| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Transcriptional control of brown fat determination by PRDM16.
|
Cell Metab
|
2007
|
6.79
|
|
2
|
Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss.
|
Diabetes
|
2005
|
5.68
|
|
3
|
Acquirement of brown fat cell features by human white adipocytes.
|
J Biol Chem
|
2003
|
3.05
|
|
4
|
Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects.
|
FASEB J
|
2004
|
2.82
|
|
5
|
Lipolysis and lipid mobilization in human adipose tissue.
|
Prog Lipid Res
|
2009
|
2.57
|
|
6
|
Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity.
|
Genome Biol
|
2008
|
2.22
|
|
7
|
Contribution of adipose triglyceride lipase and hormone-sensitive lipase to lipolysis in hMADS adipocytes.
|
J Biol Chem
|
2009
|
1.93
|
|
8
|
Worsening of obesity and metabolic status yields similar molecular adaptations in human subcutaneous and visceral adipose tissue: decreased metabolism and increased immune response.
|
J Clin Endocrinol Metab
|
2010
|
1.92
|
|
9
|
Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass.
|
PLoS Biol
|
2013
|
1.87
|
|
10
|
CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance.
|
Cell Metab
|
2009
|
1.68
|
|
11
|
Macrophages and adipocytes in human obesity: adipose tissue gene expression and insulin sensitivity during calorie restriction and weight stabilization.
|
Diabetes
|
2009
|
1.59
|
|
12
|
beta3-Adrenergic stimulation produces a decrease of cardiac contractility ex vivo in mice overexpressing the human beta3-adrenergic receptor.
|
Cardiovasc Res
|
2003
|
1.55
|
|
13
|
Adipose triglyceride lipase and hormone-sensitive lipase protein expression is decreased in the obese insulin-resistant state.
|
J Clin Endocrinol Metab
|
2007
|
1.54
|
|
14
|
Effects of TCF7L2 polymorphisms on obesity in European populations.
|
Obesity (Silver Spring)
|
2008
|
1.49
|
|
15
|
In vivo epinephrine-mediated regulation of gene expression in human skeletal muscle.
|
J Clin Endocrinol Metab
|
2004
|
1.49
|
|
16
|
Altered skeletal muscle lipase expression and activity contribute to insulin resistance in humans.
|
Diabetes
|
2011
|
1.45
|
|
17
|
Adipose tissue lipolysis.
|
Curr Opin Clin Nutr Metab Care
|
2010
|
1.34
|
|
18
|
In vivo regulation of human skeletal muscle gene expression by thyroid hormone.
|
Genome Res
|
2002
|
1.33
|
|
19
|
Influence of gender, obesity, and muscle lipase activity on intramyocellular lipids in sedentary individuals.
|
J Clin Endocrinol Metab
|
2009
|
1.32
|
|
20
|
Natriuretic peptides enhance the oxidative capacity of human skeletal muscle.
|
J Clin Invest
|
2012
|
1.32
|
|
21
|
Cdk4 promotes adipogenesis through PPARgamma activation.
|
Cell Metab
|
2005
|
1.31
|
|
22
|
Effect of aerobic training on plasma levels and subcutaneous abdominal adipose tissue gene expression of adiponectin, leptin, interleukin 6, and tumor necrosis factor alpha in obese women.
|
Metabolism
|
2006
|
1.31
|
|
23
|
WISP2 regulates preadipocyte commitment and PPARγ activation by BMP4.
|
Proc Natl Acad Sci U S A
|
2013
|
1.30
|
|
24
|
NF-kappaB is important for TNF-alpha-induced lipolysis in human adipocytes.
|
J Lipid Res
|
2007
|
1.30
|
|
25
|
Comparative studies of the role of hormone-sensitive lipase and adipose triglyceride lipase in human fat cell lipolysis.
|
Am J Physiol Endocrinol Metab
|
2007
|
1.29
|
|
26
|
Cathepsin S, a novel biomarker of adiposity: relevance to atherogenesis.
|
FASEB J
|
2005
|
1.27
|
|
27
|
The case for strategic international alliances to harness nutritional genomics for public and personal health.
|
Br J Nutr
|
2005
|
1.24
|
|
28
|
Adiponutrin: A new gene regulated by energy balance in human adipose tissue.
|
J Clin Endocrinol Metab
|
2004
|
1.23
|
|
29
|
Fat oxidation before and after a high fat load in the obese insulin-resistant state.
|
J Clin Endocrinol Metab
|
2006
|
1.21
|
|
30
|
Effects of different hypocaloric diets on protein secretion from adipose tissue of obese women.
|
Diabetes
|
2004
|
1.20
|
|
31
|
Conversion from white to brown adipocytes: a strategy for the control of fat mass?
|
Trends Endocrinol Metab
|
2003
|
1.19
|
|
32
|
Regulation of human adipocyte gene expression by thyroid hormone.
|
J Clin Endocrinol Metab
|
2002
|
1.10
|
|
33
|
Peroxisome proliferator-activated receptor-alpha control of lipid and glucose metabolism in human white adipocytes.
|
Endocrinology
|
2009
|
1.03
|
|
34
|
Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance.
|
Nat Med
|
2013
|
1.02
|
|
35
|
A role for adipocyte-derived lipopolysaccharide-binding protein in inflammation- and obesity-associated adipose tissue dysfunction.
|
Diabetologia
|
2013
|
1.00
|
|
36
|
Plasma levels and adipose tissue messenger ribonucleic acid expression of retinol-binding protein 4 are reduced during calorie restriction in obese subjects but are not related to diet-induced changes in insulin sensitivity.
|
J Clin Endocrinol Metab
|
2007
|
1.00
|
|
37
|
The role of neutral lipases in human adipose tissue lipolysis.
|
Curr Opin Lipidol
|
2007
|
0.99
|
|
38
|
The transcriptional coactivator peroxisome proliferator activated receptor (PPAR)gamma coactivator-1 alpha and the nuclear receptor PPAR alpha control the expression of glycerol kinase and metabolism genes independently of PPAR gamma activation in human white adipocytes.
|
Diabetes
|
2007
|
0.99
|
|
39
|
High-fat diet-mediated lipotoxicity and insulin resistance is related to impaired lipase expression in mouse skeletal muscle.
|
Endocrinology
|
2013
|
0.99
|
|
40
|
Dynamics of skeletal muscle lipid pools.
|
Trends Endocrinol Metab
|
2013
|
0.99
|
|
41
|
Hormone-sensitive lipase is a cholesterol esterase of the intestinal mucosa.
|
J Biol Chem
|
2002
|
0.98
|
|
42
|
Liver X receptor (LXR) regulates human adipocyte lipolysis.
|
J Biol Chem
|
2010
|
0.97
|
|
43
|
Adipose tissue transcriptome reflects variations between subjects with continued weight loss and subjects regaining weight 6 mo after caloric restriction independent of energy intake.
|
Am J Clin Nutr
|
2010
|
0.97
|
|
44
|
Genetic polymorphisms and weight loss in obesity: a randomised trial of hypo-energetic high- versus low-fat diets.
|
PLoS Clin Trials
|
2006
|
0.97
|
|
45
|
Expression of human hormone-sensitive lipase in white adipose tissue of transgenic mice increases lipase activity but does not enhance in vitro lipolysis.
|
J Lipid Res
|
2003
|
0.96
|
|
46
|
Contribution of energy restriction and macronutrient composition to changes in adipose tissue gene expression during dietary weight-loss programs in obese women.
|
J Clin Endocrinol Metab
|
2008
|
0.96
|
|
47
|
A distinct adipose tissue gene expression response to caloric restriction predicts 6-mo weight maintenance in obese subjects.
|
Am J Clin Nutr
|
2011
|
0.95
|
|
48
|
Evidence for an important role of CIDEA in human cancer cachexia.
|
Cancer Res
|
2008
|
0.94
|
|
49
|
Regulation of adipose tissue lipolysis revisited.
|
Proc Nutr Soc
|
2009
|
0.93
|
|
50
|
Endurance exercise training up-regulates lipolytic proteins and reduces triglyceride content in skeletal muscle of obese subjects.
|
J Clin Endocrinol Metab
|
2013
|
0.93
|
|
51
|
Chronic TNFalpha and cAMP pre-treatment of human adipocytes alter HSL, ATGL and perilipin to regulate basal and stimulated lipolysis.
|
FEBS Lett
|
2009
|
0.92
|
|
52
|
In vitro brown and "brite"/"beige" adipogenesis: human cellular models and molecular aspects.
|
Biochim Biophys Acta
|
2012
|
0.91
|
|
53
|
Cyclin G2 regulates adipogenesis through PPAR gamma coactivation.
|
Endocrinology
|
2010
|
0.91
|
|
54
|
Genetic association and gene expression analysis identify FGFR1 as a new susceptibility gene for human obesity.
|
J Clin Endocrinol Metab
|
2011
|
0.91
|
|
55
|
Transcriptional regulation of adipocyte hormone-sensitive lipase by glucose.
|
Diabetes
|
2002
|
0.91
|
|
56
|
Determinants of human adipose tissue gene expression: impact of diet, sex, metabolic status, and cis genetic regulation.
|
PLoS Genet
|
2012
|
0.91
|
|
57
|
Adiponectin gene expression in subcutaneous adipose tissue of obese women in response to short-term very low calorie diet and refeeding.
|
J Clin Endocrinol Metab
|
2003
|
0.91
|
|
58
|
Weight loss improves the adipogenic capacity of human preadipocytes and modulates their secretory profile.
|
Diabetes
|
2013
|
0.90
|
|
59
|
TFAP2B influences the effect of dietary fat on weight loss under energy restriction.
|
PLoS One
|
2012
|
0.89
|
|
60
|
Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity.
|
Diabetes
|
2013
|
0.89
|
|
61
|
Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase.
|
Circulation
|
2013
|
0.89
|
|
62
|
The testicular form of hormone-sensitive lipase HSLtes confers rescue of male infertility in HSL-deficient mice.
|
J Biol Chem
|
2004
|
0.89
|
|
63
|
Secretion of adiponectin multimeric complexes from adipose tissue explants is not modified by very low calorie diet.
|
Eur J Endocrinol
|
2009
|
0.89
|
|
64
|
Regulation of skeletal muscle lipolysis and oxidative metabolism by the co-lipase CGI-58.
|
J Lipid Res
|
2012
|
0.89
|
|
65
|
Skeletal muscle lipase content and activity in obesity and type 2 diabetes.
|
J Clin Endocrinol Metab
|
2010
|
0.89
|
|
66
|
ApoB100-LDL acts as a metabolic signal from liver to peripheral fat causing inhibition of lipolysis in adipocytes.
|
PLoS One
|
2008
|
0.89
|
|
67
|
Secretory products of guinea pig epicardial fat induce insulin resistance and impair primary adult rat cardiomyocyte function.
|
J Cell Mol Med
|
2011
|
0.89
|
|
68
|
Adipose tissue secretion and expression of adipocyte-produced and stromavascular fraction-produced adipokines vary during multiple phases of weight-reducing dietary intervention in obese women.
|
J Clin Endocrinol Metab
|
2012
|
0.88
|
|
69
|
TCF7L2 rs7903146-macronutrient interaction in obese individuals' responses to a 10-wk randomized hypoenergetic diet.
|
Am J Clin Nutr
|
2009
|
0.88
|
|
70
|
Understanding adipose tissue development from transgenic animal models.
|
J Lipid Res
|
2002
|
0.88
|
|
71
|
Adipose gene expression prior to weight loss can differentiate and weakly predict dietary responders.
|
PLoS One
|
2007
|
0.87
|
|
72
|
Obesity-related polymorphisms and their associations with the ability to regulate fat oxidation in obese Europeans: the NUGENOB study.
|
Obesity (Silver Spring)
|
2009
|
0.87
|
|
73
|
Multiple effects of a short-term dexamethasone treatment in human skeletal muscle and adipose tissue.
|
Physiol Genomics
|
2011
|
0.86
|
|
74
|
Profiling of adipokines secreted from human subcutaneous adipose tissue in response to PPAR agonists.
|
Biochem Biophys Res Commun
|
2007
|
0.86
|
|
75
|
Characterization of a novel testicular form of human hormone-sensitive lipase.
|
Biochem Biophys Res Commun
|
2002
|
0.85
|
|
76
|
Adiponectin gene expression and plasma values in obese women during very-low-calorie diet. Relationship with cardiovascular risk factors and insulin resistance.
|
J Clin Endocrinol Metab
|
2004
|
0.84
|
|
77
|
A novel hormone-sensitive lipase isoform expressed in pancreatic beta-cells.
|
J Biol Chem
|
2003
|
0.84
|
|
78
|
Impaired fat-induced thermogenesis in obese subjects: the NUGENOB study.
|
Obesity (Silver Spring)
|
2007
|
0.84
|
|
79
|
Genotype-by-nutrient interactions assessed in European obese women. A case-only study.
|
Eur J Nutr
|
2006
|
0.84
|
|
80
|
Effect of thyroid hormone on gene expression.
|
Curr Opin Clin Nutr Metab Care
|
2003
|
0.83
|
|
81
|
A "futile cycle" induced by thiazolidinediones in human adipose tissue?
|
Nat Med
|
2003
|
0.83
|
|
82
|
Analyses of single nucleotide polymorphisms in selected nutrient-sensitive genes in weight-regain prevention: the DIOGENES study.
|
Am J Clin Nutr
|
2012
|
0.83
|
|
83
|
Enhanced glucose metabolism is preserved in cultured primary myotubes from obese donors in response to exercise training.
|
J Clin Endocrinol Metab
|
2013
|
0.82
|
|
84
|
The transcriptional co-activator PGC-1alpha up regulates apelin in human and mouse adipocytes.
|
Regul Pept
|
2008
|
0.82
|
|
85
|
Effects of 3 diets with various calcium contents on 24-h energy expenditure, fat oxidation, and adipose tissue message RNA expression of lipid metabolism-related proteins.
|
Am J Clin Nutr
|
2005
|
0.81
|
|
86
|
The effects of increasing serum calcitriol on energy and fat metabolism and gene expression.
|
Obesity (Silver Spring)
|
2006
|
0.81
|
|
87
|
Gene expression profiling of human skeletal muscle in response to stabilized weight loss.
|
Am J Clin Nutr
|
2008
|
0.81
|
|
88
|
Norepinephrine induces lipolysis in beta1/beta2/beta3-adrenoceptor knockout mice.
|
Mol Pharmacol
|
2005
|
0.80
|
|
89
|
CIDEA interacts with liver X receptors in white fat cells.
|
FEBS Lett
|
2011
|
0.80
|
|
90
|
Lipid mobilization in subcutaneous adipose tissue during exercise in lean and obese humans. Roles of insulin and natriuretic peptides.
|
Am J Physiol Endocrinol Metab
|
2010
|
0.80
|
|
91
|
Influence of SNPs in nutrient-sensitive candidate genes and gene-diet interactions on blood lipids: the DiOGenes study.
|
Br J Nutr
|
2013
|
0.80
|
|
92
|
Soluble CD163 is associated with CD163 mRNA expression in adipose tissue and with insulin sensitivity in steady-state condition but not in response to calorie restriction.
|
J Clin Endocrinol Metab
|
2014
|
0.79
|
|
93
|
Metabolic syndrome, circulating RBP4, testosterone, and SHBG predict weight regain at 6 months after weight loss in men.
|
Obesity (Silver Spring)
|
2013
|
0.79
|
|
94
|
α-lipoic acid reduces fatty acid esterification and lipogenesis in adipocytes from overweight/obese subjects.
|
Obesity (Silver Spring)
|
2014
|
0.79
|
|
95
|
MAFB as a novel regulator of human adipose tissue inflammation.
|
Diabetologia
|
2015
|
0.79
|
|
96
|
Effect of hyperinsulinemia and very-low-calorie diet on interstitial cytokine levels in subcutaneous adipose tissue of obese women.
|
Am J Physiol Endocrinol Metab
|
2009
|
0.79
|
|
97
|
The presence of a catalytically inactive form of hormone-sensitive lipase is associated with decreased lipolysis in abdominal subcutaneous adipose tissue of obese subjects.
|
Diabetes
|
2003
|
0.78
|
|
98
|
Catecholamine and insulin control of lipolysis in subcutaneous adipose tissue during long-term diet-induced weight loss in obese women.
|
Am J Physiol Endocrinol Metab
|
2011
|
0.78
|
|
99
|
[Fatty acid mobilization and their use in adipose tissue].
|
J Soc Biol
|
2006
|
0.78
|
|
100
|
Influence of lipolysis and fatty acid availability on fuel selection during exercise.
|
J Physiol Biochem
|
2013
|
0.78
|
|
101
|
Hidden variant of ChREBP in fat links lipogenesis to insulin sensitivity.
|
Cell Metab
|
2012
|
0.77
|
|
102
|
Regiocontrolled syntheses of FAHFAs and LC-MS/MS differentiation of regioisomers.
|
Org Biomol Chem
|
2016
|
0.77
|
|
103
|
Pro-fibrotic activity of lysophosphatidic acid in adipose tissue: in vivo and in vitro evidence.
|
Biochim Biophys Acta
|
2013
|
0.77
|
|
104
|
Dietary factors impact on the association between CTSS variants and obesity related traits.
|
PLoS One
|
2012
|
0.76
|
|
105
|
Positive interaction between prebiotics and thiazolidinedione treatment on adiposity in diet-induced obese mice.
|
Obesity (Silver Spring)
|
2014
|
0.76
|
|
106
|
Comment on: Sitnick et al. Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity. Diabetes 2013;62:3350-3361.
|
Diabetes
|
2013
|
0.75
|
|
107
|
Adipose tissue lipases and lipolysis.
|
Endocrinol Nutr
|
2013
|
0.75
|
|
108
|
[PGC-1alpha, a transcriptional coactivator involved in metabolism].
|
Med Sci (Paris)
|
2005
|
0.75
|
|
109
|
Change in proportional protein intake in a 10-week energy-restricted low- or high-fat diet, in relation to changes in body size and metabolic factors.
|
Obes Facts
|
2013
|
0.75
|