Relevant B cell epitopes in allergic disease.

PubWeight™: 1.08‹?› | Rank: Top 10%

🔗 View Article (PMC 2956005)

Published in Int Arch Allergy Immunol on November 26, 2009

Authors

Anna Pomés1

Author Affiliations

1: Indoor Biotechnologies, Inc., Charlottesville, Va., USA. apomes@inbio.com

Articles citing this

Molecular mimicry between cockroach and helminth glutathione S-transferases promotes cross-reactivity and cross-sensitization. J Allergy Clin Immunol (2012) 1.58

Identification of conformational B-cell Epitopes in an antigen from its primary sequence. Immunome Res (2010) 1.45

Immunoinformatics: an integrated scenario. Immunology (2010) 0.94

The human IgE repertoire. Int Arch Allergy Immunol (2013) 0.94

Allergic sensitization: screening methods. Clin Transl Allergy (2014) 0.89

Structure of allergens and structure based epitope predictions. Methods (2013) 0.86

In Silico Prediction of T and B Cell Epitopes of Der f 25 in Dermatophagoides farinae. Int J Genomics (2014) 0.83

Analysis of the effects of polymorphism on pollen profilin structural functionality and the generation of conformational, T- and B-cell epitopes. PLoS One (2013) 0.81

Identification of critical amino acids in an immunodominant IgE epitope of Pen c 13, a major allergen from Penicillium citrinum. PLoS One (2012) 0.81

Strategies to query and display allergy-derived epitope data from the immune epitope database. Int Arch Allergy Immunol (2012) 0.80

In silico identification of IgE-binding epitopes of osmotin protein. PLoS One (2013) 0.80

Serum autoantibodies to myelin peptides distinguish acute disseminated encephalomyelitis from relapsing-remitting multiple sclerosis. Mult Scler (2013) 0.80

Epitope mapping and in silico characterization of interactions between Der p 7 allergen and MoAb WH9. PLoS One (2013) 0.78

Purification, Cloning and Immuno-Biochemical Characterization of a Fungal Aspartic Protease Allergen Rhi o 1 from the Airborne Mold Rhizopus oryzae. PLoS One (2015) 0.78

Conformational IgE epitopes of peanut allergens Ara h 2 and Ara h 6. Clin Exp Allergy (2016) 0.77

Persistence and evolution of allergen-specific IgE repertoires during subcutaneous specific immunotherapy. J Allergy Clin Immunol (2015) 0.77

Epitope mapping of monoclonal antibodies for the Deinococcus radiodurans bacteriophytochome. Protein Sci (2014) 0.77

Molecular cloning, expression, IgE binding activities and in silico epitope prediction of Per a 9 allergens of the American cockroach. Int J Mol Med (2016) 0.77

Preparation and identification of Per a 5 as a novel American cockroach allergen. Mediators Inflamm (2014) 0.77

The impact of structural integrity and route of administration on the antibody specificity against three cow's milk allergens - a study in Brown Norway rats. Clin Transl Allergy (2014) 0.75

In silico epitope prediction, expression and functional analysis of Per a 10 allergen from the American cockroach. Int J Mol Med (2016) 0.75

Epitope Mapping of Rhi o 1 and Generation of a Hypoallergenic Variant: A CANDIDATE MOLECULE FOR FUNGAL ALLERGY VACCINES. J Biol Chem (2016) 0.75

Articles cited by this

Cation-pi interactions in structural biology. Proc Natl Acad Sci U S A (1999) 6.88

Three-dimensional structure of an antigen-antibody complex at 2.8 A resolution. Science (1986) 4.94

Three-dimensional structure of an antibody-antigen complex. Proc Natl Acad Sci U S A (1987) 3.48

Epitopes on protein antigens: misconceptions and realities. Cell (1990) 3.32

Prediction of residues in discontinuous B-cell epitopes using protein 3D structures. Protein Sci (2006) 3.06

Discriminating between homodimeric and monomeric proteins in the crystalline state. Proteins (2000) 2.96

Structure of an antibody-antigen complex: crystal structure of the HyHEL-10 Fab-lysozyme complex. Proc Natl Acad Sci U S A (1989) 2.65

Several distinct properties of the IgE repertoire determine effector cell degranulation in response to allergen challenge. J Allergy Clin Immunol (2008) 2.37

ElliPro: a new structure-based tool for the prediction of antibody epitopes. BMC Bioinformatics (2008) 2.26

CEP: a conformational epitope prediction server. Nucleic Acids Res (2005) 2.14

Immunological speculations. Annu Rev Microbiol (1960) 1.98

Structural biology of allergens. J Allergy Clin Immunol (2000) 1.67

X-ray crystallography of antibodies. Adv Protein Chem (1996) 1.49

Dominant epitopes and allergic cross-reactivity: complex formation between a Fab fragment of a monoclonal murine IgG antibody and the major allergen from birch pollen Bet v 1. J Immunol (2000) 1.46

Specificity of IgE antibodies to sequential epitopes of hen's egg ovomucoid as a marker for persistence of egg allergy. Allergy (2007) 1.41

Peanut epitopes for IgE and IgG4 in peanut-sensitized children in relation to severity of peanut allergy. J Allergy Clin Immunol (2008) 1.39

High-affinity IgE recognition of a conformational epitope of the major respiratory allergen Phl p 2 as revealed by X-ray crystallography. J Immunol (2009) 1.37

Crystal structure of a dimerized cockroach allergen Bla g 2 complexed with a monoclonal antibody. J Biol Chem (2008) 1.35

Molecular interactions between a recombinant IgE antibody and the beta-lactoglobulin allergen. Structure (2007) 1.33

Specific IgE and IgG antibody-binding patterns to recombinant cockroach allergens. J Allergy Clin Immunol (2005) 1.33

Structure of the major peanut allergen Ara h 1 may protect IgE-binding epitopes from degradation. J Immunol (2000) 1.26

Dominating IgE-binding epitope of Bet v 1, the major allergen of birch pollen, characterized by X-ray crystallography and site-directed mutagenesis. J Immunol (2003) 1.25

Molecular cloning of a major cockroach (Blattella germanica) allergen, Bla g 2. Sequence homology to the aspartic proteases. J Biol Chem (1995) 1.23

Dimerization of the major birch pollen allergen Bet v 1 is important for its in vivo IgE-cross-linking potential in mice. J Immunol (2005) 1.22

Conformational stability of B cell epitopes on group I and group II Dermatophagoides spp. allergens. Effect of thermal and chemical denaturation on the binding of murine IgG and human IgE antibodies. J Immunol (1990) 1.17

Crystal structure of cockroach allergen Bla g 2, an unusual zinc binding aspartic protease with a novel mode of self-inhibition. J Mol Biol (2005) 1.15

Allermatch, a webtool for the prediction of potential allergenicity according to current FAO/WHO Codex alimentarius guidelines. BMC Bioinformatics (2004) 1.14

Cockroach allergen Bla g 2: structure, function, and implications for allergic sensitization. Am J Respir Crit Care Med (2002) 1.11

Evolutionary distance from human homologs reflects allergenicity of animal food proteins. J Allergy Clin Immunol (2007) 1.11

Genetic engineering of a hypoallergenic trimer of the major birch pollen allergen Bet v 1. FASEB J (2001) 1.08

Identification of a B-cell epitope of hyaluronidase, a major bee venom allergen, from its crystal structure in complex with a specific Fab. J Mol Biol (2007) 1.06

Epitope mapping of two major inhalant allergens, Der p I and Der f I, from mites of the genus Dermatophagoides. J Immunol (1987) 1.03

Crystal structures of mite allergens Der f 1 and Der p 1 reveal differences in surface-exposed residues that may influence antibody binding. J Mol Biol (2008) 1.03

Cockroach allergen Bla g 2: an unusual aspartic proteinase. J Allergy Clin Immunol (2005) 1.01

Crystal structure of the allergen Equ c 1. A dimeric lipocalin with restricted IgE-reactive epitopes. J Biol Chem (2000) 0.98

Conserved sequence and structure association motifs in antibody-protein and antibody-hapten complexes. Protein Eng Des Sel (2004) 0.97

Nuclear magnetic resonance structure and IgE epitopes of Blo t 5, a major dust mite allergen. J Immunol (2008) 0.95

Molecular determinants of allergen-induced effector cell degranulation. J Allergy Clin Immunol (2006) 0.94

Structural characterization of the tetrameric form of the major cat allergen Fel d 1. J Mol Biol (2007) 0.93

NMR study on the major mite allergen Der f 2: its refined tertiary structure, epitopes for monoclonal antibodies and characteristics shared by ML protein group members. J Biochem (2005) 0.93

Major mountain cedar allergen, Jun a 1, contains conformational as well as linear IgE epitopes. Mol Immunol (2006) 0.92

An in silico method using an epitope motif database for predicting the location of antigenic determinants on proteins in a structural context. J Mol Recognit (2005) 0.92

Roles of structure and structural dynamics in the antibody recognition of the allergen proteins: an NMR study on Blomia tropicalis major allergen. Structure (2008) 0.91

Identification of IgE-binding epitopes of the major peach allergen Pru p 3. J Allergy Clin Immunol (2003) 0.90

Detecting potential IgE-reactive sites on food proteins using a sequence and structure database, SDAP-food. J Agric Food Chem (2003) 0.90

Bla g 6: a troponin C allergen from Blattella germanica with IgE binding calcium dependence. J Allergy Clin Immunol (2006) 0.89

Calcium-binding allergens: from plants to man. Int Arch Allergy Immunol (1998) 0.88

Analysis of the structure and allergenicity of recombinant pro- and mature Der p 1 and Der f 1: major conformational IgE epitopes blocked by prodomains. J Allergy Clin Immunol (2005) 0.87

Nuclear magnetic resonance structure-based epitope mapping and modulation of dust mite group 13 allergen as a hypoallergen. J Immunol (2006) 0.87

Two major human allergenic sites on ragweed pollen allergen antigen E identified by using monoclonal antibodies. J Immunol (1986) 0.86

Gain of structure and IgE epitopes by eukaryotic expression of the major Timothy grass pollen allergen, Phl p 1. FEBS J (2005) 0.85

Discontinuous IgE-binding epitopes contain multiple continuous epitope regions: results of an epitope mapping on recombinant Hol l 5, a major allergen from velvet grass pollen. Clin Exp Allergy (2001) 0.84

Gastrointestinal digestion of Bet v 1-homologous food allergens destroys their mediator-releasing, but not T cell-activating, capacity. J Allergy Clin Immunol (2005) 0.83

Allergenicity and antigenicity of wild-type and mutant, monomeric, and dimeric carrot major allergen Dau c 1: destruction of conformation, not oligomerization, is the roadmap to save allergen vaccines. J Allergy Clin Immunol (2007) 0.83

Hydrogen exchange nuclear magnetic resonance spectroscopy mapping of antibody epitopes on the house dust mite allergen Der p 2. J Biol Chem (2000) 0.82

IgE-binding peptides coupled to a commercial matrix as a diagnostic instrument for persistent cow's milk allergy. J Allergy Clin Immunol (2005) 0.81

Absence of continuous epitopes in the house dust mite major allergens Der p I from Dermatophagoides pteronyssinus and Der f I from Dermatophagoides farinae. Clin Exp Allergy (1996) 0.80

Use of phage display technology to investigate allergen-antibody interactions. J Allergy Clin Immunol (2000) 0.78