Gaetano Cairo

Author PubWeight™ 40.52‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev 2004 9.28
2 Alterations of systemic and muscle iron metabolism in human subjects treated with low-dose recombinant erythropoietin. Blood 2009 1.66
3 Differential regulation of iron homeostasis during human macrophage polarized activation. Eur J Immunol 2010 1.64
4 Iron regulatory proteins 1 and 2 in human monocytes, macrophages and duodenum: expression and regulation in hereditary hemochromatosis and iron deficiency. Haematologica 2006 1.51
5 Iron regulatory proteins: from molecular mechanisms to drug development. Antioxid Redox Signal 2010 1.35
6 New functions for an iron storage protein: the role of ferritin in immunity and autoimmunity. J Autoimmun 2008 1.21
7 Adenosine A2a receptor-mediated, normoxic induction of HIF-1 through PKC and PI-3K-dependent pathways in macrophages. J Leukoc Biol 2007 1.16
8 Iron depletion by deferoxamine up-regulates glucose uptake and insulin signaling in hepatoma cells and in rat liver. Am J Pathol 2008 1.14
9 Role of HIF-1 and NF-kappaB transcription factors in the modulation of transferrin receptor by inflammatory and anti-inflammatory signals. J Biol Chem 2008 1.13
10 Doxorubicin cardiotoxicity and the control of iron metabolism: quinone-dependent and independent mechanisms. Methods Enzymol 2004 1.12
11 Kupffer cells and macrophages are not required for hepatic hepcidin activation during iron overload. Hepatology 2005 1.06
12 An introduction to the metabolic determinants of anthracycline cardiotoxicity. Cardiovasc Toxicol 2007 1.00
13 Doxorubicin paradoxically protects cardiomyocytes against iron-mediated toxicity: role of reactive oxygen species and ferritin. J Biol Chem 2004 0.98
14 Iron levels in polarized macrophages: regulation of immunity and autoimmunity. Autoimmun Rev 2012 0.96
15 Dietary iron overload induces visceral adipose tissue insulin resistance. Am J Pathol 2013 0.96
16 Strong iron demand during hypoxia-induced erythropoiesis is associated with down-regulation of iron-related proteins and myoglobin in human skeletal muscle. Blood 2007 0.93
17 Transferrin receptor gene expression and transferrin-bound iron uptake are increased during postischemic rat liver reperfusion. Hepatology 2002 0.91
18 Reactive oxygen species-independent apoptosis in doxorubicin-treated H9c2 cardiomyocytes: role for heme oxygenase-1 down-modulation. Chem Biol Interact 2008 0.90
19 Oxidative stress-mediated down-regulation of rat hydroxyacid oxidase 1, a liver-specific peroxisomal enzyme. Hepatology 2003 0.89
20 Adenosine-dependent activation of hypoxia-inducible factor-1 induces late preconditioning in liver cells. Hepatology 2008 0.89
21 Iron-dependent regulation of MDM2 influences p53 activity and hepatic carcinogenesis. Am J Pathol 2009 0.88
22 Liver iron modulates hepcidin expression during chronically elevated erythropoiesis in mice. Hepatology 2013 0.87
23 Macrophages: central regulators of iron balance. Metallomics 2014 0.84
24 Mice lacking mitochondrial ferritin are more sensitive to doxorubicin-mediated cardiotoxicity. J Mol Med (Berl) 2014 0.84
25 Blotting analysis of native IRP1: a novel approach to distinguish the different forms of IRP1 in cells and tissues. Biochemistry 2004 0.84
26 Loss of the von Hippel Lindau tumor suppressor disrupts iron homeostasis in renal carcinoma cells. J Biol Chem 2005 0.84
27 Serum hepcidin levels and muscle iron proteins in humans injected with low- or high-dose erythropoietin. Eur J Haematol 2013 0.83
28 IRP1-independent alterations of cardiac iron metabolism in doxorubicin-treated mice. J Mol Med (Berl) 2006 0.82
29 Recent Advances in Iron Metabolism: Relevance for Health, Exercise, and Performance. Med Sci Sports Exerc 2015 0.81
30 Up regulation of IL-6 by ischemic preconditioning in normal and fatty rat livers: association with reduction of oxidative stress. Free Radic Res 2006 0.80
31 Setup for human sera MALDI profiling: the case of rhEPO treatment. Electrophoresis 2011 0.79
32 Adenosine A(2)A receptor but not HIF-1 mediates Tyrosine hydroxylase induction in hypoxic PC12 cells. J Neurosci Res 2010 0.77
33 Potent trophic activity of spermidine supramolecular complexes in in vitro models. World J Biol Chem 2013 0.76
34 The transferrin receptor: the cellular iron gate. Metallomics 2017 0.75