L Gabriel Navar

Author PubWeight™ 120.99‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease. Pharmacol Rev 2007 6.79
2 Urinary excretion of angiotensinogen reflects intrarenal angiotensinogen production. Kidney Int 2002 3.23
3 Urinary angiotensinogen as an indicator of intrarenal Angiotensin status in hypertension. Hypertension 2003 2.99
4 AT1 receptor mediated augmentation of intrarenal angiotensinogen in angiotensin II-dependent hypertension. Hypertension 2004 2.86
5 Enhancement of collecting duct renin in angiotensin II-dependent hypertensive rats. Hypertension 2004 2.54
6 The absence of intrarenal ACE protects against hypertension. J Clin Invest 2013 2.31
7 Ang II accumulation in rat renal endosomes during Ang II-induced hypertension: role of AT(1) receptor. Hypertension 2002 2.11
8 Collecting duct renin is upregulated in both kidneys of 2-kidney, 1-clip goldblatt hypertensive rats. Hypertension 2008 2.01
9 Novel sandwich ELISA for human angiotensinogen. Am J Physiol Renal Physiol 2007 1.99
10 Urinary angiotensinogen as a novel biomarker of the intrarenal renin-angiotensin system status in hypertensive patients. Hypertension 2008 1.99
11 Genetic deletion of AT1a receptors attenuates intracellular accumulation of ANG II in the kidney of AT1a receptor-deficient mice. Am J Physiol Renal Physiol 2007 1.99
12 Enhancement of intrarenal angiotensinogen in Dahl salt-sensitive rats on high salt diet. Hypertension 2003 1.89
13 Kidney-specific enhancement of ANG II stimulates endogenous intrarenal angiotensinogen in gene-targeted mice. Am J Physiol Renal Physiol 2007 1.87
14 AT1 receptor-mediated enhancement of collecting duct renin in angiotensin II-dependent hypertensive rats. Am J Physiol Renal Physiol 2005 1.84
15 Enhanced distal nephron sodium reabsorption in chronic angiotensin II-infused mice. Hypertension 2009 1.83
16 Sustained renal interstitial macrophage infiltration following chronic angiotensin II infusions. Am J Physiol Renal Physiol 2006 1.83
17 Renal interstitial fluid concentrations of angiotensins I and II in anesthetized rats. Hypertension 2002 1.82
18 ATP mediates tubuloglomerular feedback. Am J Physiol Regul Integr Comp Physiol 2002 1.78
19 Angiotensin II type 1 receptor-mediated augmentation of urinary excretion of endogenous angiotensin II in Val5-angiotensin II-infused rats. Hypertension 2010 1.67
20 Intrarenal AT(1) receptor and ACE binding in ANG II-induced hypertensive rats. Am J Physiol Renal Physiol 2002 1.59
21 Heme oxygenase induction attenuates afferent arteriolar autoregulatory responses. Am J Physiol Renal Physiol 2008 1.48
22 Young Scholars Award Lecture: Intratubular angiotensinogen in hypertension and kidney diseases. Am J Hypertens 2006 1.46
23 Intracellular ANG II induces cytosolic Ca2+ mobilization by stimulating intracellular AT1 receptors in proximal tubule cells. Am J Physiol Renal Physiol 2005 1.45
24 Augmented cyclooxygenase-2 effects on renal function during varying states of angiotensin II. Am J Physiol Renal Physiol 2010 1.45
25 Costimulation with angiotensin II and interleukin 6 augments angiotensinogen expression in cultured human renal proximal tubular cells. Am J Physiol Renal Physiol 2008 1.37
26 Determination of plasma and urinary angiotensinogen levels in rodents by newly developed ELISA. Am J Physiol Renal Physiol 2008 1.34
27 Augmentation of endogenous intrarenal angiotensin II levels in Val5-ANG II-infused rats. Am J Physiol Renal Physiol 2009 1.33
28 Intrarenal mouse renin-angiotensin system during ANG II-induced hypertension and ACE inhibition. Am J Physiol Renal Physiol 2009 1.30
29 Increased renin excretion is associated with augmented urinary angiotensin II levels in chronic angiotensin II-infused hypertensive rats. Am J Physiol Renal Physiol 2011 1.27
30 Enhanced superoxide generation modulates renal function in ANG II-induced hypertensive rats. Am J Physiol Renal Physiol 2005 1.27
31 AT1 receptor-mediated accumulation of extracellular angiotensin II in proximal tubule cells: role of cytoskeleton microtubules and tyrosine phosphatases. Am J Physiol Renal Physiol 2006 1.27
32 Angiotensin II stimulates renin in inner medullary collecting duct cells via protein kinase C and independent of epithelial sodium channel and mineralocorticoid receptor activity. Hypertension 2011 1.25
33 Renal interstitial fluid angiotensin I and angiotensin II concentrations during local angiotensin-converting enzyme inhibition. J Am Soc Nephrol 2002 1.24
34 Angiotensin-converting enzyme-derived angiotensin II formation during angiotensin II-induced hypertension. Hypertension 2008 1.20
35 ACE2-mediated reduction of oxidative stress in the central nervous system is associated with improvement of autonomic function. PLoS One 2011 1.16
36 Essential role of AT1A receptor in the development of 2K1C hypertension. Hypertension 2002 1.15
37 Collecting Duct Renin: A major player in Angiotensin II-dependent Hypertension. J Am Soc Hypertens 2010 1.14
38 Involvement of the brain (pro)renin receptor in cardiovascular homeostasis. Circ Res 2010 1.14
39 Angiotensin II type 1 receptor-mediated augmentation of renal interstitial fluid angiotensin II in angiotensin II-induced hypertension. J Hypertens 2003 1.14
40 Intrarenal angiotensin-converting enzyme induces hypertension in response to angiotensin I infusion. J Am Soc Nephrol 2010 1.13
41 Brain-targeted (pro)renin receptor knockdown attenuates angiotensin II-dependent hypertension. Hypertension 2012 1.12
42 Pivotal role of angiotensin II receptor subtype 1A in the development of two-kidney, one-clip hypertension: study in angiotensin II receptor subtype 1A knockout mice. J Hypertens 2008 1.11
43 Aldosterone receptor antagonism exacerbates intrarenal angiotensin II augmentation in ANG II-dependent hypertension. Am J Physiol Renal Physiol 2007 1.11
44 Proximal tubular fluid angiotensin II levels in angiotensin II-induced hypertensive rats. J Hypertens 2003 1.10
45 Renal renin-angiotensin system. Contrib Nephrol 2004 1.09
46 Cardinal role of the intrarenal renin-angiotensin system in the pathogenesis of diabetic nephropathy. J Investig Med 2013 1.09
47 Reciprocal changes in renal ACE/ANG II and ACE2/ANG 1-7 are associated with enhanced collecting duct renin in Goldblatt hypertensive rats. Am J Physiol Renal Physiol 2011 1.08
48 Interferon-γ biphasically regulates angiotensinogen expression via a JAK-STAT pathway and suppressor of cytokine signaling 1 (SOCS1) in renal proximal tubular cells. FASEB J 2012 1.08
49 Tumor necrosis factor-{alpha} suppresses angiotensinogen expression through formation of a p50/p50 homodimer in human renal proximal tubular cells. Am J Physiol Cell Physiol 2010 1.06
50 Natriuretic peptide receptor A mediates renal sodium excretory responses to blood volume expansion. Am J Physiol Renal Physiol 2003 1.05
51 Purinergic receptors contribute to early mesangial cell transformation and renal vessel hypertrophy during angiotensin II-induced hypertension. Am J Physiol Renal Physiol 2007 1.05
52 High-salt intake enhances superoxide activity in eNOS knockout mice leading to the development of salt sensitivity. Am J Physiol Renal Physiol 2010 1.03
53 IL-6 augments angiotensinogen in primary cultured renal proximal tubular cells. Mol Cell Endocrinol 2009 1.03
54 Renal nuclear angiotensin II receptors in normal and hypertensive rats. Acta Physiol Hung 2002 1.01
55 Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors. Hypertension 2012 1.00
56 AT1 receptor-mediated augmentation of angiotensinogen, oxidative stress, and inflammation in ANG II-salt hypertension. Am J Physiol Renal Physiol 2011 0.99
57 Interaction between endogenously produced carbon monoxide and nitric oxide in regulation of renal afferent arterioles. Am J Physiol Heart Circ Physiol 2006 0.99
58 Salt-induced renal injury in SHRs is mediated by AT1 receptor activation. J Hypertens 2011 0.98
59 Calcium and chloride channel activation by angiotensin II-AT1 receptors in preglomerular vascular smooth muscle cells. Am J Physiol Renal Physiol 2005 0.98
60 Activation of the renin-angiotensin system by a low-salt diet does not augment intratubular angiotensinogen and angiotensin II in rats. Am J Physiol Renal Physiol 2013 0.97
61 Acute angiotensin II infusions elicit pressure natriuresis in mice and reduce distal fractional sodium reabsorption. Hypertension 2008 0.97
62 AT1 receptor blockade prevents the increase in blood pressure and the augmentation of intrarenal ANG II levels in hypertensive Cyp1a1-Ren2 transgenic rats fed with a high-salt diet. Am J Med Sci 2010 0.94
63 Evolving concepts on regulation and function of renin in distal nephron. Pflugers Arch 2012 0.94
64 Divergent localization of angiotensinogen mRNA and protein in proximal tubule segments of normal rat kidney. J Hypertens 2012 0.92
65 Afferent arteriolar vasodilator effect of adenosine predominantly involves adenosine A2B receptor activation. Am J Physiol Renal Physiol 2010 0.91
66 T-type calcium channels in the regulation of afferent and efferent arterioles in rats. Am J Physiol Renal Physiol 2003 0.91
67 Nitric oxide synthase inhibition activates L- and T-type Ca2+ channels in afferent and efferent arterioles. Am J Physiol Renal Physiol 2005 0.89
68 ANP-mediated inhibition of distal nephron fractional sodium reabsorption in wild-type and mice overexpressing natriuretic peptide receptor. Am J Physiol Renal Physiol 2009 0.89
69 Glomerular permeability: a never-ending saga. Am J Physiol Renal Physiol 2009 0.87
70 Contribution of a nuclear factor-kappaB binding site to human angiotensinogen promoter activity in renal proximal tubular cells. Hypertension 2011 0.87
71 Bilirubin exerts renoprotective effects in angiotensin II-hypertension. Am J Med Sci 2010 0.87
72 Renal hemodynamic and excretory responses to intra-arterial infusion of peroxynitrite in anesthetized rats. Am J Physiol Renal Physiol 2008 0.85
73 Adenosine A2 receptor activation attenuates afferent arteriolar autoregulation during adenosine receptor saturation in rats. Hypertension 2007 0.85
74 Angiotensin II-mediated constriction of afferent and efferent arterioles involves T-type Ca2+ channel activation. Am J Nephrol 2004 0.84
75 Nebivolol-induced vasodilation of renal afferent arterioles involves β3-adrenergic receptor and nitric oxide synthase activation. Am J Physiol Renal Physiol 2012 0.83
76 The increasing complexity of the intratubular Renin-Angiotensin system. J Am Soc Nephrol 2012 0.83
77 Inhibition of heme oxygenase augments tubular sodium reabsorption. Am J Physiol Renal Physiol 2011 0.83
78 Renal interstitial fluid ATP responses to arterial pressure and tubuloglomerular feedback activation during calcium channel blockade. Am J Physiol Heart Circ Physiol 2005 0.82
79 Human proximal tubular cell responses to angiotensin II analyzed using DNA microarray. Eur J Pharmacol 2003 0.82
80 Contribution of renal purinergic receptors to renal vasoconstriction in angiotensin II-induced hypertensive rats. Am J Physiol Renal Physiol 2011 0.81
81 Angiotensin II-induced reduction in body mass is Ang II receptor mediated in association with elevated corticosterone. Growth Horm IGF Res 2010 0.80
82 Urinary Angiotensinogen as a Novel Biomarker of Intrarenal Renin-Angiotensin System in Chronic Kidney Disease. Int Rev Thromb 2011 0.80
83 The complex interplay between cyclooxygenase-2 and angiotensin II in regulating kidney function. Curr Opin Nephrol Hypertens 2012 0.80
84 Renal heme oxygenase-1 induction with hemin augments renal hemodynamics, renal autoregulation, and excretory function. Int J Hypertens 2012 0.79
85 Aldosterone Receptor Antagonism Reduces Urinary C-Reactive Protein Excretion in Angiotensin II-Infused, Hypertensive Rats. J Am Soc Hypertens 2010 0.79
86 ROCK/NF-κB axis-dependent augmentation of angiotensinogen by angiotensin II in primary-cultured preglomerular vascular smooth muscle cells. Am J Physiol Renal Physiol 2014 0.79
87 Prorenin receptor in distal nephron segments of 2-kidney, 1-clip goldblatt hypertensive rats. Ochsner J 2013 0.79
88 The sodium-activated sodium channel is expressed in the rat kidney thick ascending limb and collecting duct cells and is upregulated during high salt intake. Am J Physiol Renal Physiol 2012 0.79
89 Attenuated renal vascular responses to acute angiotensin II infusion in smooth muscle-specific Na+/Ca2+ exchanger knockout mice. Am J Physiol Renal Physiol 2011 0.77
90 Disruption of Npr1 gene differentially regulates the juxtaglomerular and distal tubular renin levels in null mutant mice. Int J Physiol Pathophysiol Pharmacol 2012 0.77
91 Renoprotective effects of direct renin inhibition in glomerulonephritis. Am J Med Sci 2014 0.76
92 The legacy of Homer W. Smith: mechanistic insights into renal physiology. J Clin Invest 2004 0.75
93 Physiology: hemodynamics, endothelial function, renin-angiotensin-aldosterone system, sympathetic nervous system. J Am Soc Hypertens 2014 0.75
94 Role of atrial natriuretic peptide in mediating the blood pressure-independent natriuresis elicited by systemic inhibition of nitric oxide. Pflugers Arch 2014 0.75
95 In memoriam. Arthur C. Guyton (1919-2003). Physiologist 2003 0.75