Published in Cell Metab on March 01, 2009
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High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila. Cell Metab (2010) 2.50
A hormone-dependent module regulating energy balance. Cell (2011) 2.30
The DHR96 nuclear receptor controls triacylglycerol homeostasis in Drosophila. Cell Metab (2009) 2.23
An obligatory role for neurotensin in high-fat-diet-induced obesity. Nature (2016) 2.18
Drosophila cytokine unpaired 2 regulates physiological homeostasis by remotely controlling insulin secretion. Cell (2012) 2.06
Comparative metabolomics reveals endogenous ligands of DAF-12, a nuclear hormone receptor, regulating C. elegans development and lifespan. Cell Metab (2014) 1.60
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The Drosophila estrogen-related receptor directs a metabolic switch that supports developmental growth. Cell Metab (2011) 1.48
Functional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network. Mol Syst Biol (2010) 1.40
Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation. PLoS Genet (2011) 1.30
The skinny on fat: lipolysis and fatty acid utilization in adipocytes. Trends Endocrinol Metab (2009) 1.22
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Hepatocyte nuclear factor 4alpha coordinates a transcription factor network regulating hepatic fatty acid metabolism. Mol Cell Biol (2009) 1.18
Rab32 is important for autophagy and lipid storage in Drosophila. PLoS One (2012) 1.16
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Identification of genes with a correlation between copy number and expression in gastric cancer. BMC Med Genomics (2012) 1.11
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A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses. Nat Struct Mol Biol (2010) 1.06
A buoyancy-based screen of Drosophila larvae for fat-storage mutants reveals a role for Sir2 in coupling fat storage to nutrient availability. PLoS Genet (2010) 1.06
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The function of nuclear receptors in regulation of female reproduction and embryogenesis in the red flour beetle, Tribolium castaneum. J Insect Physiol (2010) 0.95
Regulation of energy stores and feeding by neuronal and peripheral CREB activity in Drosophila. PLoS One (2009) 0.93
Scavenger receptors mediate the role of SUMO and Ftz-f1 in Drosophila steroidogenesis. PLoS Genet (2013) 0.92
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The role of nuclear receptor NHR-64 in fat storage regulation in Caenorhabditis elegans. PLoS One (2010) 0.90
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Suppression of insulin production and secretion by a decretin hormone. Cell Metab (2015) 0.88
HNF4α antagonists discovered by a high-throughput screen for modulators of the human insulin promoter. Chem Biol (2012) 0.88
Network-based analysis of genome wide association data provides novel candidate genes for lipid and lipoprotein traits. Mol Cell Proteomics (2013) 0.87
Proneural and abdominal Hox inputs synergize to promote sensory organ formation in the Drosophila abdomen. Dev Biol (2010) 0.84
Hepatocyte nuclear factor 4α and downstream secreted phospholipase A2 GXIIB regulate production of infectious hepatitis C virus. J Virol (2013) 0.84
Adipocyte amino acid sensing controls adult germline stem cell number via the amino acid response pathway and independently of Target of Rapamycin signaling in Drosophila. Development (2014) 0.83
Whole transcriptome analysis of a reversible neurodegenerative process in Drosophila reveals potential neuroprotective genes. BMC Genomics (2012) 0.83
High-resolution protein interaction map of the Drosophila melanogaster p38 mitogen-activated protein kinases reveals limited functional redundancy. Mol Cell Biol (2012) 0.83
Systemic Activin signaling independently regulates sugar homeostasis, cellular metabolism, and pH balance in Drosophila melanogaster. Proc Natl Acad Sci U S A (2014) 0.82
Feeding and Fasting Signals Converge on the LKB1-SIK3 Pathway to Regulate Lipid Metabolism in Drosophila. PLoS Genet (2015) 0.82
From SNP co-association to RNA co-expression: novel insights into gene networks for intramuscular fatty acid composition in porcine. BMC Genomics (2014) 0.81
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Temporal Coordination of Carbohydrate Metabolism during Mosquito Reproduction. PLoS Genet (2015) 0.79
Oenocyte development in the red flour beetle Tribolium castaneum. Dev Genes Evol (2012) 0.78
Systemic corazonin signalling modulates stress responses and metabolism in Drosophila. Open Biol (2016) 0.78
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The metabolic control of schistosome egg production. Cell Microbiol (2015) 0.77
dMyc expression in the fat body affects DILP2 release and increases the expression of the fat desaturase Desat1 resulting in organismal growth. Dev Biol (2013) 0.77
Glial β-oxidation regulates Drosophila energy metabolism. Sci Rep (2015) 0.77
The composition and organization of Drosophila heterochromatin are heterogeneous and dynamic. Elife (2016) 0.77
The lipolysis pathway sustains normal and transformed stem cells in adult Drosophila. Nature (2016) 0.77
Curcumin enhances parental reproductive lifespan and progeny viability in Drosophila melanogaster. Age (Dordr) (2014) 0.76
Spastin binds to lipid droplets and affects lipid metabolism. PLoS Genet (2015) 0.76
Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha. Genome Res (2017) 0.76
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Gain-of-Function Alleles in Caenorhabditis elegans Nuclear Hormone Receptor nhr-49 Are Functionally Distinct. PLoS One (2016) 0.75
The corticotropin-releasing factor-like diuretic hormone 44 (DH44) and kinin neuropeptides modulate desiccation and starvation tolerance in Drosophila melanogaster. Peptides (2016) 0.75
A fat-derived metabolite regulates a peptidergic feeding circuit in Drosophila. PLoS Biol (2017) 0.75
Roles of Vitamin A Metabolism in the Development of Hepatic Insulin Resistance. ISRN Hepatol (2013) 0.75
Genes Related to Fatty Acid β-Oxidation Play a Role in the Functional Decline of the Drosophila Brain with Age. PLoS One (2016) 0.75
Sir2 Acts through Hepatocyte Nuclear Factor 4 to maintain insulin Signaling and Metabolic Homeostasis in Drosophila. PLoS Genet (2016) 0.75
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The Drosophila HNF4 nuclear receptor promotes glucose-stimulated insulin secretion and mitochondrial function in adults. Elife (2016) 0.75
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Hormone and receptor interplay in the regulation of mosquito lipid metabolism. Proc Natl Acad Sci U S A (2017) 0.75
Drosophila TRF2 and TAF9 regulate lipid droplet size and phospholipid fatty acid composition. PLoS Genet (2017) 0.75
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Control of pancreas and liver gene expression by HNF transcription factors. Science (2004) 12.05
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature (2001) 11.72
Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis. Mol Cell Biol (2001) 8.95
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Role and regulation of starvation-induced autophagy in the Drosophila fat body. Dev Cell (2004) 8.53
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Drosophila's insulin/PI3-kinase pathway coordinates cellular metabolism with nutritional conditions. Dev Cell (2002) 4.85
Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway. Dev Cell (2004) 4.53
Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis. Proc Natl Acad Sci U S A (2003) 4.34
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A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49. Proc Natl Acad Sci U S A (2005) 2.69
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Fatty acids and hypolipidemic drugs regulate peroxisome proliferator-activated receptors alpha - and gamma-mediated gene expression via liver fatty acid binding protein: a signaling path to the nucleus. Proc Natl Acad Sci U S A (2001) 2.37
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A modified tandem affinity purification strategy identifies cofactors of the Drosophila nuclear receptor dHNF4. Proteomics (2006) 0.97
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The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs. Dev Cell (2003) 6.86
A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans. Science (2012) 3.39
Diabetic larvae and obese flies-emerging studies of metabolism in Drosophila. Cell Metab (2007) 2.99
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The DHR96 nuclear receptor controls triacylglycerol homeostasis in Drosophila. Cell Metab (2009) 2.23
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The DHR96 nuclear receptor regulates xenobiotic responses in Drosophila. Cell Metab (2006) 1.66
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The Drosophila orphan nuclear receptor DHR38 mediates an atypical ecdysteroid signaling pathway. Cell (2003) 1.44
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Transcriptional regulation of xenobiotic detoxification in Drosophila. Genes Dev (2011) 1.25
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The Drosophila NR4A nuclear receptor DHR38 regulates carbohydrate metabolism and glycogen storage. Mol Endocrinol (2010) 0.98
A genetic screen identifies new regulators of steroid-triggered programmed cell death in Drosophila. Genetics (2008) 0.98
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Genetic modifier screens in Drosophila demonstrate a role for Rho1 signaling in ecdysone-triggered imaginal disc morphogenesis. Genetics (2003) 0.97
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The Drosophila nuclear receptors DHR3 and betaFTZ-F1 control overlapping developmental responses in late embryos. Development (2010) 0.96
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Serotonin and insulin signaling team up to control growth in Drosophila. Genes Dev (2008) 0.82
Developmental biology. Less steroids make bigger flies. Science (2005) 0.81
SVD identifies transcript length distribution functions from DNA microarray data and reveals evolutionary forces globally affecting GBM metabolism. PLoS One (2013) 0.81
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Drosophila DHR38 nuclear receptor is required for adult cuticle integrity at eclosion. Dev Dyn (2009) 0.81
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Essential roles for the Dhr78 orphan nuclear receptor during molting of the Drosophila tracheal system. Insect Biochem Mol Biol (2003) 0.76
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