PubRank

W Conrad Liles

Author PubWeight™ 130.72‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist. J Exp Med 2005 7.01
2 Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis. Am J Respir Crit Care Med 2010 3.83
3 Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1. PLoS Med 2007 3.64
4 Use of peroxisome proliferator-activated receptor gamma agonists as adjunctive treatment for Plasmodium falciparum malaria: a randomized, double-blind, placebo-controlled trial. Clin Infect Dis 2009 2.66
5 Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis. Crit Care Med 2011 2.59
6 Cellular and molecular abnormalities in severe congenital neutropenia predisposing to leukemia. Exp Hematol 2003 2.25
7 The phagocytes: neutrophils and monocytes. Blood 2008 2.25
8 Modulation of lipopolysaccharide-induced gene transcription and promotion of lung injury by mechanical ventilation. J Immunol 2005 2.05
9 Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children. PLoS One 2009 1.93
10 Granulocyte transfusion therapy for infections in candidates and recipients of HPC transplantation: a comparative analysis of feasibility and outcome for community donors versus related donors. Transfusion 2002 1.89
11 Mechanical ventilation induces inflammation, lung injury, and extra-pulmonary organ dysfunction in experimental pneumonia. Lab Invest 2006 1.60
12 Whole blood angiopoietin-1 and -2 levels discriminate cerebral and severe (non-cerebral) malaria from uncomplicated malaria. Malar J 2009 1.59
13 Fas (CD95) induces proinflammatory cytokine responses by human monocytes and monocyte-derived macrophages. J Immunol 2003 1.57
14 Combinations of host biomarkers predict mortality among Ugandan children with severe malaria: a retrospective case-control study. PLoS One 2011 1.55
15 Biomarkers of endothelial activation/dysfunction in infectious diseases. Virulence 2013 1.42
16 C5 deficiency and C5a or C5aR blockade protects against cerebral malaria. J Exp Med 2008 1.38
17 Optimal timing to repopulation of resident alveolar macrophages with donor cells following total body irradiation and bone marrow transplantation in mice. J Immunol Methods 2004 1.32
18 Parasite burden and CD36-mediated sequestration are determinants of acute lung injury in an experimental malaria model. PLoS Pathog 2008 1.28
19 Differential response of human lung epithelial cells to fas-induced apoptosis. Am J Pathol 2004 1.27
20 Mechanical ventilation interacts with endotoxemia to induce extrapulmonary organ dysfunction. Crit Care 2006 1.25
21 Differential constitutive and cytokine-modulated expression of human Toll-like receptors in primary neutrophils, monocytes, and macrophages. Int J Med Sci 2008 1.24
22 Physiological functions of caspases beyond cell death. Am J Pathol 2006 1.22
23 Fas-mediated acute lung injury requires fas expression on nonmyeloid cells of the lung. J Immunol 2005 1.22
24 Simultaneous host and parasite expression profiling identifies tissue-specific transcriptional programs associated with susceptibility or resistance to experimental cerebral malaria. BMC Genomics 2006 1.20
25 Expression microarray analysis implicates apoptosis and interferon-responsive mechanisms in susceptibility to experimental cerebral malaria. Am J Pathol 2007 1.20
26 The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin-associated hemolytic uremic syndrome in humans and mice. J Clin Invest 2012 1.18
27 Leukocytosis and Mobilization of CD34+ Hematopoietic Progenitor Cells by AMD3100, a CXCR4 Antagonist. Support Cancer Ther 2004 1.16
28 C5a enhances dysregulated inflammatory and angiogenic responses to malaria in vitro: potential implications for placental malaria. PLoS One 2009 1.16
29 Computational identification of key biological modules and transcription factors in acute lung injury. Am J Respir Crit Care Med 2005 1.15
30 Therapeutic use of cytokines to modulate phagocyte function for the treatment of infectious diseases: current status of granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, macrophage colony-stimulating factor, and interferon-gamma. J Infect Dis 2002 1.13
31 Apoptosis of vascular smooth muscle cells is induced by Fas ligand derived from monocytes/macrophage. Atherosclerosis 2002 1.12
32 Differential role of MyD88 in macrophage-mediated responses to opportunistic fungal pathogens. Infect Immun 2003 1.11
33 Endothelial activation, dysfunction and permeability during severe infections. Curr Opin Hematol 2011 1.11
34 Sustained lipopolysaccharide-induced lung inflammation in mice is attenuated by functional deficiency of the Fas/Fas ligand system. Clin Diagn Lab Immunol 2004 1.08
35 Pandemic H1N1 influenza infection and vascular thrombosis. Clin Infect Dis 2011 1.08
36 Use of a three-band HRP2/pLDH combination rapid diagnostic test increases diagnostic specificity for falciparum malaria in Ugandan children. Malar J 2014 1.07
37 Blockade of the Fas/FasL system improves pneumococcal clearance from the lungs without preventing dissemination of bacteria to the spleen. J Infect Dis 2005 1.06
38 Fas (CD95) induces macrophage proinflammatory chemokine production via a MyD88-dependent, caspase-independent pathway. J Leukoc Biol 2007 1.06
39 Mycobacterium tuberculosis bacteremia in a cohort of hiv-infected patients hospitalized with severe sepsis in uganda–high frequency, low clinical suspicion [corrected] and derivation of a clinical prediction score. PLoS One 2013 1.06
40 PSGL-1 and mTOR regulate translation of ROCK-1 and physiological functions of macrophages. EMBO J 2007 1.06
41 Inhaled nitric oxide for the adjunctive therapy of severe malaria: protocol for a randomized controlled trial. Trials 2011 1.06
42 Gemcitabine-related "pseudocellulitis": report of 2 cases and review of the literature. Clin Infect Dis 2007 1.05
43 Immunopathogenesis of falciparum malaria: implications for adjunctive therapy in the management of severe and cerebral malaria. Expert Rev Anti Infect Ther 2011 1.05
44 NADPH oxidase restrains the matrix metalloproteinase activity of macrophages. J Biol Chem 2005 1.04
45 Clinical utility of biomarkers of endothelial activation in sepsis--a systematic review. Crit Care 2012 1.04
46 Inhaled nitric oxide reduces endothelial activation and parasite accumulation in the brain, and enhances survival in experimental cerebral malaria. PLoS One 2011 1.03
47 Rosiglitazone modulates the innate immune response to Plasmodium falciparum infection and improves outcome in experimental cerebral malaria. J Infect Dis 2009 1.03
48 S1P is associated with protection in human and experimental cerebral malaria. Mol Med 2011 1.02
49 Emerging therapeutic strategies to prevent infection-related microvascular endothelial activation and dysfunction. Virulence 2013 1.02
50 cDNA microarray analysis reveals fundamental differences in the expression profiles of primary human monocytes, monocyte-derived macrophages, and alveolar macrophages. J Leukoc Biol 2006 1.02
51 Immunomodulatory therapy for severe influenza. Expert Rev Anti Infect Ther 2011 1.01
52 Malaria exacerbates experimental mycobacterial infection in vitro and in vivo. Microbes Infect 2010 0.99
53 Endothelial activation and dysregulation in malaria: a potential target for novel therapeutics. Curr Opin Hematol 2011 0.99
54 Prosthetic joint infection due to "Helcococcus pyogenes" [corrected]. J Clin Microbiol 2004 0.98
55 Noninjurious mechanical ventilation activates a proinflammatory transcriptional program in the lung. Physiol Genomics 2009 0.98
56 Host immune response in returning travellers infected with malaria. Malar J 2012 0.96
57 Enterohemorrhagic Escherichia coli Infections and the Hemolytic-Uremic Syndrome. Med Clin North Am 2013 0.96
58 Fas and Fas-associated death domain protein regulate monocyte chemoattractant protein-1 expression by human smooth muscle cells through caspase- and calpain-dependent release of interleukin-1alpha. Circ Res 2003 0.95
59 Inflammatory pathways in malaria infection: TLRs share the stage with other components of innate immunity. Mol Biochem Parasitol 2008 0.94
60 Network analysis of transcriptional responses induced by mesenchymal stem cell treatment of experimental sepsis. Am J Pathol 2012 0.94
61 Slow Clearance of Plasmodium falciparum in Severe Pediatric Malaria, Uganda, 2011-2013. Emerg Infect Dis 2015 0.94
62 Colony-stimulating factors in the prevention and management of infectious diseases. Infect Dis Clin North Am 2011 0.93
63 Functional roles for C5a and C5aR but not C5L2 in the pathogenesis of human and experimental cerebral malaria. Infect Immun 2013 0.93
64 Dysregulation of angiopoietin 1 and 2 in Escherichia coli O157:H7 infection and the hemolytic-uremic syndrome. J Infect Dis 2013 0.92
65 Performance characteristics of combinations of host biomarkers to identify women with occult placental malaria: a case-control study from Malawi. PLoS One 2011 0.91
66 Lineage-specific growth factors can compensate for stem and progenitor cell deficiencies at the postprogenitor cell level: an analysis of doubly TPO- and G-CSF receptor-deficient mice. Blood 2002 0.90
67 Mechanical ventilation modulates Toll-like receptor-3-induced lung inflammation via a MyD88-dependent, TLR4-independent pathway: a controlled animal study. BMC Pulm Med 2010 0.90
68 Ischemia-reperfusion lung injury is attenuated in MyD88-deficient mice. PLoS One 2013 0.89
69 Nitric oxide for the adjunctive treatment of severe malaria: hypothesis and rationale. Med Hypotheses 2011 0.89
70 Broad-spectrum caspase inhibition paradoxically augments cell death in TNF-alpha -stimulated neutrophils. Blood 2002 0.89
71 Systemic dysregulation of angiopoietin-1/2 in streptococcal toxic shock syndrome. Clin Infect Dis 2011 0.88
72 Clinical utility of biomarkers of endothelial activation and coagulation for prognosis in HIV infection: a systematic review. Virulence 2013 0.87
73 Fas (CD95) induces rapid, TLR4/IRAK4-dependent release of pro-inflammatory HMGB1 from macrophages. J Inflamm (Lond) 2010 0.87
74 Adenosine triphosphate depletion of erythrocytes simulates the phenotype associated with pyruvate kinase deficiency and confers protection against Plasmodium falciparum in vitro. J Infect Dis 2009 0.86
75 ABO blood groups influence macrophage-mediated phagocytosis of Plasmodium falciparum-infected erythrocytes. PLoS Pathog 2012 0.86
76 Hyper-IgE syndrome is not associated with defects in several candidate toll-like receptor pathway genes. Hum Immunol 2005 0.86
77 Posaconazole: A new agent for the prevention and management of severe, refractory or invasive fungal infections. Can J Infect Dis Med Microbiol 2008 0.85
78 Statins fail to improve outcome in experimental cerebral malaria and potentiate Toll-like receptor-mediated cytokine production by murine macrophages. Am J Trop Med Hyg 2009 0.85
79 Mesenchymal stromal (stem) cell therapy fails to improve outcomes in experimental severe influenza. PLoS One 2013 0.85
80 CD36 deficiency attenuates experimental mycobacterial infection. BMC Infect Dis 2010 0.85
81 Effective storage of granulocytes collected by centrifugation leukapheresis from donors stimulated with granulocyte-colony-stimulating factor. Transfusion 2005 0.85
82 Endothelial activation biomarkers increase after HIV-1 acquisition: plasma vascular cell adhesion molecule-1 predicts disease progression. AIDS 2013 0.84
83 A prospective study of endothelial activation biomarkers, including plasma angiopoietin-1 and angiopoietin-2, in Kenyan women initiating antiretroviral therapy. BMC Infect Dis 2013 0.84
84 Broad spectrum of dermatologic manifestations caused by Mycobacterium haemophilum infection. Arch Dermatol 2002 0.84
85 Role of caspases in death and survival of the plaque macrophage. Arterioscler Thromb Vasc Biol 2005 0.84
86 A novel tissue-engineered approach to problems of the postpneumonectomy space. Ann Thorac Surg 2011 0.83
87 The p17 cleaved form of caspase-3 is present within viable macrophages in vitro and in atherosclerotic plaque. Arterioscler Thromb Vasc Biol 2003 0.83
88 Complement activation: a critical mediator of adverse fetal outcomes in placental malaria? Trends Parasitol 2011 0.83
89 Failure of two distinct anti-apoptotic approaches to reduce mortality in experimental cerebral malaria. Am J Trop Med Hyg 2008 0.83
90 Systemic release of high mobility group box 1 (HMGB1) protein is associated with severe and fatal Plasmodium falciparum malaria. Malar J 2013 0.82
91 Impact of a formal mentoring program on academic promotion of Department of Medicine faculty: a comparative study. Med Teach 2014 0.82
92 Performance of point-of-care diagnostics for glucose, lactate, and hemoglobin in the management of severe malaria in a resource-constrained hospital in Uganda. Am J Trop Med Hyg 2014 0.81
93 Effect of Chlamydia pneumoniae on cellular ATP content in mouse macrophages: role of Toll-like receptor 2. Infect Immun 2005 0.81
94 Delusional parasitosis: six-year experience with 23 consecutive cases at an academic medical center. Int J Infect Dis 2009 0.81
95 Delay in diagnosis: malaria in a returning traveller. CMAJ 2009 0.81
96 Herpes simplex virus type 2 serostatus is not associated with inflammatory or metabolic markers in antiretroviral therapy-treated HIV. AIDS Res Hum Retroviruses 2014 0.80
97 Stem cells and cell therapies in lung biology and diseases: conference report. Ann Am Thorac Soc 2013 0.80
98 Vestibular toxic effects induced by once-daily aminoglycoside therapy. Arch Otolaryngol Head Neck Surg 2005 0.80
99 Host biomarkers distinguish dengue from leptospirosis in Colombia: a case-control study. BMC Infect Dis 2014 0.80
100 Plasmodium falciparum shows transcriptional versatility within the human host. Trends Parasitol 2008 0.80
101 Establishing an antimicrobial stewardship program. Healthc Q 2010 0.79
102 Endothelial activation and dysfunction in the pathogenesis of microvascular obstruction in severe malaria--a viable target for therapeutic adjunctive intervention. J Infect Dis 2014 0.79
103 Mesenchymal stromal (stem) cells suppress pro-inflammatory cytokine production but fail to improve survival in experimental staphylococcal toxic shock syndrome. BMC Immunol 2014 0.79
104 Chlamydia pneumoniae augments the oxidized low-density lipoprotein-induced death of mouse macrophages by a caspase-independent pathway. Infect Immun 2005 0.78
105 Hematopoietic Fas deficiency does not affect experimental atherosclerotic lesion formation despite inducing a proatherogenic state. Am J Pathol 2011 0.78
106 Nonhematopoietic Peroxisome Proliferator-Activated Receptor-α Protects Against Cardiac Injury and Enhances Survival in Experimental Polymicrobial Sepsis. Crit Care Med 2016 0.78
107 Mutant elastase in pathogenesis of cyclic and severe congenital neutropenia. J Pediatr Hematol Oncol 2002 0.77
108 Elevated CXCL10 (IP-10) in bronchoalveolar lavage fluid is associated with acute cellular rejection after human lung transplantation. Transplantation 2014 0.77
109 Inhaled nitric oxide therapy fails to improve outcome in experimental severe influenza. Int J Med Sci 2012 0.76
110 Divergent roles of IRAK4-mediated innate immune responses in two experimental models of severe malaria. Am J Trop Med Hyg 2010 0.76
111 Granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, and other immunomodulatory therapies for the treatment of infectious diseases in solid organ transplant recipients. Curr Opin Organ Transplant 2008 0.76
112 Is angiopoietin-2 the key piece in the sepsis puzzle?*. Crit Care Med 2012 0.75
113 SYSTEM-WIDE MAPPING OF ACTIVATED CIRCUITRY IN EXPERIMENTAL SYSTEMIC INFLAMMATORY RESPONSE SYNDROME. Shock 2016 0.75
114 Special focus: endothelial activation/dysfunction. Virulence 2013 0.75
115 Brain-Derived Neurotrophic Factor is Associated with Disease Severity and Clinical Outcome in Ugandan Children Admitted to Hospital with Severe Malaria. Pediatr Infect Dis J 2016 0.75
116 Tularemia endocarditis from domestic pet exposure. Am J Med 2013 0.75