John M Greally

Author PubWeight™ 123.19‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell 2010 8.79
2 Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences. Nature 2007 7.91
3 DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia. Cancer Cell 2010 6.72
4 Comparative isoschizomer profiling of cytosine methylation: the HELP assay. Genome Res 2006 5.99
5 MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation. Blood 2009 4.00
6 LINE-1 activity in facultative heterochromatin formation during X chromosome inactivation. Cell 2010 3.70
7 Epigenomics: beyond CpG islands. Nat Rev Genet 2004 3.21
8 CG dinucleotide clustering is a species-specific property of the genome. Nucleic Acids Res 2007 2.48
9 Recommendations for the design and analysis of epigenome-wide association studies. Nat Methods 2013 2.19
10 Cytosine methylation dysregulation in neonates following intrauterine growth restriction. PLoS One 2010 2.10
11 Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomas. Proc Natl Acad Sci U S A 2007 2.06
12 Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations. Blood 2012 1.98
13 Tissue-specific dysregulation of DNA methylation in aging. Aging Cell 2010 1.90
14 High-resolution genome-wide cytosine methylation profiling with simultaneous copy number analysis and optimization for limited cell numbers. Nucleic Acids Res 2009 1.80
15 DNA methylation signatures define molecular subtypes of diffuse large B-cell lymphoma. Blood 2010 1.77
16 An integrative genomic and epigenomic approach for the study of transcriptional regulation. PLoS One 2008 1.76
17 Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features. Blood 2009 1.75
18 Genome-wide determination of DNA methylation by Hpa II tiny fragment enrichment by ligation-mediated PCR (HELP) for the study of acute leukemias. Methods Mol Biol 2009 1.71
19 Epigenetics: perceptive enzymes. Nature 2007 1.71
20 Epigenomic modifications predict active promoters and gene structure in Toxoplasma gondii. PLoS Pathog 2007 1.69
21 A stain upon the silence: genes escaping X inactivation. Trends Genet 2003 1.65
22 An analytical pipeline for genomic representations used for cytosine methylation studies. Bioinformatics 2008 1.64
23 The potential role of epigenomic dysregulation in complex human disease. Trends Genet 2007 1.63
24 Genome-wide and locus-specific DNA hypomethylation in G9a deficient mouse embryonic stem cells. Genes Cells 2007 1.52
25 Cytosine methylation changes in enhancer regions of core pro-fibrotic genes characterize kidney fibrosis development. Genome Biol 2013 1.52
26 Repressor element-1 silencing transcription factor (REST)-dependent epigenetic remodeling is critical to ischemia-induced neuronal death. Proc Natl Acad Sci U S A 2012 1.48
27 Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes. Genome Biol 2013 1.47
28 Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis. PLoS Genet 2011 1.47
29 A pipeline for the quantitative analysis of CG dinucleotide methylation using mass spectrometry. Bioinformatics 2009 1.42
30 Mammalian linker-histone subtypes differentially affect gene expression in vivo. Proc Natl Acad Sci U S A 2003 1.37
31 Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines. Cancer Res 2008 1.36
32 Experimental intrauterine growth restriction induces alterations in DNA methylation and gene expression in pancreatic islets of rats. J Biol Chem 2010 1.36
33 Genomics: Encyclopaedia of humble DNA. Nature 2007 1.35
34 Cell type-specific methylation profiles occurring disproportionately in CpG-less regions that delineate developmental similarity. Genes Cells 2007 1.29
35 Comparative sequence and x-inactivation analyses of a domain of escape in human xp11.2 and the conserved segment in mouse. Genome Res 2004 1.29
36 Optimized design and data analysis of tag-based cytosine methylation assays. Genome Biol 2010 1.23
37 Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol 2013 1.07
38 Reduced-representation methylation mapping. Genome Biol 2008 1.07
39 Genomic organization of the genes Gtf2ird1, Gtf2i, and Ncf1 at the mouse chromosome 5 region syntenic to the human chromosome 7q11.23 Williams syndrome critical region. Genomics 2002 1.05
40 Identification of a candidate regulatory region in the human CD8 gene complex by colocalization of DNase I hypersensitive sites and matrix attachment regions which bind SATB1 and GATA-3. J Immunol 2002 1.05
41 Toxoplasma gondii and Cryptosporidium parvum lack detectable DNA cytosine methylation. Eukaryot Cell 2008 1.03
42 DNA methylation alterations in multiple myeloma as a model for epigenetic changes in cancer. Wiley Interdiscip Rev Syst Biol Med 2010 1.03
43 Introduction to epigenomics and epigenome-wide analysis. Methods Mol Biol 2010 1.02
44 A new class of tissue-specifically methylated regions involving entire CpG islands in the mouse. Genes Cells 2007 1.02
45 Epigenetic abnormalities associated with a chromosome 18(q21-q22) inversion and a Gilles de la Tourette syndrome phenotype. Proc Natl Acad Sci U S A 2003 1.01
46 The Wasp System: an open source environment for managing and analyzing genomic data. Genomics 2012 1.01
47 Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer. Nucleic Acids Res 2013 1.00
48 Late-replicating heterochromatin is characterized by decreased cytosine methylation in the human genome. Genome Res 2011 0.99
49 Aberrant epigenetic and genetic marks are seen in myelodysplastic leukocytes and reveal Dock4 as a candidate pathogenic gene on chromosome 7q. J Biol Chem 2011 0.97
50 DNA methylation profiling using HpaII tiny fragment enrichment by ligation-mediated PCR (HELP). Methods 2010 0.94
51 CG dinucleotide periodicities recognized by the Dnmt3a-Dnmt3L complex are distinctive at retroelements and imprinted domains. Mamm Genome 2009 0.93
52 Unusual characteristics of the DNA binding domain of epigenetic regulatory protein MeCP2 determine its binding specificity. Biochemistry 2014 0.93
53 The HELP assay. Methods Mol Biol 2009 0.92
54 Methylome profiling reveals distinct alterations in phenotypic and mutational subgroups of myeloproliferative neoplasms. Cancer Res 2012 0.92
55 Differential epigenome-wide DNA methylation patterns in childhood obesity-associated asthma. Sci Rep 2013 0.91
56 Lack of evidence for green tea polyphenols as DNA methylation inhibitors in murine prostate. Cancer Prev Res (Phila) 2009 0.90
57 Homez, a homeobox leucine zipper gene specific to the vertebrate lineage. Proc Natl Acad Sci U S A 2003 0.90
58 Epigenetic changes in B lymphocytes associated with house dust mite allergic asthma. Epigenetics 2011 0.89
59 Epigenetic silencing of the circadian clock gene CRY1 is associated with an indolent clinical course in chronic lymphocytic leukemia. PLoS One 2012 0.88
60 HSC commitment-associated epigenetic signature is prognostic in acute myeloid leukemia. J Clin Invest 2014 0.88
61 A blueprint for an international cancer epigenome consortium. A report from the AACR Cancer Epigenome Task Force. Cancer Res 2012 0.87
62 Opposing roles of Dnmt1 in early- and late-stage murine prostate cancer. Mol Cell Biol 2010 0.87
63 Phase II trial of the histone deacetylase inhibitor romidepsin in patients with recurrent/metastatic head and neck cancer. Oral Oncol 2012 0.85
64 Genetic mapping of putative Chrna7 and Luzp2 neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes. BMC Genomics 2005 0.85
65 Astrogenomics: big data, old problems, old solutions? Genome Biol 2013 0.83
66 Large, male germ cell-specific hypomethylated DNA domains with unique genomic and epigenomic features on the mouse X chromosome. DNA Res 2013 0.83
67 Automated computational analysis of genome-wide DNA methylation profiling data from HELP-tagging assays. Methods Mol Biol 2012 0.82
68 How might epigenetic dysregulation in early embryonic life contribute to autism spectrum disorder? Epigenomics 2015 0.81
69 MEN1 tumor-suppressor protein localizes to telomeres during meiosis. Genes Chromosomes Cancer 2002 0.80
70 DNA methylation changes in murine breast adenocarcinomas allow the identification of candidate genes for human breast carcinogenesis. Mamm Genome 2011 0.80
71 The Einstein Genome Gateway using WASP - a high throughput multi-layered life sciences portal for XSEDE. Stud Health Technol Inform 2012 0.80
72 Predictive properties of DNA methylation patterns in primary tumor samples for osteosarcoma relapse status. Epigenetics 2015 0.79
73 Experimental approaches to the study of epigenomic dysregulation in ageing. Exp Gerontol 2010 0.77
74 Convergent and divergent evolution of genomic imprinting in the marsupial Monodelphis domestica. BMC Genomics 2012 0.77
75 Maternal gametic transmission of translocations or inversions of human chromosome 11p15.5 results in regional DNA hypermethylation and downregulation of CDKN1C expression. Genomics 2011 0.77
76 Genome-wide DNA methylation analysis using massively parallel sequencing technologies. Semin Hematol 2013 0.77
77 Allele-specific transcriptional elongation regulates monoallelic expression of the IGF2BP1 gene. Epigenetics Chromatin 2011 0.76
78 LINE-1 Activity in Facultative Heterochromatin Formation during X Chromosome Inactivation. Cell 2016 0.75
79 The Einstein Center for Epigenomics: studying the role of epigenomic dysregulation in human disease. Epigenomics 2009 0.75