The glucagon-like peptide 1 receptor is essential for postprandial lipoprotein synthesis and secretion in hamsters and mice.

PubWeight™: 1.58‹?› | Rank: Top 4%

🔗 View Article (PMID 19957161)

Published in Diabetologia on December 03, 2009

Authors

J Hsieh1, C Longuet, C L Baker, B Qin, L M Federico, D J Drucker, K Adeli

Author Affiliations

1: Department of Biochemistry, University of Toronto, Toronto, ON, Canada.

Articles citing this

Cardiovascular biology of the incretin system. Endocr Rev (2012) 2.42

Glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1: Incretin actions beyond the pancreas. J Diabetes Investig (2013) 1.55

DPP-4 inhibitors: impact on glycemic control and cardiovascular risk factors. Diabetes Care (2011) 1.39

Diet-induced adipose tissue inflammation and liver steatosis are prevented by DPP-4 inhibition in diabetic mice. Diabetes (2011) 1.37

The effect of glucagon-like peptide 1 on cardiovascular risk. Nat Rev Cardiol (2012) 1.32

Postprandial hyperlipidemia, endothelial dysfunction and cardiovascular risk: focus on incretins. Cardiovasc Diabetol (2011) 1.31

Cardiovascular effects of gliptins. Nat Rev Cardiol (2013) 1.23

Antidiabetic actions of endogenous and exogenous GLP-1 in type 1 diabetic patients with and without residual β-cell function. Diabetes (2011) 1.12

Intestinal DGAT1 deficiency reduces postprandial triglyceride and retinyl ester excursions by inhibiting chylomicron secretion and delaying gastric emptying. J Lipid Res (2012) 1.06

Pleiotropic effects of the dipeptidylpeptidase-4 inhibitors on the cardiovascular system. Am J Physiol Heart Circ Physiol (2014) 1.04

GLP-1 and GLP-2 as yin and yang of intestinal lipoprotein production: evidence for predominance of GLP-2-stimulated postprandial lipemia in normal and insulin-resistant states. Diabetes (2012) 1.03

Alogliptin ameliorates postprandial lipemia and postprandial endothelial dysfunction in non-diabetic subjects: a preliminary report. Cardiovasc Diabetol (2013) 0.99

Gut triglyceride production. Biochim Biophys Acta (2011) 0.97

Predictive Factors for Efficacy of Dipeptidyl Peptidase-4 Inhibitors in Patients with Type 2 Diabetes Mellitus. Diabetes Metab J (2015) 0.97

GLP-1 receptor activation inhibits VLDL production and reverses hepatic steatosis by decreasing hepatic lipogenesis in high-fat-fed APOE*3-Leiden mice. PLoS One (2012) 0.95

Glucagon-like peptide-1 receptor is present in pancreatic acinar cells and regulates amylase secretion through cAMP. Am J Physiol Gastrointest Liver Physiol (2015) 0.89

Teneligliptin: a DPP-4 inhibitor for the treatment of type 2 diabetes. Diabetes Metab Syndr Obes (2013) 0.88

Effect of sitagliptin on lipid profile in patients with type 2 diabetes mellitus. J Clin Med Res (2014) 0.88

Incretin hormones as immunomodulators of atherosclerosis. Front Endocrinol (Lausanne) (2012) 0.86

Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss. Int J Obes (Lond) (2014) 0.85

Sitagliptin, a DPP-4 inhibitor, acutely inhibits intestinal lipoprotein particle secretion in healthy humans. Diabetes (2014) 0.83

Clinical applications of advanced lipoprotein testing in diabetes mellitus. Clin Lipidol (2011) 0.80

Glucagon-like peptide-1 secretion by direct stimulation of L cells with luminal sugar vs non-nutritive sweetener. J Diabetes Investig (2012) 0.80

A 16-week study to compare the effect of vildagliptin versus gliclazide on postprandial lipoprotein concentrations and oxidative stress in patients with type 2 diabetes inadequately controlled with metformin monotherapy. Diabetol Metab Syndr (2015) 0.79

Recent Advances in Dipeptidyl-Peptidase-4 Inhibition Therapy: Lessons from the Bench and Clinical Trials. J Diabetes Res (2015) 0.79

The nonglycemic actions of dipeptidyl peptidase-4 inhibitors. Biomed Res Int (2014) 0.79

Postprandial Metabolism of Macronutrients and Cardiometabolic Risk: Recent Developments, Emerging Concepts, and Future Directions. Adv Nutr (2016) 0.78

The dipeptidyl peptidase-4 inhibitor sitagliptin protects against dyslipidemia-related kidney injury in Apolipoprotein E knockout mice. Int J Mol Sci (2014) 0.78

Effects of exenatide on postprandial vascular endothelial dysfunction in type 2 diabetes mellitus. Cardiovasc Diabetol (2015) 0.78

Glucagon-like peptide-2 regulates release of chylomicrons from the intestine. Gastroenterology (2014) 0.78

Pathophysiological mechanisms involved in non-alcoholic steatohepatitis and novel potential therapeutic targets. World J Hepatol (2015) 0.77

Single administration of vildagliptin attenuates postprandial hypertriglyceridemia and endothelial dysfunction in normoglycemic individuals. Exp Ther Med (2014) 0.77

Novel insights into the regulation of postprandial lipemia by glucagon-like peptides: significance for diabetes. Diabetes (2013) 0.77

GLP-1 receptor agonism ameliorates hepatic VLDL overproduction and de novo lipogenesis in insulin resistance. Mol Metab (2014) 0.77

Lipoprotein effects of incretin analogs and dipeptidyl peptidase 4 inhibitors. Clin Lipidol (2015) 0.77

The pathophysiology of intestinal lipoprotein production. Front Physiol (2015) 0.77

Minor Contribution of Endogenous GLP-1 and GLP-2 to Postprandial Lipemia in Obese Men. PLoS One (2016) 0.76

Comparison of sitagliptin with nateglinide on postprandial glucose and related hormones in drug-naïve Japanese patients with type 2 diabetes mellitus: A pilot study. J Diabetes Investig (2015) 0.75

Letter: The Effect of DPP-4 Inhibitors on Metabolic Parameters in Patients with Type 2 Diabetes (Diabetes Metab J 2014;38:211-9). Diabetes Metab J (2014) 0.75

Postprandial Hyperlipidemia and Remnant Lipoproteins. J Atheroscler Thromb (2016) 0.75

Essay for the 2011 CIHR/CMAJ award: glucagon-like peptides for metabolic and gastrointestinal disorders. CMAJ (2012) 0.75

Response: The Effect of DPP-4 Inhibitors on Metabolic Parameters in Patients with Type 2 Diabetes (Diabetes Metab J 2014;38:211-9). Diabetes Metab J (2014) 0.75

Comparison between sitagliptin and nateglinide on postprandial lipid levels: The STANDARD study. World J Diabetes (2013) 0.75

Articles by these authors

(truncated to the top 100)

Recombinant human DNase I reduces the viscosity of cystic fibrosis sputum. Proc Natl Acad Sci U S A (1990) 2.99

Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene. Nat Med (1996) 2.94

Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line. Proc Natl Acad Sci U S A (1987) 2.79

Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system. Endocrinology (2004) 2.65

Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas. Diabetes (2000) 2.50

Metformin regulates the incretin receptor axis via a pathway dependent on peroxisome proliferator-activated receptor-α in mice. Diabetologia (2010) 2.40

Chemical characterization of leptin-activated neurons in the rat brain. J Comp Neurol (2000) 2.21

Predicting cardiac complications in patients undergoing non-cardiac surgery. J Gen Intern Med (1986) 2.13

A new anatomical landmark for reliable identification of human area V5/MT: a quantitative analysis of sulcal patterning. Cereb Cortex (2000) 2.03

Enhanced insulin secretion and improved glucose tolerance in mice lacking CD26. Proc Natl Acad Sci U S A (2000) 1.91

Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivo. Genes Dev (1999) 1.86

Secretion of the intestinotropic hormone glucagon-like peptide 2 is differentially regulated by nutrients in humans. Gastroenterology (1999) 1.79

A cortical locus for the processing of contrast-defined contours. Nat Neurosci (1998) 1.77

Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors. Diabetes (2004) 1.68

Neuroendocrine function and response to stress in mice with complete disruption of glucagon-like peptide-1 receptor signaling. Endocrinology (2000) 1.63

Cost effectiveness of anterior cruciate ligament reconstruction in young adults. Clin Orthop Relat Res (1999) 1.49

Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model. J Biol Chem (2000) 1.46

Intestinal growth-promoting properties of glucagon-like peptide-2 in mice. Am J Physiol (1997) 1.43

Influence of fasting and sample collection time on 38 biochemical markers in healthy children: a CALIPER substudy. Clin Biochem (2012) 1.42

Human pattern-evoked electroretinogram. J Neurophysiol (1984) 1.41

Comments on Olympic Sports medicine. The Modern Pentathlon. Am J Sports Med (1983) 1.41

Effects of aging and a high fat diet on body weight and glucose tolerance in glucagon-like peptide-1 receptor -/- mice. Endocrinology (1998) 1.40

[Plasmodium falciparum malaria: type R1 resistance to quinine in west Africa]. Presse Med (1998) 1.38

Clinical laboratory investigation of the Sanofi ACCESS CK-MB procedure and comparison to electrophoresis and Abbott IMx. Am J Clin Pathol (1996) 1.37

The incidence of Hill-Sachs lesions in initial anterior shoulder dislocations. Arthroscopy (1989) 1.37

Alpha-cell-specific expression of the glucagon gene is conferred to the glucagon promoter element by the interactions of DNA-binding proteins. Mol Cell Biol (1988) 1.35

The LIM domain homeobox gene isl-1 is a positive regulator of islet cell-specific proglucagon gene transcription. J Biol Chem (1995) 1.32

Enteroendocrine localization of GLP-2 receptor expression in humans and rodents. Gastroenterology (2000) 1.31

Divergent tissue-specific and developmental expression of receptors for glucagon and glucagon-like peptide-1 in the mouse. Endocrinology (1994) 1.30

Tocotrienol: a review of its therapeutic potential. Clin Biochem (1999) 1.28

Enhanced glucose-dependent insulinotropic polypeptide secretion and insulinotropic action in glucagon-like peptide 1 receptor -/- mice. Diabetes (1998) 1.28

Glucagon-like peptide-1 receptor signalling selectively regulates murine lymphocyte proliferation and maintenance of peripheral regulatory T cells. Diabetologia (2010) 1.28

Regulation of glucagon-like peptide-1 synthesis and secretion in the GLUTag enteroendocrine cell line. Endocrinology (1998) 1.24

Chinese NiTi wire--a new orthodontic alloy. Am J Orthod (1985) 1.24

Characterization and functional role of voltage gated cation conductances in the glucagon-like peptide-1 secreting GLUTag cell line. J Physiol (2004) 1.23

The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization. Nat Struct Biol (2001) 1.23

Prototypic G protein-coupled receptor for the intestinotrophic factor glucagon-like peptide 2. Proc Natl Acad Sci U S A (1999) 1.22

Glucagon and glucagon-like peptide receptors as drug targets. Curr Pharm Des (2006) 1.21

Intestinal function in mice with small bowel growth induced by glucagon-like peptide-2. Am J Physiol (1997) 1.20

A circadian clock in Neurospora: how genes and proteins cooperate to produce a sustained, entrainable, and compensated biological oscillator with a period of about a day. Cold Spring Harb Symp Quant Biol (2007) 1.19

Operative ankle arthroscopy. Long-term followup. Am J Sports Med (1989) 1.18

Spatiotemporal patterns and ecophysiology of toxigenic microcystis blooms in Lake Taihu, China: implications for water quality management. Environ Sci Technol (2012) 1.16

The release of 40S hnRNP particles by brief digestion of HeLa nuclei with micrococcal nuclease. Nucleic Acids Res (1980) 1.16

Identification and characterization of a novel sucrose-non-fermenting protein kinase/AMP-activated protein kinase-related protein kinase, SNARK. Biochem J (2001) 1.13

Efavirenz-induced decrease in plasma amprenavir levels in human immunodeficiency virus-infected patients and correction by ritonavir. Antimicrob Agents Chemother (2000) 1.12

Activation of proglucagon gene transcription through a novel promoter element by the caudal-related homeodomain protein cdx-2/3. Mol Cell Biol (1996) 1.10

Structure-function of the glucagon receptor family of G protein-coupled receptors: the glucagon, GIP, GLP-1, and GLP-2 receptors. Receptors Channels (2002) 1.09

Comparison of lateral ankle ligamentous reconstruction procedures. Am J Sports Med (1994) 1.08

Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, regulates fasting glycemia and nonenteral glucose clearance in mice. Endocrinology (2000) 1.08

UVB radiation induces p21Cip1/WAF1 and mediates G1 and S phase checkpoints. Oncogene (1996) 1.07

Mouse pancreatic beta-cells exhibit preserved glucose competence after disruption of the glucagon-like peptide-1 receptor gene. Diabetes (1998) 1.06

Arthroscopically assisted rotator cuff repair: correlation of functional results with integrity of the cuff. Arthroscopy (1994) 1.06

Glucagon gene 5'-flanking sequences direct expression of simian virus 40 large T antigen to the intestine, producing carcinoma of the large bowel in transgenic mice. J Biol Chem (1992) 1.06

Identification of glucagon-like peptide 1 (GLP-1) actions essential for glucose homeostasis in mice with disruption of GLP-1 receptor signaling. Diabetes (1998) 1.05

Popliteal cyst: a surgical approach. Orthopedics (1991) 1.05

Apolipoprotein E polymorphism and serum concentration in Alzheimer's disease in nine European centres: the ApoEurope study. ApoEurope group. Clin Chem Lab Med (2000) 1.04

Proglucagon processing in a rat islet cell line resembles phenotype of intestine rather than pancreas. Endocrinology (1986) 1.04

Glucagon-like peptide (GLP)-2 action in the murine central nervous system is enhanced by elimination of GLP-1 receptor signaling. J Biol Chem (2001) 1.03

Free fatty acid-induced muscle insulin resistance and glucose uptake dysfunction: evidence for PKC activation and oxidative stress-activated signaling pathways. Biochem Biophys Res Commun (2009) 1.02

Immunocytochemical localization of parathyroid hormone-like peptide in the rat fetus. Cancer Res (1991) 1.02

Circulating and tissue forms of the intestinal growth factor, glucagon-like peptide-2. Endocrinology (1997) 1.00

Biological determinants of intestinotrophic properties of GLP-2 in vivo. Am J Physiol (1997) 1.00

Parathyroid hormone-related peptide expression in primary and metastatic liver tumours. Histopathology (1993) 0.99

Prevalence of negative-pressure pulmonary edema at an orthopaedic hospital. J South Orthop Assoc (2000) 0.99

The Cushing syndrome induced by medroxyprogesterone acetate. Ann Intern Med (1989) 0.98

Essential requirement for Pax6 in control of enteroendocrine proglucagon gene transcription. Mol Endocrinol (1999) 0.98

A processing stream in mammalian visual cortex neurons for non-Fourier responses. Science (1993) 0.98

Glucagon-like peptide 2 decreases mortality and reduces the severity of indomethacin-induced murine enteritis. Am J Physiol (1999) 0.98

Acute posterolateral rotatory instability of the knee. J Bone Joint Surg Am (1983) 0.97

The pattern evoked electroretinogram: its variability in normals and its relationship to amblyopia. Invest Ophthalmol Vis Sci (1985) 0.96

Glucagon-like peptide 1 receptor signaling influences topography of islet cells in mice. Virchows Arch (2001) 0.96

Altered cAMP and Ca2+ signaling in mouse pancreatic islets with glucagon-like peptide-1 receptor null phenotype. Diabetes (1999) 0.96

Cell-specific post-translational processing of preproglucagon expressed from a metallothionein-glucagon fusion gene. J Biol Chem (1986) 0.96

A sensitive and rapid mass spectrometric method for the simultaneous measurement of eight steroid hormones and CALIPER pediatric reference intervals. Clin Biochem (2013) 0.95

Tissue-specific expression of unique mRNAs that encode proglucagon-derived peptides or exendin 4 in the lizard. J Biol Chem (1997) 0.94

Islet cell and extrapancreatic expression of the LIM domain homeobox gene isl-1. Mol Endocrinol (1991) 0.94

Modulation of hepatic lipoprotein synthesis and secretion by taxifolin, a plant flavonoid. J Lipid Res (2000) 0.94

Assessment of retinal function in severely amblyopic individuals. Vision Res (1984) 0.93

Eccentricity-dependent scaling of the limits for short-range apparent motion perception. Vision Res (1985) 0.93

Parathyroid hormone-like peptide in normal and neoplastic human endocrine tissues. J Clin Endocrinol Metab (1990) 0.93

Circulating levels of glucagon-like peptide-2 in human subjects with inflammatory bowel disease. Am J Physiol Regul Integr Comp Physiol (2000) 0.93

Glucagon gene transcription in an islet cell line is regulated via a protein kinase C-activated pathway. J Biol Chem (1987) 0.93

Glucagon-like peptide (GLP)-2 reduces chemotherapy-associated mortality and enhances cell survival in cells expressing a transfected GLP-2 receptor. Cancer Res (2001) 0.93

Identification of glucagon-like peptide-2 (GLP-2)-activated signaling pathways in baby hamster kidney fibroblasts expressing the rat GLP-2 receptor. J Biol Chem (1999) 0.93

Temporal and spatial response to second-order stimuli in cat area 18. J Neurophysiol (1998) 0.93

Anterior cruciate ligament reconstruction: socioeconomic issues and cost effectiveness. Am J Orthop (Belle Mead NJ) (2000) 0.93

Suppression of spinal cord motoneuron excitability correlates with surgical immobility during isoflurane anesthesia. Anesthesiology (1998) 0.92

Genetic testing for feline polycystic kidney disease. Anim Genet (2004) 0.91

Homology among 3S and 7S Globulins from Cereals and Pea. Plant Physiol (1985) 0.91

Thyroid hormone modulates apolipoprotein B gene expression in HepG2 cells. Biochem Biophys Res Commun (1992) 0.90

UVB radiation-activated genes induced by transcriptional and posttranscriptional mechanisms in rat keratinocytes. Am J Physiol (1995) 0.90

The glucagon-like peptide-2 receptor mediates direct inhibition of cellular apoptosis via a cAMP-dependent protein kinase-independent pathway. J Biol Chem (2000) 0.90

Efficacy and tolerability of stavudine plus lamivudine in treatment-naive and treatment-experienced patients with HIV-1 infection. Ann Intern Med (1998) 0.90

Enzymatic- and renal-dependent catabolism of the intestinotropic hormone glucagon-like peptide-2 in rats. Am J Physiol Endocrinol Metab (2000) 0.89

Fish consumption and risk of stroke and its subtypes: accumulative evidence from a meta-analysis of prospective cohort studies. Eur J Clin Nutr (2012) 0.89

Purification and characterization of an extracellular thiol-containing serine proteinase from Thermomyces lanuginosus. Biochem Cell Biol (1992) 0.89

Linear and nonlinear components of human electroretinogram. J Neurophysiol (1984) 0.88

Conformational changes in apolipoprotein B modulate intracellular assembly and degradation of ApoB-containing lipoprotein particles in HepG2 cells. Arterioscler Thromb Vasc Biol (1997) 0.88

Motion perception over long interstimulus intervals. Percept Psychophys (1999) 0.87

Envelope-responsive neurons in areas 17 and 18 of cat. J Neurophysiol (1994) 0.87