Published in Neurobiol Dis on January 04, 2010
Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice. PLoS One (2017) 1.39
Utilization of APPswe/PS1dE9 Transgenic Mice in Research of Alzheimer's Disease: Focus on Gene Therapy and Cell-Based Therapy Applications. Int J Alzheimers Dis (2011) 0.86
BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A (2013) 0.86
IGF2 ameliorates amyloidosis, increases cholinergic marker expression and raises BMP9 and neurotrophin levels in the hippocampus of the APPswePS1dE9 Alzheimer's disease model mice. PLoS One (2014) 0.85
Mitochondrial oxygen consumption deficits in skeletal muscle isolated from an Alzheimer's disease-relevant murine model. BMC Neurosci (2014) 0.84
Chronic cannabidiol treatment improves social and object recognition in double transgenic APPswe/PS1∆E9 mice. Psychopharmacology (Berl) (2014) 0.82
Acetyl-CoA the key factor for survival or death of cholinergic neurons in course of neurodegenerative diseases. Neurochem Res (2013) 0.79
A longitudinal study of cognition, proton MR spectroscopy and synaptic and neuronal pathology in aging wild-type and AβPPswe-PS1dE9 mice. PLoS One (2013) 0.79
Apolipoprotein E4 reduces evoked hippocampal acetylcholine release in adult mice. J Neurochem (2015) 0.76
A comparative evaluation of a novel vaccine in APP/PS1 mouse models of Alzheimer's disease. Biomed Res Int (2015) 0.76
Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer's disease-relevant murine model. BMC Neurol (2015) 0.76
Abnormal Population Responses in the Somatosensory Cortex of Alzheimer's Disease Model Mice. Sci Rep (2016) 0.75
Allosteric Modulation of Muscarinic Acetylcholine Receptors. Pharmaceuticals (Basel) (2010) 0.75
Intrinsic Cholinergic Neurons in the Hippocampus: Fact or Artifact? Front Synaptic Neurosci (2016) 0.75
Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy. J Neurosci (2009) 2.33
Neurocognitive aging: prior memories hinder new hippocampal encoding. Trends Neurosci (2006) 2.20
Age-associated alterations of hippocampal place cells are subregion specific. J Neurosci (2005) 1.82
Increased fMRI responses during encoding in mild cognitive impairment. Neurobiol Aging (2006) 1.74
Role of alpha-synuclein in presynaptic dopamine recruitment. J Neurosci (2004) 1.74
Visual presentation of novel objects and new spatial arrangements of objects differentially activates the medial temporal lobe subareas in humans. Eur J Neurosci (2004) 1.63
Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's disease. J Neurochem (2013) 1.51
Gender differences in the amount and deposition of amyloidbeta in APPswe and PS1 double transgenic mice. Neurobiol Dis (2003) 1.48
Orexin loss in Huntington's disease. Hum Mol Genet (2004) 1.33
Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A (2009) 1.31
Flexible polyimide microelectrode array for in vivo recordings and current source density analysis. Biosens Bioelectron (2006) 1.28
Pyrrolidine dithiocarbamate activates Akt and improves spatial learning in APP/PS1 mice without affecting beta-amyloid burden. J Neurosci (2007) 1.28
Human intravenous immunoglobulin provides protection against Aβ toxicity by multiple mechanisms in a mouse model of Alzheimer's disease. J Neuroinflammation (2010) 1.18
Memantine improves spatial learning in a transgenic mouse model of Alzheimer's disease. J Pharmacol Exp Ther (2004) 1.17
Longitudinal observation on CSF Abeta42 levels in young to middle-aged amyloid precursor protein/presenilin-1 doubly transgenic mice. Neurobiol Dis (2004) 1.17
Cognitive aging and the hippocampus: how old rats represent new environments. J Neurosci (2004) 1.17
Non-fibrillar beta-amyloid abates spike-timing-dependent synaptic potentiation at excitatory synapses in layer 2/3 of the neocortex by targeting postsynaptic AMPA receptors. Eur J Neurosci (2006) 1.15
Expression of interleukin-18 is increased in the brains of Alzheimer's disease patients. Neurobiol Aging (2007) 1.15
Locomotor activity and evoked dopamine release are reduced in mice overexpressing A30P-mutated human alpha-synuclein. Neurobiol Dis (2005) 1.15
Cortical glutamate-dopamine interaction and ketamine-induced psychotic symptoms in man. Psychopharmacology (Berl) (2005) 1.14
Nuclear factor erythroid 2-related factor 2 protects against beta amyloid. Mol Cell Neurosci (2008) 1.11
Encoding of novel picture pairs activates the perirhinal cortex: an fMRI study. Hippocampus (2003) 1.10
Molecular reorganization of endocannabinoid signalling in Alzheimer's disease. Brain (2011) 1.10
Hypothermia in mice tested in Morris water maze. Behav Brain Res (2003) 1.09
Differences in kinetics of xanomeline binding and selectivity of activation of G proteins at M(1) and M(2) muscarinic acetylcholine receptors. Mol Pharmacol (2006) 1.09
Memantine lowers amyloid-beta peptide levels in neuronal cultures and in APP/PS1 transgenic mice. J Neurosci Res (2010) 1.08
WNT signaling in activated microglia is proinflammatory. Glia (2010) 1.07
Cognition-enhancing and anxiolytic effects of memantine. Neuropharmacology (2008) 1.06
Tau hyperphosphorylation correlates with reduced methylation of protein phosphatase 2A. Neurobiol Dis (2008) 1.03
Role of alpha-synuclein in synaptic glutamate release. Neurobiol Dis (2007) 1.02
Individual differences in neurocognitive aging of the medial temporal lobe. Age (Dordr) (2006) 1.01
Impaired TrkB receptor signaling contributes to memory impairment in APP/PS1 mice. Neurobiol Aging (2011) 1.01
Effects of human intravenous immunoglobulin on amyloid pathology and neuroinflammation in a mouse model of Alzheimer's disease. J Neuroinflammation (2012) 0.99
Effects of ovariectomy and estrogen treatment on learning and hippocampal neurotransmitters in mice. Horm Behav (2002) 0.97
Hippocampal A beta 42 levels correlate with spatial memory deficit in APP and PS1 double transgenic mice. Neurobiol Dis (2002) 0.97
Multiple cellular and molecular mechanisms are involved in human Aβ clearance by transplanted adult astrocytes. Glia (2011) 0.96
Spontaneous epileptiform discharges in a mouse model of Alzheimer's disease are suppressed by antiepileptic drugs that block sodium channels. Epilepsy Res (2011) 0.95
Cholinergic system regulation of spatial representation by the hippocampus. Hippocampus (2002) 0.95
Decreased reuptake of dopamine in the dorsal striatum in the absence of α-synuclein. Brain Res (2011) 0.95
The transcriptional repressor REST is a critical regulator of the neurosecretory phenotype. J Neurochem (2006) 0.94
Discriminating accuracy of medial temporal lobe volumetry and fMRI in mild cognitive impairment. Hippocampus (2009) 0.94
Estrogen treatment alleviates NMDA-antagonist induced hippocampal LTP blockade and cognitive deficits in ovariectomized mice. Neurobiol Learn Mem (2003) 0.92
Effects of long-term ovariectomy and estrogen treatment on maze learning in aged mice. Exp Gerontol (2004) 0.92
Mobile phone radiation and the developing brain: behavioral and morphological effects in juvenile rats. Radiat Res (2007) 0.92
Lack of collagen XV impairs peripheral nerve maturation and, when combined with laminin-411 deficiency, leads to basement membrane abnormalities and sensorimotor dysfunction. J Neurosci (2010) 0.91
Neurochemical mapping of the human hippocampus reveals perisynaptic matrix around functional synapses in Alzheimer's disease. Acta Neuropathol (2012) 0.90
Amyloid beta deposition is related to decreased glucose transporter-1 levels and hippocampal atrophy in brains of aged APP/PS1 mice. Brain Res (2007) 0.90
Noradrenaline overflow in mouse dentate gyrus following locus coeruleus and natural stimulation: real-time monitoring by in vivo voltammetry. J Neurochem (2005) 0.89
Abnormal compartmentalization of norepinephrine in mouse dentate gyrus in alpha-synuclein knockout and A30P transgenic mice. J Neurochem (2006) 0.88
Increased expression of Abeta degrading enzyme IDE in the cortex of transgenic mice with Alzheimer's disease-like neuropathology. Neurosci Lett (2008) 0.88
Distinct and overlapping fMRI activation networks for processing of novel identities and locations of objects. Eur J Neurosci (2005) 0.87
Detection of choline transporter-like 1 protein CTL1 in neuroblastoma x glioma cells and in the CNS, and its role in choline uptake. J Neurochem (2009) 0.87
Neurotrophins and dementia--keeping in touch. Neuron (2006) 0.87
From brain to food: analysis of phosphatidylcholins, lyso-phosphatidylcholins and phosphatidylcholin-plasmalogens derivates in Alzheimer's disease human post mortem brains and mice model via mass spectrometry. J Chromatogr A (2011) 0.87
Fabrication and testing of polyimide-based microelectrode arrays for cortical mapping of evoked potentials. Biosens Bioelectron (2009) 0.87
Aging and alpha-synuclein affect synaptic plasticity in the dentate gyrus. J Neural Transm (Vienna) (2008) 0.86
Spermidine/spermine N1-acetyltransferase overexpression in mice induces hypoactivity and spatial learning impairment. Pharmacol Biochem Behav (2004) 0.86
Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice. J Cell Mol Med (2012) 0.86
Effects of NMDA-receptor antagonist treatment on c-fos expression in rat brain areas implicated in schizophrenia. Cell Mol Neurobiol (2004) 0.85
Methylphenidate modifies overflow and presynaptic compartmentalization of dopamine via an α-synuclein-dependent mechanism. J Pharmacol Exp Ther (2012) 0.85
Uncoupling of M1 muscarinic receptor/G-protein interaction by amyloid β(1-42). Neuropharmacology (2012) 0.85
Brain reward in the absence of alpha-synuclein. Neuroreport (2006) 0.85
Alteration of cortical EEG in mice carrying mutated human APP transgene. Brain Res (2002) 0.85
Place cells of aged rats in two visually identical compartments. Neurobiol Aging (2004) 0.84
The impact of Bdnf gene deficiency to the memory impairment and brain pathology of APPswe/PS1dE9 mouse model of Alzheimer's disease. PLoS One (2013) 0.84
In vivo regulation of dopamine and noradrenaline release by alpha2A-adrenoceptors in the mouse nucleus accumbens. J Neurochem (2004) 0.83
A novel delayed non-match to sample object recognition task that allows simultaneous in vivo microdialysis. J Neurosci Methods (2010) 0.83
Behavioural and neurochemical response of alpha-synuclein A30P transgenic mice to the effects of L-DOPA. Neuropharmacology (2008) 0.83
Anthocyanin-enriched bilberry and blackcurrant extracts modulate amyloid precursor protein processing and alleviate behavioral abnormalities in the APP/PS1 mouse model of Alzheimer's disease. J Nutr Biochem (2012) 0.83
In vivo regulation of dopamine and noradrenaline release by alpha2A-adrenoceptors in the mouse prefrontal cortex. Eur J Neurosci (2002) 0.82
Effects of fimbria-fornix lesion and amyloid pathology on spatial learning and memory in transgenic APP+PS1 mice. Behav Brain Res (2002) 0.82
Clusters of secretagogin-expressing neurons in the aged human olfactory tract lack terminal differentiation. Proc Natl Acad Sci U S A (2012) 0.81
More than one way to toy with ChAT and VAChT. J Physiol Paris (2001) 0.81
Plant sterols the better cholesterol in Alzheimer's disease? A mechanistical study. J Neurosci (2013) 0.81
Membrane cholesterol content influences binding properties of muscarinic M2 receptors and differentially impacts activation of second messenger pathways. Eur J Pharmacol (2009) 0.81
Increased cortical and thalamic excitability in freely moving APPswe/PS1dE9 mice modeling epileptic activity associated with Alzheimer's disease. Cereb Cortex (2012) 0.81
Artificial theta stimulation impairs encoding of contextual fear memory. PLoS One (2012) 0.81
Long-term agonist stimulation of IP prostanoid receptor depletes the cognate G(s)alpha protein in membrane domains but does not change the receptor level. Biochim Biophys Acta (2004) 0.80
Genetic ablation of tenascin-C expression leads to abnormal hippocampal CA1 structure and electrical activity in vivo. Hippocampus (2009) 0.80
Abeta levels in serum, CSF and brain, and cognitive deficits in APP + PS1 transgenic mice. Neuroreport (2003) 0.80
Fimbria-fornix lesion does not affect APP levels and amyloid deposition in the hippocampus of APP+PS1 double transgenic mice. Exp Neurol (2002) 0.80
Alpha 2C-adrenoceptor mediated regulation of cortical EEG arousal. Neuropharmacology (2002) 0.79
Effects of memantine and donepezil on cortical and hippocampal acetylcholine levels and object recognition memory in rats. Neuropharmacology (2011) 0.79
Parallel increase in p70 kinase activation and tau phosphorylation (S262) with Abeta overproduction. FEBS Lett (2007) 0.79
Amyloid precursor protein α- and β-cleaved ectodomains exert opposing control of cholesterol homeostasis via SREBP2. FASEB J (2013) 0.79
Pharmacological characterisation of a structurally novel α2C-adrenoceptor antagonist ORM-10921 and its effects in neuropsychiatric models. Basic Clin Pharmacol Toxicol (2013) 0.78
Chronic treatment with amyloid beta(1-42) inhibits non-cholinergic high-affinity choline transport in NG108-15 cells through protein kinase C signaling. Brain Res (2005) 0.77
Increased hippocampal and cortical beta oscillations in mice deficient for the HNK-1 sulfotransferase. Mol Cell Neurosci (2006) 0.77
Mechanics of self-stimulation and dopamine release in the nucleus accumbens. Neuroreport (2007) 0.77
Divergence of allosteric effects of rapacuronium on binding and function of muscarinic receptors. BMC Pharmacol (2009) 0.77
Lipid-Based Diets Improve Muscarinic Neurotransmission in the Hippocampus of Transgenic APPswe/PS1dE9 Mice. Curr Alzheimer Res (2015) 0.77
Elevated levels of Abeta1-40 and Abeta1-42 do not alter the binding sites of nicotinic receptor subtypes in the brain of APPswe and PS1 double transgenic mice. Neurosci Lett (2002) 0.77
The increase of choline acetyltransferase activity by docosahexaenoic acid in NG108-15 cells grown in serum-free medium is independent of its effect on cell growth. Neurochem Res (2006) 0.76
PS dependent APP cleavage regulates glucosylceramide synthase and is affected in Alzheimer's disease. Cell Physiol Biochem (2014) 0.76
Normal Amplitude of Electroretinography and Visual Evoked Potential Responses in AβPP/PS1 Mice. J Alzheimers Dis (2016) 0.75
Is it possible to improve memory with drugs in health people? Duodecim (1) 0.75