Sex differences in molecular neuroscience: from fruit flies to humans.

PubWeight™: 2.17‹?› | Rank: Top 2%

🔗 View Article (PMID 20019686)

Published in Nat Rev Neurosci on January 01, 2010

Authors

Elena Jazin1, Larry Cahill

Author Affiliations

1: Department of Genetics and Development, Evolutionary Biology Centre, Uppsala University, SE-75236, Sweden. elena.jazin@ebc.uu.se

Associated clinical trials:

A Longitudinal Investigation of the Endocrine and Neurobiologic Events Accompanying Puberty | NCT01434368

Articles citing this

Sex differences in the structural connectome of the human brain. Proc Natl Acad Sci U S A (2013) 3.06

Reframing sexual differentiation of the brain. Nat Neurosci (2011) 2.49

Sexually dimorphic neurons in the ventromedial hypothalamus govern mating in both sexes and aggression in males. Cell (2013) 2.41

Sex differences in the brain: the not so inconvenient truth. J Neurosci (2012) 1.83

Sex differences in pain and pain inhibition: multiple explanations of a controversial phenomenon. Nat Rev Neurosci (2012) 1.80

Neuroprotection mediated through estrogen receptor-alpha in astrocytes. Proc Natl Acad Sci U S A (2011) 1.68

Genes that escape from X inactivation. Hum Genet (2011) 1.63

A half-truth is a whole lie: on the necessity of investigating sex influences on the brain. Endocrinology (2012) 1.42

Identification of differentially expressed microRNAs across the developing human brain. Mol Psychiatry (2013) 1.30

Resting functional connectivity of language networks: characterization and reproducibility. Mol Psychiatry (2012) 1.29

Female-biased expression of long non-coding RNAs in domains that escape X-inactivation in mouse. BMC Genomics (2010) 1.19

Widespread sex differences in gene expression and splicing in the adult human brain. Nat Commun (2013) 1.15

Dissociation of genetic and hormonal influences on sex differences in alcoholism-related behaviors. J Neurosci (2010) 1.12

Accounting for eXentricities: analysis of the X chromosome in GWAS reveals X-linked genes implicated in autoimmune diseases. PLoS One (2014) 1.04

Sexual differentiation and development of forebrain reproductive circuits. Curr Opin Neurobiol (2010) 1.03

Sex-dependent cognitive performance in baboon offspring following maternal caloric restriction in pregnancy and lactation. Reprod Sci (2012) 0.98

Fundamental sex difference in human brain architecture. Proc Natl Acad Sci U S A (2013) 0.95

A human-mouse conserved sex bias in amygdala gene expression related to circadian clock and energy metabolism. Mol Brain (2011) 0.94

Expression profiling associates blood and brain glucocorticoid receptor signaling with trauma-related individual differences in both sexes. Proc Natl Acad Sci U S A (2014) 0.94

Sex differences in the cerebellum and frontal cortex: roles of estrogen receptor alpha and sex chromosome genes. Neuroendocrinology (2011) 0.93

Gender affects body language reading. Front Psychol (2011) 0.93

Same sex, no sex, and unaware sex in neurotoxicology. Neurotoxicology (2010) 0.90

Neurological symptoms in individuals with fibrodysplasia ossificans progressiva. J Neurol (2012) 0.89

The influence of sex-linked genetic mechanisms on attention and impulsivity. Biol Psychol (2011) 0.88

Incorporating Sex as a Variable in Preclinical Neuropsychiatric Research. Schizophr Bull (2015) 0.88

Equal ≠ the same: sex differences in the human brain. Cerebrum (2014) 0.86

Isoaspartyl formation in creatine kinase B is associated with loss of enzymatic activity; implications for the linkage of isoaspartate accumulation and neurological dysfunction in the PIMT knockout mouse. PLoS One (2014) 0.85

Multivariate neuroanatomical classification of cognitive subtypes in schizophrenia: a support vector machine learning approach. Neuroimage Clin (2014) 0.84

Limited sex-biased neural gene expression patterns across strains in Zebrafish (Danio rerio). BMC Genomics (2014) 0.83

2014 Thomas Willis Award Lecture: sex, stroke, and innovation. Stroke (2014) 0.83

Elevated expression of H19 and Igf2 in the female mouse eye. PLoS One (2013) 0.82

Identification of sexually dimorphic genes in the neonatal mouse cortex and hippocampus. Brain Res (2014) 0.82

A single nucleotide polymorphism in the coding region of PGC-1α is a male-specific modifier of Huntington disease age-at-onset in a large European cohort. BMC Neurol (2014) 0.81

Regulation of estrogen receptor alpha gene expression in the mouse prefrontal cortex during early postnatal development. Neurogenetics (2012) 0.81

Pre- and/or postnatal protein restriction in rats impairs learning and motivation in male offspring. Int J Dev Neurosci (2010) 0.81

The parent-of-origin of the extra X chromosome may differentially affect psychopathology in Klinefelter syndrome. Biol Psychiatry (2010) 0.80

Cardiovascular fitness is associated with altered cortical glucose metabolism during working memory in ɛ4 carriers. Alzheimers Dement (2012) 0.80

Sexual divergence in microtubule function: the novel intranasal microtubule targeting SKIP normalizes axonal transport and enhances memory. Mol Psychiatry (2016) 0.78

Large-scale transcriptome sequencing reveals novel expression patterns for key sex-related genes in a sex-changing fish. Biol Sex Differ (2015) 0.78

Sex and the Lab: An Alcohol-Focused Commentary on the NIH Initiative to Balance Sex in Cell and Animal Studies. Alcohol Clin Exp Res (2016) 0.78

Sex Biased Gene Expression Profiling of Human Brains at Major Developmental Stages. Sci Rep (2016) 0.78

Estrogen Receptor β Activation Rapidly Modulates Male Sexual Motivation through the Transactivation of Metabotropic Glutamate Receptor 1a. J Neurosci (2015) 0.78

Sex differences in protein expression in the mouse brain and their perturbations in a model of Down syndrome. Biol Sex Differ (2015) 0.78

Affective recognition memory processing and event-related brain potentials. Cogn Affect Behav Neurosci (2011) 0.78

Isoaspartate accumulation in mouse brain is associated with altered patterns of protein phosphorylation and acetylation, some of which are highly sex-dependent. PLoS One (2013) 0.78

The anatomical problem posed by brain complexity and size: a potential solution. Front Neuroanat (2015) 0.77

Examining the sex- and circadian dependency of a learning phenotype in mice with glycine transporter 1 deletion in two Pavlovian conditioning paradigms. Neurobiol Learn Mem (2011) 0.77

Sex stratified neuronal cultures to study ischemic cell death pathways. J Vis Exp (2013) 0.77

Microarray analysis reveals higher gestational folic Acid alters expression of genes in the cerebellum of mice offspring-a pilot study. Brain Sci (2015) 0.77

Developmental neurogenetics and multimodal neuroimaging of sex differences in autism. Brain Imaging Behav (2016) 0.77

Sex differences in partner preferences in humans and animals. Philos Trans R Soc Lond B Biol Sci (2016) 0.76

Sexual dimorphism in expression of insulin and insulin-like growth factor-I receptors in developing rat cerebellum. Cell Mol Neurobiol (2013) 0.76

Bisphenol A Interaction With Brain Development and Functions. Dose Response (2015) 0.76

Maternal stress has divergent effects on gene expression patterns in the brains of male and female threespine stickleback. Proc Biol Sci (2016) 0.76

High Throughput Sequencing Identifies Misregulated Genes in the Drosophila Polypyrimidine Tract-Binding Protein (hephaestus) Mutant Defective in Spermatogenesis. PLoS One (2016) 0.75

Brain Transcriptional Profiles of Male Alternative Reproductive Tactics and Females in Bluegill Sunfish. PLoS One (2016) 0.75

Spatial sexual dimorphism of X and Y homolog gene expression in the human central nervous system during early male development. Biol Sex Differ (2016) 0.75

Neural development: A fruitless sexual switch. Nat Rev Neurosci (2012) 0.75

Sex disparities in substance abuse research: Evaluating 23 years of structural neuroimaging studies. Drug Alcohol Depend (2017) 0.75

Articles by these authors

Pilot study of secondary prevention of posttraumatic stress disorder with propranolol. Biol Psychiatry (2002) 3.15

Sex influences on the neurobiology of learning and memory. Learn Mem (2009) 2.10

Amygdala modulation of parahippocampal and frontal regions during emotionally influenced memory storage. Neuroimage (2003) 1.67

Glucocorticoid release and memory consolidation in men and women. Psychol Sci (2006) 1.47

A case of unusual autobiographical remembering. Neurocase (2006) 1.37

Menstrual cycle modulation of medial temporal activity evoked by negative emotion. Neuroimage (2010) 1.34

Menstrual cycle modulation of the relationship between cortisol and long-term memory. Psychoneuroendocrinology (2008) 1.27

Neuroimaging analysis of an anesthetic gas that blocks human emotional memory. Proc Natl Acad Sci U S A (2008) 1.21

Relationship of enhanced norepinephrine activity during memory consolidation to enhanced long-term memory in humans. Am J Psychiatry (2002) 1.18

Hormonal contraception usage is associated with altered memory for an emotional story. Neurobiol Learn Mem (2011) 1.11

Endogenous noradrenergic activation and memory for emotional material in men and women. Psychoneuroendocrinology (2009) 1.03

Behavioral and neuroanatomical investigation of Highly Superior Autobiographical Memory (HSAM). Neurobiol Learn Mem (2012) 1.01

Influences of menstrual cycle position and sex hormone levels on spontaneous intrusive recollections following emotional stimuli. Conscious Cogn (2011) 1.00

Children's and adults' salivary cortisol responses to an identical psychosocial laboratory stressor. Psychoneuroendocrinology (2009) 0.98

Differential effects of emotional arousal in short- and long-term memory in healthy adults. Neurobiol Learn Mem (2003) 0.97

Post-event spontaneous intrusive recollections and strength of memory for emotional events in men and women. Conscious Cogn (2009) 0.92

Modulation of memory consolidation for olfactory learning by reversible inactivation of the basolateral amygdala. Behav Neurosci (2003) 0.92

Hormonal contraception use alters stress responses and emotional memory. Biol Psychol (2012) 0.90

Progesterone at encoding predicts subsequent emotional memory. Learn Mem (2011) 0.88

Sex and menstrual cycle phase at encoding influence emotional memory for gist and detail. Neurobiol Learn Mem (2013) 0.87

Propranolol for reemergent posttraumatic stress disorder following an event of retraumatization: a case study. J Trauma Stress (2002) 0.86

The lowdown on Ginkgo biloba. Sci Am (2003) 0.86

Equal ≠ the same: sex differences in the human brain. Cerebrum (2014) 0.86

Sex-related hemispheric lateralization of electrical potentials evoked by arousing negative stimuli. Brain Res (2006) 0.85

Effects of breast cancer treatment on the hormonal and cognitive consequences of acute stress. Psychooncology (2011) 0.83

The role of cortisol reactivity in children's and adults' memory of a prior stressful experience. Dev Psychobiol (2010) 0.81

The influence of emergency contraception on post-traumatic stress symptoms following sexual assault. J Forensic Nurs (2012) 0.81

Oversimplifying sex differences in the brain: man and woman: an inside story. Cerebrum (2011) 0.75