Rick M Maizels

Author PubWeight™ 96.63‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Diversity and dialogue in immunity to helminths. Nat Rev Immunol 2011 3.72
2 Suppression of allergic airway inflammation by helminth-induced regulatory T cells. J Exp Med 2005 3.63
3 Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity. Mol Biochem Parasitol 2009 2.95
4 Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway. J Exp Med 2010 2.54
5 Chitinase and Fizz family members are a generalized feature of nematode infection with selective upregulation of Ym1 and Fizz1 by antigen-presenting cells. Infect Immun 2005 2.51
6 CD11c depletion severely disrupts Th2 induction and development in vivo. J Exp Med 2010 2.26
7 Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo. J Immunol 2005 2.17
8 Helminth infections and host immune regulation. Clin Microbiol Rev 2012 2.02
9 The secretome of the filarial parasite, Brugia malayi: proteomic profile of adult excretory-secretory products. Mol Biochem Parasitol 2008 1.89
10 Expansion and activation of CD4(+)CD25(+) regulatory T cells in Heligmosomoides polygyrus infection. Eur J Immunol 2007 1.75
11 Alarming dendritic cells for Th2 induction. J Exp Med 2008 1.75
12 IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1. J Exp Med 2013 1.73
13 Helminth-induced CD19+CD23hi B cells modulate experimental allergic and autoimmune inflammation. Eur J Immunol 2010 1.58
14 F4/80+ alternatively activated macrophages control CD4+ T cell hyporesponsiveness at sites peripheral to filarial infection. J Immunol 2006 1.48
15 Expansion of Foxp3+ regulatory T cells in mice infected with the filarial parasite Brugia malayi. J Immunol 2008 1.47
16 Regulatory T cells in human geohelminth infection suppress immune responses to BCG and Plasmodium falciparum. Eur J Immunol 2010 1.45
17 Selective maturation of dendritic cells by Nippostrongylus brasiliensis-secreted proteins drives Th2 immune responses. Eur J Immunol 2004 1.43
18 Defeating sepsis by misleading MyD88. Nat Immunol 2011 1.42
19 Early recruitment of natural CD4+ Foxp3+ Treg cells by infective larvae determines the outcome of filarial infection. Eur J Immunol 2009 1.39
20 T cells in helminth infection: the regulators and the regulated. Trends Immunol 2012 1.39
21 Immunomodulation by helminth parasites: defining mechanisms and mediators. Int J Parasitol 2013 1.38
22 Regulation of allergy and autoimmunity in helminth infection. Clin Rev Allergy Immunol 2004 1.33
23 CTLA-4 and CD4+ CD25+ regulatory T cells inhibit protective immunity to filarial parasites in vivo. J Immunol 2007 1.29
24 Praziquantel treatment of individuals exposed to Schistosoma haematobium enhances serological recognition of defined parasite antigens. J Infect Dis 2005 1.22
25 Linked thioredoxin-glutathione systems in platyhelminths. Trends Parasitol 2004 1.21
26 Cystatins from filarial parasites: evolution, adaptation and function in the host-parasite relationship. Int J Biochem Cell Biol 2007 1.20
27 Chronic helminth infection promotes immune regulation in vivo through dominance of CD11cloCD103- dendritic cells. J Immunol 2011 1.16
28 Proteomic analysis of secretory products from the model gastrointestinal nematode Heligmosomoides polygyrus reveals dominance of venom allergen-like (VAL) proteins. J Proteomics 2011 1.16
29 A pivotal role for CD40-mediated IL-6 production by dendritic cells during IL-17 induction in vivo. J Immunol 2009 1.11
30 A new C-type lectin similar to the human immunoreceptor DC-SIGN mediates symbiont acquisition by a marine nematode. Appl Environ Microbiol 2006 1.10
31 Regulatory T cells induced by parasites and the modulation of allergic responses. Chem Immunol Allergy 2006 1.10
32 Signal sequence analysis of expressed sequence tags from the nematode Nippostrongylus brasiliensis and the evolution of secreted proteins in parasites. Genome Biol 2004 1.10
33 Full-length-enriched cDNA libraries from Echinococcus granulosus contain separate populations of oligo-capped and trans-spliced transcripts and a high level of predicted signal peptide sequences. Mol Biochem Parasitol 2002 1.09
34 Cytokine responses to Schistosoma haematobium in a Zimbabwean population: contrasting profiles for IFN-gamma, IL-4, IL-5 and IL-10 with age. BMC Infect Dis 2007 1.09
35 Heterologous expression of the filarial nematode alt gene products reveals their potential to inhibit immune function. BMC Biol 2005 1.08
36 Regulatory T cells in human lymphatic filariasis: stronger functional activity in microfilaremics. PLoS Negl Trop Dis 2012 1.07
37 Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus. Semin Immunopathol 2012 1.06
38 Age-related and infection intensity-related shifts in antibody recognition of defined protein antigens in a schistosome-exposed population. J Infect Dis 2008 1.05
39 Homologues of human macrophage migration inhibitory factor from a parasitic nematode. Gene cloning, protein activity, and crystal structure. J Biol Chem 2002 1.04
40 Regulatory and activated T cells in human Schistosoma haematobium infections. PLoS One 2011 1.02
41 IL-6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo. Eur J Immunol 2013 1.01
42 Bm-CPI-2, a cystatin from Brugia malayi nematode parasites, differs from Caenorhabditis elegans cystatins in a specific site mediating inhibition of the antigen-processing enzyme AEP. Mol Biochem Parasitol 2005 1.01
43 Suppression of type 2 immunity and allergic airway inflammation by secreted products of the helminth Heligmosomoides polygyrus. Eur J Immunol 2012 1.00
44 Comparison of IgG-ELISA and IgG4-ELISA for Toxocara serodiagnosis. Acta Trop 2005 0.98
45 A transcriptomic analysis of Echinococcus granulosus larval stages: implications for parasite biology and host adaptation. PLoS Negl Trop Dis 2012 0.98
46 Type 2 innate immunity in helminth infection is induced redundantly and acts autonomously following CD11c(+) cell depletion. Infect Immun 2012 0.97
47 Analyzing airway inflammation with chemical biology: dissection of acidic mammalian chitinase function with a selective drug-like inhibitor. Chem Biol 2011 0.96
48 Cutting edge: in the absence of TGF-β signaling in T cells, fewer CD103+ regulatory T cells develop, but exuberant IFN-γ production renders mice more susceptible to helminth infection. J Immunol 2012 0.96
49 Th2 induction by Nippostrongylus secreted antigens in mice deficient in B cells, eosinophils or MHC Class I-related receptors. Immunol Lett 2005 0.95
50 ICOS controls Foxp3(+) regulatory T-cell expansion, maintenance and IL-10 production during helminth infection. Eur J Immunol 2013 0.94
51 IL-4R signaling is required to induce IL-10 for the establishment of T(h)2 dominance. Int Immunol 2006 0.94
52 Schistosome infection intensity is inversely related to auto-reactive antibody levels. PLoS One 2011 0.94
53 Heligmosomoides polygyrus elicits a dominant nonprotective antibody response directed against restricted glycan and peptide epitopes. J Immunol 2011 0.93
54 Immuno-epidemiology of human Schistosoma haematobium infection: preferential IgG3 antibody responsiveness to a recombinant antigen dependent on age and parasite burden. BMC Infect Dis 2006 0.93
55 O-methylated glycans from Toxocara are specific targets for antibody binding in human and animal infections. Int J Parasitol 2006 0.93
56 Abundant larval transcript-1 and -2 genes from Brugia malayi: diversity of genomic environments but conservation of 5' promoter sequences functional in Caenorhabditis elegans. Mol Biochem Parasitol 2002 0.92
57 Oesophagostomum dentatum extract modulates T cell-dependent immune responses to bystander antigens and prevents the development of allergy in mice. PLoS One 2013 0.91
58 MIF homologues from a filarial nematode parasite synergize with IL-4 to induce alternative activation of host macrophages. J Leukoc Biol 2009 0.91
59 Forum: Immunology: Allergy challenged. Nature 2012 0.90
60 Heligmosomoides polygyrus: one species still. Trends Parasitol 2010 0.90
61 Antibodies and IL-3 support helminth-induced basophil expansion. Proc Natl Acad Sci U S A 2012 0.90
62 Four abundant novel transcript genes from Toxocara canis with unrelated coding sequences share untranslated region tracts implicated in the control of gene expression. Mol Biochem Parasitol 2008 0.89
63 Helminths and immunological tolerance. Transplantation 2014 0.89
64 Wild immunology: converging on the real world. Ann N Y Acad Sci 2011 0.89
65 A family of diverse Kunitz inhibitors from Echinococcus granulosus potentially involved in host-parasite cross-talk. PLoS One 2009 0.89
66 Secretion of protective antigens by tissue-stage nematode larvae revealed by proteomic analysis and vaccination-induced sterile immunity. PLoS Pathog 2013 0.89
67 Dynamics of CD11c(+) dendritic cell subsets in lymph nodes draining the site of intestinal nematode infection. Immunol Lett 2009 0.88
68 Vaccination against helminth parasite infections. Expert Rev Vaccines 2014 0.87
69 C-type lectins from the nematode parasites Heligmosomoides polygyrus and Nippostrongylus brasiliensis. Parasitol Int 2009 0.86
70 Developmental regulation and extracellular release of a VSG expression-site-associated gene product from Trypanosoma brucei bloodstream forms. J Cell Sci 2010 0.86
71 Characterization of a UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase with an unusual lectin domain from the platyhelminth parasite Echinococcus granulosus. Biochem J 2004 0.84
72 Th2 responses to helminth parasites can be therapeutically enhanced by, but are not dependent upon, GITR-GITR ligand costimulation in vivo. J Immunol 2011 0.83
73 Resistance to helminth infection: the case for interleukin-5-dependent mechanisms. J Infect Dis 2004 0.81
74 Real-time PCR detection of the HhaI tandem DNA repeat in pre- and post-patent Brugia malayi Infections: a study in Indonesian transmigrants. Parasit Vectors 2014 0.81
75 Lymphatic filariasis and Brugia timori: prospects for elimination. Trends Parasitol 2004 0.78
76 Gain of function in the immune system caused by a ryanodine receptor 1 mutation. J Cell Sci 2013 0.77
77 Myeloid Cell Phenotypes in Susceptibility and Resistance to Helminth Parasite Infections. Microbiol Spectr 2016 0.76
78 Addendum: Defeating sepsis by misleading MyD88. Nat Immunol 2011 0.75
79 Prevention of birch pollen-related food allergy by mucosal treatment with multi-allergen-chimers in mice. PLoS One 2012 0.75
80 Generating EST libraries: trans-spliced cDNAs. Methods Mol Biol 2009 0.75
81 Inflammatory Bowel Disease. Evol Med Public Health 2014 0.75
82 Molecular helminthology: an integrated approach. Am J Trop Med Hyg 2002 0.75
83 Molecular and cellular biology of helminth parasites IV. Int J Parasitol 2006 0.75
84 Erratum: Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. Nat Commun 2015 0.75
85 Corrigendum: CCR7-dependent trafficking of RORγ(+) ILCs creates a unique microenvironment within mucosal draining lymph nodes. Nat Commun 2016 0.75