Published in PLoS Genet on December 18, 2009
Annotation of functional variation in personal genomes using RegulomeDB. Genome Res (2012) 11.47
Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo. EMBO J (2010) 4.78
Human RNA polymerase III transcriptomes and relationships to Pol II promoter chromatin and enhancer-binding factors. Nat Struct Mol Biol (2010) 2.30
Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells. Proc Natl Acad Sci U S A (2011) 2.16
ChIPBase: a database for decoding the transcriptional regulation of long non-coding RNA and microRNA genes from ChIP-Seq data. Nucleic Acids Res (2012) 2.11
Genomic regions flanking E-box binding sites influence DNA binding specificity of bHLH transcription factors through DNA shape. Cell Rep (2013) 2.03
Rapid evolutionary rewiring of a structurally constrained eye enhancer. Curr Biol (2011) 1.98
An integrated ChIP-seq analysis platform with customizable workflows. BMC Bioinformatics (2011) 1.92
Reduced dosage of ERF causes complex craniosynostosis in humans and mice and links ERK1/2 signaling to regulation of osteogenesis. Nat Genet (2013) 1.87
Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages. EMBO J (2010) 1.82
Oncogenic ETS proteins mimic activated RAS/MAPK signaling in prostate cells. Genes Dev (2011) 1.56
Mutant p53 cooperates with ETS2 to promote etoposide resistance. Genes Dev (2012) 1.47
Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia. Cancer Cell (2012) 1.43
Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm. EMBO J (2013) 1.35
Genome-wide analysis reveals PADI4 cooperates with Elk-1 to activate c-Fos expression in breast cancer cells. PLoS Genet (2011) 1.33
Tumor-specific retargeting of an oncogenic transcription factor chimera results in dysregulation of chromatin and transcription. Genome Res (2011) 1.29
Large-scale quality analysis of published ChIP-seq data. G3 (Bethesda) (2014) 1.23
Gene deregulation and chronic activation in natural killer cells deficient in the transcription factor ETS1. Immunity (2012) 1.18
Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactyly. Dev Cell (2012) 1.16
ERG cooperates with androgen receptor in regulating trefoil factor 3 in prostate cancer disease progression. Neoplasia (2010) 1.14
DNA binding by the ETS protein TEL (ETV6) is regulated by autoinhibition and self-association. J Biol Chem (2010) 1.13
ELK1 uses different DNA binding modes to regulate functionally distinct classes of target genes. PLoS Genet (2012) 1.11
Deciphering the Sox-Oct partner code by quantitative cooperativity measurements. Nucleic Acids Res (2012) 1.11
Genome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion. Nucleic Acids Res (2011) 1.11
Molecular mechanisms of ETS transcription factor-mediated tumorigenesis. Crit Rev Biochem Mol Biol (2013) 1.08
ETS1 mediates MEK1/2-dependent overexpression of cancerous inhibitor of protein phosphatase 2A (CIP2A) in human cancer cells. PLoS One (2011) 1.05
Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma. Genes Cancer (2010) 0.98
Comprehensive prediction in 78 human cell lines reveals rigidity and compactness of transcription factor dimers. Genome Res (2013) 0.97
The forkhead transcription factor FOXK2 promotes AP-1-mediated transcriptional regulation. Mol Cell Biol (2011) 0.96
The ETS transcription factors ELK1 and GABPA regulate different gene networks to control MCF10A breast epithelial cell migration. PLoS One (2012) 0.96
Genome-wide binding map of the HIV-1 Tat protein to the human genome. PLoS One (2011) 0.95
Lessons on transcriptional control from the serum response network. Curr Opin Genet Dev (2011) 0.92
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells. Nucleic Acids Res (2014) 0.92
Chromosome I controls chromosome II replication in Vibrio cholerae. PLoS Genet (2014) 0.91
Sequence discrimination by DNA-binding domain of ETS family transcription factor PU.1 is linked to specific hydration of protein-DNA interface. J Biol Chem (2012) 0.91
Prostate cancer ETS rearrangements switch a cell migration gene expression program from RAS/ERK to PI3K/AKT regulation. Mol Cancer (2014) 0.90
The transcriptional programme controlled by Runx1 during early embryonic blood development. Dev Biol (2012) 0.90
Genomic analysis reveals a novel nuclear factor-κB (NF-κB)-binding site in Alu-repetitive elements. J Biol Chem (2011) 0.90
Genome-wide promoter analysis of histone modifications in human monocyte-derived antigen presenting cells. BMC Genomics (2010) 0.89
PhysBinder: Improving the prediction of transcription factor binding sites by flexible inclusion of biophysical properties. Nucleic Acids Res (2013) 0.89
Inducible chromatin priming is associated with the establishment of immunological memory in T cells. EMBO J (2016) 0.87
Structure-aided prediction of mammalian transcription factor complexes in conserved non-coding elements. Philos Trans R Soc Lond B Biol Sci (2013) 0.87
Identification of a core miRNA-pathway regulatory network in glioma by therapeutically targeting miR-181d, miR-21, miR-23b, β-Catenin, CBP, and STAT3. PLoS One (2014) 0.87
The possible functions of duplicated ets (GGAA) motifs located near transcription start sites of various human genes. Cell Mol Life Sci (2011) 0.86
TACO: a general-purpose tool for predicting cell-type-specific transcription factor dimers. BMC Genomics (2014) 0.85
ETS-4 is a transcriptional regulator of life span in Caenorhabditis elegans. PLoS Genet (2010) 0.85
The B cell transcription program mediates hypomethylation and overexpression of key genes in Epstein-Barr virus-associated proliferative conversion. Genome Biol (2013) 0.85
Spi-1/PU.1 activates transcription through clustered DNA occupancy in erythroleukemia. Nucleic Acids Res (2012) 0.85
Finding subtypes of transcription factor motif pairs with distinct regulatory roles. Nucleic Acids Res (2011) 0.85
RAS/ERK pathway transcriptional regulation through ETS/AP-1 binding sites. Small GTPases (2012) 0.85
ETS1 regulates the expression of ATXN2. Hum Mol Genet (2012) 0.84
HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells. Elife (2015) 0.84
Bayesian hierarchical model of protein-binding microarray k-mer data reduces noise and identifies transcription factor subclasses and preferred k-mers. Bioinformatics (2013) 0.84
Heterogeneous dynamics in DNA site discrimination by the structurally homologous DNA-binding domains of ETS-family transcription factors. Nucleic Acids Res (2015) 0.84
Structures of the Ets Protein DNA-binding Domains of Transcription Factors Etv1, Etv4, Etv5, and Fev: DETERMINANTS OF DNA BINDING AND REDOX REGULATION BY DISULFIDE BOND FORMATION. J Biol Chem (2015) 0.83
Hmga2 is a direct target gene of RUNX1 and regulates expansion of myeloid progenitors in mice. Blood (2014) 0.82
Multiple ETS family proteins regulate PF4 gene expression by binding to the same ETS binding site. PLoS One (2011) 0.82
Regulation of early T-lineage gene expression and developmental progression by the progenitor cell transcription factor PU.1. Genes Dev (2015) 0.82
Coordinate transcriptional regulation by ERG and androgen receptor in fusion-positive prostate cancers. Cancer Cell (2010) 0.81
Distinct Activities of Myf5 and MyoD Indicate Separate Roles in Skeletal Muscle Lineage Specification and Differentiation. Dev Cell (2016) 0.81
Dynamic recruitment of Ets1 to both nucleosome-occupied and -depleted enhancer regions mediates a transcriptional program switch during early T-cell differentiation. Nucleic Acids Res (2015) 0.80
Recent advances in the structural molecular biology of Ets transcription factors: interactions, interfaces and inhibition. Biochem Soc Trans (2014) 0.80
Differential transcription factor use by the KIR2DL4 promoter under constitutive and IL-2/15-treated conditions. J Immunol (2012) 0.80
Cistrome plasticity and mechanisms of cistrome reprogramming. Cell Cycle (2012) 0.80
Extracellular signal-regulated kinase signaling regulates the opposing roles of JUN family transcription factors at ETS/AP-1 sites and in cell migration. Mol Cell Biol (2014) 0.79
Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circ Cardiovasc Genet (2014) 0.79
Synthetic Bax-Anti Bcl2 combination module actuated by super artificial hTERT promoter selectively inhibits malignant phenotypes of bladder cancer. J Exp Clin Cancer Res (2016) 0.79
Epigenetic mechanisms and developmental choice hierarchies in T-lymphocyte development. Brief Funct Genomics (2013) 0.78
Genome-wide repression of eRNA and target gene loci by the ETV6-RUNX1 fusion in acute leukemia. Genome Res (2016) 0.77
The ETS family member GABPα modulates androgen receptor signalling and mediates an aggressive phenotype in prostate cancer. Nucleic Acids Res (2014) 0.77
Genome-wide binding studies reveal DNA binding specificity mechanisms and functional interplay amongst Forkhead transcription factors. Nucleic Acids Res (2015) 0.77
Structural basis of Ets1 activation by Runx1. Leukemia (2014) 0.77
Distinct Roles for Interfacial Hydration in Site-Specific DNA Recognition by ETS-Family Transcription Factors. J Phys Chem B (2017) 0.77
Cooperative binding of AP-1 and TEAD4 modulates the balance between vascular smooth muscle and hemogenic cell fate. Development (2016) 0.75
RUNX3 facilitates growth of Ewing sarcoma cells. J Cell Physiol (2014) 0.75
Contribution of transcription factor binding site motif variants to condition-specific gene expression patterns in budding yeast. PLoS One (2012) 0.75
GABPα Binding to Overlapping ETS and CRE DNA Motifs Is Enhanced by CREB1: Custom DNA Microarrays. G3 (Bethesda) (2015) 0.75
Important biological information uncovered in previously unaligned reads from chromatin immunoprecipitation experiments (ChIP-Seq). Sci Rep (2015) 0.75
Genome-scale technology driven advances to research into normal and malignant haematopoiesis. Scientifica (Cairo) (2012) 0.75
The role of Pbx1 in T cells. Protein Cell (2011) 0.75
FARE-CAFE: a database of functional and regulatory elements of cancer-associated fusion events. Database (Oxford) (2015) 0.75
STEME: a robust, accurate motif finder for large data sets. PLoS One (2014) 0.75
Genome-Wide Identification of Target Genes for the Key B Cell Transcription Factor Ets1. Front Immunol (2017) 0.75
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2. Nucleic Acids Res (2017) 0.75
Polymorphisms in Genes Involved in EGFR Turnover Are Predictive for Cetuximab Efficacy in Colorectal Cancer. Mol Cancer Ther (2015) 0.75
Most of the tight positional conservation of transcription factor binding sites near the transcription start site reflects their co-localization within regulatory modules. BMC Bioinformatics (2016) 0.75
Inhibiting cell migration and cell invasion by silencing the transcription factor ETS-1 in human bladder cancer. Oncotarget (2016) 0.75
Direct ChIP-Seq significance analysis improves target prediction. BMC Genomics (2015) 0.75
Proteasome system dysregulation and treatment resistance mechanisms in major depressive disorder. Transl Psychiatry (2015) 0.75
The two sides of Tat. Elife (2016) 0.75
Activation of Mouse Tcrb: Uncoupling RUNX1 Function from Its Cooperative Binding with ETS1. J Immunol (2017) 0.75
High-resolution profiling of histone methylations in the human genome. Cell (2007) 85.74
Fitting a mixture model by expectation maximization to discover motifs in biopolymers. Proc Int Conf Intell Syst Mol Biol (1994) 37.96
DNA methylation patterns and epigenetic memory. Genes Dev (2002) 33.83
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat Genet (2007) 32.41
Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature (2008) 30.29
Large-scale analysis of the human and mouse transcriptomes. Proc Natl Acad Sci U S A (2002) 25.47
GoMiner: a resource for biological interpretation of genomic and proteomic data. Genome Biol (2003) 22.63
ChIP-seq accurately predicts tissue-specific activity of enhancers. Nature (2009) 18.38
High-resolution mapping and characterization of open chromatin across the genome. Cell (2008) 15.93
Identifying DNA and protein patterns with statistically significant alignments of multiple sequences. Bioinformatics (1999) 14.36
Genome-wide analysis of transcription factor binding sites based on ChIP-Seq data. Nat Methods (2008) 11.61
Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes. Cell (2009) 8.69
Nucleosome positioning and gene regulation: advances through genomics. Nat Rev Genet (2009) 6.50
The ETS-domain transcription factor family. Nat Rev Mol Cell Biol (2001) 6.01
One nucleotide in a kappaB site can determine cofactor specificity for NF-kappaB dimers. Cell (2004) 4.53
DNA binding site sequence directs glucocorticoid receptor structure and activity. Science (2009) 4.48
Molecular biology of the Ets family of transcription factors. Gene (2003) 4.41
Empirical methods for controlling false positives and estimating confidence in ChIP-Seq peaks. BMC Bioinformatics (2008) 4.41
Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions. Genes Dev (1995) 4.34
Regulation of organogenesis by the Caenorhabditis elegans FoxA protein PHA-4. Science (2002) 4.33
Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding. Genome Res (2008) 4.11
Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family. Genes Dev (2007) 3.56
Telomerase maintains telomere structure in normal human cells. Cell (2003) 3.29
Chromatin decouples promoter threshold from dynamic range. Nature (2008) 3.24
Genetic evidence supporting selection of the Valpha14i NKT cell lineage from double-positive thymocyte precursors. Immunity (2005) 2.72
A mechanism for coordinating chromatin modification and preinitiation complex assembly. Mol Cell (2006) 2.69
The Ets-1 transcription factor is required for the development of natural killer cells in mice. Immunity (1998) 2.68
Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors. Cell (2008) 2.60
ERM is required for transcriptional control of the spermatogonial stem cell niche. Nature (2005) 2.58
Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors. Nucleic Acids Res (2004) 2.55
Defective activation and survival of T cells lacking the Ets-1 transcription factor. Nature (1995) 2.46
Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene. Nature (1995) 2.33
Cooperative binding of Ets-1 and core binding factor to DNA. Mol Cell Biol (1994) 2.27
Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation. EMBO J (1998) 2.09
E2F in vivo binding specificity: comparison of consensus versus nonconsensus binding sites. Genome Res (2008) 2.07
A role for CREB binding protein and p300 transcriptional coactivators in Ets-1 transactivation functions. Mol Cell Biol (1998) 1.93
Ras/mitogen-activated protein kinase signaling activates Ets-1 and Ets-2 by CBP/p300 recruitment. Mol Cell Biol (2004) 1.89
Transactivation of the Moloney murine leukemia virus and T-cell receptor beta-chain enhancers by cbf and ets requires intact binding sites for both proteins. J Virol (1995) 1.80
Changes in the expression of many Ets family transcription factors and of potential target genes in normal mammary tissue and tumors. J Biol Chem (2003) 1.72
Core binding factors are necessary for natural killer cell development and cooperate with Notch signaling during T-cell specification. Blood (2008) 1.67
A comparative analysis of genome-wide chromatin immunoprecipitation data for mammalian transcription factors. Nucleic Acids Res (2006) 1.67
Auto-inhibition of Ets-1 is counteracted by DNA binding cooperativity with core-binding factor alpha2. Mol Cell Biol (2000) 1.62
ChIPping away at gene regulation. EMBO Rep (2008) 1.54
Mechanism of action of a distal NF-kappaB-dependent enhancer. Mol Cell Biol (2006) 1.53
p300/cAMP-responsive element-binding protein interactions with ets-1 and ets-2 in the transcriptional activation of the human stromelysin promoter. J Biol Chem (1999) 1.34
Activation of the granulocyte-macrophage colony-stimulating factor promoter in T cells requires cooperative binding of Elf-1 and AP-1 transcription factors. Mol Cell Biol (1994) 1.28
All and only CpG containing sequences are enriched in promoters abundantly bound by RNA polymerase II in multiple tissues. BMC Genomics (2008) 1.28
CpG methylation has differential effects on the binding of YY1 and ETS proteins to the bi-directional promoter of the Surf-1 and Surf-2 genes. Nucleic Acids Res (1995) 1.18
A DNA methylation site in the male-specific P450 (Cyp 2d-9) promoter and binding of the heteromeric transcription factor GABP. Mol Cell Biol (1995) 1.17
A single amino-acid substitution in the Ets domain alters core DNA binding specificity of Ets1 to that of the related transcription factors Elf1 and E74. Nucleic Acids Res (1993) 1.07
Runx proteins are involved in regulation of CD122, Ly49 family and IFN-gamma expression during NK cell differentiation. Int Immunol (2007) 1.05
GA-binding protein and p300 are essential components of a retinoic acid-induced enhanceosome in myeloid cells. Mol Cell Biol (2006) 0.92
Tackling the widespread and critical impact of batch effects in high-throughput data. Nat Rev Genet (2010) 11.82
Model-based analysis of two-color arrays (MA2C). Genome Biol (2007) 7.28
Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter. Nature (2009) 5.34
The sva package for removing batch effects and other unwanted variation in high-throughput experiments. Bioinformatics (2012) 4.48
Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo. Immunity (2002) 4.15
Of lineage and legacy: the development of mammalian hematopoietic stem cells. Nat Immunol (2008) 4.04
Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family. Genes Dev (2007) 3.56
Using VAAST to identify an X-linked disorder resulting in lethality in male infants due to N-terminal acetyltransferase deficiency. Am J Hum Genet (2011) 3.43
Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype. Blood (2005) 3.32
Genomic and biochemical insights into the specificity of ETS transcription factors. Annu Rev Biochem (2011) 2.89
Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors. Nucleic Acids Res (2004) 2.55
Variable control of Ets-1 DNA binding by multiple phosphates in an unstructured region. Science (2005) 2.47
Autoinhibitory domains: modular effectors of cellular regulation. Annu Rev Cell Dev Biol (2002) 2.44
Human RNA polymerase III transcriptomes and relationships to Pol II promoter chromatin and enhancer-binding factors. Nat Struct Mol Biol (2010) 2.30
PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis. Nat Genet (2007) 2.18
The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity. Cancer Cell (2006) 2.09
Microsatellites as EWS/FLI response elements in Ewing's sarcoma. Proc Natl Acad Sci U S A (2008) 2.06
Core-binding factors in hematopoiesis and immune function. Oncogene (2004) 2.04
Ras/mitogen-activated protein kinase signaling activates Ets-1 and Ets-2 by CBP/p300 recruitment. Mol Cell Biol (2004) 1.89
DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC. Cell (2010) 1.89
The allantois and chorion, when isolated before circulation or chorio-allantoic fusion, have hematopoietic potential. Development (2006) 1.88
The GNUMAP algorithm: unbiased probabilistic mapping of oligonucleotides from next-generation sequencing. Bioinformatics (2009) 1.83
Erythroid/myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells. Cell Stem Cell (2011) 1.76
CBFbeta is critical for AML1-ETO and TEL-AML1 activity. Blood (2009) 1.74
An ERK2 docking site in the Pointed domain distinguishes a subset of ETS transcription factors. Genes Dev (2002) 1.73
Core binding factors are necessary for natural killer cell development and cooperate with Notch signaling during T-cell specification. Blood (2008) 1.67
Pathoscope: species identification and strain attribution with unassembled sequencing data. Genome Res (2013) 1.62
The structural and dynamic basis of Ets-1 DNA binding autoinhibition. J Biol Chem (2004) 1.62
Whole-mount three-dimensional imaging of internally localized immunostained cells within mouse embryos. Nat Protoc (2012) 1.58
Oncogenic ETS proteins mimic activated RAS/MAPK signaling in prostate cells. Genes Dev (2011) 1.56
A single-sample microarray normalization method to facilitate personalized-medicine workflows. Genomics (2012) 1.55
Trisomy 21-associated defects in human primitive hematopoiesis revealed through induced pluripotent stem cells. Proc Natl Acad Sci U S A (2012) 1.54
Nascent peptides that block protein synthesis in bacteria. Proc Natl Acad Sci U S A (2013) 1.52
Attenuation of AML1-ETO cellular dysregulation correlates with increased leukemogenic potential. Blood (2013) 1.46
Allosteric inhibition of the protein-protein interaction between the leukemia-associated proteins Runx1 and CBFbeta. Chem Biol (2007) 1.44
Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles. EMBO J (2007) 1.44
Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity. Cancer Cell (2007) 1.43
The core-binding factor beta subunit is required for bone formation and hematopoietic maturation. Nat Genet (2002) 1.36
Leukemia and hematopoietic stem cells: balancing proliferation and quiescence. Cell Cycle (2008) 1.28
The expression of Sox17 identifies and regulates haemogenic endothelium. Nat Cell Biol (2013) 1.28
Structural analysis of the autoinhibition of Ets-1 and its role in protein partnerships. J Biol Chem (2002) 1.25
Runx1 function in hematopoiesis is required in cells that express Tek. Blood (2005) 1.25
Runx1 deletion or dominant inhibition reduces Cebpa transcription via conserved promoter and distal enhancer sites to favor monopoiesis over granulopoiesis. Blood (2012) 1.22
Runx1 is expressed in adult mouse hematopoietic stem cells and differentiating myeloid and lymphoid cells, but not in maturing erythroid cells. Stem Cells (2004) 1.21
Gene deregulation and chronic activation in natural killer cells deficient in the transcription factor ETS1. Immunity (2012) 1.18
RUNX1 mutations in clonal myeloid disorders: from conventional cytogenetics to next generation sequencing, a story 40 years in the making. Crit Rev Oncog (2011) 1.15
A flexible and powerful bayesian hierarchical model for ChIP-Chip experiments. Biometrics (2007) 1.14
DNA binding by the ETS protein TEL (ETV6) is regulated by autoinhibition and self-association. J Biol Chem (2010) 1.13
Endothelio-mesenchymal interaction controls runx1 expression and modulates the notch pathway to initiate aortic hematopoiesis. Dev Cell (2013) 1.13
Energetic contribution of residues in the Runx1 Runt domain to DNA binding. J Biol Chem (2003) 1.12
T-lymphoid, megakaryocyte, and granulocyte development are sensitive to decreases in CBFbeta dosage. Blood (2006) 1.11
Hematopoietic stem cell emergence in the conceptus and the role of Runx1. Int J Dev Biol (2010) 1.11
The affinity of Ets-1 for DNA is modulated by phosphorylation through transient interactions of an unstructured region. J Mol Biol (2008) 1.10
CBFbeta allosterically regulates the Runx1 Runt domain via a dynamic conformational equilibrium. Nat Struct Mol Biol (2004) 1.08
Runx1 loss minimally impacts long-term hematopoietic stem cells. PLoS One (2011) 1.06
Improved annotation of C. elegans microRNAs by deep sequencing reveals structures associated with processing by Drosha and Dicer. RNA (2011) 1.05
Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells. Development (2013) 1.05
Runx1 deficiency predisposes mice to T-lymphoblastic lymphoma. Blood (2005) 1.04
Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila model. Blood (2010) 1.02
Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to coactivator CBP. Proc Natl Acad Sci U S A (2010) 1.01
Multiplatform single-sample estimates of transcriptional activation. Proc Natl Acad Sci U S A (2013) 1.00
Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity. Blood (2009) 0.98
Inhibitory module of Ets-1 allosterically regulates DNA binding through a dipole-facilitated phosphate contact. J Biol Chem (2001) 0.97
Effects of ADARs on small RNA processing pathways in C. elegans. Genome Res (2012) 0.97
The ETS gene ETV4 is required for anchorage-independent growth and a cell proliferation gene expression program in PC3 prostate cells. Genes Cancer (2011) 0.97
Possible roles of Runx1 and Sox9 in incipient intramembranous ossification. J Bone Miner Res (2004) 0.96
Autoinhibition of ETV6 (TEL) DNA binding: appended helices sterically block the ETS domain. J Mol Biol (2012) 0.93
Altered affinity of CBF beta-SMMHC for Runx1 explains its role in leukemogenesis. Nat Struct Biol (2002) 0.92
Runx1 dose-dependently regulates endochondral ossification during skeletal development and fracture healing. J Bone Miner Res (2012) 0.91
Mutagenesis of the Runt domain defines two energetic hot spots for heterodimerization with the core binding factor beta subunit. J Biol Chem (2003) 0.90
Beads-on-a-string, characterization of ETS-1 sumoylated within its flexible N-terminal sequence. J Biol Chem (2005) 0.89
Role of Ets-1 phosphorylation in the effector function of Th cells. Eur J Immunol (2008) 0.88
Ets-1 flips for new partner Pax-5. Structure (2002) 0.85
ETS-4 is a transcriptional regulator of life span in Caenorhabditis elegans. PLoS Genet (2010) 0.85
Structural and functional characterization of Runx1, CBF beta, and CBF beta-SMMHC. Blood Cells Mol Dis (2003) 0.85
Runx1 and Cbfβ regulate the development of Flt3+ dendritic cell progenitors and restrict myeloproliferative disorder. Blood (2014) 0.84
The role of CBFbeta in AML1-ETO's activity. Blood (2009) 0.84
Structure of the AML1-ETO NHR3-PKA(RIIα) complex and its contribution to AML1-ETO activity. J Mol Biol (2010) 0.83
Genomic pathway analysis reveals that EZH2 and HDAC4 represent mutually exclusive epigenetic pathways across human cancers. BMC Med Genomics (2013) 0.83
Identification and structural characterization of a CBP/p300-binding domain from the ETS family transcription factor GABP alpha. J Mol Biol (2008) 0.82
Visualizing blood cell emergence from aortic endothelium. Cell Stem Cell (2010) 0.82
A mutation in the S-switch region of the Runt domain alters the dynamics of an allosteric network responsible for CBFbeta regulation. J Mol Biol (2006) 0.81
A MENage à Trois in leukemia. Cancer Cell (2008) 0.81
Census-based rapid and accurate metagenome taxonomic profiling. BMC Genomics (2014) 0.81
Detection and assignment of phosphoserine and phosphothreonine residues by (13)C- (31)P spin-echo difference NMR spectroscopy. J Biomol NMR (2008) 0.79
Tyrosyl phosphorylation toggles a Runx1 switch. Genes Dev (2012) 0.78
Dual views of SRF: a genomic exposure. Genes Dev (2014) 0.76
Parallel Mapping Approaches for GNUMAP. IPDPS (2011) 0.75