micrurus surinamensis: novel toxins, their function and phylogeny. Proteomics (2008) 0.81
Isolation and molecular cloning of beta-neurotoxins from the venom of the scorpion Centruroides suffusus suffusus. Toxicon (2011) 0.81
A subfamily of acidic alpha-K(+) toxins. J Biol Chem (2003) 0.81
Isolation and characterization of a novel toxin from the venom of the spider Grammostola rosea that blocks sodium channels. Toxicon (2007) 0.81
Molecular cloning and biochemical characterization of the first Na(+)-channel α-type toxin peptide (Acra4) from Androctonus crassicauda scorpion venom. Biochimie (2013) 0.80
A single mutation in framework 2 of the heavy variable domain improves the properties of a diabody and a related single-chain antibody. J Mol Biol (2012) 0.80
Ability of suramin to antagonize the cardiotoxic and some enzymatic activities of Bothrops jararacussu venom. Toxicon (2007) 0.80
Bites caused by giant water bugs belonging to Belostomatidae family (Hemiptera, Heteroptera) in humans: a report of seven cases. Wilderness Environ Med (2010) 0.80
Proteomic analysis of the venom and characterization of toxins specific for Na+ - and K+ -channels from the Colombian scorpion Tityus pachyurus. Biochim Biophys Acta (2005) 0.80
Cn11, the first example of a scorpion toxin that is a true blocker of Na(+) currents in crayfish neurons. J Exp Biol (2002) 0.80
Antimicrobial peptides from arachnid venoms and their microbicidal activity in the presence of commercial antibiotics. J Antibiot (Tokyo) (2012) 0.80
A Conus regularis conotoxin with a novel eight-cysteine framework inhibits CaV2.2 channels and displays an anti-nociceptive activity. Mar Drugs (2013) 0.80
Enhanced antimicrobial activity of novel synthetic peptides derived from vejovine and hadrurin. Biochim Biophys Acta (2013) 0.80
Identification, cDNA cloning and heterologous expression of a hyaluronidase from the tarantula Brachypelma vagans venom. Toxicon (2012) 0.79
Venomic and pharmacological activity of Acanthoscurria paulensis (Theraphosidae) spider venom. Toxicon (2012) 0.79
Tst26, a novel peptide blocker of Kv1.2 and Kv1.3 channels from the venom of Tityus stigmurus. Toxicon (2009) 0.79
Precursor De13.1 from Conus delessertii defines the novel G gene superfamily. Peptides (2013) 0.79
Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion Centruroides suffusus suffusus, and their effects on Nav1.5 sodium channels. Biochim Biophys Acta (2012) 0.79
Phaiodotoxin, a novel structural class of insect-toxin isolated from the venom of the Mexican scorpion Anuroctonus phaiodactylus. Eur J Biochem (2004) 0.79
A toxic fraction from scolopendra venom increases the basal release of neurotransmitters in the ventral ganglia of crustaceans. Comp Biochem Physiol C Toxicol Pharmacol (2003) 0.79
Protease inhibitors from marine venomous animals and their counterparts in terrestrial venomous animals. Mar Drugs (2013) 0.79
Inhibition of the collapse of the Shaker K+ conductance by specific scorpion toxins. J Gen Physiol (2004) 0.78
Heterologous expressed toxic and non-toxic peptide variants of toxin CssII are capable to produce neutralizing antibodies against the venom of the scorpion Centruroides suffusus suffusus. Immunol Lett (2009) 0.78
Antimicrobial peptide from the skin secretion of the frog Leptodactylus syphax. Toxicon (2007) 0.78
A novel human recombinant antibody fragment capable of neutralizing Mexican scorpion toxins. Toxicon (2013) 0.78
Analysis of the immune response induced by a scorpion venom sub-fraction, a pure peptide and a recombinant peptide, against toxin Cn2 of Centruroides noxius Hoffmann. Toxicon (2003) 0.78
Isolation and characterization of a human antibody fragment specific for Ts1 toxin from Tityus serrulatus scorpion. Immunol Lett (2011) 0.78
Identification and phylogenetic analysis of Tityus pachyurus and Tityus obscurus novel putative Na+-channel scorpion toxins. PLoS One (2012) 0.78