Published in Adv Exp Med Biol on January 01, 2009
Proteomic analysis of secretory products from the model gastrointestinal nematode Heligmosomoides polygyrus reveals dominance of venom allergen-like (VAL) proteins. J Proteomics (2011) 1.16
Impact of Schistosoma japonicum infection on collagen-induced arthritis in DBA/1 mice: a murine model of human rheumatoid arthritis. PLoS One (2011) 0.96
Helminth infections decrease host susceptibility to immune-mediated diseases. J Immunol (2014) 0.93
Crude extracts of Caenorhabditis elegans suppress airway inflammation in a murine model of allergic asthma. PLoS One (2012) 0.84
Schistosoma japonicum HSP60-derived peptide SJMHE1 suppresses delayed-type hypersensitivity in a murine model. Parasit Vectors (2016) 0.76
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature (2010) 10.34
Transcription factor RORα is critical for nuocyte development. Nat Immunol (2012) 3.72
A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming. Nat Genet (2009) 2.96
The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis. Gastroenterology (2007) 2.87
Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model. J Allergy Clin Immunol (2010) 2.15
A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis. J Exp Med (2013) 2.11
IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration. Sci Transl Med (2014) 2.11
The alarmin interleukin-33 drives protective antiviral CD8⁺ T cell responses. Science (2012) 2.10
Infection with a helminth parasite prevents experimental colitis via a macrophage-mediated mechanism. J Immunol (2007) 2.09
Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice. Gut (2012) 1.97
Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages. J Immunol (2004) 1.91
SIGN-R1 contributes to protection against lethal pneumococcal infection in mice. J Exp Med (2004) 1.73
A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis. J Exp Med (2013) 1.69
Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function. Gastroenterology (2010) 1.64
Helminth infection protects mice from anaphylaxis via IL-10-producing B cells. J Immunol (2004) 1.57
Association between tuberculosis and a polymorphic NFkappaB binding site in the interferon gamma gene. Lancet (2003) 1.51
T1/ST2 expression on Th2 cells negatively regulates allergic pulmonary inflammation. Eur J Immunol (2007) 1.50
Blockade of B7-H1 (programmed death ligand 1) enhances humoral immunity by positively regulating the generation of T follicular helper cells. J Immunol (2011) 1.47
Flotillin microdomains interact with the cortical cytoskeleton to control uropod formation and neutrophil recruitment. J Cell Biol (2010) 1.40
A role for TLR4 in Clostridium difficile infection and the recognition of surface layer proteins. PLoS Pathog (2011) 1.39
Cutting edge: IL-25 elicits innate lymphoid type 2 and type II NKT cells that regulate obesity in mice. J Immunol (2013) 1.38
The schistosoma granuloma: friend or foe? Front Immunol (2013) 1.34
Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects. J Allergy Clin Immunol (2013) 1.30
Lethal, neonatal ichthyosis with increased proteolytic processing of filaggrin in a mouse model of Netherton syndrome. Hum Mol Genet (2004) 1.30
Tim-1 is induced on germinal centre B cells through B-cell receptor signalling but is not essential for the germinal centre response. Immunology (2010) 1.24
Helminth-modified pulmonary immune response protects mice from allergen-induced airway hyperresponsiveness. J Immunol (2006) 1.21
Mast cells as sensors of cell injury through IL-33 recognition. J Immunol (2011) 1.21
An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia. J Immunol (2010) 1.20
The Toll-like receptor 3 L412F polymorphism and disease progression in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2013) 1.17
Th2 activities induced during virgin T cell priming in the absence of IL-4, IL-13, and B cells. J Immunol (2002) 1.16
IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis. Proc Natl Acad Sci U S A (2013) 1.16
Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activity. J Exp Med (2005) 1.13
Upregulation of retinal dehydrogenase 2 in alternatively activated macrophages during retinoid-dependent type-2 immunity to helminth infection in mice. PLoS Pathog (2012) 1.13
Effect of filaggrin breakdown products on growth of and protein expression by Staphylococcus aureus. J Allergy Clin Immunol (2010) 1.12
Characterization of signaling pathways activated by the interleukin 1 (IL-1) receptor homologue T1/ST2. A role for Jun N-terminal kinase in IL-4 induction. J Biol Chem (2002) 1.12
Retracted Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization. Immunity (2012) 1.12
IL-33 shifts the balance from osteoclast to alternatively activated macrophage differentiation and protects from TNF-alpha-mediated bone loss. J Immunol (2011) 1.12
Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways. Proc Natl Acad Sci U S A (2013) 1.12
Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency. J Allergy Clin Immunol (2012) 1.07
Inhibition of type 1 cytokine-mediated inflammation by a soluble CD30 homologue encoded by ectromelia (mousepox) virus. J Exp Med (2002) 1.05
T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles. Arthritis Res Ther (2012) 1.03
SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses. J Exp Med (2011) 1.01
Intraperitoneal influx of neutrophils in response to IL-33 is mast cell-dependent. Blood (2012) 0.96
C-type lectin SIGN-R1 has a role in experimental colitis and responsiveness to lipopolysaccharide. J Immunol (2010) 0.95
Enhancement of chemokine function as an immunomodulatory strategy employed by human herpesviruses. PLoS Pathog (2012) 0.94
Soluble IL-2Rα (sCD25) exacerbates autoimmunity and enhances the development of Th17 responses in mice. PLoS One (2012) 0.94
Helminth therapies: translating the unknown unknowns to known knowns. Int J Parasitol (2013) 0.94
The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic shock via alternative activation of macrophages and IL-10 production by B1 cells. Shock (2011) 0.93
Participation of MyD88 and interleukin-33 as innate drivers of Th2 immunity to Trichinella spiralis. Infect Immun (2013) 0.93
Reduced expression of epidermal growth factor receptor, E-cadherin, and occludin in the skin of flaky tail mice is due to filaggrin and loricrin deficiencies. Am J Pathol (2012) 0.93
Aging impairs peritoneal but not bone marrow-derived macrophage phagocytosis. Aging Cell (2014) 0.92
Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis. Nat Immunol (2013) 0.92
Identification of the synthetic cannabinoid R(+)WIN55,212-2 as a novel regulator of IFN regulatory factor 3 activation and IFN-beta expression: relevance to therapeutic effects in models of multiple sclerosis. J Biol Chem (2011) 0.92
Leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction induces a novel genetic signature resulting in T-cells refractory to transforming growth factor-β signaling. J Biol Chem (2012) 0.91
Partial redundancy of the pattern recognition receptors, scavenger receptors, and C-type lectins for the long-term control of Mycobacterium tuberculosis infection. J Immunol (2010) 0.90
Innate type 2 cells and asthma. Curr Opin Pharmacol (2012) 0.89
The C-type lectin SIGNR1 binds Schistosoma mansoni antigens in vitro, but SIGNR1-deficient mice have normal responses during schistosome infection. Infect Immun (2008) 0.88
Lipid rafts are disrupted in mildly inflamed intestinal microenvironments without overt disruption of the epithelial barrier. Am J Physiol Gastrointest Liver Physiol (2012) 0.88
Decoy receptors in the regulation of T helper cell type 2 responses. J Exp Med (2003) 0.87
Identification of a functioning mitochondrial uncoupling protein 1 in thymus. J Biol Chem (2005) 0.86
Orphan receptor IL-17RD tunes IL-17A signalling and is required for neutrophilia. Nat Commun (2012) 0.86
T helper type-2 cytokine responses: potential therapeutic targets. Curr Opin Pharmacol (2003) 0.86
Hypoxia-dependent regulation of inflammatory pathways in immune cells. J Clin Invest (2016) 0.86
Regulation of Foxp3+ inducible regulatory T cell stability by SOCS2. J Immunol (2013) 0.85
Previous infection with the nematode Nippostrongylus brasiliensis alters the immune specific response against Chlamydophila abortus infection. Microb Pathog (2002) 0.85
Effects of Lactobacillus salivarius 433118 on intestinal inflammation, immunity status and in vitro colon function in two mouse models of inflammatory bowel disease. Dig Dis Sci (2007) 0.85
Specific intracellular adhesion molecule-grabbing nonintegrin R1 is not involved in the murine antibody response to pneumococcal polysaccharides. Infect Immun (2007) 0.84
Activation of human invariant natural killer T cells with a thioglycoside analogue of α-galactosylceramide. Clin Immunol (2011) 0.84
Ursodeoxycholic acid attenuates colonic epithelial secretory function. J Physiol (2013) 0.83
Cutting edge: suppression of GM-CSF expression in murine and human T cells by IL-27. J Immunol (2012) 0.83
Lymphomagenesis, hydronephrosis, and autoantibodies result from dysregulation of IL-9 and are differentially dependent on Th2 cytokines. J Immunol (2004) 0.83
Generation of parasite antigens for use in Toll-like receptor research. Methods Mol Biol (2009) 0.83
Farnesoid X receptor agonists attenuate colonic epithelial secretory function and prevent experimental diarrhoea in vivo. Gut (2013) 0.82
Protamine sulfate down-regulates thrombin generation by inhibiting factor V activation. Blood (2009) 0.82
Mitochondrial uncoupling protein 1 expression in thymocytes. Biochim Biophys Acta (2008) 0.81
MyD88 adaptor-like (Mal) regulates intestinal homeostasis and colitis-associated colorectal cancer in mice. Am J Physiol Gastrointest Liver Physiol (2014) 0.80
Hydroxylase inhibition attenuates colonic epithelial secretory function and ameliorates experimental diarrhea. FASEB J (2010) 0.79
Toll IL-1R8/single Ig IL-1-related receptor regulates psoriasiform inflammation through direct inhibition of innate IL-17A expression by γδ T cells. J Immunol (2013) 0.79
The synthetic cannabinoid R(+)WIN55,212-2 augments interferon-β expression via peroxisome proliferator-activated receptor-α. J Biol Chem (2012) 0.78
Impaired basophil induction leads to an age-dependent innate defect in type 2 immunity during helminth infection in mice. J Immunol (2011) 0.78
Activated factor X signaling via protease-activated receptor 2 suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells. Haematologica (2013) 0.78
Why does work on same mouse models give different results? Nature (2008) 0.77
The generation of regulatory B cells by helminth parasites. Methods Mol Biol (2014) 0.76
A mineral extract from red algae ameliorates chronic spontaneous colitis in IL-10 deficient mice in a mouse strain dependent manner. Phytother Res (2013) 0.75