Published in Proc Natl Acad Sci U S A on November 23, 2009
Conversion of the chill susceptible fruit fly larva (Drosophila melanogaster) to a freeze tolerant organism. Proc Natl Acad Sci U S A (2012) 1.06
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Antifreeze proteins in the Antarctic springtail, Gressittacantha terranova. J Comp Physiol B (2011) 0.75
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Ice-active proteins and cryoprotectants from the New Zealand alpine cockroach, Celatoblatta quinquemaculata. J Insect Physiol (2008) 0.81
Freeze tolerance in an arctic Alaska stonefly. J Exp Biol (2009) 0.81
Hibernation in black bears: independence of metabolic suppression from body temperature. Science (2011) 2.27
Regulation of UCP1 and UCP3 in arctic ground squirrels and relation with mitochondrial proton leak. J Appl Physiol (1985) (2006) 1.56
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Central nervous system regulation of mammalian hibernation: implications for metabolic suppression and ischemia tolerance. J Neurochem (2007) 1.41
Modulation of gene expression in hibernating arctic ground squirrels. Physiol Genomics (2007) 1.31
Cloning and characterization of a thermal hysteresis (antifreeze) protein with DNA-binding activity from winter bittersweet nightshade, Solanum dulcamara. Plant Mol Biol (2002) 1.26
Correlated C-C and C-O bond conformations in saccharide hydroxymethyl groups: parametrization and application of redundant 1H-1H, 13C-1H, and 13C-13C NMR J-couplings. J Am Chem Soc (2004) 1.23
Shotgun proteomics analysis of hibernating arctic ground squirrels. Mol Cell Proteomics (2009) 1.20
Modification of proteins in vitro by physiological levels of glucose: pyridoxamine inhibits conversion of Amadori intermediate to advanced glycation end-products through binding of redox metal ions. J Biol Chem (2003) 1.18
Absence of cellular stress in brain after hypoxia induced by arousal from hibernation in Arctic ground squirrels. Am J Physiol Regul Integr Comp Physiol (2005) 1.16
Phenological variation in annual timing of hibernation and breeding in nearby populations of Arctic ground squirrels. Proc Biol Sci (2010) 1.15
Detection of differential gene expression in brown adipose tissue of hibernating arctic ground squirrels with mouse microarrays. Physiol Genomics (2006) 1.13
Energetics of arousal episodes in hibernating arctic ground squirrels. J Comp Physiol B (2009) 1.11
Metabolic rate and prehibernation fattening in free-living arctic ground squirrels. Physiol Biochem Zool (2013) 1.09
Daily body temperature rhythms persist under the midnight sun but are absent during hibernation in free-living arctic ground squirrels. Biol Lett (2011) 1.08
Pyridoxamine protects proteins from functional damage by 3-deoxyglucosone: mechanism of action of pyridoxamine. Biochemistry (2007) 1.05
Elevated expression of protein biosynthesis genes in liver and muscle of hibernating black bears (Ursus americanus). Physiol Genomics (2009) 1.03
Annual rhythms that underlie phenology: biological time-keeping meets environmental change. Proc Biol Sci (2013) 1.03
Modulation of gene expression in heart and liver of hibernating black bears (Ursus americanus). BMC Genomics (2011) 1.02
Androgen in free-living arctic ground squirrels: seasonal changes and influence of staged male-male aggressive encounters. Horm Behav (2003) 1.02
Comparative overwintering physiology of Alaska and Indiana populations of the beetle Cucujus clavipes (Fabricius): roles of antifreeze proteins, polyols, dehydration and diapause. J Exp Biol (2005) 1.00
Data logging of body temperatures provides precise information on phenology of reproductive events in a free-living Arctic hibernator. J Comp Physiol B (2011) 0.99
Genomic analysis of miRNAs in an extreme mammalian hibernator, the Arctic ground squirrel. Physiol Genomics (2010) 0.98
A test of alternative models for increased tissue nitrogen isotope ratios during fasting in hibernating arctic ground squirrels. J Exp Biol (2012) 0.98
Long-range protein-water dynamics in hyperactive insect antifreeze proteins. Proc Natl Acad Sci U S A (2012) 0.97
Thermoregulatory changes anticipate hibernation onset by 45 days: data from free-living arctic ground squirrels. J Comp Physiol B (2012) 0.96
Antifreeze proteins of the beetle Dendroides canadensis enhance one another's activities. Biochemistry (2005) 0.95
Hibernation and circadian rhythms of body temperature in free-living Arctic ground squirrels. Physiol Biochem Zool (2012) 0.95
Animal activity around the clock with no overt circadian rhythms: patterns, mechanisms and adaptive value. Proc Biol Sci (2013) 0.93
Expression of an insect (Dendroides canadensis) antifreeze protein in Arabidopsis thaliana results in a decrease in plant freezing temperature. Plant Mol Biol (2002) 0.93
Tissue-specific depression of mitochondrial proton leak and substrate oxidation in hibernating arctic ground squirrels. Am J Physiol Regul Integr Comp Physiol (2003) 0.92
Polycarboxylates enhance beetle antifreeze protein activity. Biochim Biophys Acta (2008) 0.92
Effects of polyhydroxy compounds on beetle antifreeze protein activity. Biochim Biophys Acta (2008) 0.92
Conformational analysis of beta-glycosidic linkages in 13C-labeled glucobiosides using inter-residue scalar coupling constants. J Phys Chem B (2008) 0.92
The physiological link between metabolic rate depression and tau phosphorylation in mammalian hibernation. PLoS One (2011) 0.91
Arginine, a key residue for the enhancing ability of an antifreeze protein of the beetle Dendroides canadensis. Biochemistry (2009) 0.90
3-Deoxy-beta-D-ribo-hexopyranose (3-deoxy-beta-D-glucopyranose). Acta Crystallogr C (2007) 0.90
Genomic analysis of expressed sequence tags in American black bear Ursus americanus. BMC Genomics (2010) 0.89
Geminal 2JCCH spin-spin coupling constants as probes of the phi glycosidic torsion angle in oligosaccharides. J Am Chem Soc (2005) 0.87
DFT and NMR studies of 2JCOH, 3JHCOH, and 3JCCOH spin-couplings in saccharides: C-O torsional bias and H-bonding in aqueous solution. J Org Chem (2007) 0.86
1JCH correlates with alcohol hydrogen bond strength. J Org Chem (2006) 0.86
A thaumatin-like protein from larvae of the beetle Dendroides canadensis enhances the activity of antifreeze proteins. Biochemistry (2006) 0.85
Lessons from nature for preservation of mammalian cells, tissues, and organs. In Vitro Cell Dev Biol Anim (2010) 0.84
[13C,15N]2-Acetamido-2-deoxy-D-aldohexoses and their methyl glycosides: synthesis and NMR investigations of J-couplings involving 1H, 13C, and 15N. J Org Chem (2006) 0.84
4J(COCCH) and 4J(CCCCH) as probes of exocyclic hydroxymethyl group conformation in saccharides. J Org Chem (2005) 0.84
Hibernating above the permafrost: effects of ambient temperature and season on expression of metabolic genes in liver and brown adipose tissue of arctic ground squirrels. J Exp Biol (2011) 0.84
Molecular signatures of mammalian hibernation: comparisons with alternative phenotypes. BMC Genomics (2013) 0.84
Changing seasonality and phenological responses of free-living male arctic ground squirrels: the importance of sex. Philos Trans R Soc Lond B Biol Sci (2013) 0.83
Dependence of pyranose ring puckering on anomeric configuration: methyl idopyranosides. J Phys Chem B (2012) 0.82
Proteomic Profiling Reveals Adaptive Responses to Surgical Myocardial Ischemia-Reperfusion in Hibernating Arctic Ground Squirrels Compared to Rats. Anesthesiology (2016) 0.81
Informing saccharide structural NMR studies with density functional theory calculations. Methods Mol Biol (2015) 0.81
4-Deoxy-4-fluoro-β-D-glucopyranose. Acta Crystallogr C (2010) 0.81
13C-13C NMR spin-spin coupling constants in saccharides: structural correlations involving all carbons in aldohexopyranosyl rings. J Org Chem (2007) 0.81
Dietary fatty acid composition and the hibernation patterns in free-ranging arctic ground squirrels. Physiol Biochem Zool (2008) 0.81
Freeze tolerance in an arctic Alaska stonefly. J Exp Biol (2009) 0.81
An NMR investigation of putative interresidue H-bonding in methyl alpha-cellobioside in solution. Carbohydr Res (2009) 0.81
Rearrangement of 3-deoxy-D-erythro-hexos-2-ulose in aqueous solution: NMR evidence of intramolecular 1,2-hydrogen transfer. J Org Chem (2011) 0.80
Comparative functional genomics of adaptation to muscular disuse in hibernating mammals. Mol Ecol (2014) 0.80
N-acetyl side-chains in saccharides: NMR J-coupling equations sensitive to CH-NH and NH-CO bond conformations in 2-acetamido-2-deoxy-aldohexopyranosyl rings. J Org Chem (2010) 0.79
Overwintering physiology and microhabitat use of Phyllocnistis populiella (Lepidoptera: Gracilliariidae) in interior Alaska. Environ Entomol (2012) 0.79
A thermal hysteresis-producing xylomannan glycolipid antifreeze associated with cold tolerance is found in diverse taxa. J Comp Physiol B (2011) 0.78
Thermoregulation and energetics in hibernating black bears: metabolic rate and the mystery of multi-day body temperature cycles. J Comp Physiol B (2015) 0.78
Cryoprotectant biosynthesis and the selective accumulation of threitol in the freeze-tolerant Alaskan beetle, Upis ceramboides. J Biol Chem (2009) 0.78
(13)C-(1)H and (13)C-(13)C NMR J-couplings in (13)C-labeled N-acetyl-neuraminic acid: correlations with molecular structure. J Org Chem (2008) 0.78
Methyl 2-acetamido-2-deoxy-β-D-glucopyranoside dihydrate and methyl 2-formamido-2-deoxy-β-D-glucopyranoside. Acta Crystallogr C (2011) 0.78
Preservation of bone mass and structure in hibernating black bears (Ursus americanus) through elevated expression of anabolic genes. Funct Integr Genomics (2012) 0.78
Arctic Ground Squirrels Limit Bone Loss during the Prolonged Physical Inactivity Associated with Hibernation. Physiol Biochem Zool (2015) 0.78
A cross-species compendium of proteins/gene products related to cold stress identified by bioinformatic approaches. J Insect Physiol (2011) 0.78
O-Acetyl Side-Chains in Monosaccharides: Redundant NMR Spin-Couplings and Statistical Models for Acetate Ester Conformational Analysis. J Phys Chem B (2016) 0.78
Estimating lean mass over a wide range of body composition: a calibration of deuterium dilution in the arctic ground squirrel. Rapid Commun Mass Spectrom (2011) 0.77
Oligosaccharide trans-glycoside 3JCOCC Karplus curves are not equivalent: effect of internal electronegative substituents. J Org Chem (2008) 0.77
Expression of a beetle, Dendroides canadensis, antifreeze protein in Drosophila melanogaster. J Insect Physiol (2006) 0.77
PHF-like tau phosphorylation in mammalian hibernation is not associated with p25-formation. J Neural Transm (Vienna) (2009) 0.77
Elucidating the biochemical overwintering adaptations of Larval Cucujus clavipes puniceus, a nonmodel organism, via high throughput proteomics. J Proteome Res (2011) 0.77
Methyl 4-O-β-D-mannopyranosyl β-D-xylopyranoside. Acta Crystallogr C (2012) 0.77
Cryoprotectant Production in Freeze-Tolerant Wood Frogs Is Augmented by Multiple Freeze-Thaw Cycles. Physiol Biochem Zool (2016) 0.77
Disorder and conformational analysis of methyl β-D-galactopyranosyl-(1→4)-β-D-xylopyranoside. Acta Crystallogr C (2011) 0.76
Methyl 4-O-beta-D-galactopyranosyl alpha-D-mannopyranoside methanol 0.375-solvate. Acta Crystallogr C (2010) 0.76
Methyl 4-O-β-D-xylopyranosyl β-D-mannopyranoside, a core disaccharide of an antifreeze glycolipid. Acta Crystallogr C (2013) 0.76
Methyl beta-D-galactopyranosyl-(1-->4)-beta-D-allopyranoside tetrahydrate. Acta Crystallogr C (2010) 0.76
Methyl 4-O-beta-D-galactopyranosyl alpha-D-glucopyranoside (methyl alpha-lactoside). Acta Crystallogr C (2005) 0.76
Amide cis-trans isomerization in aqueous solutions of methyl N-formyl-D-glucosaminides and methyl N-acetyl-D-glucosaminides: chemical equilibria and exchange kinetics. J Am Chem Soc (2010) 0.76
Antifreeze proteins in the primary urine of larvae of the beetle Dendroides canadensis. J Exp Biol (2013) 0.76
13C-labeled N-acetyl-neuraminic acid in aqueous solution: detection and quantification of acyclic keto, keto hydrate, and enol forms by 13C NMR spectroscopy. J Am Chem Soc (2008) 0.76
Cloning, sequence analysis and phylogeny of connexin43 isolated from American black bear heart. DNA Seq (2007) 0.76
Expression of two self-enhancing antifreeze proteins from the beetle Dendroides canadensis in Drosophila melanogaster. J Insect Physiol (2009) 0.76