PubRank

Mary-Ellen Harper

Author PubWeight™ 67.46‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 SirT1 regulates energy metabolism and response to caloric restriction in mice. PLoS One 2008 3.66
2 Rb and p107 regulate preadipocyte differentiation into white versus brown fat through repression of PGC-1alpha. Cell Metab 2005 2.76
3 Paradoxical resistance to diet-induced obesity in UCP1-deficient mice. J Clin Invest 2003 1.97
4 Uncoupling proteins and the control of mitochondrial reactive oxygen species production. Free Radic Biol Med 2011 1.91
5 MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16. Cell Metab 2013 1.87
6 Long-term caloric restriction increases UCP3 content but decreases proton leak and reactive oxygen species production in rat skeletal muscle mitochondria. Am J Physiol Endocrinol Metab 2005 1.77
7 Glutathionylation acts as a control switch for uncoupling proteins UCP2 and UCP3. J Biol Chem 2011 1.53
8 Electron transport chain-dependent and -independent mechanisms of mitochondrial H2O2 emission during long-chain fatty acid oxidation. J Biol Chem 2009 1.52
9 Uncoupling protein-3: clues in an ongoing mitochondrial mystery. FASEB J 2007 1.38
10 Uncoupling proteins and thermoregulation. J Appl Physiol (1985) 2002 1.34
11 Long-term calorie restriction reduces proton leak and hydrogen peroxide production in liver mitochondria. Am J Physiol Endocrinol Metab 2004 1.32
12 Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells. Diabetes 2005 1.31
13 Effects of short- and medium-term calorie restriction on muscle mitochondrial proton leak and reactive oxygen species production. Am J Physiol Endocrinol Metab 2004 1.30
14 Percent relative cumulative frequency analysis in indirect calorimetry: application to studies of transgenic mice. Can J Physiol Pharmacol 2004 1.24
15 Galactose enhances oxidative metabolism and reveals mitochondrial dysfunction in human primary muscle cells. PLoS One 2011 1.19
16 Essential role for uncoupling protein-3 in mitochondrial adaptation to fasting but not in fatty acid oxidation or fatty acid anion export. J Biol Chem 2008 1.19
17 Mitochondrial proticity and ROS signaling: lessons from the uncoupling proteins. Trends Endocrinol Metab 2012 1.15
18 Genipin-induced inhibition of uncoupling protein-2 sensitizes drug-resistant cancer cells to cytotoxic agents. PLoS One 2010 1.09
19 Gene expression profiling in whole blood identifies distinct biological pathways associated with obesity. BMC Med Genomics 2010 1.05
20 Unearthing the secrets of mitochondrial ROS and glutathione in bioenergetics. Trends Biochem Sci 2013 1.04
21 Long-term high-fat feeding induces greater fat storage in mice lacking UCP3. Am J Physiol Endocrinol Metab 2008 1.04
22 Glucose regulates enzymatic sources of mitochondrial NADPH in skeletal muscle cells; a novel role for glucose-6-phosphate dehydrogenase. FASEB J 2010 1.03
23 Gain-of-function R225W mutation in human AMPKgamma(3) causing increased glycogen and decreased triglyceride in skeletal muscle. PLoS One 2007 1.03
24 Distinct skeletal muscle fiber characteristics and gene expression in diet-sensitive versus diet-resistant obesity. J Lipid Res 2010 1.01
25 Crucial yet divergent roles of mitochondrial redox state in skeletal muscle vs. brown adipose tissue energetics. FASEB J 2011 1.00
26 Proton leak and hydrogen peroxide production in liver mitochondria from energy-restricted rats. Am J Physiol Endocrinol Metab 2004 0.99
27 Impaired adaptability of in vivo mitochondrial energetics to acute oxidative insult in aged skeletal muscle. Mech Ageing Dev 2012 0.99
28 The adipocyte-expressed forkhead transcription factor Foxc2 regulates metabolism through altered mitochondrial function. Diabetes 2011 0.98
29 FAT/CD36-null mice reveal that mitochondrial FAT/CD36 is required to upregulate mitochondrial fatty acid oxidation in contracting muscle. Am J Physiol Regul Integr Comp Physiol 2009 0.97
30 Rescue of neurons from ischemic injury by peroxisome proliferator-activated receptor-gamma requires a novel essential cofactor LMO4. J Neurosci 2008 0.95
31 Uncoupling proteins: role in insulin resistance and insulin insufficiency. Curr Diabetes Rev 2006 0.93
32 Peroxisome proliferator-activated receptor gamma 2 and acyl-CoA synthetase 5 polymorphisms influence diet response. Obesity (Silver Spring) 2007 0.93
33 Mitochondrial uncoupling as a target in the treatment of obesity. Curr Opin Clin Nutr Metab Care 2007 0.93
34 Effects of the presence, absence, and overexpression of uncoupling protein-3 on adiposity and fuel metabolism in congenic mice. Am J Physiol Endocrinol Metab 2006 0.93
35 SirT1 catalytic activity is required for male fertility and metabolic homeostasis in mice. FASEB J 2011 0.93
36 Hexokinase II acts through UCP3 to suppress mitochondrial reactive oxygen species production and maintain aerobic respiration. Biochem J 2011 0.93
37 Glutaredoxin-2 is required to control proton leak through uncoupling protein-3. J Biol Chem 2013 0.92
38 Intrinsic aerobic capacity correlates with greater inherent mitochondrial oxidative and H2O2 emission capacities without major shifts in myosin heavy chain isoform. J Appl Physiol (1985) 2012 0.91
39 Glutathionylation state of uncoupling protein-2 and the control of glucose-stimulated insulin secretion. J Biol Chem 2012 0.89
40 The SIRT1 deacetylase protects mice against the symptoms of metabolic syndrome. FASEB J 2013 0.88
41 Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria. PLoS One 2010 0.87
42 Muscle uncoupling protein 3 overexpression mimics endurance training and reduces circulating biomarkers of incomplete β-oxidation. FASEB J 2013 0.87
43 Glutathionylation of UCP2 sensitizes drug resistant leukemia cells to chemotherapeutics. Biochim Biophys Acta 2012 0.87
44 The energetic implications of uncoupling protein-3 in skeletal muscle. Appl Physiol Nutr Metab 2007 0.86
45 Sympathetic nervous dysregulation in the absence of systolic left ventricular dysfunction in a rat model of insulin resistance with hyperglycemia. Cardiovasc Diabetol 2011 0.86
46 Mitochondrial uncoupling in skeletal muscle by UCP1 augments energy expenditure and glutathione content while mitigating ROS production. Am J Physiol Endocrinol Metab 2013 0.86
47 Absence of uncoupling protein-3 leads to greater activation of an adenine nucleotide translocase-mediated proton conductance in skeletal muscle mitochondria from calorie restricted mice. Biochim Biophys Acta 2010 0.84
48 Implications of mitochondrial uncoupling in skeletal muscle in the development and treatment of obesity. FEBS J 2013 0.84
49 Influence of mitochondrial membrane fatty acid composition on proton leak and H2O2 production in liver. Comp Biochem Physiol B Biochem Mol Biol 2005 0.84
50 The role of mitochondrial uncoupling in 3,4-methylenedioxymethamphetamine-mediated skeletal muscle hyperthermia and rhabdomyolysis. J Pharmacol Exp Ther 2005 0.83
51 Mutated ATP synthase induces oxidative stress and impaired insulin secretion in beta-cells of female BHE/cdb rats. Diabetes Metab Res Rev 2008 0.83
52 Increased proton leak and SOD2 expression in myotubes from obese non-diabetic subjects with a family history of type 2 diabetes. Biochim Biophys Acta 2013 0.82
53 Calorie restriction in mice overexpressing UCP3: evidence that prior mitochondrial uncoupling alters response. Exp Gerontol 2012 0.81
54 Fasting and postprandial total ghrelin remain unchanged after short-term energy restriction. J Clin Endocrinol Metab 2004 0.80
55 Oxidative status of muscle is determined by p107 regulation of PGC-1alpha. J Cell Biol 2010 0.80
56 Cellular metabolism as a basis for immune privilege. J Immune Based Ther Vaccines 2006 0.79
57 Skeletal muscle mitochondrial energetics in obesity and type 2 diabetes mellitus: endocrine aspects. Best Pract Res Clin Endocrinol Metab 2012 0.79
58 Effects of nitric oxide donors on cybrids harbouring the mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) A3243G mitochondrial DNA mutation. Biochem J 2005 0.78
59 Reduced in vivo phosphodiesterase-4 response to acute noradrenaline challenge in diet-induced obese rats. Can J Physiol Pharmacol 2009 0.77
60 Chronic AMPK activity dysregulation produces myocardial insulin resistance in the human Arg302Gln-PRKAG2 glycogen storage disease mouse model. EJNMMI Res 2013 0.76
61 Lower mitochondrial proton leak and decreased glutathione redox in primary muscle cells of obese diet-resistant versus diet-sensitive humans. J Clin Endocrinol Metab 2014 0.76
62 Ablation of LMO4 in glutamatergic neurons impairs leptin control of fat metabolism. Cell Mol Life Sci 2011 0.75
63 Enhanced glucose homeostasis in BHE/cdb rats with mutated ATP synthase. Mitochondrion 2013 0.75