Published in Immunol Cell Biol on January 12, 2010
Signaling thresholds govern heterogeneity in IL-7-receptor-mediated responses of naïve CD8(+) T cells. Immunol Cell Biol (2011) 1.14
The immunomodulatory properties of the CD5 lymphocyte receptor in health and disease. Curr Opin Immunol (2011) 1.05
Interleukin-7 and immune reconstitution in cancer patients: a new paradigm for dramatically increasing overall survival. Target Oncol (2012) 0.98
Antimicrobial activity and probable mechanisms of action of medicinal plants of Kenya: Withania somnifera, Warbugia ugandensis, Prunus africana and Plectrunthus barbatus. PLoS One (2013) 0.90
IL-21 promotes CD4 T cell responses by phosphatidylinositol 3-kinase-dependent upregulation of CD86 on B cells. J Immunol (2014) 0.87
T-cell modulatory properties of CD5 and its role in antitumor immune responses. Oncoimmunology (2013) 0.87
Post-thymic regulation of CD5 levels in human memory T cells is inversely associated with the strength of responsiveness to interleukin-15. Hum Immunol (2011) 0.79
Interleukin-7 is required for CD4(+) T cell activation and autoimmune neuroinflammation. Clin Immunol (2015) 0.76
Greater frequency of CD5-negative CD8(+) T cells against human immunodeficiency virus type 1 than other viruses is consistent with adaptation to antigenic variation. AIDS Res Ther (2014) 0.76
Forced co-expression of IL-21 and IL-7 in whole-cell cancer vaccines promotes antitumor immunity. Sci Rep (2016) 0.75
Peripheral residence of naïve CD4 T cells induces MHC class II-dependent alterations in phenotype and function. BMC Biol (2014) 0.75
T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis. Nat Med (2010) 4.78
Regulation of heterochromatic DNA replication by histone H3 lysine 27 methyltransferases. Nature (2010) 1.63
Autoinhibition of the kit receptor tyrosine kinase by the cytosolic juxtamembrane region. Mol Cell Biol (2003) 1.40
Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation. Proc Natl Acad Sci U S A (2012) 1.40
Lithium prevents and ameliorates experimental autoimmune encephalomyelitis. J Immunol (2008) 1.34
The tumor suppressor activity of SOCS-1. Oncogene (2002) 1.29
Regulation of the immune system by SOCS family adaptor proteins. Semin Immunol (2004) 1.22
MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration. J Neurosci (2013) 1.21
Critical requirement of CD11b (Mac-1) on T cells and accessory cells for development of experimental autoimmune encephalomyelitis. J Immunol (2005) 1.20
The 3BP2 adapter protein is required for optimal B-cell activation and thymus-independent type 2 humoral response. Mol Cell Biol (2007) 1.18
SOCS1 links cytokine signaling to p53 and senescence. Mol Cell (2009) 1.18
Impaired post-thymic development of regulatory CD4+25+ T cells contributes to diabetes pathogenesis in BB rats. J Immunol (2005) 1.16
IL-6, in synergy with IL-7 or IL-15, stimulates TCR-independent proliferation and functional differentiation of CD8+ T lymphocytes. J Immunol (2008) 1.14
Loss of LFA-1, but not Mac-1, protects MRL/MpJ-Fas(lpr) mice from autoimmune disease. Am J Pathol (2004) 1.12
Kif18B interacts with EB1 and controls astral microtubule length during mitosis. Mol Biol Cell (2011) 1.11
Interferon-β exacerbates Th17-mediated inflammatory disease. Trends Immunol (2011) 1.10
The immunomodulatory properties of the CD5 lymphocyte receptor in health and disease. Curr Opin Immunol (2011) 1.05
Cutting edge: critical role for CD5 in experimental autoimmune encephalomyelitis: inhibition of engagement reverses disease in mice. J Immunol (2004) 1.05
Marginal zone precursor B cells as cellular agents for type I IFN-promoted antigen transport in autoimmunity. J Immunol (2009) 1.02
CD5 plays an inhibitory role in the suppressive function of murine CD4(+) CD25(+) T(reg) cells. Immunol Lett (2008) 0.99
SOCS1, a novel interaction partner of p53 controlling oncogene-induced senescence. Aging (Albany NY) (2010) 0.98
Type I interferons: beneficial in Th1 and detrimental in Th17 autoimmunity. Clin Rev Allergy Immunol (2013) 0.98
Cytokine synergy in antigen-independent activation and priming of naive CD8+ T lymphocytes. Crit Rev Immunol (2009) 0.98
The B cell coreceptor CD22 associates with AP50, a clathrin-coated pit adapter protein, via tyrosine-dependent interaction. J Immunol (2003) 0.97
Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis. J Immunol (2013) 0.97
GIMAP5 regulates mitochondrial integrity from a distinct subcellular compartment. Biochem Biophys Res Commun (2007) 0.97
Increased numbers of thymic and peripheral CD4+ CD25+Foxp3+ cells in the absence of CD5 signaling. Eur J Immunol (2009) 0.96
Suppressor of cytokine signaling 1 stringently regulates distinct functions of IL-7 and IL-15 in vivo during T lymphocyte development and homeostasis. J Immunol (2006) 0.96
Regulation of IL-21 signaling by suppressor of cytokine signaling-1 (SOCS1) in CD8(+) T lymphocytes. Cell Signal (2006) 0.95
Antigen-nonspecific activation of CD8+ T lymphocytes by cytokines: relevance to immunity, autoimmunity, and cancer. Arch Immunol Ther Exp (Warsz) (2008) 0.94
Requirement of the Fc receptor common gamma-chain for gamma delta T cell-mediated promotion of murine experimental autoimmune encephalomyelitis. Eur J Immunol (2005) 0.92
CD5-dependent CK2 activation pathway regulates threshold for T cell anergy. J Immunol (2012) 0.92
GTPase of the immune-associated nucleotide-binding protein 5 (GIMAP5) regulates calcium influx in T-lymphocytes by promoting mitochondrial calcium accumulation. Biochem J (2013) 0.89
Pro-B cells sense productive immunoglobulin heavy chain rearrangement irrespective of polypeptide production. Proc Natl Acad Sci U S A (2011) 0.89
Protein-free diets do not protect high-incidence diabetes-prone BioBreeding rats from diabetes. Metabolism (2002) 0.89
SOCS1 controls liver regeneration by regulating HGF signaling in hepatocytes. J Hepatol (2011) 0.88
Lithium controls central nervous system autoimmunity through modulation of IFN-γ signaling. PLoS One (2012) 0.87
Rescue of tumor-infiltrating lymphocytes from activation-induced cell death enhances the antitumor CTL response in CD5-deficient mice. J Immunol (2011) 0.86
Exposure to IL-15 and IL-21 enables autoreactive CD8 T cells to respond to weak antigens and cause disease in a mouse model of autoimmune diabetes. J Immunol (2011) 0.86
Suppressor of cytokine signaling 1 attenuates IL-15 receptor signaling in CD8+ thymocytes. Blood (2003) 0.86
Janus-like effects of type I interferon in autoimmune diseases. Immunol Rev (2012) 0.86
Suppressor of cytokine signaling 1 regulates IL-15 receptor signaling in CD8+CD44high memory T lymphocytes. J Immunol (2003) 0.85
The interdependent, overlapping, and differential roles of type I and II IFNs in the pathogenesis of experimental autoimmune encephalomyelitis. J Immunol (2013) 0.85
Loss of GIMAP5 (GTPase of immunity-associated nucleotide binding protein 5) impairs calcium signaling in rat T lymphocytes. Mol Immunol (2008) 0.82
AP2 adaptor complex-dependent internalization of CD5: differential regulation in T and B cells. J Immunol (2002) 0.82
Serine phosphorylation of FcγRI cytoplasmic domain directs lipid raft localization and interaction with protein 4.1G. J Leukoc Biol (2011) 0.81
The carboxy-terminal region of CD5 is required for c-CBL mediated TCR signaling downmodulation in thymocytes. Biochem Biophys Res Commun (2013) 0.81
Green tea: a new option for the prevention or control of osteoarthritis. Arthritis Res Ther (2011) 0.80
CD5 enhances Th17-cell differentiation by regulating IFN-γ response and RORγt localization. Eur J Immunol (2014) 0.79
The role of child life in pediatric pain management: a survey of child life specialists. J Pain (2008) 0.78
Regulation of MET receptor signaling by SOCS1 and its implications for hepatocellular carcinoma. Curr Pharm Des (2014) 0.78
Plasmodium falciparum merozoite surface protein 1. Eur J Biochem (2003) 0.77
Betaglycan (TβRIII) is expressed in the thymus and regulates T cell development by protecting thymocytes from apoptosis. PLoS One (2012) 0.77
Increased generation of CD8 single positive cells in SOCS1-deficient thymus does not proportionately increase their export. Immunol Lett (2010) 0.76
SOCS1 prevents potentially skin-reactive cytotoxic T lymphocytes from gaining the ability to cause inflammatory lesions. J Invest Dermatol (2013) 0.76
Correction: Deficiency of Interleukin-15 Confers Resistance to Obesity by Diminishing Inflammation and Enhancing the Thermogenic Function of Adipose Tissues. PLoS One (2016) 0.75
Expression of Interferon-γ Receptor Genes in Peripheral Blood Mononuclear Cells Is Associated With Rheumatoid Arthritis and Its Radiographic Severity in African Americans. Arthritis Rheumatol (2015) 0.75
Erratum: USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation. Nat Immunol (2016) 0.75