Loading and maintenance dose algorithms for phenprocoumon and acenocoumarol using patient characteristics and pharmacogenetic data.

PubWeight™: 1.07‹?› | Rank: Top 10%

🔗 View Article (PMID 21636598)

Published in Eur Heart J on June 02, 2011

Authors

Rianne M F van Schie1, Judith A M Wessels, Saskia le Cessie, Anthonius de Boer, Tom Schalekamp, Felix J M van der Meer, Talitha I Verhoef, Erik van Meegen, Frits R Rosendaal, Anke-Hilse Maitland-van der Zee, EU-PACT Study Group

Author Affiliations

1: Study coordinating Centre, Department of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, PO Box 80 082, 3508 TB Utrecht, The Netherlands.

Associated clinical trials:

EUropean Pharmacogenetics of AntiCoagulant Therapy - Warfarin (EU-PACT) | NCT01119300

EUropean Pharmacogenetics of AntiCoagulant Therapy - Acenocoumarol (EU-PACT) | NCT01119261

EUropean Pharmacogenetics of AntiCoagulant Therapy - Phenprocoumon (EU-PACT) | NCT01119274

Articles citing this

Pharmacogenetic-guided dosing of coumarin anticoagulants: algorithms for warfarin, acenocoumarol and phenprocoumon. Br J Clin Pharmacol (2014) 0.97

Therapeutic dosing of acenocoumarol: proposal of a population specific pharmacogenetic dosing algorithm and its validation in north Indians. PLoS One (2012) 0.84

The effect of omeprazole and esomeprazole on the maintenance dose of phenprocoumon. Br J Clin Pharmacol (2012) 0.84

An acenocoumarol dosing algorithm using clinical and pharmacogenetic data in Spanish patients with thromboembolic disease. PLoS One (2012) 0.82

Efficiency and effectiveness of the use of an acenocoumarol pharmacogenetic dosing algorithm versus usual care in patients with venous thromboembolic disease initiating oral anticoagulation: study protocol for a randomized controlled trial. Trials (2012) 0.79

Pharmacogenetics aspects of oral anticoagulants therapy. J Med Life (2015) 0.79

Comparison of Nine Statistical Model Based Warfarin Pharmacogenetic Dosing Algorithms Using the Racially Diverse International Warfarin Pharmacogenetic Consortium Cohort Database. PLoS One (2015) 0.78

An acenocoumarol dose algorithm based on a South-Eastern European population. Eur J Clin Pharmacol (2013) 0.76

Novel associations of VKORC1 variants with higher acenocoumarol requirements. PLoS One (2013) 0.75

Evaluation of a pharmacogenetic-based warfarin dosing algorithm in patients with low time in therapeutic range - study protocol for a randomized controlled trial. BMC Cardiovasc Disord (2016) 0.75

A New Pharmacogenetic Algorithm to Predict the Most Appropriate Dosage of Acenocoumarol for Stable Anticoagulation in a Mixed Spanish Population. PLoS One (2016) 0.75

Articles by these authors

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10

Malignancies, prothrombotic mutations, and the risk of venous thrombosis. JAMA (2005) 6.16

How to diagnose rheumatoid arthritis early: a prediction model for persistent (erosive) arthritis. Arthritis Rheum (2002) 5.33

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet (2012) 4.87

Preoperative anaemia and postoperative outcomes in non-cardiac surgery: a retrospective cohort study. Lancet (2011) 4.27

A randomized trial of genotype-guided dosing of acenocoumarol and phenprocoumon. N Engl J Med (2013) 4.27

Association of genetic variations with nonfatal venous thrombosis in postmenopausal women. JAMA (2007) 3.50

Estrogen plus progestin and risk of venous thrombosis. JAMA (2004) 3.46

Risk assessment for recurrent venous thrombosis. Lancet (2010) 3.31

A prediction rule for disease outcome in patients with recent-onset undifferentiated arthritis: how to guide individual treatment decisions. Arthritis Rheum (2007) 3.23

Evaluation of short-term consequences of hypoglycemia in an intensive care unit. Crit Care Med (2006) 3.13

Long-term impact of delay in assessment of patients with early arthritis. Arthritis Rheum (2010) 3.08

Thrombophilia, clinical factors, and recurrent venous thrombotic events. JAMA (2005) 3.04

Instrumental variables: application and limitations. Epidemiology (2006) 3.03

Prevention of venous thromboembolism after major orthopaedic surgery: is fondaparinux an advance? Lancet (2003) 2.98

Cardiovascular and noncardiovascular mortality among patients starting dialysis. JAMA (2009) 2.85

Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: A randomized, placebo-controlled, double-blind trial. Blood (2006) 2.78

Predisposing factors for hypoglycemia in the intensive care unit. Crit Care Med (2006) 2.75

Gene variants associated with deep vein thrombosis. JAMA (2008) 2.74

Osteoarthritis of the knee: association between clinical features and MR imaging findings. Radiology (2006) 2.62

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet (2012) 2.53

Relationship between single nucleotide polymorphisms and haplotypes in DPYD and toxicity and efficacy of capecitabine in advanced colorectal cancer. Clin Cancer Res (2011) 2.52

Use of Framingham risk score and new biomarkers to predict cardiovascular mortality in older people: population based observational cohort study. BMJ (2009) 2.46

Different combined oral contraceptives and the risk of venous thrombosis: systematic review and network meta-analysis. BMJ (2013) 2.45

Hypoglycemia is associated with intensive care unit mortality. Crit Care Med (2010) 2.41

Antiphospholipid antibodies and risk of myocardial infarction and ischaemic stroke in young women in the RATIO study: a case-control study. Lancet Neurol (2009) 2.37

A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset rheumatoid arthritis. Arthritis Rheum (2007) 2.36

Combined oral contraceptives: venous thrombosis. Cochrane Database Syst Rev (2014) 2.28

Etiology, management, and outcome of the Budd-Chiari syndrome. Ann Intern Med (2009) 2.26

VKORC1 and CYP2C9 genotypes and acenocoumarol anticoagulation status: interaction between both genotypes affects overanticoagulation. Clin Pharmacol Ther (2006) 2.19

Optimal level of oral anticoagulant therapy for the prevention of arterial thrombosis in patients with mechanical heart valve prostheses, atrial fibrillation, or myocardial infarction: a prospective study of 4202 patients. Arch Intern Med (2009) 2.16

A diagnostic rule for the aetiology of lower respiratory tract infections as guidance for antimicrobial treatment. Br J Gen Pract (2004) 2.15

Interaction between the Gly460Trp alpha-adducin gene variant and diuretics on the risk of myocardial infarction. J Hypertens (2009) 2.14

A national field study of quality assessment of CoaguChek point-of-care testing prothrombin time monitors. Am J Clin Pathol (2006) 2.09

Risks of oral anticoagulant therapy with increasing age. Arch Intern Med (2005) 2.06

CYP2C19*2 and CYP2C9*3 alleles are associated with stent thrombosis: a case-control study. Eur Heart J (2010) 2.00

Lowering the intensity of oral anticoagulant therapy: effects on the risk of hemorrhage and thromboembolism. Arch Intern Med (2004) 2.00

Is an EMA review on hormonal contraception and thrombosis needed? BMJ (2013) 1.94

Smoking increases the risk of venous thrombosis and acts synergistically with oral contraceptive use. Am J Hematol (2008) 1.93

Risk of hip/femur fracture after stroke: a population-based case-control study. Stroke (2009) 1.88

Obesity: risk of venous thrombosis and the interaction with coagulation factor levels and oral contraceptive use. Thromb Haemost (2003) 1.80

High VWF, low ADAMTS13, and oral contraceptives increase the risk of ischemic stroke and myocardial infarction in young women. Blood (2011) 1.78

Incidence and risk factors of early venous thrombosis associated with permanent pacemaker leads. J Cardiovasc Electrophysiol (2004) 1.72

Statins and prevention of infections: systematic review and meta-analysis of data from large randomised placebo controlled trials. BMJ (2011) 1.72

Multiple SNP testing improves risk prediction of first venous thrombosis. Blood (2012) 1.70

Esterified estrogens and conjugated equine estrogens and the risk of venous thrombosis. JAMA (2004) 1.70

Serum lipid levels and the risk of venous thrombosis. Arterioscler Thromb Vasc Biol (2004) 1.69

Timing of acute myocardial infarction in patients undergoing total hip or knee replacement: a nationwide cohort study. Arch Intern Med (2012) 1.66

Patterns of interaction between genetic and nongenetic attributes and methotrexate efficacy in rheumatoid arthritis. Pharmacogenet Genomics (2012) 1.65

Changes in mortality patterns following total hip or knee arthroplasty over the past two decades: a nationwide cohort study. Arthritis Rheumatol (2014) 1.61

Risk of venous thrombosis: obesity and its joint effect with oral contraceptive use and prothrombotic mutations. Br J Haematol (2007) 1.61

Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity. J Clin Oncol (2009) 1.60

Effects of cytochrome P450 2C9 polymorphisms on phenprocoumon anticoagulation status. Clin Pharmacol Ther (2004) 1.60

Rate and determinants of 10-year persistence with antihypertensive drugs. J Hypertens (2005) 1.58

Genetic polymorphisms associated with a prolonged progression-free survival in patients with metastatic renal cell cancer treated with sunitinib. Clin Cancer Res (2010) 1.57

Smoking and the risk of mortality and vascular and respiratory events in patients undergoing major surgery. JAMA Surg (2013) 1.57

Determinants of survival and the effect of portosystemic shunting in patients with Budd-Chiari syndrome. Hepatology (2004) 1.57

Influence of dietary vitamin K intake on subtherapeutic oral anticoagulant therapy. Br J Haematol (2010) 1.55

Use of oral glucocorticoids and the risk of pulmonary embolism: a population-based case-control study. Chest (2013) 1.55

Nutritional management of the gluten-free diet in young people with celiac disease in The Netherlands. J Pediatr Gastroenterol Nutr (2006) 1.52

Levels of intrinsic coagulation factors and the risk of myocardial infarction among men: Opposite and synergistic effects of factors XI and XII. Blood (2006) 1.52

The effect of flight-related behaviour on the risk of venous thrombosis after air travel. Br J Haematol (2008) 1.50

Venous thrombosis and conjugated equine estrogen in women without a uterus. Arch Intern Med (2006) 1.50

Variation in Renin-Angiotensin system and salt-sensitivity genes and the risk of diabetes mellitus associated with the use of thiazide diuretics. Am J Hypertens (2009) 1.50

Prevention of coagulase-negative staphylococcal central venous catheter-related infection using urokinase rinses: a randomized double-blind controlled trial in patients with hematologic malignancies. J Clin Oncol (2008) 1.49

Effect of oral antiplatelet agents on major bleeding in users of coumarins. Thromb Haemost (2008) 1.48

Mutations in clotting factors and inflammatory bowel disease. Am J Gastroenterol (2006) 1.47

The risk of venous thrombosis in individuals with a history of superficial vein thrombosis and acquired venous thrombotic risk factors. Blood (2013) 1.47

Immunosuppressants and alloimmunization against red blood cell transfusions. Transfusion (2014) 1.47

Generic substitution of antihypertensive drugs: does it affect adherence? Ann Pharmacother (2005) 1.47

A multicentre randomised assessment of the DAWN AC computer-assisted oral anticoagulant dosage program. Thromb Haemost (2009) 1.46

Genetic variation in the fibrinogen gamma gene increases the risk for deep venous thrombosis by reducing plasma fibrinogen gamma' levels. Blood (2005) 1.46

Subtherapeutic oral anticoagulant therapy: frequency and risk factors. Thromb Haemost (2009) 1.46

The HLA-DRB1 shared epitope alleles differ in the interaction with smoking and predisposition to antibodies to cyclic citrullinated peptide. Arthritis Rheum (2007) 1.46

Food questionnaire for the assessment of gluten intake by children 1 to 4 years old. J Pediatr Gastroenterol Nutr (2012) 1.44

Effectiveness of HMG-CoA reductase inhibitors is modified by the ACE insertion deletion polymorphism. Atherosclerosis (2004) 1.43

Bleeding in carriers of hemophilia. Blood (2006) 1.41

Factor V Leiden, prothrombin G20210A, and risk of sudden coronary death in apparently healthy persons. Am J Cardiol (2002) 1.41

Quality assessment of CoaguChek point-of-care prothrombin time monitors: comparison of the European community-approved procedure and conventional external quality assessment. Clin Chem (2006) 1.40

Prothrombotic gene variation in patients with large and small vessel disease. Neuroepidemiology (2008) 1.40

Fluid loss does not explain coagulation activation during air travel. Thromb Haemost (2008) 1.38

Familial longevity is marked by enhanced insulin sensitivity. Aging Cell (2010) 1.32

F8 gene mutation type and inhibitor development in patients with severe hemophilia A: systematic review and meta-analysis. Blood (2012) 1.31

Increased bleeding risk with concurrent use of selective serotonin reuptake inhibitors and coumarins. Arch Intern Med (2008) 1.30

Long-term risk of cardiovascular disease after treatment for aggressive non-Hodgkin lymphoma. Blood (2005) 1.28