Published in J Psychiatr Res on December 08, 2009
Gene-environment interactions: early life stress and risk for depressive and anxiety disorders. Psychopharmacology (Berl) (2011) 1.30
Escitalopram, an antidepressant with an allosteric effect at the serotonin transporter--a review of current understanding of its mechanism of action. Psychopharmacology (Berl) (2011) 0.92
Altered functional protein networks in the prefrontal cortex and amygdala of victims of suicide. PLoS One (2012) 0.91
Chronic escitalopram treatment restores spatial learning, monoamine levels, and hippocampal long-term potentiation in an animal model of depression. Psychopharmacology (Berl) (2010) 0.83
Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease. Brain (2015) 0.81
Agomelatine: mechanism of action and pharmacological profile in relation to antidepressant properties. Br J Pharmacol (2014) 0.80
Early-life exposure to the SSRI paroxetine exacerbates depression-like behavior in anxiety/depression-prone rats. Neuroscience (2014) 0.78
Maternal separation enhances object location memory and prevents exercise-induced MAPK/ERK signalling in adult Sprague-Dawley rats. Metab Brain Dis (2012) 0.78
Synaptoproteomic analysis of a rat gene-environment model of depression reveals involvement of energy metabolism and cellular remodeling pathways. Int J Neuropsychopharmacol (2014) 0.78
Cannabinoids, Neurogenesis and Antidepressant Drugs: Is there a Link? Curr Neuropharmacol (2013) 0.75
Towards a glutamate hypothesis of depression: an emerging frontier of neuropsychopharmacology for mood disorders. Neuropharmacology (2011) 2.79
How can drug discovery for psychiatric disorders be improved? Nat Rev Drug Discov (2007) 2.29
L-acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors. Proc Natl Acad Sci U S A (2013) 1.94
Dynamic regulation of glutamatergic postsynaptic activity in rat prefrontal cortex by repeated administration of antipsychotic drugs. Mol Pharmacol (2008) 1.61
Signaling pathways regulating gene expression, neuroplasticity, and neurotrophic mechanisms in the action of antidepressants: a critical overview. Pharmacol Rev (2006) 1.51
Neuronal plasticity: a link between stress and mood disorders. Psychoneuroendocrinology (2009) 1.47
The Flinders Sensitive Line rat: a selectively bred putative animal model of depression. Neurosci Biobehav Rev (2005) 1.43
The antidepressant effect of running is associated with increased hippocampal cell proliferation. Int J Neuropsychopharmacol (2005) 1.36
Noradrenaline in mood and anxiety disorders: basic and clinical studies. Int Clin Psychopharmacol (2003) 1.34
Postnatal repeated maternal deprivation produces age-dependent changes of brain-derived neurotrophic factor expression in selected rat brain regions. Biol Psychiatry (2004) 1.32
Stress during development: Impact on neuroplasticity and relevance to psychopathology. Prog Neurobiol (2007) 1.31
Chronic antidepressants reduce depolarization-evoked glutamate release and protein interactions favoring formation of SNARE complex in hippocampus. J Neurosci (2005) 1.25
Running is rewarding and antidepressive. Physiol Behav (2007) 1.25
Selective phosphorylation of nuclear CREB by fluoxetine is linked to activation of CaM kinase IV and MAP kinase cascades. Neuropsychopharmacology (2004) 1.23
The neuropeptide Y (NPY)-ergic system is associated with behavioral resilience to stress exposure in an animal model of post-traumatic stress disorder. Neuropsychopharmacology (2011) 1.21
Understanding resilience. Front Behav Neurosci (2013) 1.19
Repeated exposure to cocaine differently modulates BDNF mRNA and protein levels in rat striatum and prefrontal cortex. Eur J Neurosci (2007) 1.17
Acute stress increases depolarization-evoked glutamate release in the rat prefrontal/frontal cortex: the dampening action of antidepressants. PLoS One (2010) 1.16
Quetiapine affects neuropeptide Y and corticotropin-releasing hormone in cerebrospinal fluid from schizophrenia patients: relationship to depression and anxiety symptoms and to treatment response. Int J Neuropsychopharmacol (2011) 1.14
Chronic heroin and cocaine abuse is associated with decreased serum concentrations of the nerve growth factor and brain-derived neurotrophic factor. J Psychopharmacol (2007) 1.10
Chronic duloxetine treatment induces specific changes in the expression of BDNF transcripts and in the subcellular localization of the neurotrophin protein. Neuropsychopharmacology (2007) 1.10
Chronic antidepressant treatments increase basic fibroblast growth factor and fibroblast growth factor-binding protein in neurons. Neuropharmacology (2008) 1.10
Blood microRNA changes in depressed patients during antidepressant treatment. Eur Neuropsychopharmacol (2012) 1.08
Regulation of editing and expression of glutamate alpha-amino-propionic-acid (AMPA)/kainate receptors by antidepressant drugs. Biol Psychiatry (2006) 1.05
Glucocorticoid receptor and FKBP5 expression is altered following exposure to chronic stress: modulation by antidepressant treatment. Neuropsychopharmacology (2012) 1.04
The action of antidepressants on the glutamate system: regulation of glutamate release and glutamate receptors. Biol Psychiatry (2012) 1.04
Association between promoter polymorphic haplotypes of interleukin-10 gene and schizophrenia. Biol Psychiatry (2002) 1.03
Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression. Int J Neuropsychopharmacol (2011) 1.03
Anxiolytic-like effect of the selective neuropeptide Y Y2 receptor antagonist BIIE0246 in the elevated plus-maze. Peptides (2006) 1.03
Acute stress responsiveness of the neurotrophin BDNF in the rat hippocampus is modulated by chronic treatment with the antidepressant duloxetine. Neuropsychopharmacology (2008) 1.02
Lithium treatment alters brain concentrations of nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor in a rat model of depression. Int J Neuropsychopharmacol (2003) 1.02
Mode of action of agomelatine: synergy between melatonergic and 5-HT2C receptors. World J Biol Psychiatry (2011) 1.02
Neuropeptide expression in rats exposed to chronic mild stresses. Psychopharmacology (Berl) (2004) 1.02
Fluoxetine and olanzapine have synergistic effects in the modulation of fibroblast growth factor 2 expression within the rat brain. Biol Psychiatry (2004) 1.00
The effects of social isolation on neuropeptide Y levels, exploratory and anxiety-related behaviors in rats. Pharmacol Biochem Behav (2006) 1.00
Increased CRF-like and NPY-like immunoreactivity in adult rats exposed to nicotine during adolescence: relation to anxiety-like and depressive-like behavior. Neuropeptides (2005) 0.99
Inverse correlation of brain and blood BDNF levels in a genetic rat model of depression. Int J Neuropsychopharmacol (2009) 0.99
Central functions of neuropeptide Y in mood and anxiety disorders. Expert Opin Ther Targets (2011) 0.99
Cellular and molecular mechanisms in the long-term action of antidepressants. Dialogues Clin Neurosci (2008) 0.99
Long-term citalopram administration reduces responsiveness of HPA axis in patients with major depression: relationship with S-citalopram concentrations in plasma and cerebrospinal fluid (CSF) and clinical response. Psychopharmacology (Berl) (2005) 0.98
Reduced neuroplasticity in aged rats: a role for the neurotrophin brain-derived neurotrophic factor. Neurobiol Aging (2013) 0.97
Early life stress changes concentrations of neuropeptide Y and corticotropin-releasing hormone in adult rat brain. Lithium treatment modifies these changes. Neuropsychopharmacology (2002) 0.97
Resting glutamate levels and rapid glutamate transients in the prefrontal cortex of the Flinders Sensitive Line rat: a genetic rodent model of depression. Neuropsychopharmacology (2011) 0.97
Prenatal stress elicits regionally selective changes in basal FGF-2 gene expression in adulthood and alters the adult response to acute or chronic stress. Neurobiol Dis (2005) 0.96
The pharmacological properties of antidepressants. Int Clin Psychopharmacol (2010) 0.96
Electroconvulsive stimuli selectively affect behavior and neuropeptide Y (NPY) and NPY Y(1) receptor gene expressions in hippocampus and hypothalamus of Flinders Sensitive Line rat model of depression. Eur Neuropsychopharmacol (2006) 0.96
Antidepressant treatments and function of glutamate ionotropic receptors mediating amine release in hippocampus. Neuropharmacology (2007) 0.96
Running has differential effects on NPY, opiates, and cell proliferation in an animal model of depression and controls. Neuropsychopharmacology (2006) 0.95
Early-life stress and antidepressants modulate peripheral biomarkers in a gene-environment rat model of depression. Prog Neuropsychopharmacol Biol Psychiatry (2010) 0.95
The antidepressant effects of running and escitalopram are associated with levels of hippocampal NPY and Y1 receptor but not cell proliferation in a rat model of depression. Hippocampus (2010) 0.95
Repeated stress prevents cocaine-induced activation of BDNF signaling in rat prefrontal cortex. Eur Neuropsychopharmacol (2009) 0.94
Effects of prolonged ethanol vapor exposure on forced swim behavior, and neuropeptide Y and corticotropin-releasing factor levels in rat brains. Alcohol (2010) 0.94
Physical exercise and antidepressants enhance BDNF targeting in hippocampal CA3 dendrites: further evidence of a spatial code for BDNF splice variants. Neuropsychopharmacology (2012) 0.94
Abnormal exocytotic release of glutamate in a mouse model of amyotrophic lateral sclerosis. J Neurochem (2011) 0.94
Differential expression of synaptic proteins after chronic restraint stress in rat prefrontal cortex and hippocampus. Brain Res (2011) 0.93
Dynamic regulation of fibroblast growth factor 2 (FGF-2) gene expression in the rat brain following single and repeated cocaine administration. J Neurochem (2006) 0.93
Corticostriatal brain-derived neurotrophic factor dysregulation in adult rats following prenatal stress. Eur J Neurosci (2004) 0.92
Developmental influence of the serotonin transporter on the expression of npas4 and GABAergic markers: modulation by antidepressant treatment. Neuropsychopharmacology (2011) 0.92
Social support in bipolar disorder: its relevance to remission and relapse. Bipolar Disord (2003) 0.92
Long-Term duloxetine treatment normalizes altered brain-derived neurotrophic factor expression in serotonin transporter knockout rats through the modulation of specific neurotrophin isoforms. Mol Pharmacol (2010) 0.92
Modulation of synaptic plasticity by stress and antidepressants. Bipolar Disord (2002) 0.92
Neuropeptide Y and corticotropin-releasing hormone in CSF mark response to antidepressive treatment with citalopram. Int J Neuropsychopharmacol (2005) 0.92
Early raise of BDNF in hippocampus suggests induction of posttranscriptional mechanisms by antidepressants. BMC Neurosci (2009) 0.91
Single session of cocaine intravenous self-administration shapes goal-oriented behaviours and up-regulates Arc mRNA levels in rat medial prefrontal cortex. Int J Neuropsychopharmacol (2008) 0.91
Remodelling by early-life stress of NMDA receptor-dependent synaptic plasticity in a gene-environment rat model of depression. Int J Neuropsychopharmacol (2008) 0.91
Neurotrophic factors and CNS disorders: findings in rodent models of depression and schizophrenia. Prog Brain Res (2004) 0.91
Antipsychotic drug actions on gene modulation and signaling mechanisms. Pharmacol Ther (2009) 0.91
Behavioural consequences of two chronic psychosocial stress paradigms: anxiety without depression. Psychoneuroendocrinology (2011) 0.91
Stress-induced changes of hippocampal NMDA receptors: modulation by duloxetine treatment. PLoS One (2012) 0.91
Chronic treatment with fluoxetine up-regulates cellular BDNF mRNA expression in rat dopaminergic regions. Int J Neuropsychopharmacol (2005) 0.90
Adult life behavioral consequences of early maternal separation are alleviated by escitalopram treatment in a rat model of depression. Prog Neuropsychopharmacol Biol Psychiatry (2006) 0.90
Expression profiling of a genetic animal model of depression reveals novel molecular pathways underlying depressive-like behaviours. PLoS One (2010) 0.90
Chronic antidepressants induce redistribution and differential activation of alphaCaM kinase II between presynaptic compartments. Neuropsychopharmacology (2007) 0.90