Published in Neuropsychopharmacology on October 19, 2011
Glucocorticoid receptor and FKBP5 expression is altered following exposure to chronic stress: modulation by antidepressant treatment. Neuropsychopharmacology (2012) 1.04
Npas4: a neuronal transcription factor with a key role in social and cognitive functions relevant to developmental disorders. PLoS One (2012) 1.03
Prenatal immune activation induces maturation-dependent alterations in the prefrontal GABAergic transcriptome. Schizophr Bull (2013) 1.00
The effects of maternal depression and maternal selective serotonin reuptake inhibitor exposure on offspring. Front Cell Neurosci (2013) 0.94
Effects of developmental lead exposure on the hippocampal transcriptome: influences of sex, developmental period, and lead exposure level. Toxicol Sci (2012) 0.89
Behavioral effects of the benzodiazepine-positive allosteric modulator SH-053-2'F-S-CH₃ in an immune-mediated neurodevelopmental disruption model. Int J Neuropsychopharmacol (2015) 0.82
Overexpression of BDNF increases excitability of the lumbar spinal network and leads to robust early locomotor recovery in completely spinalized rats. PLoS One (2014) 0.81
Npas4: Linking Neuronal Activity to Memory. Trends Neurosci (2016) 0.81
Repeated administration of imipramine modifies GABAergic transmission in rat frontal cortex. J Neural Transm (Vienna) (2012) 0.79
5-HT2C receptor desensitization moderates anxiety in 5-HTT deficient mice: from behavioral to cellular evidence. Int J Neuropsychopharmacol (2014) 0.77
Decreased expression of neuronal Per-Arnt-Sim domain protein 4 gene in the hippocampus of a post-stroke depression rat model. Exp Ther Med (2014) 0.76
Reduced Inhibition within Layer IV of Sert Knockout Rat Barrel Cortex is Associated with Faster Sensory Integration. Cereb Cortex (2017) 0.75
Reward Network Immediate Early Gene Expression in Mood Disorders. Front Behav Neurosci (2017) 0.75
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science (2003) 28.61
Cortical inhibitory neurons and schizophrenia. Nat Rev Neurosci (2005) 11.68
Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks. Nat Rev Neurosci (2007) 8.76
The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation. Arch Gen Psychiatry (2011) 6.66
The molecular neurobiology of depression. Nature (2008) 6.51
Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits. Am J Psychiatry (2010) 6.15
The PAS superfamily: sensors of environmental and developmental signals. Annu Rev Pharmacol Toxicol (2000) 4.79
New approaches to antidepressant drug discovery: beyond monoamines. Nat Rev Neurosci (2006) 4.62
GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder. Neuropsychopharmacology (2001) 4.41
Stress, depression, and neuroplasticity: a convergence of mechanisms. Neuropsychopharmacology (2007) 4.38
Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice. Science (2004) 4.31
Mouse and rat BDNF gene structure and expression revisited. J Neurosci Res (2007) 4.13
Activity-dependent regulation of inhibitory synapse development by Npas4. Nature (2008) 4.10
Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications. Biol Psychiatry (2008) 4.06
From synapse to nucleus: calcium-dependent gene transcription in the control of synapse development and function. Neuron (2008) 4.02
New insights into BDNF function in depression and anxiety. Nat Neurosci (2007) 3.94
Genetics of emotional regulation: the role of the serotonin transporter in neural function. Trends Cogn Sci (2006) 3.92
Gene X environment interactions at the serotonin transporter locus. Biol Psychiatry (2008) 3.80
The developmental role of serotonin: news from mouse molecular genetics. Nat Rev Neurosci (2003) 3.79
The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis. Mol Psychiatry (2007) 3.34
Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus. J Neurosci (1996) 3.33
Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments. Mol Psychiatry (2002) 3.01
Reduced cortical gamma-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy. Arch Gen Psychiatry (1999) 2.78
Role of neurotrophic factors in depression. Curr Opin Pharmacol (2006) 2.39
Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with selective serotonin reuptake inhibitor efficacy in depressed patients. Mol Psychiatry (2006) 2.29
Targeting the murine serotonin transporter: insights into human neurobiology. Nat Rev Neurosci (2008) 2.21
Is mood chemistry? Nat Rev Neurosci (2005) 2.12
Inhibition of serotonin but not norepinephrine transport during development produces delayed, persistent perturbations of emotional behaviors in mice. J Neurosci (2008) 2.11
GABAergic dysfunction in mood disorders. Mol Psychiatry (2003) 2.01
Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors. Am J Psychiatry (2002) 1.99
Looking on the bright side of serotonin transporter gene variation. Biol Psychiatry (2010) 1.94
'New' functions for 'old' proteins: the role of the calcium-binding proteins calbindin D-28k, calretinin and parvalbumin, in cerebellar physiology. Studies with knockout mice. Cerebellum (2002) 1.87
cAMP response element-mediated gene transcription is upregulated by chronic antidepressant treatment. J Neurosci (2000) 1.86
The GABAergic deficit hypothesis of major depressive disorder. Mol Psychiatry (2010) 1.80
Is it time to reassess the BDNF hypothesis of depression? Mol Psychiatry (2007) 1.80
Serotonergic vulnerability and depression: assumptions, experimental evidence and implications. Mol Psychiatry (2006) 1.76
Molecular determinants of dysregulated GABAergic gene expression in the prefrontal cortex of subjects with schizophrenia. Biol Psychiatry (2009) 1.71
Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis. Pharmacogenet Genomics (2006) 1.60
Neuronal plasticity: a link between stress and mood disorders. Psychoneuroendocrinology (2009) 1.47
Characterization of the serotonin transporter knockout rat: a selective change in the functioning of the serotonergic system. Neuroscience (2007) 1.47
Critical role of promoter IV-driven BDNF transcription in GABAergic transmission and synaptic plasticity in the prefrontal cortex. Proc Natl Acad Sci U S A (2009) 1.46
Lasting syndrome of depression produced by reduction in serotonin uptake during postnatal development: evidence from sleep, stress, and behavior. J Neurosci (2008) 1.40
Identification of cis-elements and transcription factors regulating neuronal activity-dependent transcription of human BDNF gene. J Neurosci (2011) 1.40
Brain-derived neurotrophic factor promotes the maturation of GABAergic mechanisms in cultured hippocampal neurons. J Neurosci (2002) 1.35
Specificity and timing of neocortical transcriptome changes in response to BDNF gene ablation during embryogenesis or adulthood. Mol Psychiatry (2006) 1.30
Fluoxetine increases the activity of the ERK-CREB signal system and alleviates the depressive-like behavior in rats exposed to chronic forced swim stress. Neurobiol Dis (2008) 1.28
Moderation of antidepressant response by the serotonin transporter gene. Br J Psychiatry (2009) 1.25
Association between serotonin transporter gene promoter polymorphism (5HTTLPR) and behavioral responses to tryptophan depletion in healthy women with and without family history of depression. Arch Gen Psychiatry (2002) 1.24
A study in male and female 5-HT transporter knockout rats: an animal model for anxiety and depression disorders. Neuroscience (2008) 1.22
Reduced somatostatin in subgenual anterior cingulate cortex in major depression. Neurobiol Dis (2011) 1.13
Brain-derived neurotrophic factor and antidepressant activity. Curr Pharm Des (2005) 1.12
The age-dependent effects of selective serotonin reuptake inhibitors in humans and rodents: A review. Prog Neuropsychopharmacol Biol Psychiatry (2010) 1.11
Chronic duloxetine treatment induces specific changes in the expression of BDNF transcripts and in the subcellular localization of the neurotrophin protein. Neuropsychopharmacology (2007) 1.10
Conserved role for the serotonin transporter gene in rat and mouse neurobehavioral endophenotypes. Neurosci Biobehav Rev (2009) 1.10
CREB, neurogenesis and depression. Bioessays (2007) 1.07
Chronic stress decreases the number of parvalbumin-immunoreactive interneurons in the hippocampus: prevention by treatment with a substance P receptor (NK1) antagonist. Neuropsychopharmacology (2005) 1.07
Reduced level of glutamic acid decarboxylase-67 kDa in the prefrontal cortex in major depression. Int J Neuropsychopharmacol (2009) 1.05
Acute stress responsiveness of the neurotrophin BDNF in the rat hippocampus is modulated by chronic treatment with the antidepressant duloxetine. Neuropsychopharmacology (2008) 1.02
Fluoxetine exerts age-dependent effects on behavior and amygdala neuroplasticity in the rat. PLoS One (2011) 1.01
Lack of promoter IV-driven BDNF transcription results in depression-like behavior. Genes Brain Behav (2010) 1.00
Neonatal administration of the selective serotonin reuptake inhibitor Lu 10-134-C increases forced swimming-induced immobility in adult rats: a putative animal model of depression? J Pharmacol Exp Ther (1997) 1.00
Low plasma gamma-aminobutyric acid levels in male patients with depression. Biol Psychiatry (1992) 0.99
CSF GABA in normal subjects and patients with depression, schizophrenia, mania, and anorexia nervosa. Am J Psychiatry (1981) 0.98
Cerebrospinal fluid gamma-aminobutyric acid and homovanillic acid in depressive disorders. Biol Psychiatry (1982) 0.95
Long-Term duloxetine treatment normalizes altered brain-derived neurotrophic factor expression in serotonin transporter knockout rats through the modulation of specific neurotrophin isoforms. Mol Pharmacol (2010) 0.92
Behavioral evaluation of male and female mice pups exposed to fluoxetine during pregnancy and lactation. Pharmacology (2007) 0.91
Duloxetine: a review of its use in the treatment of generalized anxiety disorder. CNS Drugs (2009) 0.91
Fluoxetine administration to pregnant rats increases anxiety-related behavior in the offspring. Psychopharmacology (Berl) (2011) 0.91
CSF neurochemistry in depressed, manic, and schizophrenic patients compared with that of normal controls. Am J Psychiatry (1984) 0.90
Reduced function of the serotonin transporter is associated with decreased expression of BDNF in rodents as well as in humans. Neurobiol Dis (2009) 0.89
Antistress properties of antidepressant drugs and their clinical implications. Pharmacol Ther (2011) 0.87
Characterization of functional heterodimer partners in brain for a bHLH-PAS factor NXF. Biochim Biophys Acta (2009) 0.83
Repeated neonatal separation stress alters the composition of neurochemically characterized interneuron subpopulations in the rodent dentate gyrus and basolateral amygdala. Dev Neurobiol (2008) 0.83
Altered expression and modulation of activity-regulated cytoskeletal associated protein (Arc) in serotonin transporter knockout rats. Eur Neuropsychopharmacol (2009) 0.81
Controllability and duration of stress alter central nervous system depressant-induced sleep time in rats. Behav Neurosci (1992) 0.80
The interaction between acute oligomer Abeta(1-40) and stress severely impaired spatial learning and memory. Neurobiol Learn Mem (2009) 0.78
Stress in puberty unmasks latent neuropathological consequences of prenatal immune activation in mice. Science (2013) 3.83
Is lobectomy really more effective than sublobar resection in the surgical treatment of second primary lung cancer? Eur J Cardiothorac Surg (2013) 2.18
Serum and plasma BDNF levels in major depression: a replication study and meta-analyses. World J Biol Psychiatry (2010) 1.70
Dynamic regulation of glutamatergic postsynaptic activity in rat prefrontal cortex by repeated administration of antipsychotic drugs. Mol Pharmacol (2008) 1.61
Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis. Pharmacogenet Genomics (2006) 1.60
Signaling pathways regulating gene expression, neuroplasticity, and neurotrophic mechanisms in the action of antidepressants: a critical overview. Pharmacol Rev (2006) 1.51
Neuronal plasticity: a link between stress and mood disorders. Psychoneuroendocrinology (2009) 1.47
Noradrenaline in mood and anxiety disorders: basic and clinical studies. Int Clin Psychopharmacol (2003) 1.34
A critical review of sex differences in decision-making tasks: focus on the Iowa Gambling Task. Behav Brain Res (2012) 1.34
Postnatal repeated maternal deprivation produces age-dependent changes of brain-derived neurotrophic factor expression in selected rat brain regions. Biol Psychiatry (2004) 1.32
Stress during development: Impact on neuroplasticity and relevance to psychopathology. Prog Neurobiol (2007) 1.31
Chronic antidepressants reduce depolarization-evoked glutamate release and protein interactions favoring formation of SNARE complex in hippocampus. J Neurosci (2005) 1.25
Role for the kinase SGK1 in stress, depression, and glucocorticoid effects on hippocampal neurogenesis. Proc Natl Acad Sci U S A (2013) 1.23
Selective phosphorylation of nuclear CREB by fluoxetine is linked to activation of CaM kinase IV and MAP kinase cascades. Neuropsychopharmacology (2004) 1.23
Repeated exposure to cocaine differently modulates BDNF mRNA and protein levels in rat striatum and prefrontal cortex. Eur J Neurosci (2007) 1.17
Acute stress increases depolarization-evoked glutamate release in the rat prefrontal/frontal cortex: the dampening action of antidepressants. PLoS One (2010) 1.16
Glucocorticoid-related molecular signaling pathways regulating hippocampal neurogenesis. Neuropsychopharmacology (2012) 1.16
Chronic duloxetine treatment induces specific changes in the expression of BDNF transcripts and in the subcellular localization of the neurotrophin protein. Neuropsychopharmacology (2007) 1.10
CREB, neurogenesis and depression. Bioessays (2007) 1.07
Regulation of editing and expression of glutamate alpha-amino-propionic-acid (AMPA)/kainate receptors by antidepressant drugs. Biol Psychiatry (2006) 1.05
Glucocorticoid receptor and FKBP5 expression is altered following exposure to chronic stress: modulation by antidepressant treatment. Neuropsychopharmacology (2012) 1.04
The puzzle box as a simple and efficient behavioral test for exploring impairments of general cognition and executive functions in mouse models of schizophrenia. Exp Neurol (2010) 1.03
A prospective randomized trial comparing stapler and laser techniques for interlobar fissure completion during pulmonary lobectomy. Lasers Med Sci (2012) 1.03
Mode of action of agomelatine: synergy between melatonergic and 5-HT2C receptors. World J Biol Psychiatry (2011) 1.02
Acute stress responsiveness of the neurotrophin BDNF in the rat hippocampus is modulated by chronic treatment with the antidepressant duloxetine. Neuropsychopharmacology (2008) 1.02
Fluoxetine and olanzapine have synergistic effects in the modulation of fibroblast growth factor 2 expression within the rat brain. Biol Psychiatry (2004) 1.00
Prenatal immune activation induces maturation-dependent alterations in the prefrontal GABAergic transcriptome. Schizophr Bull (2013) 1.00
The effect of COMT Val158 Met genotype on decision-making and preliminary findings on its interaction with the 5-HTTLPR in healthy females. Neuropharmacology (2008) 0.99
Reduced neuroplasticity in aged rats: a role for the neurotrophin brain-derived neurotrophic factor. Neurobiol Aging (2013) 0.97
Prenatal stress elicits regionally selective changes in basal FGF-2 gene expression in adulthood and alters the adult response to acute or chronic stress. Neurobiol Dis (2005) 0.96
Antidepressant treatments and function of glutamate ionotropic receptors mediating amine release in hippocampus. Neuropharmacology (2007) 0.96
Repeated stress prevents cocaine-induced activation of BDNF signaling in rat prefrontal cortex. Eur Neuropsychopharmacol (2009) 0.94
Abnormal exocytotic release of glutamate in a mouse model of amyotrophic lateral sclerosis. J Neurochem (2011) 0.94
The expression of VGF is reduced in leukocytes of depressed patients and it is restored by effective antidepressant treatment. Neuropsychopharmacology (2010) 0.93
Dynamic regulation of fibroblast growth factor 2 (FGF-2) gene expression in the rat brain following single and repeated cocaine administration. J Neurochem (2006) 0.93
Corticostriatal brain-derived neurotrophic factor dysregulation in adult rats following prenatal stress. Eur J Neurosci (2004) 0.92
Long-Term duloxetine treatment normalizes altered brain-derived neurotrophic factor expression in serotonin transporter knockout rats through the modulation of specific neurotrophin isoforms. Mol Pharmacol (2010) 0.92
Orbitofrontal cortex and amygdalar over-activity is associated with an inability to use the value of expected outcomes to guide behaviour in serotonin transporter knockout rats. Neurobiol Learn Mem (2010) 0.92
Modulation of synaptic plasticity by stress and antidepressants. Bipolar Disord (2002) 0.92
Early raise of BDNF in hippocampus suggests induction of posttranscriptional mechanisms by antidepressants. BMC Neurosci (2009) 0.91
Single session of cocaine intravenous self-administration shapes goal-oriented behaviours and up-regulates Arc mRNA levels in rat medial prefrontal cortex. Int J Neuropsychopharmacol (2008) 0.91
Antipsychotic drug actions on gene modulation and signaling mechanisms. Pharmacol Ther (2009) 0.91
Remodelling by early-life stress of NMDA receptor-dependent synaptic plasticity in a gene-environment rat model of depression. Int J Neuropsychopharmacol (2008) 0.91
Stress-induced changes of hippocampal NMDA receptors: modulation by duloxetine treatment. PLoS One (2012) 0.91
Chronic treatment with fluoxetine up-regulates cellular BDNF mRNA expression in rat dopaminergic regions. Int J Neuropsychopharmacol (2005) 0.90
Cross-species approaches to pathological gambling: a review targeting sex differences, adolescent vulnerability and ecological validity of research tools. Neurosci Biobehav Rev (2013) 0.90
Chronic antidepressants induce redistribution and differential activation of alphaCaM kinase II between presynaptic compartments. Neuropsychopharmacology (2007) 0.90
Corticostriatal up-regulation of activity-regulated cytoskeletal-associated protein expression after repeated exposure to cocaine. Mol Pharmacol (2006) 0.89
Reduced function of the serotonin transporter is associated with decreased expression of BDNF in rodents as well as in humans. Neurobiol Dis (2009) 0.89
Stress, glucocorticoids and glutamate release: effects of antidepressant drugs. Neurochem Int (2011) 0.89
Prenatal stress alters glutamatergic system responsiveness in adult rat prefrontal cortex. J Neurochem (2009) 0.89
Emerging role of the FGF system in psychiatric disorders. Trends Pharmacol Sci (2005) 0.88
Blood pressure in mutant rats lacking the 5-hydroxytryptamine transporter. Hypertension (2006) 0.88
Deletion of the serotonin transporter in rats disturbs serotonin homeostasis without impairing liver regeneration. Am J Physiol Gastrointest Liver Physiol (2009) 0.88
Synergistic mechanisms in the modulation of the neurotrophin BDNF in the rat prefrontal cortex following acute agomelatine administration. World J Biol Psychiatry (2010) 0.88
Time-dependent biphasic modulation of human BDNF by antidepressants in neuroblastoma cells. BMC Neurosci (2008) 0.88
Chronic phencyclidine administration reduces the expression and editing of specific glutamate receptors in rat prefrontal cortex. Exp Neurol (2007) 0.88
Effect of antipsychotic drugs on brain-derived neurotrophic factor expression under reduced N-methyl-D-aspartate receptor activity. J Neurosci Res (2003) 0.88
Sub-chronic exposure to atomoxetine up-regulates BDNF expression and signalling in the brain of adolescent spontaneously hypertensive rats: comparison with methylphenidate. Pharmacol Res (2010) 0.88
Single exposure to erythropoietin modulates Nerve Growth Factor expression in the spinal cord following traumatic injury: comparison with methylprednisolone. Eur J Pharmacol (2007) 0.87
Environmental enrichment ameliorates depressive-like symptoms in young rats bred for learned helplessness. Behav Brain Res (2013) 0.87
Antistress properties of antidepressant drugs and their clinical implications. Pharmacol Ther (2011) 0.87
Stress and cocaine interact to modulate basic fibroblast growth factor (FGF-2) expression in rat brain. Psychopharmacology (Berl) (2007) 0.86
Modulation of BDNF expression by repeated treatment with the novel antipsychotic lurasidone under basal condition and in response to acute stress. Int J Neuropsychopharmacol (2011) 0.86
Region-specific effects on BDNF expression after contingent or non-contingent cocaine i.v. self-administration in rats. Int J Neuropsychopharmacol (2012) 0.86
Acute spinal cord injury persistently reduces R/G RNA editing of AMPA receptors. J Neurochem (2010) 0.85
High serotonin levels during brain development alter the structural input-output connectivity of neural networks in the rat somatosensory layer IV. Front Cell Neurosci (2013) 0.85
Quetiapine regulates FGF-2 and BDNF expression in the hippocampus of animals treated with MK-801. Neuroreport (2004) 0.85
Differential c-Fos induction by different NMDA receptor antagonists with antidepressant efficacy: potential clinical implications. Int J Neuropsychopharmacol (2009) 0.85
Reduced CREB phosphorylation after chronic lithium treatment is associated with down-regulation of CaM kinase IV in rat hippocampus. Int J Neuropsychopharmacol (2006) 0.84
Selective regulation of presynaptic calcium/calmodulin-dependent protein kinase II by psychotropic drugs. Biol Psychiatry (2003) 0.84
Early induction of CREB activation and CREB-regulating signalling by antidepressants. Int J Neuropsychopharmacol (2009) 0.84
Repeated electroconvulsive shock (ECS) alters the phosphorylation of glutamate receptor subunits in the rat hippocampus. Int J Neuropsychopharmacol (2010) 0.83
Blockade of stress-induced increase of glutamate release in the rat prefrontal/frontal cortex by agomelatine involves synergy between melatonergic and 5-HT2C receptor-dependent pathways. BMC Neurosci (2010) 0.83
Prenatal versus postnatal maternal factors in the development of infection-induced working memory impairments in mice. Brain Behav Immun (2013) 0.83