Published in Can J Cardiol on December 01, 2009
Preventing deep wound infection after coronary artery bypass grafting: a review. Tex Heart Inst J (2013) 0.95
Temporal trends and practice variations in clopidogrel loading doses in patients with non-ST-segment elevation myocardial infarction, from the National Cardiovascular Data Registry. Am Heart J (2011) 0.81
Transfusion strategy: impact of haemodynamics and the challenge of haemodilution. J Blood Transfus (2014) 0.78
Pharmacotherapy in the cardiac catheterization laboratory: evolution and recent developments. Ther Clin Risk Manag (2014) 0.75
Should dual antiplatelet therapy be used in patients following coronary artery bypass surgery? A meta-analysis of randomized controlled trials. BMC Surg (2015) 0.75
Surgical tracheotomy performed with and without dual antiplatelet therapy. Open Med (Wars) (2014) 0.75
Clopidogrel use After Myocardial Revascularization: Prevalence, Predictors, and One-Year Survival Rate. Braz J Cardiovasc Surg (2016) 0.75
Management and Prevention of Saphenous Vein Graft Failure: A Review. Cardiol Ther (2017) 0.75
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med (2001) 20.20
Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med (2009) 18.03
Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med (2007) 17.85
Effect of clopidogrel added to aspirin in patients with atrial fibrillation. N Engl J Med (2009) 11.49
Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial. JAMA (2002) 11.06
Duration of red-cell storage and complications after cardiac surgery. N Engl J Med (2008) 10.04
Comparison of early invasive and conservative strategies in patients with unstable coronary syndromes treated with the glycoprotein IIb/IIIa inhibitor tirofiban. N Engl J Med (2001) 9.31
Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study. Lancet (2001) 8.54
Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome. JAMA (2009) 7.78
Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes. Eur Heart J (2007) 6.51
Protective effects of aspirin against acute myocardial infarction and death in men with unstable angina. Results of a Veterans Administration Cooperative Study. N Engl J Med (1983) 6.00
Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial. Lancet (2005) 5.86
Perioperative blood transfusion and blood conservation in cardiac surgery: the Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists clinical practice guideline. Ann Thorac Surg (2007) 5.32
Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery. Circulation (2007) 5.31
Morbidity and mortality risk associated with red blood cell and blood-component transfusion in isolated coronary artery bypass grafting. Crit Care Med (2006) 4.59
Guideline on antiplatelet and anticoagulation management in cardiac surgery. Eur J Cardiothorac Surg (2008) 4.36
Aspirin, sulfinpyrazone, or both in unstable angina. Results of a Canadian multicenter trial. N Engl J Med (1985) 2.99
The effect of clopidogrel in combination with aspirin when given before coronary artery bypass grafting. J Am Coll Cardiol (2002) 2.98
Low hematocrit during cardiopulmonary bypass is associated with increased risk of perioperative stroke in cardiac surgery. Ann Thorac Surg (2005) 2.91
Association of laboratory-defined aspirin resistance with a higher risk of recurrent cardiovascular events: a systematic review and meta-analysis. Arch Intern Med (2007) 2.88
Impact of preoperative anemia on outcome in patients undergoing coronary artery bypass graft surgery. Circulation (2007) 2.49
Transfusion in coronary artery bypass grafting is associated with reduced long-term survival. Ann Thorac Surg (2006) 2.42
Impact of platelet reactivity on cardiovascular outcomes in patients with type 2 diabetes mellitus and coronary artery disease. J Am Coll Cardiol (2007) 1.94
Hemodilution during cardiopulmonary bypass is an independent risk factor for acute renal failure in adult cardiac surgery. J Thorac Cardiovasc Surg (2005) 1.93
Persistent effect of red cell transfusion on health-related quality of life after cardiac surgery. Ann Thorac Surg (2006) 1.80
Effect of atorvastatin on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in healthy subjects. Pharmacotherapy (2008) 1.77
High clopidogrel loading dose during coronary stenting: effects on drug response and interindividual variability. Eur Heart J (2004) 1.77
Reexploration for bleeding is a risk factor for adverse outcomes after cardiac operations. J Thorac Cardiovasc Surg (1996) 1.73
Red cell transfusion is associated with an increased risk for postoperative atrial fibrillation. Ann Thorac Surg (2006) 1.71
Outcomes following pre-operative clopidogrel administration in patients with acute coronary syndromes undergoing coronary artery bypass surgery: the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial. J Am Coll Cardiol (2009) 1.70
Acute clopidogrel use and outcomes in patients with non-ST-segment elevation acute coronary syndromes undergoing coronary artery bypass surgery. J Am Coll Cardiol (2006) 1.67
Impact of clopidogrel in patients with acute coronary syndromes requiring coronary artery bypass surgery: a multicenter analysis. J Am Coll Cardiol (2008) 1.62
Resternotomy for bleeding after cardiac operation: a marker for increased morbidity and mortality. Ann Thorac Surg (1995) 1.58
Acute coronary syndromes in the GUSTO-IIb trial: prognostic insights and impact of recurrent ischemia. The GUSTO-IIb Investigators. Circulation (1998) 1.52
Is CURE a cure for acute coronary syndromes? Statistical versus clinical significance. J Am Coll Cardiol (2002) 1.50
Aspirin-resistant platelet aggregation in a cohort of patients with coronary heart disease. Blood Coagul Fibrinolysis (2007) 1.42
Effect of clopidogrel on bleeding after coronary artery bypass surgery. Crit Care Med (2001) 1.34
Risk associated with preoperative anemia in cardiac surgery: a multicenter cohort study. Circulation (2008) 1.27
Clopidogrel withdrawal is associated with proinflammatory and prothrombotic effects in patients with diabetes and coronary artery disease. Diabetes (2006) 1.27
Effects of megakaryocyte growth and development factor on platelet production, platelet life span, and platelet function in healthy human volunteers. Blood (2000) 1.26
Transfusion increases the risk of postoperative infection after cardiovascular surgery. J Am Coll Surg (2005) 1.21
A randomized comparison of high clopidogrel loading doses in patients with non-ST-segment elevation acute coronary syndromes: the ALBION (Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) trial. J Am Coll Cardiol (2006) 1.15
Clopidogrel and bleeding in patients undergoing elective coronary artery bypass grafting. J Thorac Cardiovasc Surg (2004) 1.01
Rapidity and duration of platelet suppression by enteric-coated aspirin in healthy young men. Am J Cardiol (1992) 1.01
Clopidogrel-associated bleeding and related complications in patients undergoing coronary artery bypass grafting. Pharmacotherapy (2008) 0.90
A risk score to estimate the likelihood of coronary artery bypass surgery during the index hospitalization among patients with unstable angina and non-ST-segment elevation myocardial infarction. J Am Coll Cardiol (2004) 0.88
Immediate coronary artery bypass surgery after platelet inhibition with eptifibatide: results from PURSUIT. Platelet Glycoprotein IIb/IIIa in Unstable Angina: Receptor Suppression Using Integrelin Therapy. Ann Thorac Surg (2000) 0.86
Early cardiac catheterization is associated with lower mortality only among high-risk patients with ST- and non-ST-elevation acute coronary syndromes: observations from the OPUS-TIMI 16 trial. Am Heart J (2005) 0.85
Early administration of clopidogrel is safe after off-pump coronary artery bypass surgery. Ann Thorac Surg (2006) 0.84
Does clopidogrel affect outcome after coronary artery bypass grafting? A meta-analysis. Heart (2006) 0.83
Clopidogrel and bleeding after coronary artery bypass graft surgery. Ann Thorac Surg (2005) 0.83
The Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE) study: to what extent should the results be generalizable? Am Heart J (2003) 0.82
Clopidogrel use and bleeding after coronary artery bypass graft surgery. Am Heart J (2008) 0.82
Clinical implications of percutaneous coronary intervention-clopidogrel in unstable angina to prevent recurrent events (PCI-CURE) study: a US perspective. Circulation (2002) 0.81
Temporal trends and patterns of early clopidogrel use across the spectrum of acute coronary syndromes. Am Heart J (2009) 0.81
The additive antiplatelet action of clopidogrel in patients with coronary artery disease treated with aspirin. Thromb Haemost (2007) 0.80
Clopidogrel plus aspirin for stroke prevention. Stroke (2002) 0.79
Benefits and risks of clopidogrel pretreatment before coronary artery bypass grafting in patients with ST-elevation myocardial infarction treated with fibrinolytics in CLARITY-TIMI 28. J Thromb Thrombolysis (2007) 0.78
Aprotinin reduces bleeding and blood product use in patients treated with clopidogrel before coronary artery bypass grafting. Ann Thorac Surg (2005) 0.77
Preoperative use of enoxaparin increases the risk of postoperative bleeding and re-exploration in cardiac surgery patients. J Cardiothorac Vasc Anesth (2005) 0.76
Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med (2009) 39.97
Apixaban in patients with atrial fibrillation. N Engl J Med (2011) 9.97
Standardized bleeding definitions for cardiovascular clinical trials: a consensus report from the Bleeding Academic Research Consortium. Circulation (2011) 6.36
Aspirin in patients undergoing noncardiac surgery. N Engl J Med (2014) 6.10
2012 update of the Canadian Cardiovascular Society guidelines for the diagnosis and treatment of dyslipidemia for the prevention of cardiovascular disease in the adult. Can J Cardiol (2013) 5.97
Idarucizumab for Dabigatran Reversal. N Engl J Med (2015) 5.91
2009 Canadian Cardiovascular Society/Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult - 2009 recommendations. Can J Cardiol (2009) 5.65
A comparison of aprotinin and lysine analogues in high-risk cardiac surgery. N Engl J Med (2008) 5.20
Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines. J Clin Invest (2006) 4.51
Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: results from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) randomized trial. Circulation (2012) 4.33
Clinical and pathophysiological implications of a bicuspid aortic valve. Circulation (2002) 3.98
Oral anticoagulant and antiplatelet therapy and peripheral arterial disease. N Engl J Med (2007) 3.74
Non-ATG-initiated translation directed by microsatellite expansions. Proc Natl Acad Sci U S A (2010) 3.58
A propensity score case-control comparison of aprotinin and tranexamic acid in high-transfusion-risk cardiac surgery. Transfusion (2006) 3.56
Adipokines: molecular links between obesity and atheroslcerosis. Am J Physiol Heart Circ Physiol (2005) 3.15
Acute kidney injury after cardiac surgery: focus on modifiable risk factors. Circulation (2009) 3.10
Radial artery grafts vs saphenous vein grafts in coronary artery bypass surgery: a randomized trial. JAMA (2011) 3.03
Activation of translation complex eIF4F is essential for the genesis and maintenance of the malignant phenotype in human mammary epithelial cells. Cancer Cell (2004) 2.91
Derivation and validation of a simplified predictive index for renal replacement therapy after cardiac surgery. JAMA (2007) 2.89
Effect of aspirin on mortality in the primary prevention of cardiovascular disease. Am J Med (2011) 2.65
The Long-Term Multicenter Observational Study of Dabigatran Treatment in Patients With Atrial Fibrillation (RELY-ABLE) Study. Circulation (2013) 2.64
Causes of death and influencing factors in patients with atrial fibrillation: a competing-risk analysis from the randomized evaluation of long-term anticoagulant therapy study. Circulation (2013) 2.48
Thoracic complications of nasogastric tube: review of safe practice. Interact Cardiovasc Thorac Surg (2005) 2.48
Risks for stroke, bleeding, and death in patients with atrial fibrillation receiving dabigatran or warfarin in relation to the CHADS2 score: a subgroup analysis of the RE-LY trial. Ann Intern Med (2011) 2.45
New markers of inflammation and endothelial cell activation: Part I. Circulation (2003) 2.43
Advance targeted transfusion in anemic cardiac surgical patients for kidney protection: an unblinded randomized pilot clinical trial. Anesthesiology (2012) 2.29
Predicting deep venous thrombosis in pregnancy: out in "LEFt" field? Ann Intern Med (2009) 2.26
Hyperglycemia during cardiopulmonary bypass is an independent risk factor for mortality in patients undergoing cardiac surgery. J Thorac Cardiovasc Surg (2005) 2.24
C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscle. Circulation (2003) 2.16
Xenotransplant cardiac chimera: immune tolerance of adult stem cells. Ann Thorac Surg (2002) 2.10
The independent association of massive blood loss with mortality in cardiac surgery. Transfusion (2004) 2.09
Clonidine in patients undergoing noncardiac surgery. N Engl J Med (2014) 2.07
Perioperative blood conservation--the experts, the elephants, the clinicians, and the gauntlet. Can J Anaesth (2007) 2.04
Calcium antagonists are associated with reduced mortality after cardiac surgery: a propensity analysis. J Thorac Cardiovasc Surg (2004) 2.03
Angiotensin receptor blockers and myocardial infarction. BMJ (2004) 2.02
Processed residual pump blood in cardiac surgery: the Processed Residual Blood in Cardiac surgery trial. Transfusion (2012) 2.02
Microplegia during coronary artery bypass grafting was associated with less low cardiac output syndrome: a propensity-matched comparison. Ann Thorac Surg (2013) 2.00
Hyperchloremia after noncardiac surgery is independently associated with increased morbidity and mortality: a propensity-matched cohort study. Anesth Analg (2013) 1.99
Vascular matrix remodeling in patients with bicuspid aortic valve malformations: implications for aortic dilatation. J Thorac Cardiovasc Surg (2003) 1.96
Endothelial progenitor cells: new hope for a broken heart. Circulation (2003) 1.93
Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis. J Exp Med (2008) 1.93
Myocardial ischemic events in patients with atrial fibrillation treated with dabigatran or warfarin in the RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) trial. Circulation (2012) 1.83
Effects of cardiac resynchronization therapy with or without a defibrillator on survival and hospitalizations in patients with New York Heart Association class IV heart failure. Circulation (2006) 1.81
Adiponectin deficiency promotes endothelial activation and profoundly exacerbates sepsis-related mortality. Am J Physiol Endocrinol Metab (2008) 1.79
Apixaban versus aspirin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a predefined subgroup analysis from AVERROES, a randomised trial. Lancet Neurol (2012) 1.76
South Asians and cardiovascular risk: what clinicians should know. Circulation (2006) 1.74
Development and validation of Transfusion Risk Understanding Scoring Tool (TRUST) to stratify cardiac surgery patients according to their blood transfusion needs. Transfusion (2006) 1.72
Characterization of clopidogrel hypersensitivity reactions and management with oral steroids without clopidogrel discontinuation. J Am Coll Cardiol (2011) 1.72
Enalapril increases ischemia-induced endothelial progenitor cell mobilization through manipulation of the CD26 system. J Mol Cell Cardiol (2006) 1.69
Does tight heart rate control improve beta-blocker efficacy? An updated analysis of the noncardiac surgical randomized trials. Anesth Analg (2008) 1.65
C-reactive protein upregulates complement-inhibitory factors in endothelial cells. Circulation (2004) 1.65
Hyperosmotic stress activates Rho: differential involvement in Rho kinase-dependent MLC phosphorylation and NKCC activation. Am J Physiol Cell Physiol (2003) 1.64
Use of antifibrinolytic therapy to reduce transfusion in patients undergoing orthopedic surgery: a systematic review of randomized trials. Thromb Res (2008) 1.64
Rationale and design of the Cardiovascular Inflammation Reduction Trial: a test of the inflammatory hypothesis of atherothrombosis. Am Heart J (2013) 1.60
Plasma renin activity predicts cardiovascular mortality in the Heart Outcomes Prevention Evaluation (HOPE) study. Eur Heart J (2011) 1.59
Microvascular function predicts cardiovascular events in primary prevention: long-term results from the Firefighters and Their Endothelium (FATE) study. Circulation (2011) 1.58
A randomized trial of diagnostic strategies after normal proximal vein ultrasonography for suspected deep venous thrombosis: D-dimer testing compared with repeated ultrasonography. Ann Intern Med (2005) 1.57
Perceptions of Canadian primary care physicians towards cardiovascular risk assessment and lipid management. Can J Cardiol (2012) 1.56
Fibrotic extracellular matrix activates a profibrotic positive feedback loop. J Clin Invest (2014) 1.54
The clinical utility of an index of global oxygenation for guiding red blood cell transfusion in cardiac surgery. Transfusion (2009) 1.54
Focused 2012 update of the Canadian Cardiovascular Society guidelines for the use of antiplatelet therapy. Can J Cardiol (2013) 1.54
Glitazones and heart failure: critical appraisal for the clinician. Circulation (2003) 1.53
A red blood cell agglutination D-dimer test to exclude deep venous thrombosis in pregnancy. Ann Intern Med (2007) 1.53
Canadian Cardiovascular Society Consensus Conference: peripheral arterial disease - executive summary. Can J Cardiol (2005) 1.53
Relationship between carotid artery intima-media thickness and brachial artery flow-mediated dilation in middle-aged healthy men. J Am Coll Cardiol (2005) 1.53
Predictors of low cardiac output syndrome after isolated coronary artery bypass surgery: trends over 20 years. Ann Thorac Surg (2011) 1.52
Challenges of establishing new antithrombotic therapies in atrial fibrillation. Circulation (2007) 1.52
N-acetylcysteine is associated with increased blood loss and blood product utilization during cardiac surgery. Crit Care Med (2009) 1.51
Effects of cell-based angiogenic gene therapy at 6 months: persistent angiogenesis and absence of oncogenicity. Ann Thorac Surg (2007) 1.50
New developments in the treatment of hypoplastic left heart syndrome. Pediatrics (2007) 1.49
Fundamentals of reperfusion injury for the clinical cardiologist. Circulation (2002) 1.49
Off-pump coronary artery surgery for reducing mortality and morbidity: meta-analysis of randomized and observational studies. J Am Coll Cardiol (2005) 1.49
Myocardial injury after noncardiac surgery: a large, international, prospective cohort study establishing diagnostic criteria, characteristics, predictors, and 30-day outcomes. Anesthesiology (2014) 1.47
The short-term and long-term effects of warm or tepid cardioplegia. J Thorac Cardiovasc Surg (2003) 1.46
The role of recombinant factor VIIa in on-pump cardiac surgery: proceedings of the Canadian Consensus Conference. Can J Anaesth (2007) 1.46
Mechanical stretch regimen enhances the formation of bioengineered autologous cardiac muscle grafts. Circulation (2002) 1.45
Beta-blockade mitigates exercise blood pressure in hypertensive male patients. J Am Coll Cardiol (2006) 1.45
Acute surgical anemia influences the cardioprotective effects of beta-blockade: a single-center, propensity-matched cohort study. Anesthesiology (2010) 1.44
Direct thrombin inhibitors in acute coronary syndromes: effect in patients undergoing early percutaneous coronary intervention. Eur Heart J (2005) 1.42
Aged human cells rejuvenated by cytokine enhancement of biomaterials for surgical ventricular restoration. J Am Coll Cardiol (2012) 1.42
Suboptimal use of statin therapy in elderly patients with atherosclerosis: a population-based study. J Vasc Surg (2008) 1.42
The post-BART anti-fibrinolytic dilemma? J Cardiothorac Vasc Anesth (2011) 1.42
Translational control of cell fate: availability of phosphorylation sites on translational repressor 4E-BP1 governs its proapoptotic potency. Mol Cell Biol (2002) 1.42
Transmyocardial revascularization induces mesenchymal stem cell engraftment in infarcted hearts. Ann Thorac Surg (2012) 1.41
Comparative efficacy and safety of anticoagulant strategies for acute coronary syndromes. Comprehensive network meta-analysis of 42 randomised trials involving 117,353 patients. Thromb Haemost (2015) 1.40
Practice nurses and clinical autonomy. Nurs N Z (2007) 1.40
Characterization of operator learning curve for transradial coronary interventions. Circ Cardiovasc Interv (2011) 1.40
MicroRNA-145 targeted therapy reduces atherosclerosis. Circulation (2012) 1.39
Risk associated with preoperative anemia in noncardiac surgery: a single-center cohort study. Anesthesiology (2009) 1.39
A 10-year comparison of explanted Hancock-II and Carpentier-Edwards supraannular bioprostheses. Cardiovasc Pathol (2007) 1.39
Can we develop a Canadian Perioperative Anesthesiology Clinical Trials group? Can J Anaesth (2010) 1.38
Mitral repair versus replacement for ischemic mitral regurgitation. Ann Thorac Surg (2005) 1.36
Design and rationale for RE-VERSE AD: A phase 3 study of idarucizumab, a specific reversal agent for dabigatran. Thromb Haemost (2015) 1.36
TIMP-3 deficiency leads to dilated cardiomyopathy. Circulation (2004) 1.36
Adiponectin primes human monocytes into alternative anti-inflammatory M2 macrophages. Am J Physiol Heart Circ Physiol (2010) 1.34