Jacques Turgeon

Author PubWeight™ 36.67‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A comparison of six major platelet function tests to determine the prevalence of aspirin resistance in patients with stable coronary artery disease. Eur Heart J 2007 3.32
2 Factors predisposing to coma and delirium: fentanyl and midazolam exposure; CYP3A5, ABCB1, and ABCG2 genetic polymorphisms; and inflammatory factors. Crit Care Med 2013 2.31
3 The pharmacokinetics of ezetimibe. Can J Clin Pharmacol 2003 1.51
4 The ATP-binding cassette transporters and their implication in drug disposition: a special look at the heart. Pharmacol Rev 2006 1.16
5 How critical is the duration of the sampling scheme for the determination of half-life, characterization of exposure and assessment of bioequivalence? J Pharm Pharm Sci 2011 1.14
6 The dual role of pharmacogenetics in HIV treatment: mutations and polymorphisms regulating antiretroviral drug resistance and disposition. Pharmacol Rev 2012 1.10
7 The impact of a multidisciplinary information technology-supported program on blood pressure control in primary care. Circ Cardiovasc Qual Outcomes 2009 0.99
8 Prevalence and risk of potential cytochrome P450-mediated drug-drug interactions in older hospitalized patients with polypharmacy. Ann Pharmacother 2013 0.93
9 An evaluation of pharmacists' expectations towards pharmacogenomics. Pharmacogenomics 2013 0.90
10 Risperidone prolongs cardiac repolarization by blocking the rapid component of the delayed rectifier potassium current. J Cardiovasc Pharmacol 2003 0.90
11 Ten renin-angiotensin system-related gene polymorphisms in maximally treated Canadian Caucasian patients with heart failure. Br J Clin Pharmacol 2008 0.89
12 Validation of warfarin pharmacogenetic algorithms in clinical practice. Pharmacogenomics 2012 0.88
13 Drug-induced long QT syndrome in women: review of current evidence and remaining gaps. Gend Med 2008 0.86
14 The influence of CYP2D6 phenotype on the clinical response of nebivolol in patients with essential hypertension. Br J Clin Pharmacol 2006 0.84
15 Genetic determinants of response to aspirin: appraisal of 4 candidate genes. Thromb Res 2011 0.84
16 Lengthening of cardiac repolarization in isolated guinea pigs hearts by sequential or concomitant administration of two IKr blockers. J Pharm Sci 2010 0.84
17 Association between renal function and CYP3A5 genotype in heart transplant recipients treated with calcineurin inhibitors. J Heart Lung Transplant 2010 0.83
18 Clinical practice guideline: CYP2D6 genotyping for safe and efficacious codeine therapy. J Popul Ther Clin Pharmacol 2013 0.82
19 Assessing drug distribution in tissues expressing P-glycoprotein through physiologically based pharmacokinetic modeling: model structure and parameters determination. Theor Biol Med Model 2009 0.81
20 QRS widening and QT prolongation under bupropion: a unique cardiac electrophysiological profile. Fundam Clin Pharmacol 2011 0.81
21 Multiple-dose pharmacokinetic behavior of elvucitabine, a nucleoside reverse transcriptase inhibitor, administered over 21 days with lopinavir-ritonavir in human immunodeficiency virus type 1-infected subjects. Antimicrob Agents Chemother 2008 0.81
22 Detection and prevention of drug-drug interactions in the hospitalized elderly: utility of new cytochrome p450-based software. Am J Geriatr Pharmacother 2011 0.81
23 Drug-induced long QT syndrome and torsade de pointes. Can J Cardiol 2005 0.81
24 Gender-related differences in drug-induced prolongation of cardiac repolarization in prepubertal guinea pigs. J Cardiovasc Pharmacol Ther 2009 0.80
25 Metabolic activity and mRNA levels of human cardiac CYP450s involved in drug metabolism. PLoS One 2010 0.80
26 Domperidone and sudden cardiac death: How much longer should we wait? J Cardiovasc Pharmacol 2013 0.80
27 Olanzapine prolongs cardiac repolarization by blocking the rapid component of the delayed rectifier potassium current. J Psychopharmacol 2006 0.80
28 Effect of a single dose of ritonavir on the pharmacokinetic behavior of elvucitabine, a nucleoside reverse transcriptase inhibitor, administered in healthy volunteers. Antimicrob Agents Chemother 2008 0.80
29 Week-long high-maintenance dose clopidogrel regimen achieves better platelet aggregation inhibition than a standard loading dose before percutaneous coronary intervention: results of a double-blind, randomized clinical trial. J Interv Cardiol 2009 0.79
30 Platelet count, not oxidative stress, may contribute to inadequate platelet inhibition by aspirin. Int J Cardiol 2009 0.79
31 Effects of AGTR1 A1166C gene polymorphism in patients with heart failure treated with candesartan. Ann Pharmacother 2008 0.79
32 Impact of glucose concentration on cardiac ventricular repolarization under I Kr/I Ks blocking agents. J Mol Cell Cardiol 2009 0.79
33 Increased risk of myocardial infarction associated with angiotensin-converting enzyme gene polymorphism is age dependent. J Clin Pharmacol 2010 0.78
34 Role of CYP2D6 in the stereoselective disposition of venlafaxine in humans. Pharmacogenetics 2003 0.78
35 Characterization of CYP3A isozymes involved in the metabolism of domperidone: role of cytochrome b5 and inhibition by ketoconazole. Drug Metab Lett 2010 0.78
36 Clinical Practice Recommendations on Genetic Testing of CYP2C9 and VKORC1 Variants in Warfarin Therapy. Ther Drug Monit 2015 0.77
37 Rosuvastatin blocks hERG current and prolongs cardiac repolarization. J Pharm Sci 2011 0.77
38 PRKCB is associated with calcineurin inhibitor-induced renal dysfunction in heart transplant recipients. Pharmacogenet Genomics 2012 0.75
39 An improved HPLC assay with fluorescence detection for the determination of domperidone and three major metabolites for application to in vitro drug metabolism studies. J Chromatogr B Analyt Technol Biomed Life Sci 2007 0.75
40 Enantioselective quantification of carvedilol in human plasma by HPLC in heavily medicated heart failure patients. J Pharm Biomed Anal 2010 0.75
41 Modulatory role of verapamil treatment on the cardiac electrophysiological effects of cisapride. Can J Physiol Pharmacol 2006 0.75
42 Effects of ciprofloxacin on the stereoselective disposition of mexiletine in man. Ther Drug Monit 2004 0.75
43 Evaluation of Limited Sampling Methods for Oral Busulfan Pharmacokinetic Monitoring in Adult Patients Undergoing Hematopoietic Stem Cell Transplantation. Ther Drug Monit 2016 0.75
44 Inhibitory effects of propafenone on the pharmacokinetics of caffeine in humans. Ther Drug Monit 2006 0.75
45 Performance of different population pharmacokinetic algorithms. Ther Drug Monit 2011 0.75
46 Combined administration of quinidine and propafenone for atrial fibrillation: the CAQ-PAF study. J Clin Pharmacol 2012 0.75
47 Assessment of competitive and mechanism-based inhibition by clarithromycin: use of domperidone as a CYP3A probe-drug substrate and various enzymatic sources including a new cell-based assay with freshly isolated human hepatocytes. Drug Metab Lett 2010 0.75
48 High-dose venlafaxine treatment in a depressed patient with a genetic CYP2D6 deficiency. Int J Psychiatry Clin Pract 2004 0.75