PubRank

Rik Gijsbers

Author PubWeight™ 53.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Transportin-SR2 imports HIV into the nucleus. Curr Biol 2008 2.35
2 Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus. J Virol 2006 2.09
3 Long-term reversal of diabetes in non-obese diabetic mice by liver-directed gene therapy. J Gene Med 2013 2.02
4 Overexpression of the lens epithelium-derived growth factor/p75 integrase binding domain inhibits human immunodeficiency virus replication. J Virol 2006 1.82
5 Highly efficient multicistronic lentiviral vectors with peptide 2A sequences. Hum Gene Ther 2009 1.54
6 Comparison of lentiviral vector titration methods. BMC Biotechnol 2006 1.42
7 Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV. PLoS Pathog 2007 1.41
8 Upscaling of lentiviral vector production by tangential flow filtration. J Gene Med 2005 1.38
9 Lens epithelium-derived growth factor/p75 interacts with the transposase-derived DDE domain of PogZ. J Biol Chem 2009 1.30
10 The BET family of proteins targets moloney murine leukemia virus integration near transcription start sites. Cell Rep 2013 1.26
11 LEDGF/p75-independent HIV-1 replication demonstrates a role for HRP-2 and remains sensitive to inhibition by LEDGINs. PLoS Pathog 2012 1.25
12 LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions. Retrovirology 2013 1.17
13 Interplay between HIV entry and transportin-SR2 dependency. Retrovirology 2011 1.17
14 Differential interaction of HIV-1 integrase and JPO2 with the C terminus of LEDGF/p75. J Mol Biol 2007 1.14
15 Noninvasive monitoring of long-term lentiviral vector-mediated gene expression in rodent brain with bioluminescence imaging. Mol Ther 2006 1.11
16 The transcriptional co-activator LEDGF/p75 displays a dynamic scan-and-lock mechanism for chromatin tethering. Nucleic Acids Res 2010 1.08
17 High-resolution profiling of the LEDGF/p75 chromatin interaction in the ENCODE region. Nucleic Acids Res 2010 1.08
18 Substrate-specifying determinants of the nucleotide pyrophosphatases/phosphodiesterases NPP1 and NPP2. Biochem J 2004 1.08
19 Alternative splicing and caspase-mediated cleavage generate antagonistic variants of the stress oncoprotein LEDGF/p75. Mol Cancer Res 2008 1.04
20 State-of-the-art lentiviral vectors for research use: risk assessment and biosafety recommendations. Curr Gene Ther 2009 1.00
21 Noninvasive and quantitative monitoring of adult neuronal stem cell migration in mouse brain using bioluminescence imaging. Stem Cells 2008 0.99
22 Parkin protects against neurotoxicity in the 6-hydroxydopamine rat model for Parkinson's disease. Mol Ther 2006 0.99
23 miR669a and miR669q prevent skeletal muscle differentiation in postnatal cardiac progenitors. J Cell Biol 2011 0.99
24 Single-cell imaging of HIV-1 provirus (SCIP). Proc Natl Acad Sci U S A 2013 0.98
25 Association of polymorphisms in the LEDGF/p75 gene (PSIP1) with susceptibility to HIV-1 infection and disease progression. AIDS 2011 0.97
26 HRP-2 determines HIV-1 integration site selection in LEDGF/p75 depleted cells. Retrovirology 2012 0.94
27 Immunohistochemical detection of transgene expression in the brain using small epitope tags. BMC Biotechnol 2010 0.93
28 PEAR1 attenuates megakaryopoiesis via control of the PI3K/PTEN pathway. Blood 2013 0.90
29 Pathway specific gene expression profiling reveals oxidative stress genes potentially regulated by transcription co-activator LEDGF/p75 in prostate cancer cells. Prostate 2011 0.89
30 Phage display-directed discovery of LEDGF/p75 binding cyclic peptide inhibitors of HIV replication. Mol Ther 2012 0.89
31 Lens epithelium-derived growth factor/p75 qualifies as a target for HIV gene therapy in the NSG mouse model. Mol Ther 2012 0.88
32 Diffusion of myelin oligodendrocyte glycoprotein in living OLN-93 cells investigated by raster-scanning image correlation spectroscopy (RICS). J Fluoresc 2008 0.87
33 A PET brain reporter gene system based on type 2 cannabinoid receptors. J Nucl Med 2011 0.87
34 Long-term miR-669a therapy alleviates chronic dilated cardiomyopathy in dystrophic mice. J Am Heart Assoc 2013 0.87
35 Efficient gene transfer into the mouse lung by fetal intratracheal injection of rAAV2/6.2. Mol Ther 2010 0.86
36 Synthesis and evaluation of 18F- and 11C-labeled phenyl-galactopyranosides as potential probes for in vivo visualization of LacZ gene expression using positron emission tomography. Bioconjug Chem 2008 0.86
37 Fetal gene transfer with lentiviral vectors: long-term in vivo follow-up evaluation in a rat model. Am J Obstet Gynecol 2007 0.85
38 Regulator of G-protein signaling 18 controls megakaryopoiesis and the cilia-mediated vertebrate mechanosensory system. FASEB J 2012 0.84
39 Transient Expression of an LEDGF/p75 Chimera Retargets Lentivector Integration and Functionally Rescues in a Model for X-CGD. Mol Ther Nucleic Acids 2013 0.83
40 Quantitation of HIV DNA integration: effects of differential integration site distributions on Alu-PCR assays. J Virol Methods 2013 0.81
41 Immunological ignorance allows long-term gene expression after perinatal recombinant adeno-associated virus-mediated gene transfer to murine airways. Hum Gene Ther 2014 0.81
42 Synthesis and biological evaluation of (11)C-labeled beta-galactosyl triazoles as potential PET tracers for in vivo LacZ reporter gene imaging. Bioorg Med Chem 2009 0.80
43 The α crystallin domain of small heat shock protein b8 (Hspb8) acts as survival and differentiation factor in adult hippocampal neurogenesis. J Neurosci 2013 0.80
44 HIV-1 IN/Pol recruits LEDGF/p75 into viral particles. Retrovirology 2015 0.79
45 Controlling and monitoring stem cell safety in vivo in an experimental rodent model. Stem Cells 2014 0.79
46 Preliminary validation of varicella zoster virus thymidine kinase as a novel reporter gene for PET. Nucl Med Biol 2012 0.78
47 Synthesis and preliminary evaluation of 18F- or 11C-labeled bicyclic nucleoside analogues as potential probes for imaging varicella-zoster virus thymidine kinase gene expression using positron emission tomography. J Med Chem 2007 0.78
48 Recipient leukocyte infusion enhances the local and systemic graft-versus-neuroblastoma effect of allogeneic bone marrow transplantation in mice. Cancer Immunol Immunother 2013 0.78
49 1,25-Dihydroxyvitamin D3 and the aging-related forkhead box O and sestrin proteins in osteoblasts. J Steroid Biochem Mol Biol 2012 0.78
50 Characterization of rare lens epithelium-derived growth factor/p75 genetic variants identified in HIV-1 long-term nonprogressors. AIDS 2013 0.77
51 Synthesis and biological evaluation of an 123I-labeled bicyclic nucleoside analogue (BCNA) as potential SPECT tracer for VZV-tk reporter gene imaging. Bioorg Med Chem Lett 2007 0.75
52 A p-[18F]fluoroethoxyphenyl bicyclic nucleoside analogue as a potential positron emission tomography imaging agent for varicella-zoster virus thymidine kinase gene expression. J Med Chem 2007 0.75