Cerebrospinal fluid tau and ptau(181) increase with cortical amyloid deposition in cognitively normal individuals: implications for future clinical trials of Alzheimer's disease.

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Published in EMBO Mol Med on November 01, 2009

Authors

Anne M Fagan1, Mark A Mintun, Aarti R Shah, Patricia Aldea, Catherine M Roe, Robert H Mach, Daniel Marcus, John C Morris, David M Holtzman

Author Affiliations

1: Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA. fagana@neuro.wustl.edu

Associated clinical trials:

Cognitive, Morphological and Neurobiological Progressive Aspects in Bipolar Disorders in the Elderly: Toward to a Neurodegenerescence Detection? (BIPAGE) | NCT02843906

Study of Degenerescence CSF Hallmarks in Older Bipolar Patients (BPL-1318) | NCT02836054

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