Published in Mech Ageing Dev on January 12, 2010
Telomeres shorten at equivalent rates in somatic tissues of adults. Nat Commun (2013) 2.56
Leukocyte telomere length in healthy Caucasian and African-American adolescents: relationships with race, sex, adiposity, adipokines, and physical activity. J Pediatr (2010) 1.50
An investigation into the relationship between age and physiological function in highly active older adults. J Physiol (2015) 1.47
Shorter leukocyte telomere length in midlife women with poor sleep quality. J Aging Res (2011) 1.26
An intricate dance: Life experience, multisystem resiliency, and rate of telomere decline throughout the lifespan. Soc Personal Psychol Compass (2012) 1.01
Physical activity and telomere biology: exploring the link with aging-related disease prevention. J Aging Res (2011) 0.98
An integrative review of factors associated with telomere length and implications for biobehavioral research. Nurs Res (2013) 0.97
Telomere length and long-term endurance exercise: does exercise training affect biological age? A pilot study. PLoS One (2012) 0.95
The effect of physiological stimuli on sarcopenia; impact of Notch and Wnt signaling on impaired aged skeletal muscle repair. Int J Biol Sci (2012) 0.94
Aging and brain rejuvenation as systemic events. J Neurochem (2014) 0.93
Physical fitness and telomere length in patients with coronary heart disease: findings from the Heart and Soul Study. PLoS One (2011) 0.92
Longer leukocyte telomeres are associated with ultra-endurance exercise independent of cardiovascular risk factors. PLoS One (2013) 0.91
Human aging and CD31+ T-cell number, migration, apoptotic susceptibility, and telomere length. J Appl Physiol (1985) (2010) 0.90
Telomeres and atherosclerosis. Cardiovasc J Afr (2012) 0.89
Linking the metabolic state and mitochondrial DNA in chronic disease, health, and aging. Diabetes (2013) 0.89
Acute exercise leads to regulation of telomere-associated genes and microRNA expression in immune cells. PLoS One (2014) 0.88
Chronic exercise modifies age-related telomere dynamics in a tissue-specific fashion. J Gerontol A Biol Sci Med Sci (2012) 0.88
Exercise attenuates the major hallmarks of aging. Rejuvenation Res (2015) 0.87
Telomere length and common disease: study design and analytical challenges. Hum Genet (2015) 0.87
Do telomeres adapt to physiological stress? Exploring the effect of exercise on telomere length and telomere-related proteins. Biomed Res Int (2013) 0.86
Independent and combined effects of dietary weight loss and exercise on leukocyte telomere length in postmenopausal women. Obesity (Silver Spring) (2013) 0.83
Nutrition and lifestyle in healthy aging: the telomerase challenge. Aging (Albany NY) (2016) 0.80
Physical Activity, Physical Fitness, and Leukocyte Telomere Length: The Cardiovascular Health Study. Med Sci Sports Exerc (2015) 0.79
Defining the toxicology of aging. Trends Mol Med (2014) 0.78
Resistance training and redox homeostasis: Correlation with age-associated genomic changes. Redox Biol (2016) 0.76
Sports and Exercise at Different Ages and Leukocyte Telomere Length in Later Life - Data from the Berlin Aging Study II (BASE-II). PLoS One (2015) 0.76
Effect of intensive exercise in early adult life on telomere length in later life in men. J Sports Sci Med (2015) 0.76
Genomic Integrity Is Favourably Affected by High-Intensity Interval Training in an Animal Model of Early-Stage Chronic Kidney Disease. Sports Med Open (2016) 0.75
Regular exercise participation improves genomic stability in diabetic patients: an exploratory study to analyse telomere length and DNA damage. Sci Rep (2017) 0.75
Low estrogen levels and obesity are associated with shorter telomere lengths in pre- and postmenopausal women. J Exerc Rehabil (2016) 0.75
Association between telomere length in blood and mortality in people aged 60 years or older. Lancet (2003) 10.56
Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study. Lancet (2007) 6.57
Leukocyte telomere length and cardiovascular disease in the cardiovascular health study. Am J Epidemiol (2006) 5.28
Telomeres and aging. Physiol Rev (2008) 4.79
Regular aerobic exercise prevents and restores age-related declines in endothelium-dependent vasodilation in healthy men. Circulation (2000) 4.32
The association between physical activity in leisure time and leukocyte telomere length. Arch Intern Med (2008) 3.68
Insulin resistance, oxidative stress, hypertension, and leukocyte telomere length in men from the Framingham Heart Study. Aging Cell (2006) 3.44
Familial aggregation of VO(2max) response to exercise training: results from the HERITAGE Family Study. J Appl Physiol (1985) (1999) 2.89
Telomere length and cardiovascular risk factors in a middle-aged population free of overt cardiovascular disease. Aging Cell (2007) 2.62
Weight loss alone improves conduit and resistance artery endothelial function in young and older overweight/obese adults. Hypertension (2008) 2.17
Familial resemblance for VO2max in the sedentary state: the HERITAGE family study. Med Sci Sports Exerc (1998) 2.11
Telomere biology and cardiovascular disease. Circ Res (2006) 1.96
Prognostic value of leukocyte telomere length in patients with stable coronary artery disease: data from the Heart and Soul Study. Arterioscler Thromb Vasc Biol (2008) 1.92
Cellular senescence: molecular mechanisms, in vivo significance, and redox considerations. Antioxid Redox Signal (2009) 1.60
Relationship between physical activity level, telomere length, and telomerase activity. Med Sci Sports Exerc (2008) 1.55
Effects of physical exercise on myocardial telomere-regulating proteins, survival pathways, and apoptosis. J Am Coll Cardiol (2008) 1.43
Factors impacting human telomere homeostasis and age-related disease. Mech Ageing Dev (2007) 1.28
Exercise training improves the antioxidant enzyme activity with no changes of telomere length. Mech Ageing Dev (2008) 1.13
Chronology versus biology: telomeres, essential hypertension, and vascular aging. Hypertension (2002) 1.08
Leukocyte telomere length is associated with HDL cholesterol levels: The Bogalusa heart study. Atherosclerosis (2009) 1.08
No association between physical activity and telomere length in an elderly Chinese population 65 years and older. Arch Intern Med (2008) 0.98
Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain. Mol Cell Biol (2006) 0.93
Direct evidence of endothelial oxidative stress with aging in humans: relation to impaired endothelium-dependent dilation and upregulation of nuclear factor-kappaB. Circ Res (2007) 3.28
The importance of population-wide sodium reduction as a means to prevent cardiovascular disease and stroke: a call to action from the American Heart Association. Circulation (2011) 2.89
Tetrahydrobiopterin augments endothelium-dependent dilatation in sedentary but not in habitually exercising older adults. J Physiol (2005) 2.86
Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing. J Physiol (2004) 2.75
25-Hydroxyvitamin D deficiency is associated with inflammation-linked vascular endothelial dysfunction in middle-aged and older adults. Hypertension (2010) 2.33
Regular aerobic exercise protects against impaired fasting plasma glucose-associated vascular endothelial dysfunction with aging. Clin Sci (Lond) (2013) 2.22
Endurance exercise performance in Masters athletes: age-associated changes and underlying physiological mechanisms. J Physiol (2007) 2.19
Dietary sodium restriction rapidly improves large elastic artery compliance in older adults with systolic hypertension. Hypertension (2004) 2.17
Weight loss alone improves conduit and resistance artery endothelial function in young and older overweight/obese adults. Hypertension (2008) 2.17
Fenofibrate improves vascular endothelial function by reducing oxidative stress while increasing endothelial nitric oxide synthase in healthy normolipidemic older adults. Hypertension (2012) 2.13
Fatness is a better predictor of cardiovascular disease risk factor profile than aerobic fitness in healthy men. Circulation (2005) 2.01
Overweight and obese humans demonstrate increased vascular endothelial NAD(P)H oxidase-p47(phox) expression and evidence of endothelial oxidative stress. Circulation (2007) 1.99
Nuclear factor-{kappa}B activation contributes to vascular endothelial dysfunction via oxidative stress in overweight/obese middle-aged and older humans. Circulation (2009) 1.99
Aging is associated with greater nuclear NF kappa B, reduced I kappa B alpha, and increased expression of proinflammatory cytokines in vascular endothelial cells of healthy humans. Aging Cell (2008) 1.89
Radial artery tonometry demonstrates arterial stiffness in children with type 1 diabetes. Diabetes Care (2004) 1.81
Vascular endothelial dysfunction with aging: endothelin-1 and endothelial nitric oxide synthase. Am J Physiol Heart Circ Physiol (2009) 1.81
Dietary sodium restriction reverses vascular endothelial dysfunction in middle-aged/older adults with moderately elevated systolic blood pressure. J Am Coll Cardiol (2012) 1.77
Women have lower tonic autonomic support of arterial blood pressure and less effective baroreflex buffering than men. Circulation (2005) 1.75
A 16-week randomized clinical trial of 2000 international units daily vitamin D3 supplementation in black youth: 25-hydroxyvitamin D, adiposity, and arterial stiffness. J Clin Endocrinol Metab (2010) 1.69
Decreased maximal heart rate with aging is related to reduced {beta}-adrenergic responsiveness but is largely explained by a reduction in intrinsic heart rate. J Appl Physiol (1985) (2008) 1.62
Arterial stiffening with ageing is associated with transforming growth factor-β1-related changes in adventitial collagen: reversal by aerobic exercise. J Physiol (2010) 1.51
Tetrahydrobiopterin supplementation enhances carotid artery compliance in healthy older men: a pilot study. Am J Hypertens (2012) 1.51
Xanthine oxidase does not contribute to impaired peripheral conduit artery endothelium-dependent dilatation with ageing. J Physiol (2006) 1.50
Habitual exercise and vascular ageing. J Physiol (2009) 1.50
B6D2F1 Mice are a suitable model of oxidative stress-mediated impaired endothelium-dependent dilation with aging. J Gerontol A Biol Sci Med Sci (2009) 1.49
Nitrite supplementation reverses vascular endothelial dysfunction and large elastic artery stiffness with aging. Aging Cell (2011) 1.49
Invited Review: Dynamic exercise performance in Masters athletes: insight into the effects of primary human aging on physiological functional capacity. J Appl Physiol (1985) (2003) 1.44
A transdisciplinary model integrating genetic, physiological, and psychological correlates of voluntary exercise. Health Psychol (2007) 1.43
Adiposity contributes to differences in left ventricular structure and diastolic function with age in healthy men. J Clin Endocrinol Metab (2003) 1.42
Regular exercise, hormone replacement therapy and the age-related decline in carotid arterial compliance in healthy women. Cardiovasc Res (2003) 1.41
Declines in physiological functional capacity with age: a longitudinal study in peak swimming performance. J Appl Physiol (1985) (2002) 1.38
Exercise protects against myocardial ischemia-reperfusion injury via stimulation of β(3)-adrenergic receptors and increased nitric oxide signaling: role of nitrite and nitrosothiols. Circ Res (2011) 1.35
Impaired flow-mediated dilation with age is not explained by L-arginine bioavailability or endothelial asymmetric dimethylarginine protein expression. J Appl Physiol (1985) (2006) 1.35
Superoxide-lowering therapy with TEMPOL reverses arterial dysfunction with aging in mice. Aging Cell (2012) 1.29
Sex-specific effects of habitual aerobic exercise on brachial artery flow-mediated dilation in middle-aged and older adults. Clin Sci (Lond) (2011) 1.24
Ascorbic acid selectively improves large elastic artery compliance in postmenopausal women. Hypertension (2005) 1.23
Protein expression in vascular endothelial cells obtained from human peripheral arteries and veins. J Vasc Res (2009) 1.22
Greater rate of decline in maximal aerobic capacity with age in endurance-trained than in sedentary men. J Appl Physiol (1985) (2003) 1.20
Effect of resistance training on arterial wave reflection and brachial artery reactivity in normotensive postmenopausal women. Eur J Appl Physiol (2007) 1.20
Basal leg blood flow in healthy women is related to age and hormone replacement therapy status. J Physiol (2002) 1.19
Aerobic exercise reverses arterial inflammation with aging in mice. Am J Physiol Heart Circ Physiol (2011) 1.18
Ascorbic acid does not affect large elastic artery compliance or central blood pressure in young and older men. Am J Physiol Heart Circ Physiol (2004) 1.16
SIRT-1 and vascular endothelial dysfunction with ageing in mice and humans. J Physiol (2011) 1.15
Left ventricular structure and diastolic function with human ageing. Relation to habitual exercise and arterial stiffness. Eur Heart J (2003) 1.15
High-dose ascorbic acid infusion abolishes chronic vasoconstriction and restores resting leg blood flow in healthy older men. J Appl Physiol (1985) (2007) 1.14
High energy flux mediates the tonically augmented beta-adrenergic support of resting metabolic rate in habitually exercising older adults. J Clin Endocrinol Metab (2004) 1.14
Baroreflex buffering is reduced with age in healthy men. Circulation (2003) 1.13
MicroRNA changes in human arterial endothelial cells with senescence: relation to apoptosis, eNOS and inflammation. Exp Gerontol (2011) 1.13
Habitually exercising older men do not demonstrate age-associated vascular endothelial oxidative stress. Aging Cell (2011) 1.13
Translational evidence that impaired autophagy contributes to arterial ageing. J Physiol (2012) 1.12
Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice. Aging Cell (2013) 1.11
Sodium nitrite de-stiffening of large elastic arteries with aging: role of normalization of advanced glycation end-products. Exp Gerontol (2012) 1.10
Regular aerobic exercise and the age-related increase in carotid artery intima-media thickness in healthy men. J Appl Physiol (1985) (2002) 1.09
Battery of behavioral tests in mice that models age-associated changes in human motor function. Age (Dordr) (2014) 1.09
Salicylate treatment improves age-associated vascular endothelial dysfunction: potential role of nuclear factor kappaB and forkhead Box O phosphorylation. J Gerontol A Biol Sci Med Sci (2011) 1.08
Effect of exercise training on endothelial function in men with coronary artery disease. Am J Cardiol (2004) 1.07
Vascular endothelial estrogen receptor alpha is modulated by estrogen status and related to endothelial function and endothelial nitric oxide synthase in healthy women. J Clin Endocrinol Metab (2009) 1.07
Pulse wave analysis of the aortic pressure waveform in severe left ventricular systolic dysfunction. Circ Heart Fail (2009) 1.06
Modulation of vascular endothelial function by low-density lipoprotein cholesterol with aging: influence of habitual exercise. Am J Hypertens (2008) 1.06
Changes in maximal aerobic capacity with age in endurance-trained women: 7-yr follow-up. J Appl Physiol (1985) (2002) 1.06
Oxidative stress explains differences in large elastic artery compliance between sedentary and habitually exercising postmenopausal women. Menopause (2006) 1.05
Vascular endothelial function is related to white blood cell count and myeloperoxidase among healthy middle-aged and older adults. Hypertension (2010) 1.03
Life-long caloric restriction elicits pronounced protection of the aged myocardium: a role for AMPK. Mech Ageing Dev (2010) 1.03
Use of acetylene breathing to determine cardiac output in young and older adults. Med Sci Sports Exerc (2003) 1.01
Cytochrome P-450 2C9 signaling does not contribute to age-associated vascular endothelial dysfunction in humans. J Appl Physiol (1985) (2008) 1.01
Arterial intima-media thickness: site-specific associations with HRT and habitual exercise. Am J Physiol Heart Circ Physiol (2002) 1.00
Low dietary sodium intake is associated with enhanced vascular endothelial function in middle-aged and older adults with elevated systolic blood pressure. Ther Adv Cardiovasc Dis (2009) 1.00
Curcumin ameliorates arterial dysfunction and oxidative stress with aging. Exp Gerontol (2012) 0.98
Ascorbic acid increases cardiovagal baroreflex sensitivity in healthy older men. Am J Physiol Heart Circ Physiol (2004) 0.98
The influence of aging on the human sympathetic nervous system and brain norepinephrine turnover. Am J Physiol Regul Integr Comp Physiol (2002) 0.95
The autophagy enhancer spermidine reverses arterial aging. Mech Ageing Dev (2013) 0.95
Role of NFkappaB in age-related vascular endothelial dysfunction in humans. Aging (Albany NY) (2009) 0.94
Plasma norepinephrine is an independent predictor of vascular endothelial function with aging in healthy women. J Appl Physiol (1985) (2011) 0.93
Role of sympathetic neural activation in age- and habitual exercise-related differences in the thermic effect of food. J Clin Endocrinol Metab (2004) 0.92
Inorganic nitrite supplementation for healthy arterial aging. J Appl Physiol (1985) (2014) 0.91
Oxidative stress does not modulate metabolic rate or skeletal muscle sympathetic activity with primary aging in adult humans. J Clin Endocrinol Metab (2003) 0.91
Vascular smooth muscle responsiveness to nitric oxide is reduced in healthy adults with increased adiposity. Am J Physiol Heart Circ Physiol (2012) 0.91
Dietary sodium restriction and association with urinary marinobufagenin, blood pressure, and aortic stiffness. Clin J Am Soc Nephrol (2013) 0.91
Localized increase of chemokines in the lumen of human cerebral aneurysms. Stroke (2013) 0.90
Oxidative stress contributes to chronic leg vasoconstriction in estrogen-deficient postmenopausal women. J Appl Physiol (1985) (2006) 0.90
Vascular health in the ageing athlete. Exp Physiol (2012) 0.88
Increased abdominal-to-peripheral fat distribution contributes to altered autonomic-circulatory control with human aging. Am J Physiol Heart Circ Physiol (2004) 0.87
Influence of ageing on the sympathetic nervous system and adrenal medulla at rest and during stress. Biogerontology (2002) 0.87
Thermogenic responsiveness to beta-adrenergic stimulation is augmented in exercising versus sedentary adults: role of oxidative stress. J Physiol (2005) 0.86
Increased proinflammatory and oxidant gene expression in circulating mononuclear cells in older adults: amelioration by habitual exercise. Physiol Genomics (2011) 0.86
Thermic effect of food and beta-adrenergic thermogenic responsiveness in habitually exercising and sedentary healthy adult humans. J Appl Physiol (1985) (2007) 0.85
Habitual aerobic exercise is associated with smaller femoral artery intima-media thickness with age in healthy men and women. Eur J Cardiovasc Prev Rehabil (2006) 0.85