Published in Structure on December 09, 2009
Molecular mechanism of scanning and start codon selection in eukaryotes. Microbiol Mol Biol Rev (2011) 2.51
Putting the pieces together: integrative modeling platform software for structure determination of macromolecular assemblies. PLoS Biol (2012) 2.37
Structures of the human and Drosophila 80S ribosome. Nature (2013) 2.36
RACK1, A multifaceted scaffolding protein: Structure and function. Cell Commun Signal (2011) 2.16
Ribosome assembly factors prevent premature translation initiation by 40S assembly intermediates. Science (2011) 2.01
Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution. Proc Natl Acad Sci U S A (2010) 1.99
One core, two shells: bacterial and eukaryotic ribosomes. Nat Struct Mol Biol (2012) 1.77
Localization of eukaryote-specific ribosomal proteins in a 5.5-Å cryo-EM map of the 80S eukaryotic ribosome. Proc Natl Acad Sci U S A (2010) 1.68
The small subunit processome in ribosome biogenesis—progress and prospects. Wiley Interdiscip Rev RNA (2011) 1.66
Receptor for activated C kinase 1 stimulates nascent polypeptide-dependent translation arrest. EMBO Rep (2010) 1.59
Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits. J Cell Biol (2010) 1.58
Molecular species identification of Central European ground beetles (Coleoptera: Carabidae) using nuclear rDNA expansion segments and DNA barcodes. Front Zool (2010) 1.50
Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1α complex. Proc Natl Acad Sci U S A (2010) 1.35
Mechanisms and implications of programmed translational frameshifting. Wiley Interdiscip Rev RNA (2012) 1.34
The C-terminal region of eukaryotic translation initiation factor 3a (eIF3a) promotes mRNA recruitment, scanning, and, together with eIF3j and the eIF3b RNA recognition motif, selection of AUG start codons. Mol Cell Biol (2010) 1.31
Trajectories of the ribosome as a Brownian nanomachine. Proc Natl Acad Sci U S A (2014) 1.29
The structure and function of the eukaryotic ribosome. Cold Spring Harb Perspect Biol (2012) 1.28
Structure and dynamics of the mammalian ribosomal pretranslocation complex. Mol Cell (2011) 1.28
'Ribozoomin'--translation initiation from the perspective of the ribosome-bound eukaryotic initiation factors (eIFs). Curr Protein Pept Sci (2012) 1.25
Assembly of Saccharomyces cerevisiae 60S ribosomal subunits: role of factors required for 27S pre-rRNA processing. EMBO J (2011) 1.22
The RNA recognition motif of eukaryotic translation initiation factor 3g (eIF3g) is required for resumption of scanning of posttermination ribosomes for reinitiation on GCN4 and together with eIF3i stimulates linear scanning. Mol Cell Biol (2010) 1.21
The eIF3c/NIP1 PCI domain interacts with RNA and RACK1/ASC1 and promotes assembly of translation preinitiation complexes. Nucleic Acids Res (2011) 1.09
Protein-protein interactions within late pre-40S ribosomes. PLoS One (2011) 1.07
Eukaryotic rpL10 drives ribosomal rotation. Nucleic Acids Res (2013) 1.05
The human RPS4 paralogue on Yq11.223 encodes a structurally conserved ribosomal protein and is preferentially expressed during spermatogenesis. BMC Mol Biol (2010) 1.03
Structural analysis of an eIF3 subcomplex reveals conserved interactions required for a stable and proper translation pre-initiation complex assembly. Nucleic Acids Res (2011) 1.03
Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis. Nucleic Acids Res (2010) 1.01
A molecular clamp ensures allosteric coordination of peptidyltransfer and ligand binding to the ribosomal A-site. Nucleic Acids Res (2010) 1.00
High throughput structural analysis of yeast ribosomes using hSHAPE. RNA Biol (2011) 0.99
Structural basis for the binding of IRES RNAs to the head of the ribosomal 40S subunit. Nucleic Acids Res (2011) 0.99
Characterization of the Interaction between hantavirus nucleocapsid protein (N) and ribosomal protein S19 (RPS19). J Biol Chem (2011) 0.97
Exploring the spatial and temporal organization of a cell's proteome. J Struct Biol (2010) 0.97
A flexible loop in yeast ribosomal protein L11 coordinates P-site tRNA binding. Nucleic Acids Res (2010) 0.96
Comparison of Segger and other methods for segmentation and rigid-body docking of molecular components in cryo-EM density maps. Biopolymers (2012) 0.96
Small ribosomal protein RPS0 stimulates translation initiation by mediating 40S-binding of eIF3 via its direct contact with the eIF3a/TIF32 subunit. PLoS One (2012) 0.94
Interaction of hantavirus nucleocapsid protein with ribosomal protein S19. J Virol (2010) 0.93
Structure and mechanical properties of the ribosomal L1 stalk three-way junction. Nucleic Acids Res (2012) 0.91
Yeast 18 S rRNA is directly involved in the ribosomal response to stringent AUG selection during translation initiation. J Biol Chem (2010) 0.91
A unique box in 28S rRNA is shared by the enigmatic insect order Zoraptera and Dictyoptera. PLoS One (2013) 0.91
An extensive network of information flow through the B1b/c intersubunit bridge of the yeast ribosome. PLoS One (2011) 0.90
Purification, characterization and crystallization of the human 80S ribosome. Nucleic Acids Res (2014) 0.89
siRNA knockdown of ribosomal protein gene RPL19 abrogates the aggressive phenotype of human prostate cancer. PLoS One (2011) 0.89
TEMPy: a Python library for assessment of three-dimensional electron microscopy density fits. J Appl Crystallogr (2015) 0.87
Modeling protein assemblies in the proteome. Mol Cell Proteomics (2014) 0.87
Potential key bases of ribosomal RNA to kingdom-specific spectra of antibiotic susceptibility and the possible archaeal origin of eukaryotes. PLoS One (2012) 0.87
Absence of knots in known RNA structures. Proc Natl Acad Sci U S A (2015) 0.87
Eukaryotic cells producing ribosomes deficient in Rpl1 are hypersensitive to defects in the ubiquitin-proteasome system. PLoS One (2011) 0.86
Mutations of highly conserved bases in the peptidyltransferase center induce compensatory rearrangements in yeast ribosomes. RNA (2011) 0.86
Yeast ribosomal protein L40 assembles late into precursor 60 S ribosomes and is required for their cytoplasmic maturation. J Biol Chem (2012) 0.85
Production of active recombinant eIF5A: reconstitution in E.coli of eukaryotic hypusine modification of eIF5A by its coexpression with modifying enzymes. Protein Eng Des Sel (2010) 0.84
Nucleolar trafficking of the mouse mammary tumor virus gag protein induced by interaction with ribosomal protein L9. J Virol (2012) 0.84
Maize ZmRACK1 is involved in the plant response to fungal phytopathogens. Int J Mol Sci (2014) 0.83
Identification of novel proteins associated with yeast snR30 small nucleolar RNA. Nucleic Acids Res (2011) 0.83
Characterization of hibernating ribosomes in mammalian cells. Cell Cycle (2011) 0.82
Eukaryote-specific rRNA expansion segments function in ribosome biogenesis. RNA (2016) 0.81
Conformational changes in the P site and mRNA entry channel evoked by AUG recognition in yeast translation preinitiation complexes. Nucleic Acids Res (2015) 0.81
Ribosome-associated Asc1/RACK1 is required for endonucleolytic cleavage induced by stalled ribosome at the 3' end of nonstop mRNA. Sci Rep (2016) 0.81
Ribosomes in the balance: structural equilibrium ensures translational fidelity and proper gene expression. Nucleic Acids Res (2014) 0.79
Specialized yeast ribosomes: a customized tool for selective mRNA translation. PLoS One (2013) 0.79
A central fragment of ribosomal protein S26 containing the eukaryote-specific motif YxxPKxYxK is a key component of the ribosomal binding site of mRNA region 5' of the E site codon. Nucleic Acids Res (2011) 0.79
The central core region of yeast ribosomal protein L11 is important for subunit joining and translational fidelity. Mol Genet Genomics (2011) 0.79
Regulatory Roles of Rpl22 in Hematopoiesis: An Old Dog with New Tricks. Crit Rev Immunol (2015) 0.77
The Not4 RING E3 Ligase: A Relevant Player in Cotranslational Quality Control. ISRN Mol Biol (2013) 0.77
A local-optimization refinement algorithm in single particle analysis for macromolecular complex with multiple rigid modules. Protein Cell (2015) 0.77
From DNA to proteins via the ribosome: structural insights into the workings of the translation machinery. Hum Genomics (2010) 0.76
Influence of translation factor activities on start site selection in six different mRNAs. Translation (Austin) (2013) 0.76
Ribosomal protein uS19 mutants reveal its role in coordinating ribosome structure and function. Translation (Austin) (2015) 0.76
Trans-kingdom mimicry underlies ribosome customization by a poxvirus kinase. Nature (2017) 0.76
CHOYCE: a web server for constrained homology modelling with cryoEM maps. Bioinformatics (2010) 0.75
Structure of the 40S ribosomal subunit of Plasmodium falciparum by homology and de novo modeling. Acta Pharm Sin B (2016) 0.75
Expanding the ribosomal universe. Structure (2009) 0.75
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res (1997) 665.31
Identification of common molecular subsequences. J Mol Biol (1981) 130.53
UCSF Chimera--a visualization system for exploratory research and analysis. J Comput Chem (2004) 112.47
Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res (2003) 77.89
Comparative protein modelling by satisfaction of spatial restraints. J Mol Biol (1993) 64.61
Protein structure prediction on the Web: a case study using the Phyre server. Nat Protoc (2009) 32.64
The comparative RNA web (CRW) site: an online database of comparative sequence and structure information for ribosomal, intron, and other RNAs. BMC Bioinformatics (2002) 29.41
Comparative anatomy of 16-S-like ribosomal RNA. Prog Nucleic Acid Res Mol Biol (1985) 16.21
The economics of ribosome biosynthesis in yeast. Trends Biochem Sci (1999) 15.22
Structures of the bacterial ribosome at 3.5 A resolution. Science (2005) 12.63
Statistical potential for assessment and prediction of protein structures. Protein Sci (2006) 8.98
Identification of RPS14 as a 5q- syndrome gene by RNA interference screen. Nature (2008) 8.38
The European database on small subunit ribosomal RNA. Nucleic Acids Res (2002) 7.80
Locking and unlocking of ribosomal motions. Cell (2003) 6.59
Structure of the 80S ribosome from Saccharomyces cerevisiae--tRNA-ribosome and subunit-subunit interactions. Cell (2001) 5.01
Extraribosomal functions of ribosomal proteins. Trends Biochem Sci (1996) 4.25
Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation. EMBO J (2004) 3.69
Tools for comparative protein structure modeling and analysis. Nucleic Acids Res (2003) 3.68
Ribosomal protein S24 gene is mutated in Diamond-Blackfan anemia. Am J Hum Genet (2006) 3.17
Protein structure fitting and refinement guided by cryo-EM density. Structure (2008) 3.12
Structural basis for the function of the ribosomal L7/12 stalk in factor binding and GTPase activation. Cell (2005) 2.97
Statistical potentials for fold assessment. Protein Sci (2002) 2.92
Alignment of protein sequences by their profiles. Protein Sci (2004) 2.80
Ribosomal protein S17 gene (RPS17) is mutated in Diamond-Blackfan anemia. Hum Mutat (2007) 2.73
The combination of symbolic and numerical computation for three-dimensional modeling of RNA. Science (1991) 2.66
Roles of eukaryotic ribosomal proteins in maturation and transport of pre-18S rRNA and ribosome function. Mol Cell (2005) 2.65
Structural basis for mRNA and tRNA positioning on the ribosome. Proc Natl Acad Sci U S A (2006) 2.55
Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation. EMBO J (2007) 2.48
The process of mRNA-tRNA translocation. Proc Natl Acad Sci U S A (2007) 2.45
Formation of the first peptide bond: the structure of EF-P bound to the 70S ribosome. Science (2009) 2.33
Regulation of eukaryotic translation by the RACK1 protein: a platform for signalling molecules on the ribosome. EMBO Rep (2004) 2.28
Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM. Nat Struct Mol Biol (2004) 2.27
Ribosomal position and contacts of mRNA in eukaryotic translation initiation complexes. EMBO J (2008) 2.26
Impaired ribosome biogenesis in Diamond-Blackfan anemia. Blood (2006) 2.16
Software extensions to UCSF chimera for interactive visualization of large molecular assemblies. Structure (2005) 2.12
Structure of the mammalian 80S ribosome at 8.7 A resolution. Structure (2008) 2.11
Refinement of protein structures by iterative comparative modeling and CryoEM density fitting. J Mol Biol (2006) 2.06
The role of human ribosomal proteins in the maturation of rRNA and ribosome production. RNA (2008) 1.81
The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast. EMBO J (2004) 1.77
Cells depleted for RPS19, a protein associated with Diamond Blackfan Anemia, show defects in 18S ribosomal RNA synthesis and small ribosomal subunit production. Blood Cells Mol Dis (2007) 1.68
Functional analysis of transcribed spacers of yeast ribosomal DNA. EMBO J (1990) 1.67
Structural characterization of components of protein assemblies by comparative modeling and electron cryo-microscopy. J Struct Biol (2005) 1.67
Direct link between RACK1 function and localization at the ribosome in vivo. Mol Cell Biol (2008) 1.61
RACK1 has the nerve to act: structure meets function in the nervous system. Prog Neurobiol (2006) 1.56
How well can the accuracy of comparative protein structure models be predicted? Protein Sci (2008) 1.52
Mutation of ribosomal protein RPS24 in Diamond-Blackfan anemia results in a ribosome biogenesis disorder. Hum Mol Genet (2008) 1.52
Structure of a signal transduction regulator, RACK1, from Arabidopsis thaliana. Protein Sci (2008) 1.52
A proposal for the secondary structure of a variable area of eukaryotic small ribosomal subunit RNA involving the existence of a pseudoknot. Nucleic Acids Res (1990) 1.42
Ribosomal protein P0, contrary to phosphoproteins P1 and P2, is required for ribosome activity and Saccharomyces cerevisiae viability. J Biol Chem (1994) 1.39
Interaction of the G' domain of elongation factor G and the C-terminal domain of ribosomal protein L7/L12 during translocation as revealed by cryo-EM. Mol Cell (2005) 1.38
Immunoelectron microscopic studies on the location of ribosomal proteins on the surface of the 40S ribosomal subunit from rat liver. Eur J Cell Biol (1990) 1.33
YUP: A Molecular Simulation Program for Coarse-Grained and Multi-Scaled Models. J Chem Theory Comput (2006) 1.27
Molecular basis of Diamond-Blackfan anemia: structure and function analysis of RPS19. Nucleic Acids Res (2007) 1.27
An rRNA variable region has an evolutionarily conserved essential role despite sequence divergence. Mol Cell Biol (1994) 1.23
Yeast ribosomal P0 protein has two separate binding sites for P1/P2 proteins. Mol Microbiol (2006) 1.22
Proteins P1, P2, and P0, components of the eukaryotic ribosome stalk. New structural and functional aspects. Biochem Cell Biol (1996) 1.13
Protein topography of the 40 S ribosomal subunit from rabbit reticulocytes shown by cross-linking with 2-iminothiolane. J Biol Chem (1981) 1.07
Fast 3D motif search of EM density maps using a locally normalized cross-correlation function. J Struct Biol (2003) 1.06
Structural relationships among the ribosomal stalk proteins from the three domains of life. J Mol Evol (2008) 1.04
Genetic evidence for 18S rRNA binding and an Rps19p assembly function of yeast nucleolar protein Nep1p. Mol Genet Genomics (2006) 1.02
Probing the secondary structure of expansion segment ES6 in 18S ribosomal RNA. Biochemistry (2006) 0.94
Characterization of interaction sites in the Saccharomyces cerevisiae ribosomal stalk components. Mol Microbiol (2002) 0.92
Localization of proteins S1, S2, S16 and S23 on the surface of small subunits of rat liver ribosomes by immune electron microscopy. Mol Gen Genet (1979) 0.92
A method for differentiating proteins from nucleic acids in intermediate-resolution density maps: cryo-electron microscopy defines the quaternary structure of the Escherichia coli 70S ribosome. Structure (2000) 0.89
Identification of neighboring protein pairs cross-linked with dimethyl 3,3'-dithiobispropionimidate in rat liver 40S ribosomal subunits. J Biochem (1981) 0.89
Comparison of fungal 80 S ribosomes by cryo-EM reveals diversity in structure and conformation of rRNA expansion segments. J Mol Biol (2007) 0.88
Role of different regions of ribosomal proteins L7 and L10 in their complex formation and in the interaction with the ribosomal 50 S subunit. FEBS Lett (1980) 0.88
A specific role for the phosphorylation of mammalian acidic ribosomal protein P2. J Biol Chem (1997) 0.87
Protein topography of the 40 S ribosomal subunit from Saccharomyces cerevisiae as shown by chemical cross-linking. J Biol Chem (1986) 0.84
Ribosomal proteins cross-linked to the initiator AUG codon of a mRNA in the translation initiation complex by UV-irradiation. J Biochem (2005) 0.83
Identification of neighbouring protein pairs in the rat liver 40-S ribosomal subunits cross-linked with dimethyl suberimidate. Biochim Biophys Acta (1980) 0.82
Solution structure of TA1092, a ribosomal protein S24e from Thermoplasma acidophilum. Proteins (2006) 0.79
Ribosomal proteins of Thermomyces lanuginosus--characterisation by two-dimensional gel electrophoresis and differential disassembly. Mol Cell Biochem (1995) 0.78