Besides CYP2C19*2, the variant allele CYP2C9*3 is associated with higher on-clopidogrel platelet reactivity in patients on dual antiplatelet therapy undergoing elective coronary stent implantation.

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Published in Pharmacogenet Genomics on January 01, 2010

Authors

Ankie Harmsze1, Jochem W van Werkum, Heleen J Bouman, Henk J Ruven, Nicolien J Breet, Jurrien M Ten Berg, Christian M Hackeng, Mathieu M Tjoeng, Olaf H Klungel, Anthonius de Boer, Vera H Deneer

Author Affiliations

1: Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, The Netherlands.

Associated clinical trials:

Cost-effectiveness of Genotype Guided Treatment With Antiplatelet Drugs in STEMI Patients: Optimization of Treatment (POPGenetics) | NCT01761786

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