Wulf Blankenfeldt

Author PubWeight™ 49.51‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b. Science 2010 2.73
2 Phenazine compounds in fluorescent Pseudomonas spp. biosynthesis and regulation. Annu Rev Phytopathol 2006 2.31
3 Structures of the dual bromodomains of the P-TEFb-activating protein Brd4 at atomic resolution. J Biol Chem 2009 1.96
4 RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity. Mol Cell 2009 1.94
5 Novel correlations between the genotype and the phenotype of hypertrophic and dilated cardiomyopathy: results from the German Competence Network Heart Failure. Eur J Heart Fail 2011 1.70
6 Insights into ssDNA recognition by the OB fold from a structural and thermodynamic study of Sulfolobus SSB protein. EMBO J 2003 1.58
7 Diversity and evolution of the phenazine biosynthesis pathway. Appl Environ Microbiol 2009 1.51
8 Analysis of the eukaryotic prenylome by isoprenoid affinity tagging. Nat Chem Biol 2009 1.50
9 Of two make one: the biosynthesis of phenazines. Chembiochem 2009 1.24
10 Noncompaction of the ventricular myocardium is associated with a de novo mutation in the beta-myosin heavy chain gene. PLoS One 2007 1.15
11 High-affinity binding of phosphatidylinositol 4-phosphate by Legionella pneumophila DrrA. EMBO Rep 2010 1.14
12 A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1. EMBO J 2011 1.14
13 Breast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration. Breast Cancer Res 2010 1.10
14 Adenylylation: renaissance of a forgotten post-translational modification. Trends Biochem Sci 2011 1.09
15 Biophysical analysis of the interaction of Rab6a GTPase with its effector domains. J Biol Chem 2008 1.05
16 PhzA/B catalyzes the formation of the tricycle in phenazine biosynthesis. J Am Chem Soc 2008 1.04
17 Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation. EMBO J 2008 0.97
18 Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef. PLoS One 2011 0.94
19 Crystal structures of chloroperoxidase with its bound substrates and complexed with formate, acetate, and nitrate. J Biol Chem 2006 0.94
20 Three novel mutations in the ACTA2 gene in German patients with thoracic aortic aneurysms and dissections. Eur J Hum Genet 2011 0.94
21 Structure elucidation and preliminary assessment of hydrolase activity of PqsE, the Pseudomonas quinolone signal (PQS) response protein. Biochemistry 2009 0.93
22 Psoromic acid is a selective and covalent Rab-prenylation inhibitor targeting autoinhibited RabGGTase. J Am Chem Soc 2012 0.90
23 The active site of an enzyme can host both enantiomers of a racemic ligand simultaneously. Angew Chem Int Ed Engl 2009 0.89
24 Recent insights into the diversity, frequency and ecological roles of phenazines in fluorescent Pseudomonas spp. Environ Microbiol 2012 0.89
25 The structure of 3-methylaspartase from Clostridium tetanomorphum functions via the common enolase chemical step. J Biol Chem 2001 0.87
26 High-resolution structures of RmlC from Streptococcus suis in complex with substrate analogs locate the active site of this class of enzyme. Structure 2003 0.86
27 Development of selective, potent RabGGTase inhibitors. J Med Chem 2012 0.85
28 The versatile Legionella effector protein DrrA. Commun Integr Biol 2011 0.85
29 Ligand binding induces an ammonia channel in 2-amino-2-desoxyisochorismate (ADIC) synthase PhzE. J Biol Chem 2011 0.85
30 Purification and crystallization of human Cu/Zn superoxide dismutase recombinantly produced in the protozoan Leishmania tarentolae. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 0.85
31 The purification, crystallization and preliminary structural characterization of PhzF, a key enzyme in the phenazine-biosynthesis pathway from Pseudomonas fluorescens 2-79. Acta Crystallogr D Biol Crystallogr 2003 0.83
32 Crystallographic proof for an extended hydrogen-bonding network in small prolyl isomerases. J Am Chem Soc 2011 0.81
33 Structure-guided development of selective RabGGTase inhibitors. Angew Chem Int Ed Engl 2011 0.81
34 Trapped intermediates in crystals of the FMN-dependent oxidase PhzG provide insight into the final steps of phenazine biosynthesis. Acta Crystallogr D Biol Crystallogr 2013 0.81
35 Design, synthesis, and characterization of peptide-based rab geranylgeranyl transferase inhibitors. J Med Chem 2009 0.81
36 Structure of the sulfoxide synthase EgtB from the ergothioneine biosynthetic pathway. Angew Chem Int Ed Engl 2015 0.80
37 Directed evolution of Mycobacterium tuberculosis β-lactamase reveals gatekeeper residue that regulates antibiotic resistance and catalytic efficiency. PLoS One 2013 0.79
38 Revisiting the planarity of nucleic acid bases: Pyramidilization at glycosidic nitrogen in purine bases is modulated by orientation of glycosidic torsion. Nucleic Acids Res 2009 0.79
39 Structure and dynamics of a stabilized coiled-coil domain in the P-TEFb regulator Hexim1. J Mol Biol 2011 0.78
40 Ergothioneine biosynthetic methyltransferase EgtD reveals the structural basis of aromatic amino acid betaine biosynthesis. Chembiochem 2014 0.78
41 Atomic resolution structure of EhpR: phenazine resistance in Enterobacter agglomerans Eh1087 follows principles of bleomycin/mitomycin C resistance in other bacteria. BMC Struct Biol 2011 0.77
42 Structure of the corrinoid:coenzyme M methyltransferase MtaA from Methanosarcina mazei. Acta Crystallogr D Biol Crystallogr 2012 0.77
43 Crystallization and preliminary crystal structure analysis of the ligand-binding domain of PqsR (MvfR), the Pseudomonas quinolone signal (PQS) responsive quorum-sensing transcription factor of Pseudomonas aeruginosa. Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 0.77
44 Development of selective RabGGTase inhibitors and crystal structure of a RabGGTase-inhibitor complex. Angew Chem Int Ed Engl 2008 0.76
45 The purification, crystallization and preliminary structural characterization of human MAWDBP, a member of the phenazine biosynthesis-like protein family. Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 0.75
46 The purification, crystallization and preliminary structural characterization of PhzM, a phenazine-modifying methyltransferase from Pseudomonas aeruginosa. Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 0.75
47 The purification, crystallization and preliminary structural characterization of FAD-dependent monooxygenase PhzS, a phenazine-modifying enzyme from Pseudomonas aeruginosa. Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 0.75
48 Overexpression, purification and crystallization of PhzA, the first enzyme of the phenazine biosynthesis pathway of Pseudomonas fluorescens 2-79. Acta Crystallogr D Biol Crystallogr 2004 0.75