Published in Proc Natl Acad Sci U S A on March 15, 1991
Double bands in DNA gel electrophoresis caused by bis-intercalating dyes. Nucleic Acids Res (1995) 1.20
Oligonucleotides form a duplex with non-helical properties on a positively charged surface. Nucleic Acids Res (2001) 0.90
The impact of DNA intercalators on DNA and DNA-processing enzymes elucidated through force-dependent binding kinetics. Nat Commun (2015) 0.87
Stability of the I-motif structure is related to the interactions between phosphodiester backbones. Biophys J (2003) 0.87
Structure-based DNA-targeting strategies with small molecule ligands for drug discovery. Med Res Rev (2013) 0.84
Structural perturbations in DNA caused by bis-intercalation of ditercalinium visualised by atomic force microscopy. Nucleic Acids Res (2002) 0.81
X-ray crystallographic study of DNA duplex cross-linking: simultaneous binding to two d(CGTACG)2 molecules by a bis(9-aminoacridine-4-carboxamide) derivative. Nucleic Acids Res (2006) 0.79
Recent Advances in Developing Small Molecules Targeting Nucleic Acid. Int J Mol Sci (2016) 0.75
DNA Recognition by a Novel Bis-Intercalator, Potent Anticancer Drug XR5944. Curr Top Med Chem (2015) 0.75
DNA repair enzymes. Annu Rev Biochem (1988) 5.16
A bifurcated hydrogen-bonded conformation in the d(A.T) base pairs of the DNA dodecamer d(CGCAAATTTGCG) and its complex with distamycin. Proc Natl Acad Sci U S A (1987) 5.14
Structural analysis of spermine and magnesium ion binding to yeast phenylalanine transfer RNA. Proc Natl Acad Sci U S A (1978) 4.52
Structural comparison of anticancer drug-DNA complexes: adriamycin and daunomycin. Biochemistry (1990) 2.26
Base only binding of spermine in the deep groove of the A-DNA octamer d(GTGTACAC). Biochemistry (1989) 1.51
DNA intercalating compounds as potential antitumor agents. 2. Preparation and properties of 7H-pyridocarbazole dimers. J Med Chem (1980) 1.34
The dependence of the surface electrostatic potential of B-DNA on environmental factors. J Biomol Struct Dyn (1985) 1.12
Geometry of the antitumor drug ditercalinium bisintercalated into d(CpGpCpG)2 by 1H NMR. Proc Natl Acad Sci U S A (1987) 1.03
Structure of nogalamycin bound to a DNA hexamer. Proc Natl Acad Sci U S A (1990) 1.02
Ternary interactions of spermine with DNA: 4'-epiadriamycin and other DNA: anthracycline complexes. Nucleic Acids Res (1990) 1.01
Induction of an abortive and futile DNA repair process in E. coli by the antitumor DNA bifunctional intercalator, ditercalinium: role in polA in death induction. Nucleic Acids Res (1988) 0.96
The noncovalent complex between DNA and the bifunctional intercalator ditercalinium is a substrate for the UvrABC endonuclease of Escherichia coli. Proc Natl Acad Sci U S A (1989) 0.92
Recognition by the DNA repair system of DNA structural alterations induced by reversible drug-DNA interactions. Anticancer Drug Des (1990) 0.88
Structure of 11-deoxydaunomycin bound to DNA containing a phosphorothioate. J Mol Biol (1990) 0.88
1H and 31P nuclear magnetic resonance studies of the differences in DNA deformation induced by anti-tumoral 7H-pyrido[4,3-c]carbazole dimers. J Mol Biol (1989) 0.83
Intercalative binding of ditercalinium to d(CpGpCpG)2: a theoretical study. J Biomol Struct Dyn (1989) 0.82
DNA bis-intercalators as new anti-tumour agents: modulation of the anti-tumour activity by the linking chain rigidity in the ditercalinium series. Anticancer Drug Des (1987) 0.82
Bisintercalation of ditercalinium into a d[CpGpCpG]2 minihelix: structure and dynamics aspects--a 400-MHz 1H-NMR study. Biopolymers (1987) 0.82
Modulation of the antitumor activity by methyl substitutions in the series of 7H-pyridocarbazole monomers and dimers. J Med Chem (1987) 0.81
Study of the bisintercalation of the antitumor drug ditercalinium by 31P-NMR. Biopolymers (1988) 0.79
1H NMR study of the structure of a pyridocarbazole dimer-d[CpGpCpG] complex. Biochimie (1986) 0.79
Relationship between the size and position of substituents on 7H-pyrido[4,3-c]carbazole monomers and dimers and their DNA binding and anti-tumor properties. Anticancer Drug Des (1988) 0.79
Molecular structure of a left-handed double helical DNA fragment at atomic resolution. Nature (1979) 18.01
Sequence-specific recognition of double helical nucleic acids by proteins. Proc Natl Acad Sci U S A (1976) 13.30
Three-dimensional tertiary structure of yeast phenylalanine transfer RNA. Science (1974) 11.02
Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. Proc Natl Acad Sci U S A (1984) 8.84
The chemistry and biology of left-handed Z-DNA. Annu Rev Biochem (1984) 8.57
Transfer RNA: molecular structure, sequence, and properties. Annu Rev Biochem (1976) 7.41
Left-handed double helical DNA: variations in the backbone conformation. Science (1981) 6.64
Structural domains of transfer RNA molecules. Science (1976) 6.07
Electron Microscope Studies of Ribosomal Clusters Synthesizing Hemoglobin. Science (1962) 5.74
The sequence (dC-dA)n X (dG-dT)n forms left-handed Z-DNA in negatively supercoiled plasmids. Proc Natl Acad Sci U S A (1983) 5.69
Negatively supercoiled simian virus 40 DNA contains Z-DNA segments within transcriptional enhancer sequences. Nature (1983) 5.46
Maize chloroplast DNA fragment encoding the large subunit of ribulosebisphosphate carboxylase. Proc Natl Acad Sci U S A (1977) 5.20
A bifurcated hydrogen-bonded conformation in the d(A.T) base pairs of the DNA dodecamer d(CGCAAATTTGCG) and its complex with distamycin. Proc Natl Acad Sci U S A (1987) 5.14
Simian virus 40 DNA directs synthesis of authentic viral polypeptides in a linked transcription-translation cell-free system. Proc Natl Acad Sci U S A (1975) 4.98
Translational control of protein synthesis in response to heat shock in D. melanogaster cells. Cell (1980) 4.82
Structural analysis of spermine and magnesium ion binding to yeast phenylalanine transfer RNA. Proc Natl Acad Sci U S A (1978) 4.52
Flipping of cloned d(pCpG)n.d(pCpG)n DNA sequences from right- to left-handed helical structure by salt, Co(III), or negative supercoiling. Proc Natl Acad Sci U S A (1982) 4.35
Three-dimensional structure of yeast phenylalanine transfer RNA: folding of the polynucleotide chain. Science (1973) 4.31
The general structure of transfer RNA molecules. Proc Natl Acad Sci U S A (1974) 4.30
Spontaneous assembly of a self-complementary oligopeptide to form a stable macroscopic membrane. Proc Natl Acad Sci U S A (1993) 4.05
Crystal structure of four-stranded Oxytricha telomeric DNA. Nature (1992) 3.96
Negatively supercoiled plasmids contain left-handed Z-DNA segments as detected by specific antibody binding. Cell (1982) 3.80
Antibodies to left-handed Z-DNA bind to interband regions of Drosophila polytene chromosomes. Nature (1981) 3.69
The tetramer d(CpGpCpG) crystallizes as a left-handed double helix. Proc Natl Acad Sci U S A (1980) 3.65
Partial resistance of nascent polypeptide chains to proteolytic digestion due to ribosomal shielding. J Mol Biol (1967) 3.56
Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds. Proc Natl Acad Sci U S A (2000) 3.41
Membrane proteins synthesized but not processed by isolated maize chloroplasts. J Cell Biol (1978) 3.31
The high salt form of poly(dG-dC).poly(dG-dC) is left-handed Z-DNA: Raman spectra of crystals and solutions. Nucleic Acids Res (1981) 3.28
(dC-dA)n.(dG-dT)n sequences have evolutionarily conserved chromosomal locations in Drosophila with implications for roles in chromosome structure and function. EMBO J (1987) 3.28
Pre-proparathyroid hormone: a direct translation product of parathyroid messenger RNA. Proc Natl Acad Sci U S A (1974) 3.24
Underediting of glutamate receptor GluR-B mRNA in malignant gliomas. Proc Natl Acad Sci U S A (2001) 3.14
Chemical probes of DNA conformation: detection of Z-DNA at nucleotide resolution. Cell (1985) 3.10
Antibodies specific for left-handed Z-DNA. Proc Natl Acad Sci U S A (1981) 3.05
Yeast phenylalanine transfer RNA: atomic coordinates and torsion angles. Nucleic Acids Res (1975) 3.04
Three-dimensional structure of yeast phenylalanine transfer RNA at 3.0angstroms resolution. Nature (1974) 2.85
Double helix at atomic resolution. Nature (1973) 2.84
Ribotoxic stress response: activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the alpha-sarcin/ricin loop in the 28S rRNA. Mol Cell Biol (1997) 2.83
Polyribosomes of growing bacteria. Science (1967) 2.82
The effect of the base sequence on the fine structure of the DNA double helix. Prog Biophys Mol Biol (1986) 2.77
Right-handed and left-handed DNA: studies of B- and Z-DNA by using proton nuclear Overhauser effect and P NMR. Proc Natl Acad Sci U S A (1982) 2.76
Cloning and nucleotide sequence of DNA coding for bovine preproparathyroid hormone. Proc Natl Acad Sci U S A (1979) 2.72
Three-dimensional structure of Escherichia coli initiator tRNAfMet. Nature (1980) 2.70
The B-DNA dodecamer at high resolution reveals a spine of water on sodium. Biochemistry (1998) 2.68
Molecular structure of an anticancer drug-DNA complex: daunomycin plus d(CpGpTpApCpG). Proc Natl Acad Sci U S A (1980) 2.67
Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase. Circulation (2001) 2.64
Initiator tRNAs have a unique anticodon loop conformation. Proc Natl Acad Sci U S A (1979) 2.62
Chick cytoplasmic actin and muscle actin have different structural genes. Proc Natl Acad Sci U S A (1976) 2.58
The molecular structure of a DNA-triostin A complex. Science (1984) 2.57
Evidence for linkage of a candidate chromosome 1 region to human systemic lupus erythematosus. J Clin Invest (1997) 2.57
Minor groove RNA triplex in the crystal structure of a ribosomal frameshifting viral pseudoknot. Nat Struct Biol (1999) 2.57
High-resolution structure of a DNA helix containing mismatched base pairs. Nature (1985) 2.56
Crystal structure of the Zalpha domain of the human editing enzyme ADAR1 bound to left-handed Z-DNA. Science (1999) 2.54
Induction of the Z conformation in poly(dG-dC).poly(dG-dC) by binding of N-2-acetylaminofluorene to guanine residues. Proc Natl Acad Sci U S A (1981) 2.54
Self-complementary oligopeptide matrices support mammalian cell attachment. Biomaterials (1995) 2.40
A crystalline fragment of the double helix: the structure of the dinucleoside phosphate guanylyl-3',5'-cytidine. Proc Natl Acad Sci U S A (1973) 2.39
Nucleotide sequence of cloned cDNAs encoding human preproparathyroid hormone. Proc Natl Acad Sci U S A (1981) 2.36
A Z-DNA binding domain present in the human editing enzyme, double-stranded RNA adenosine deaminase. Proc Natl Acad Sci U S A (1997) 2.35
Nucleotide sequence of the human parathyroid hormone gene. Proc Natl Acad Sci U S A (1983) 2.35
X-ray structure of a DNA decamer containing 7,8-dihydro-8-oxoguanine. Proc Natl Acad Sci U S A (1995) 2.30
Nucleoside conformations: an analysis of steric barriers to rotation about the glycosidic bond. J Mol Biol (1967) 2.28
Structural comparison of anticancer drug-DNA complexes: adriamycin and daunomycin. Biochemistry (1990) 2.26
RNA double-helical fragments at atomic resolution. I. The crystal and molecular structure of sodium adenylyl-3',5'-uridine hexahydrate. J Mol Biol (1976) 2.25
Pre-proparathyroid hormone: analysis of radioactive tryptic peptides and amino acid sequence. Biochemistry (1976) 2.25
Determinants of repressor/operator recognition from the structure of the trp operator binding site. Nature (1994) 2.22
Direct biochemical mapping of eukaryotic viral DNA by means of a linked transcription-translation cell-free system. Proc Natl Acad Sci U S A (1976) 2.17
Pharmacokinetics of phenylethylacetylurea (pheneturide), an old antiepileptic drug. J Pharmacokinet Biopharm (1979) 2.16
A comparison of the structure of echinomycin and triostin A complexed to a DNA fragment. Nucleic Acids Res (1985) 2.14
Location of the single gene for the large subunit of ribulosebisphosphate carboxylase on the maize chloroplast chromosome. J Biol Chem (1979) 2.12
A UGA termination suppression tRNATrp active in rabbit reticulocytes. Nature (1980) 2.10
Conformational changes of yeast tRNAPhe and E. coli tRNA2Glu as indicated by different nuclease digestion patterns. J Biol Chem (1979) 2.09
RNA double-helical fragments at atomic resolution. II. The crystal structure of sodium guanylyl-3',5'-cytidine nonahydrate. J Mol Biol (1976) 2.07
Pre-proparathyroid hormone; amino acid sequence, chemical synthesis, and some biological studies of the precursor region. Proc Natl Acad Sci U S A (1978) 2.07
Crystal structures of the catalytic domain of human protein kinase associated with apoptosis and tumor suppression. Nat Struct Biol (2001) 2.06
Structure of the DLM-1-Z-DNA complex reveals a conserved family of Z-DNA-binding proteins. Nat Struct Biol (2001) 2.04
Molecular structure of r(GCG)d(TATACGC): a DNA--RNA hybrid helix joined to double helical DNA. Nature (1982) 2.03
Interactions between an anthracycline antibiotic and DNA: molecular structure of daunomycin complexed to d(CpGpTpApCpG) at 1.2-A resolution. Biochemistry (1987) 2.03
The crystal structures of purines, pyrimidines and their intermolecular complexes. Prog Nucleic Acid Res Mol Biol (1970) 2.03
Isolation of Drosophila proteins that bind selectively to left-handed Z-DNA. Proc Natl Acad Sci U S A (1982) 2.01
Proparathyroid hormone: identification of a biosynthetic precursor to parathyroid hormone. Proc Natl Acad Sci U S A (1972) 1.97
Actin associated with membranes from 3T3 mouse fibroblast and HeLa cells. J Cell Biol (1975) 1.93
AT base pairs are less stable than GC base pairs in Z-DNA: the crystal structure of d(m5CGTAm5CG). Cell (1984) 1.91
Conformational influence of the ribose 2'-hydroxyl group: crystal structures of DNA-RNA chimeric duplexes. Biochemistry (1993) 1.91
HEPATIC DYSFUNCTION IN MALARIA. Science (1944) 1.88
Molecular structure of the octamer d(G-G-C-C-G-G-C-C): modified A-DNA. Proc Natl Acad Sci U S A (1982) 1.88