Published in Development on January 01, 2010
Steroid hormone inactivation is required during the juvenile-adult transition in Drosophila. Dev Cell (2010) 1.07
SAYP and Brahma are important for 'repressive' and 'transient' Pol II pausing. Nucleic Acids Res (2012) 1.03
MLT-10 defines a family of DUF644 and proline-rich repeat proteins involved in the molting cycle of Caenorhabditis elegans. Mol Biol Cell (2010) 0.95
Distinct roles of isoforms of the heme-liganded nuclear receptor E75, an insect ortholog of the vertebrate Rev-erb, in mosquito reproduction. Mol Cell Endocrinol (2011) 0.92
Scavenger receptors mediate the role of SUMO and Ftz-f1 in Drosophila steroidogenesis. PLoS Genet (2013) 0.92
A critical role of the nuclear receptor HR3 in regulation of gonadotrophic cycles of the mosquito Aedes aegypti. PLoS One (2012) 0.87
Temporally tuned neuronal differentiation supports the functional remodeling of a neuronal network in Drosophila. Proc Natl Acad Sci U S A (2012) 0.84
Identification of genes required for neural-specific glycosylation using functional genomics. PLoS Genet (2010) 0.80
The nuclear receptor genes HR3 and E75 are required for the circadian rhythm in a primitive insect. PLoS One (2014) 0.79
Functional conservation of Drosophila FTZ-F1 and its mammalian homologs suggests ligand-independent regulation of NR5A family transcriptional activity. Dev Genes Evol (2013) 0.76
Knockdown of a nutrient amino acid transporter gene LdNAT1 reduces free neutral amino acid contents and impairs Leptinotarsa decemlineata pupation. Sci Rep (2015) 0.76
The study of the Bithorax-complex genes in patterning CCAP neurons reveals a temporal control of neuronal differentiation by Abd-B. Biol Open (2015) 0.75
Steroid Hormones and the Physiological Regulation of Tissue-Resident Stem Cells: Lessons from the Drosophila Ovary. Curr Stem Cell Rep (2017) 0.75
Larval diapause termination in the bamboo borer, Omphisa fuscidentalis. PLoS One (2017) 0.75
Differentiated muscles are mandatory for gas-filling of the Drosophila airway system. Biol Open (2015) 0.75
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc (2009) 137.99
DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol (2003) 84.79
The hardwiring of development: organization and function of genomic regulatory systems. Development (1997) 5.55
Ordering genes in a flagella pathway by analysis of expression kinetics from living bacteria. Science (2001) 3.69
The Drosophila EcR gene encodes an ecdysone receptor, a new member of the steroid receptor superfamily. Cell (1991) 3.57
The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules. Cell (1993) 3.48
The Drosophila nuclear receptor e75 contains heme and is gas responsive. Cell (2005) 2.73
Disruption of the nuclear hormone receptor RORalpha in staggerer mice. Nature (1996) 2.58
Molecular mechanisms of developmental timing in C. elegans and Drosophila. Dev Cell (2001) 2.45
Ecdysone receptors and their biological actions. Vitam Horm (2000) 2.18
FTZ-F1, a steroid hormone receptor-like protein implicated in the activation of fushi tarazu. Science (1991) 2.05
The Drosophila beta FTZ-F1 orphan nuclear receptor provides competence for stage-specific responses to the steroid hormone ecdysone. Mol Cell (1999) 1.87
The Drosophila disembodied gene controls late embryonic morphogenesis and codes for a cytochrome P450 enzyme that regulates embryonic ecdysone levels. Development (2000) 1.84
The nuclear hormone receptor Ftz-F1 is a cofactor for the Drosophila homeodomain protein Ftz. Nature (1997) 1.82
New fluorescent protein reporters for use with the Drosophila Gal4 expression system and for vital detection of balancer chromosomes. Genesis (2002) 1.80
Sequential pulses of apical epithelial secretion and endocytosis drive airway maturation in Drosophila. Dev Cell (2007) 1.79
Drosophila ecdysone receptor mutations reveal functional differences among receptor isoforms. Cell (1997) 1.75
Coordination of Drosophila metamorphosis by two ecdysone-induced nuclear receptors. Science (1997) 1.72
Genetic analysis of the mechanisms controlling target selection: complementary and combinatorial functions of netrins, semaphorins, and IgCAMs. Cell (1998) 1.71
The nuclear receptor homologue Ftz-F1 and the homeodomain protein Ftz are mutually dependent cofactors. Nature (1997) 1.65
Ecdysteroid regulation and DNA binding properties of Drosophila nuclear hormone receptor superfamily members. Dev Biol (1995) 1.60
Spook and Spookier code for stage-specific components of the ecdysone biosynthetic pathway in Diptera. Dev Biol (2006) 1.57
Requirement for chitin biosynthesis in epithelial tube morphogenesis. Proc Natl Acad Sci U S A (2005) 1.56
A new family of Drosophila balancer chromosomes with a w- dfd-GMR yellow fluorescent protein marker. Genetics (2006) 1.55
RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways. Neuron (2003) 1.53
A molecular mechanism for the stage specificity of the Drosophila prepupal genetic response to ecdysone. Cell (1994) 1.45
Loss of the ecdysteroid-inducible E75A orphan nuclear receptor uncouples molting from metamorphosis in Drosophila. Dev Cell (2002) 1.41
Condensation of the central nervous system in embryonic Drosophila is inhibited by blocking hemocyte migration or neural activity. Dev Biol (2005) 1.39
Temporal profiles of nuclear receptor gene expression reveal coordinate transcriptional responses during Drosophila development. Mol Endocrinol (2003) 1.35
Staggerer, a new mutation in the mouse affecting the cerebellum. Science (1962) 1.33
Coordination of larval and prepupal gene expression by the DHR3 orphan receptor during Drosophila metamorphosis. Development (1997) 1.29
Ecdysone coordinates the timing and amounts of E74A and E74B transcription in Drosophila. Genes Dev (1991) 1.29
DHR3 is required for the prepupal-pupal transition and differentiation of adult structures during Drosophila metamorphosis. Dev Biol (1999) 1.27
Essential roles for ecdysone signaling during Drosophila mid-embryonic development. Science (2003) 1.26
Recent advances in the mechanisms of action and physiological functions of the retinoid-related orphan receptors (RORs). Curr Drug Targets Inflamm Allergy (2004) 1.22
Temporally restricted expression of transcription factor betaFTZ-F1: significance for embryogenesis, molting and metamorphosis in Drosophila melanogaster. Development (2000) 1.22
The ecdysone-induced DHR4 orphan nuclear receptor coordinates growth and maturation in Drosophila. Cell (2005) 1.19
Expression and function of the homoeotic genes Antennapedia and Sex combs reduced in the embryonic midgut of Drosophila. Development (1990) 1.19
Peptide hormones, steroid hormones, and puffs: mechanisms and models in insect development. Vitam Horm (1999) 1.17
ROR alpha in genetic control of cerebellum development: 50 staggering years. Brain Res (2006) 1.16
A conditional rescue system reveals essential functions for the ecdysone receptor (EcR) gene during molting and metamorphosis in Drosophila. Development (2000) 1.13
Tubulogenesis: an inside job. Curr Biol (2006) 1.12
The Drosophila E93 gene from the 93F early puff displays stage- and tissue-specific regulation by 20-hydroxyecdysone. Dev Biol (1995) 1.11
pipsqueak encodes a novel nuclear protein required downstream of seven-up for the development of photoreceptors R3 and R4. EMBO J (1995) 1.05
Drosophila signal peptide peptidase is an essential protease for larval development. Genetics (2005) 1.01
Temporal regulation of the mid-prepupal gene FTZ-F1: DHR3 early late gene product is one of the plural positive regulators. Genes Cells (1997) 0.97
DHR3, an ecdysone-inducible early-late gene encoding a Drosophila nuclear receptor, is required for embryogenesis. Proc Natl Acad Sci U S A (1997) 0.96
Multiple roles for apoptosis facilitating condensation of the Drosophila ventral nerve cord. Genesis (2008) 0.83
A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans. Science (2012) 3.39
Diabetic larvae and obese flies-emerging studies of metabolism in Drosophila. Cell Metab (2007) 2.99
Nuclear receptors--a perspective from Drosophila. Nat Rev Genet (2005) 2.65
Prothoracicotropic hormone regulates developmental timing and body size in Drosophila. Dev Cell (2007) 2.33
The DHR96 nuclear receptor controls triacylglycerol homeostasis in Drosophila. Cell Metab (2009) 2.23
Drosophila HNF4 regulates lipid mobilization and beta-oxidation. Cell Metab (2009) 2.00
The genomic response to 20-hydroxyecdysone at the onset of Drosophila metamorphosis. Genome Biol (2005) 1.93
Coordinate regulation of small temporal RNAs at the onset of Drosophila metamorphosis. Dev Biol (2003) 1.79
Mechanisms of steroid-triggered programmed cell death in Drosophila. Semin Cell Dev Biol (2005) 1.69
The DHR96 nuclear receptor regulates xenobiotic responses in Drosophila. Cell Metab (2006) 1.66
The Drosophila estrogen-related receptor directs a metabolic switch that supports developmental growth. Cell Metab (2011) 1.48
The Drosophila orphan nuclear receptor DHR38 mediates an atypical ecdysteroid signaling pathway. Cell (2003) 1.44
Loss of the ecdysteroid-inducible E75A orphan nuclear receptor uncouples molting from metamorphosis in Drosophila. Dev Cell (2002) 1.41
Coordinating growth and maturation - insights from Drosophila. Curr Biol (2011) 1.38
Temporal profiles of nuclear receptor gene expression reveal coordinate transcriptional responses during Drosophila development. Mol Endocrinol (2003) 1.35
Essential roles for ecdysone signaling during Drosophila mid-embryonic development. Science (2003) 1.26
Transcriptional regulation of xenobiotic detoxification in Drosophila. Genes Dev (2011) 1.25
A balance between the diap1 death inhibitor and reaper and hid death inducers controls steroid-triggered cell death in Drosophila. Proc Natl Acad Sci U S A (2004) 1.22
Dynamic regulation of Drosophila nuclear receptor activity in vivo. Development (2006) 1.21
The ecdysone-induced DHR4 orphan nuclear receptor coordinates growth and maturation in Drosophila. Cell (2005) 1.19
The Drosophila DHR96 nuclear receptor binds cholesterol and regulates cholesterol homeostasis. Genes Dev (2009) 1.19
Down-regulation of inhibitor of apoptosis levels provides competence for steroid-triggered cell death. J Cell Biol (2007) 1.12
Coordination of triacylglycerol and cholesterol homeostasis by DHR96 and the Drosophila LipA homolog magro. Cell Metab (2011) 1.10
GFP in living animals reveals dynamic developmental responses to ecdysone during Drosophila metamorphosis. Dev Biol (2003) 1.04
The circadian clock, light, and cryptochrome regulate feeding and metabolism in Drosophila. J Biol Rhythms (2011) 1.03
rigor mortis encodes a novel nuclear receptor interacting protein required for ecdysone signaling during Drosophila larval development. Development (2003) 1.01
The Drosophila NR4A nuclear receptor DHR38 regulates carbohydrate metabolism and glycogen storage. Mol Endocrinol (2010) 0.98
A genetic screen identifies new regulators of steroid-triggered programmed cell death in Drosophila. Genetics (2008) 0.98
Genetic modifier screens in Drosophila demonstrate a role for Rho1 signaling in ecdysone-triggered imaginal disc morphogenesis. Genetics (2003) 0.97
Developmental timing: let-7 function conserved through evolution. Curr Biol (2008) 0.97
Indicted: worms caught using steroids. Cell (2006) 0.97
Spatial patterns of ecdysteroid receptor activation during the onset of Drosophila metamorphosis. Development (2002) 0.96
Med24 and Mdh2 are required for Drosophila larval salivary gland cell death. Dev Dyn (2010) 0.92
Specific transcriptional responses to juvenile hormone and ecdysone in Drosophila. Insect Biochem Mol Biol (2007) 0.91
dTrf2 is required for transcriptional and developmental responses to ecdysone during Drosophila metamorphosis. Dev Dyn (2007) 0.87
Serotonin and insulin signaling team up to control growth in Drosophila. Genes Dev (2008) 0.82
Developmental biology. Less steroids make bigger flies. Science (2005) 0.81
Constitutive activation of the Nrf2/Keap1 pathway in insecticide-resistant strains of Drosophila. Insect Biochem Mol Biol (2013) 0.81
Methods to characterize Drosophila nuclear receptor activation and function in vivo. Methods Enzymol (2003) 0.81
Drosophila DHR38 nuclear receptor is required for adult cuticle integrity at eclosion. Dev Dyn (2009) 0.81
Functional interactions between the Moses corepressor and DHR78 nuclear receptor regulate growth in Drosophila. Genes Dev (2007) 0.79
Essential roles for the Dhr78 orphan nuclear receptor during molting of the Drosophila tracheal system. Insect Biochem Mol Biol (2003) 0.76
Will branch for food-nutrient-dependent tracheal remodeling in Drosophila. EMBO J (2014) 0.75