Published in Neuropharmacology on December 24, 2009
Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression. J Clin Invest (2012) 1.51
Validity of acute and chronic tactile sensory testing after spinal cord injury in rats. Exp Neurol (2010) 1.05
Combination Drug Therapy for Pain following Chronic Spinal Cord Injury. Pain Res Treat (2012) 0.87
Activation of spinal and supraspinal cannabinoid-1 receptors leads to antinociception in a rat model of neuropathic spinal cord injury pain. Brain Res (2011) 0.84
Acetaminophen modulation of hydrocodone reward in rats. Pharmacol Biochem Behav (2011) 0.83
Fatty acid amide hydrolase (FAAH) inhibitors exert pharmacological effects, but lack antinociceptive efficacy in rats with neuropathic spinal cord injury pain. PLoS One (2014) 0.79
Combinations of intrathecal gamma-amino-butyrate receptor agonists and N-methyl-d-aspartate receptor antagonists in rats with neuropathic spinal cord injury pain. Eur J Pharmacol (2012) 0.78
Activation of cannabinoid CB2 receptors reduces hyperalgesia in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis. Neurosci Lett (2015) 0.76
Cannabinoid system and cyclooxygenases inhibitors. J Med Life (2011) 0.75
Quantitative assessment of tactile allodynia in the rat paw. J Neurosci Methods (1994) 23.05
New uses for old drugs. Nature (2007) 5.86
Drug synergism: its detection and applications. J Pharmacol Exp Ther (2001) 4.11
Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic. J Pharmacol Exp Ther (1992) 3.58
Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia. Pain (2004) 2.94
Pharmacological profile of the selective FAAH inhibitor KDS-4103 (URB597). CNS Drug Rev (2006) 2.25
Pharmacotherapy of chronic pain: a synthesis of recommendations from systematic reviews. Gen Hosp Psychiatry (2009) 2.23
The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice. J Pharmacol Exp Ther (2007) 1.96
Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system. J Biol Chem (2005) 1.88
Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models. Br J Pharmacol (2006) 1.83
Peripheral nerve injury induces cannabinoid receptor 2 protein expression in rat sensory neurons. Neuroscience (2005) 1.76
Mechanisms of chronic central neuropathic pain after spinal cord injury. Brain Res Rev (2008) 1.69
Paracetamol: new vistas of an old drug. CNS Drug Rev (2007) 1.63
Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain. Pain (2006) 1.61
Cannabis, pain, and sleep: lessons from therapeutic clinical trials of Sativex, a cannabis-based medicine. Chem Biodivers (2007) 1.57
Interactions between drugs and occupied receptors. Pharmacol Ther (2006) 1.53
Capsaicin (TRPV1 Agonist) therapy for pain relief: farewell or revival? Clin J Pain (2008) 1.47
CB2 cannabinoid receptor mediation of antinociception. Pain (2006) 1.47
Statistical analysis of drug-drug and site-site interactions with isobolograms. Life Sci (1989) 1.43
Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain: a randomized controlled trial. JAMA (2003) 1.41
The analgesic effects of R(+)-WIN 55,212-2 mesylate, a high affinity cannabinoid agonist, in a rat model of neuropathic pain. Neurosci Lett (1997) 1.39
Treatments for chronic pain in persons with spinal cord injury: A survey study. J Spinal Cord Med (2006) 1.33
Spinal cord injury pain--mechanisms and treatment. Eur J Neurol (2004) 1.31
Transcriptional profiling of spinal cord injury-induced central neuropathic pain. J Neurochem (2005) 1.31
Therapeutic misadventure with paracetamol: fact or fiction? Am J Ther (2000) 1.27
Segmental organization of spinal reflexes mediating autonomic dysreflexia after spinal cord injury. Prog Brain Res (2006) 1.19
Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: involvement of cytokine/chemokines and PMN. J Leukoc Biol (2003) 1.17
Spinal and peripheral mechanisms of cannabinoid antinociception: behavioral, neurophysiological and neuroanatomical perspectives. Chem Phys Lipids (2002) 1.17
Prevalence of chronic pain after traumatic spinal cord injury: a systematic review. J Rehabil Res Dev (2009) 1.16
Cancer pain and analgesia. Ann N Y Acad Sci (2008) 1.14
Modulation of morphine antinociception by peripheral [Leu5]enkephalin: a synergistic interaction. Eur J Pharmacol (1990) 1.14
Types and effectiveness of treatments used by people with chronic pain associated with spinal cord injuries: influence of pain and psychosocial characteristics. Spinal Cord (2003) 1.12
Attenuation of mechanical allodynia by clinically utilized drugs in a rat chemotherapy-induced neuropathic pain model. Pain (2004) 1.12
Pharmacological characterization of the chronic constriction injury model of neuropathic pain. Eur J Pharmacol (2004) 1.11
Naloxone-reversible antinociception by paracetamol in the rat. J Pharmacol Exp Ther (1997) 1.11
Modulation of neuropathic and inflammatory pain by the endocannabinoid transport inhibitor AM404 [N-(4-hydroxyphenyl)-eicosa-5,8,11,14-tetraenamide]. J Pharmacol Exp Ther (2006) 1.11
Endocannabinoid and serotonergic systems are needed for acetaminophen-induced analgesia. Pain (2008) 1.11
The endocannabinoid system is modulated in response to spinal cord injury in rats. Neurobiol Dis (2008) 1.10
Differential blockade of the antinociceptive effects of centrally administered cannabinoids by SR141716A. J Pharmacol Exp Ther (1998) 1.08
Testing for synergism over a range of fixed ratio drug combinations: replacing the isobologram. Life Sci (1996) 1.08
Combination pharmacotherapy for neuropathic pain: current evidence and future directions. Expert Rev Neurother (2005) 1.07
Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission. J Neurochem (1998) 1.06
Discovery of "self-synergistic" spinal/supraspinal antinociception produced by acetaminophen (paracetamol). J Pharmacol Exp Ther (2000) 1.04
The enhancement of morphine antinociception in mice by delta9-tetrahydrocannabinol. Pharmacol Biochem Behav (1998) 1.04
A proposed algorithm for the management of pain following spinal cord injury. Spinal Cord (2006) 1.03
Behavioral characterization and effect of clinical drugs in a rat model of pain following spinal cord compression. Brain Res (2007) 1.02
Spinal cord injury pain: spinal and supraspinal mechanisms. J Rehabil Res Dev (2009) 1.02
Species differences in hepatic glutathione depletion, covalent binding and hepatic necrosis after acetaminophen. Life Sci (1974) 1.02
Tramadol in neuropathic pain after spinal cord injury: a randomized, double-blind, placebo-controlled trial. Clin J Pain (2009) 1.00
The mechanosensitivity of spinal sensory neurons following intraspinal injections of quisqualic acid in the rat. Neurosci Lett (1993) 0.99
The local antinociceptive effects of paracetamol in neuropathic pain are mediated by cannabinoid receptors. Eur J Pharmacol (2007) 0.99
Synergistic and additive interactions of the cannabinoid agonist CP55,940 with mu opioid receptor and alpha2-adrenoceptor agonists in acute pain models in mice. Br J Pharmacol (2005) 0.99
Actions of tramadol on micturition in awake, freely moving rats. Br J Pharmacol (2003) 0.96
The mu-opioid receptor agonist morphine, but not agonists at delta- or kappa-opioid receptors, induces peripheral antinociception mediated by cannabinoid receptors. Br J Pharmacol (2008) 0.95
Modulation of opioids via protection of anandamide degradation by fatty acid amide hydrolase. Eur J Pharmacol (2008) 0.93
Therapeutic doses of codeine have no effect on acetaminophen clearance or metabolism. Eur J Clin Pharmacol (1988) 0.92
Central antinociception induced by mu-opioid receptor agonist morphine, but not delta- or kappa-, is mediated by cannabinoid CB1 receptor. Br J Pharmacol (2009) 0.92
Combination strategies for pain management. Expert Opin Pharmacother (2003) 0.91
Antioxidative and hepatoprotective effects of magnolol on acetaminophen-induced liver damage in rats. Arch Pharm Res (2009) 0.91
The post-operative analgesic effects of a combination of gabapentin and paracetamol in patients undergoing abdominal hysterectomy: a randomized clinical trial. Acta Anaesthesiol Scand (2007) 0.90
Antinociceptive effect of cannabinoid agonist WIN 55,212-2 in rats with a spinal cord injury. Exp Neurol (2006) 0.90
Topical cannabinoid enhances topical morphine antinociception. Pain (2003) 0.89
Antihyperalgesic effects of vanilloid-1 and bradykinin-1 receptor antagonists following spinal cord injury in rats. J Neurosurg Spine (2007) 0.88
Tramadol/paracetamol. Drugs (2003) 0.87
Change of vanilloid receptor 1 following neuromodulation in rats with spinal cord injury. J Surg Res (2002) 0.87
Changes in properties of spinal dorsal horn neurons and their sensitivity to morphine after spinal cord injury in the rat. Anesthesiology (2005) 0.84
Management of pain in persons with spinal cord injury. J Spinal Cord Med (1997) 0.84
Effects of acetaminophen on monoaminergic systems in the rat central nervous system. Naunyn Schmiedebergs Arch Pharmacol (2001) 0.83
Drug interactions in human neuropathic pain pharmacotherapy. Pain (1997) 0.82
Lack of effect of paracetamol on the pharmacokinetics and metabolism of codeine in man. Eur J Clin Pharmacol (1991) 0.81
Ultra-low dose ketamine and memantine treatment for pain in an opioid-tolerant oncology patient. Anesth Analg (2008) 0.81
Further evidence for a peripheral component in the enhanced antinociceptive effect of systemic morphine in mononeuropathic rats: involvement of kappa-, but not delta-opioid receptors. Eur J Pharmacol (1996) 0.80
Sex- and age-dependent acetaminophen hepato- and nephrotoxicity in Sprague-Dawley rats: role of tissue accumulation, nonprotein sulfhydryl depletion, and covalent binding. Fundam Appl Toxicol (1996) 0.80
Use of capsaicin in the treatment of radicular pain in spinal cord injury. J Spinal Cord Med (2000) 0.80
Unexpected and pronounced antinociceptive synergy between spinal acetaminophen (paracetamol) and phentolamine. Eur J Pharmacol (2001) 0.79
Altered antinociceptive efficacy of tramadol over time in rats with painful peripheral neuropathy. Eur J Pharmacol (2006) 0.79
Analysis of interaction between etoricoxib and tramadol against mechanical hyperalgesia of spinal cord injury in rats. Life Sci (2005) 0.78
The effect of cannabinoid receptor antagonism with SR141716A on antinociception induced by cocaine and the NMDA receptor antagonist, MK-801. Brain Res Bull (2003) 0.77
The antinociceptive effect of intrathecal administration of epibatidine with clonidine or neostigmine in the formalin test in rats. Pain (2001) 0.77
Pain: a multidimensional problem of national priority. J Rehabil Res Dev (2009) 0.76
Widespread cellular proliferation and focal neurogenesis after traumatic brain injury in the rat. Restor Neurol Neurosci (2007) 1.30
Transgenic inhibition of glial NF-kappa B reduces pain behavior and inflammation after peripheral nerve injury. Pain (2010) 1.11
Behavioral characterization and effect of clinical drugs in a rat model of pain following spinal cord compression. Brain Res (2007) 1.02
Antinociceptive effect of riluzole in rats with neuropathic spinal cord injury pain. J Neurotrauma (2010) 0.92
Differential efficacy of intrathecal NMDA receptor antagonists on inflammatory mechanical and thermal hyperalgesia in rats. Eur J Pharmacol (2003) 0.90
Antinociceptive effect of cannabinoid agonist WIN 55,212-2 in rats with a spinal cord injury. Exp Neurol (2006) 0.90
Transgenic glial nuclear factor-kappa B inhibition decreases formalin pain in mice. Neuroreport (2007) 0.89
Antinociceptive effects of the marine snail peptides conantokin-G and conotoxin MVIIA alone and in combination in rat models of pain. Neuropharmacology (2008) 0.89
Combination Drug Therapy for Pain following Chronic Spinal Cord Injury. Pain Res Treat (2012) 0.87
Antinociceptive effect of ambroxol in rats with neuropathic spinal cord injury pain. Pharmacol Biochem Behav (2010) 0.87
TrkC overexpression enhances survival and migration of neural stem cell transplants in the rat spinal cord. Cell Transplant (2002) 0.85
Intraspinal transplantation of GABAergic neural progenitors attenuates neuropathic pain in rats: a pharmacologic and neurophysiological evaluation. Exp Neurol (2011) 0.85
Activation of spinal and supraspinal cannabinoid-1 receptors leads to antinociception in a rat model of neuropathic spinal cord injury pain. Brain Res (2011) 0.84
NMDA antagonist peptide supplementation enhances pain alleviation by adrenal medullary transplants. Cell Transplant (2005) 0.83
Enhancement of morphine antinociception with the peptide N-methyl-D-aspartate receptor antagonist [Ser1]-histogranin in the rat formalin test. Brain Res (2006) 0.82
The antinociceptive effect of the asthma drug ibudilast in rat models of peripheral and central neuropathic pain. J Neurotrauma (2011) 0.82
An Intensive Locomotor Training Paradigm Improves Neuropathic Pain following Spinal Cord Compression Injury in Rats. J Neurotrauma (2015) 0.80
Inhibition by the chromaffin cell-derived peptide serine-histogranin in the rat's dorsal horn. Neurosci Lett (2007) 0.80
Prolonged nociceptive responses to hind paw formalin injection in rats with a spinal cord injury. Neurosci Lett (2008) 0.80
Predifferentiated GABAergic neural precursor transplants for alleviation of dysesthetic central pain following excitotoxic spinal cord injury. Front Physiol (2012) 0.80
Sustained antinociceptive effect of cannabinoid receptor agonist WIN 55,212-2 over time in rat model of neuropathic spinal cord injury pain. J Rehabil Res Dev (2009) 0.80
Enhanced viability and neuronal differentiation of neural progenitors by chromaffin cell co-culture. Brain Res Dev Brain Res (2002) 0.80
Selective antihyperalgesic effect of [Ser1] histogranin on complete Freund's adjuvant-induced hyperalgesia in rats. Pain (2002) 0.79
Improved neural progenitor cell survival when cografted with chromaffin cells in the rat striatum. Exp Neurol (2004) 0.79
Adrenal medullary transplants reduce formalin-evoked c-fos expression in the rat spinal cord. Brain Res (2002) 0.79
FK506 reduces the severity of cutaneous hypersensitivity in rats with a spinal cord contusion. Neurosci Res (2007) 0.79
Combined extrinsic and intrinsic manipulations exert complementary neuronal enrichment in embryonic rat neural precursor cultures: an in vitro and in vivo analysis. J Comp Neurol (2009) 0.79
Sustained analgesic peptide secretion and cell labeling using a novel genetic modification. Cell Transplant (2008) 0.79
Altered antinociceptive efficacy of tramadol over time in rats with painful peripheral neuropathy. Eur J Pharmacol (2006) 0.79
Combinations of intrathecal gamma-amino-butyrate receptor agonists and N-methyl-d-aspartate receptor antagonists in rats with neuropathic spinal cord injury pain. Eur J Pharmacol (2012) 0.78
Centrally mediated antinociceptive effects of cannabinoid receptor ligands in rat models of nociception. Pharmacol Biochem Behav (2011) 0.77
Expansion of formalin-evoked Fos-immunoreactivity in rats with a spinal cord injury. Neurosci Res (2007) 0.77
Glial NF-κB inhibition alters neuropeptide expression after sciatic nerve injury in mice. Brain Res (2011) 0.77
Enhanced antinociception by nicotinic receptor agonist epibatidine and adrenal medullary transplants in the spinal subarachnoid space. Neuropharmacology (2004) 0.76
Deafferentation pain resulting from cervical posterior rhizotomy is alleviated by chromaffin cell transplants into the rat spinal subarachnoid space. Neurosurgery (2007) 0.75
Spinal subarachnoid adrenal medullary transplants reduce hind paw swelling and peripheral nerve transport following formalin injection in rats. Brain Res (2008) 0.75
Recombinant neural progenitor transplants in the spinal dorsal horn alleviate chronic central neuropathic pain. Pain (2016) 0.75
Dissociated human embryonic and fetal adrenal glands in neural stem cell culture system: open fate for neuronal, nonneuronal, and chromaffin lineages? Ann N Y Acad Sci (2002) 0.75
Use of naturally occurring peptides for neuropathic spinal cord injury pain. Curr Protein Pept Sci (2013) 0.75
Analgesic Effect of Recombinant GABAergic Cells in a Model of Peripheral Neuropathic Pain. Cell Transplant (2016) 0.75
Direct cell-cell contact required for neurotrophic effect of chromaffin cells on neural progenitor cells. Brain Res Dev Brain Res (2003) 0.75
ALLEVIATION OF PAIN IN CANCER PATIENTS BY ADRENAL MEDULLARY TRANSPLANTS IN THE SPINAL SUBARACHNOID SPACE. Cell Transplant (1993) 0.75