Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b.
|
Science
|
2010
|
2.73
|
2
|
Phenazine compounds in fluorescent Pseudomonas spp. biosynthesis and regulation.
|
Annu Rev Phytopathol
|
2006
|
2.31
|
3
|
Structures of the dual bromodomains of the P-TEFb-activating protein Brd4 at atomic resolution.
|
J Biol Chem
|
2009
|
1.96
|
4
|
RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity.
|
Mol Cell
|
2009
|
1.94
|
5
|
Novel correlations between the genotype and the phenotype of hypertrophic and dilated cardiomyopathy: results from the German Competence Network Heart Failure.
|
Eur J Heart Fail
|
2011
|
1.70
|
6
|
Insights into ssDNA recognition by the OB fold from a structural and thermodynamic study of Sulfolobus SSB protein.
|
EMBO J
|
2003
|
1.58
|
7
|
Diversity and evolution of the phenazine biosynthesis pathway.
|
Appl Environ Microbiol
|
2009
|
1.51
|
8
|
Analysis of the eukaryotic prenylome by isoprenoid affinity tagging.
|
Nat Chem Biol
|
2009
|
1.50
|
9
|
Of two make one: the biosynthesis of phenazines.
|
Chembiochem
|
2009
|
1.24
|
10
|
Noncompaction of the ventricular myocardium is associated with a de novo mutation in the beta-myosin heavy chain gene.
|
PLoS One
|
2007
|
1.15
|
11
|
High-affinity binding of phosphatidylinositol 4-phosphate by Legionella pneumophila DrrA.
|
EMBO Rep
|
2010
|
1.14
|
12
|
A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1.
|
EMBO J
|
2011
|
1.14
|
13
|
Breast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration.
|
Breast Cancer Res
|
2010
|
1.10
|
14
|
Adenylylation: renaissance of a forgotten post-translational modification.
|
Trends Biochem Sci
|
2011
|
1.09
|
15
|
Biophysical analysis of the interaction of Rab6a GTPase with its effector domains.
|
J Biol Chem
|
2008
|
1.05
|
16
|
PhzA/B catalyzes the formation of the tricycle in phenazine biosynthesis.
|
J Am Chem Soc
|
2008
|
1.04
|
17
|
Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation.
|
EMBO J
|
2008
|
0.97
|
18
|
Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef.
|
PLoS One
|
2011
|
0.94
|
19
|
Crystal structures of chloroperoxidase with its bound substrates and complexed with formate, acetate, and nitrate.
|
J Biol Chem
|
2006
|
0.94
|
20
|
Three novel mutations in the ACTA2 gene in German patients with thoracic aortic aneurysms and dissections.
|
Eur J Hum Genet
|
2011
|
0.94
|
21
|
Structure elucidation and preliminary assessment of hydrolase activity of PqsE, the Pseudomonas quinolone signal (PQS) response protein.
|
Biochemistry
|
2009
|
0.93
|
22
|
Psoromic acid is a selective and covalent Rab-prenylation inhibitor targeting autoinhibited RabGGTase.
|
J Am Chem Soc
|
2012
|
0.90
|
23
|
The active site of an enzyme can host both enantiomers of a racemic ligand simultaneously.
|
Angew Chem Int Ed Engl
|
2009
|
0.89
|
24
|
Recent insights into the diversity, frequency and ecological roles of phenazines in fluorescent Pseudomonas spp.
|
Environ Microbiol
|
2012
|
0.89
|
25
|
The structure of 3-methylaspartase from Clostridium tetanomorphum functions via the common enolase chemical step.
|
J Biol Chem
|
2001
|
0.87
|
26
|
High-resolution structures of RmlC from Streptococcus suis in complex with substrate analogs locate the active site of this class of enzyme.
|
Structure
|
2003
|
0.86
|
27
|
Development of selective, potent RabGGTase inhibitors.
|
J Med Chem
|
2012
|
0.85
|
28
|
The versatile Legionella effector protein DrrA.
|
Commun Integr Biol
|
2011
|
0.85
|
29
|
Ligand binding induces an ammonia channel in 2-amino-2-desoxyisochorismate (ADIC) synthase PhzE.
|
J Biol Chem
|
2011
|
0.85
|
30
|
Purification and crystallization of human Cu/Zn superoxide dismutase recombinantly produced in the protozoan Leishmania tarentolae.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.85
|
31
|
The purification, crystallization and preliminary structural characterization of PhzF, a key enzyme in the phenazine-biosynthesis pathway from Pseudomonas fluorescens 2-79.
|
Acta Crystallogr D Biol Crystallogr
|
2003
|
0.83
|
32
|
Crystallographic proof for an extended hydrogen-bonding network in small prolyl isomerases.
|
J Am Chem Soc
|
2011
|
0.81
|
33
|
Structure-guided development of selective RabGGTase inhibitors.
|
Angew Chem Int Ed Engl
|
2011
|
0.81
|
34
|
Trapped intermediates in crystals of the FMN-dependent oxidase PhzG provide insight into the final steps of phenazine biosynthesis.
|
Acta Crystallogr D Biol Crystallogr
|
2013
|
0.81
|
35
|
Design, synthesis, and characterization of peptide-based rab geranylgeranyl transferase inhibitors.
|
J Med Chem
|
2009
|
0.81
|
36
|
Structure of the sulfoxide synthase EgtB from the ergothioneine biosynthetic pathway.
|
Angew Chem Int Ed Engl
|
2015
|
0.80
|
37
|
Directed evolution of Mycobacterium tuberculosis β-lactamase reveals gatekeeper residue that regulates antibiotic resistance and catalytic efficiency.
|
PLoS One
|
2013
|
0.79
|
38
|
Revisiting the planarity of nucleic acid bases: Pyramidilization at glycosidic nitrogen in purine bases is modulated by orientation of glycosidic torsion.
|
Nucleic Acids Res
|
2009
|
0.79
|
39
|
Structure and dynamics of a stabilized coiled-coil domain in the P-TEFb regulator Hexim1.
|
J Mol Biol
|
2011
|
0.78
|
40
|
Ergothioneine biosynthetic methyltransferase EgtD reveals the structural basis of aromatic amino acid betaine biosynthesis.
|
Chembiochem
|
2014
|
0.78
|
41
|
Atomic resolution structure of EhpR: phenazine resistance in Enterobacter agglomerans Eh1087 follows principles of bleomycin/mitomycin C resistance in other bacteria.
|
BMC Struct Biol
|
2011
|
0.77
|
42
|
Structure of the corrinoid:coenzyme M methyltransferase MtaA from Methanosarcina mazei.
|
Acta Crystallogr D Biol Crystallogr
|
2012
|
0.77
|
43
|
Crystallization and preliminary crystal structure analysis of the ligand-binding domain of PqsR (MvfR), the Pseudomonas quinolone signal (PQS) responsive quorum-sensing transcription factor of Pseudomonas aeruginosa.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2012
|
0.77
|
44
|
Development of selective RabGGTase inhibitors and crystal structure of a RabGGTase-inhibitor complex.
|
Angew Chem Int Ed Engl
|
2008
|
0.76
|
45
|
The purification, crystallization and preliminary structural characterization of human MAWDBP, a member of the phenazine biosynthesis-like protein family.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2006
|
0.75
|
46
|
The purification, crystallization and preliminary structural characterization of PhzM, a phenazine-modifying methyltransferase from Pseudomonas aeruginosa.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2006
|
0.75
|
47
|
The purification, crystallization and preliminary structural characterization of FAD-dependent monooxygenase PhzS, a phenazine-modifying enzyme from Pseudomonas aeruginosa.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2006
|
0.75
|
48
|
Overexpression, purification and crystallization of PhzA, the first enzyme of the phenazine biosynthesis pathway of Pseudomonas fluorescens 2-79.
|
Acta Crystallogr D Biol Crystallogr
|
2004
|
0.75
|